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Extract from the Register of European Patents

EP About this file: EP3146968

EP3146968 - K2 COMPOSITION, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF [Right-click to bookmark this link]
StatusThe patent has been granted
Status updated on  03.11.2023
Database last updated on 15.06.2024
FormerGrant of patent is intended
Status updated on  21.06.2023
FormerExamination is in progress
Status updated on  14.06.2019
FormerRequest for examination was made
Status updated on  24.02.2017
FormerThe international publication has been made
Status updated on  16.11.2016
Most recent event   Tooltip24.05.2024Lapse of the patent in a contracting state
New state(s): LV, NL
published on 26.06.2024 [2024/26]
Applicant(s)For all designated states
Sinphar Tian-li Pharmaceutical Co., Ltd. (Hangzhou)
No. 599 Hongfeng Road Yuhang Economic Development Zone Hangzhou
Zhejiang 311100 / CN
[2017/13]
Inventor(s)01 / LIN, Hang-Ching
No.599 Hongfeng Road
Yuhang Economic Development Zone
Hangzhou Zhejiang 311100 / CN
02 / HUANG, Hsin-Wen
No.599 Hongfeng Road
Yuhang Economic Development Zone
Hangzhou Zhejiang 311100 / CN
03 / LU, Shih-Min
No.599 Hongfeng Road
Yuhang Economic Development Zone
Hangzhou Zhejiang 311100 / CN
 [2017/13]
Representative(s)dompatent von Kreisler Selting Werner - Partnerschaft von Patent- und Rechtsanwälten mbB
Deichmannhaus am Dom
Bahnhofsvorplatz 1
50667 Köln / DE
[2017/13]
Application number, filing date15795482.721.05.2015
[2017/13]
WO2015CN79439
Priority number, dateUS201462001328P21.05.2014         Original published format: US 201462001328 P
US201462001737P22.05.2014         Original published format: US 201462001737 P
[2017/13]
Filing languageZH
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015176665
Date:26.11.2015
Language:ZH
[2015/47]
Type: A1 Application with search report 
No.:EP3146968
Date:29.03.2017
Language:EN
[2017/13]
Type: B1 Patent specification 
No.:EP3146968
Date:06.12.2023
Language:EN
[2023/49]
Search report(s)International search report - published on:CN26.11.2015
(Supplementary) European search report - dispatched on:EP21.12.2017
ClassificationIPC:A61K31/575, A61P35/00, A61K36/076
[2018/04]
CPC:
A61K36/076 (EP,KR,US); A61K31/575 (EP,KR,US); A61P11/00 (EP);
A61P35/00 (EP); A61P35/02 (EP); C07J9/005 (EP,KR,US);
A61K2236/00 (EP,US) (-)
Former IPC [2017/13]A61K31/575, A61P35/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/13]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
TitleGerman:K2-ZUSAMMENSETZUNG, HERSTELLUNGSVERFAHREN DAFÜR UND ANWENDUNG DAVON[2017/13]
English:K2 COMPOSITION, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF[2017/13]
French:COMPOSITION K2, PROCÉDÉ POUR LA PRÉPARER ET APPLICATION DE CELLE-CI[2017/13]
Entry into regional phase16.11.2016Translation filed 
16.11.2016National basic fee paid 
16.11.2016Search fee paid 
16.11.2016Designation fee(s) paid 
16.11.2016Examination fee paid 
Examination procedure10.12.2015Request for preliminary examination filed
International Preliminary Examining Authority: CN
16.11.2016Examination requested  [2017/13]
16.11.2016Date on which the examining division has become responsible
10.07.2018Amendment by applicant (claims and/or description)
18.06.2019Despatch of a communication from the examining division (Time limit: M04)
21.08.2019Reply to a communication from the examining division
21.09.2020Cancellation of oral proceeding that was planned for 29.09.2020
24.09.2020Despatch of a communication from the examining division (Time limit: M06)
29.09.2020Date of oral proceedings (cancelled)
01.04.2021Reply to a communication from the examining division
17.03.2023Despatch of a communication from the examining division (Time limit: M02)
05.05.2023Reply to a communication from the examining division
22.06.2023Communication of intention to grant the patent
27.10.2023Fee for grant paid
27.10.2023Fee for publishing/printing paid
27.10.2023Receipt of the translation of the claim(s)
Fees paidRenewal fee
31.03.2017Renewal fee patent year 03
16.05.2018Renewal fee patent year 04
28.05.2019Renewal fee patent year 05
26.03.2020Renewal fee patent year 06
07.05.2021Renewal fee patent year 07
31.03.2022Renewal fee patent year 08
29.03.2023Renewal fee patent year 09
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Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipES06.12.2023
HR06.12.2023
LT06.12.2023
LV06.12.2023
NL06.12.2023
RS06.12.2023
SE06.12.2023
BG06.03.2024
NO06.03.2024
GR07.03.2024
[2024/26]
Former [2024/24]ES06.12.2023
HR06.12.2023
LT06.12.2023
RS06.12.2023
SE06.12.2023
BG06.03.2024
NO06.03.2024
GR07.03.2024
Former [2024/21]LT06.12.2023
BG06.03.2024
GR07.03.2024
Former [2024/20]GR07.03.2024
Documents cited:Search[IY]CN1329900  (INST OF MEDICINE BIO TECHNOLOG [CN]) [I] 11,12 * claims 1-13 * [Y] 2;
 [XY]CN1977866  (TANG ZONGJIAN [CN]) [X] 8-12 * claim 1 * [Y] 2,13,14;
 [IY]EP2246047  (SINPHAR TIAN LI PHARMACEUTICAL [CN]) [I] 8-14 * claims 1-3, 9, 12 * * example 3 * * examples 7-8 * [Y] 2,13,14;
 [IY]EP2305268  (SINPHAR TIAN LI PHARMACEUTICAL CO LTD HANGZHOU [CN]) [I] 8-12 * example 2 * * claims 1-17 * [Y] 2;
 [XI]  - TAI TAKAAKI ET AL, "Isolation of lanostane-type triterpene acids having an acetoxyl group from sclerotia of Poria cocos", PHYTOCHEMISTRY, PERGAMON PRESS, GB, (19950101), vol. 40, no. 1, doi:10.1016/0031-9422(95)00182-7, ISSN 0031-9422, pages 225 - 231, XP002666236 [X] 2,4,5,8-12 * Complete hydrolysis of 3b; page 230, column right, paragraph 6th * [I] 6

DOI:   http://dx.doi.org/10.1016/0031-9422(95)00182-7
 [XY]  - Liang Zhou, "Cytotoxic and Anti-oxidant Activities of Lanostane-Type Triterpenes Isolated from Poria cocos", Chem Pharm Bull, (20081001), pages 1459 - 1462, URL: https://www.jstage.jst.go.jp/article/cpb/56/10/56_10_1459/_pdf/-char/en, (20171130), XP055430592 [X] 8-14 * table 2; compounds 4, 6 * [Y] 13,14

DOI:   http://dx.doi.org/10.1248/cpb.56.1459
 [XY]  - HUI LING ET AL, "Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells", MOLECULAR CARCINOGENESIS, US, (20090601), vol. 48, no. 6, doi:10.1002/mc.20487, ISSN 0899-1987, pages 498 - 507, XP055430800 [X] 8-14 * the whole document * [Y] 13,14

DOI:   http://dx.doi.org/10.1002/mc.20487
 [T]  - BO-FENG CHU ET AL, "An ethanol extract of Poria cocos inhibits the proliferation of non-small cell lung cancer A549 cells via the mitochondria-mediated caspase activation pathway", JOURNAL OF FUNCTIONAL FOODS, NL, (20160501), vol. 23, doi:10.1016/j.jff.2016.03.016, ISSN 1756-4646, pages 614 - 627, XP055430794 [T] 1-14 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.jff.2016.03.016
International search[XY]WO2009155730  (SINPHAR TIAN LI PHARMACEUTICAL [CN]) [X] 1-14 * , description, pages7-8, description, pages 7-8 * [Y] 15-16;
 [Y]WO2010127557  (SINPHAR TIAN LI PHARMACEUTICAL [CN]) [Y] 15-16 * , description, pages 6 and 8-10 *;
 [A]  - ZAN, JUNFENG, "Study on antitumor activity of Poria cocos triterpene compositions and the quality analysis of Poria cocos medicinal materials", MEDICINE & PUBLIC HEALTH, CHINA DOCTORAL DISSERTATIONS FULL-TEXT DATABASE, (20130115), pages E057 - 17, XP 008185337 [A] 1-16
 [A]  - HE, SHAN, "Study on the effective constituents and the effects of anti tumor cell multidrug resistance in the anti tumor cells", MEDICINE & PUBLIC HEALTH, CHINA MASTER'S THESES FULL-TEXT DATABASE, (20120715), pages E057 - 140, XP008185338 [A] 1-16
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.