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Extract from the Register of European Patents

EP About this file: EP3161482

EP3161482 - METHOD FOR ENRICHING CNS-DERIVED EXOSOMES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  02.07.2021
Database last updated on 15.06.2024
FormerThe patent has been granted
Status updated on  24.07.2020
FormerGrant of patent is intended
Status updated on  09.03.2020
FormerExamination is in progress
Status updated on  18.01.2019
FormerRequest for examination was made
Status updated on  31.03.2017
FormerThe international publication has been made
Status updated on  10.03.2017
Most recent event   Tooltip14.06.2024Lapse of the patent in a contracting state
New state(s): TR		published on 17.07.2024 [2024/29]
Applicant(s)For all designated states
XY Evergreen Technology Company
Building 1, Room 2-2-236
Beijing Haidian District District Garden
Beijing / CN
[2017/18]
Inventor(s)01 / ZHANG, Jing
7420 92nd PL SE
Mercer Island, Washington 98040 / US
 [2017/18]
Representative(s)Zimmermann, Tankred Klaus, et al
Schoppe, Zimmermann, Stöckeler
Zinkler, Schenk & Partner mbB
Patentanwälte
Radlkoferstrasse 2
81373 München / DE
[2017/18]
Application number, filing date15811137.726.06.2015
[2017/18]
WO2015US38108
Priority number, dateUS201462018081P27.06.2014         Original published format: US 201462018081 P
[2017/18]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015200851
Date:30.12.2015
Language:EN
[2015/52]
Type: A1 Application with search report 
No.:EP3161482
Date:03.05.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 30.12.2015 takes the place of the publication of the European patent application.
[2017/18]
Type: B1 Patent specification 
No.:EP3161482
Date:26.08.2020
Language:EN
[2020/35]
Search report(s)International search report - published on:US30.12.2015
(Supplementary) European search report - dispatched on:EP25.10.2017
ClassificationIPC:G01N33/68
[2017/47]
CPC:
G01N33/6896 (EP,US); G01N2800/2821 (EP,US); G01N2800/2828 (EP,US);
G01N2800/2835 (EP,US)
Former IPC [2017/18]G01N33/53
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/18]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
TitleGerman:VERFAHREN ZUR ANREICHERUNG VON EXOSOMEN AUS DEM ZNS[2017/18]
English:METHOD FOR ENRICHING CNS-DERIVED EXOSOMES[2017/18]
French:PROCÉDÉ POUR ENRICHIR DES EXOSOMES DÉRIVÉS DU SYSTÈME NERVEUX CENTRAL[2017/18]
Entry into regional phase14.07.2016National basic fee paid 
14.07.2016Search fee paid 
14.07.2016Designation fee(s) paid 
14.07.2016Examination fee paid 
Examination procedure14.07.2016Examination requested  [2017/18]
14.07.2016Date on which the examining division has become responsible
11.05.2018Amendment by applicant (claims and/or description)
17.01.2019Despatch of a communication from the examining division (Time limit: M04)
17.05.2019Reply to a communication from the examining division
30.01.2020Date of oral proceedings
02.03.2020Minutes of oral proceedings despatched
10.03.2020Communication of intention to grant the patent
16.07.2020Fee for grant paid
16.07.2020Fee for publishing/printing paid
16.07.2020Receipt of the translation of the claim(s)
Opposition(s)27.05.2021No opposition filed within time limit [2021/31]
Fees paidRenewal fee
23.06.2017Renewal fee patent year 03
25.06.2018Renewal fee patent year 04
26.06.2019Renewal fee patent year 05
15.06.2020Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU26.06.2015
AL26.08.2020
AT26.08.2020
CY26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
ES26.08.2020
FI26.08.2020
HR26.08.2020
IT26.08.2020
LT26.08.2020
LV26.08.2020
MC26.08.2020
MK26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
TR26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
[2024/29]
Former [2024/22]HU26.06.2015
AL26.08.2020
AT26.08.2020
CY26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
ES26.08.2020
FI26.08.2020
HR26.08.2020
IT26.08.2020
LT26.08.2020
LV26.08.2020
MC26.08.2020
MK26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2023/30]HU26.06.2015
AL26.08.2020
AT26.08.2020
CY26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
ES26.08.2020
FI26.08.2020
HR26.08.2020
IT26.08.2020
LT26.08.2020
LV26.08.2020
MC26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2023/27]HU26.06.2015
AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
ES26.08.2020
FI26.08.2020
HR26.08.2020
IT26.08.2020
LT26.08.2020
LV26.08.2020
MC26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2022/08]AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
ES26.08.2020
FI26.08.2020
HR26.08.2020
IT26.08.2020
LT26.08.2020
LV26.08.2020
MC26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/36]AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
ES26.08.2020
FI26.08.2020
HR26.08.2020
IT26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/34]AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
ES26.08.2020
FI26.08.2020
HR26.08.2020
IT26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/28]AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
ES26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/25]AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
ES26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/23]AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/22]CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/21]DK26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RS26.08.2020
SE26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/12]FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RS26.08.2020
SE26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/10]FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
PL26.08.2020
RS26.08.2020
SE26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/09]FI26.08.2020
LT26.08.2020
SE26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
PT28.12.2020
Former [2021/08]FI26.08.2020
LT26.08.2020
SE26.08.2020
BG26.11.2020
NO26.11.2020
PT28.12.2020
Former [2021/07]FI26.08.2020
LT26.08.2020
NO26.11.2020
Documents cited:Search[Y]US2008241924  (PRIMIANO THOMAS [US], et al) [Y] 1-7 * paragraph [0007] *;
 [Y]US2010184046  (KLASS MICHAEL [US], et al) [Y] 1-7 * paragraphs [0129] , [ 218] *;
 [Y]  - M. W. GRANER ET AL, "Proteomic and immunologic analyses of brain tumor exosomes", THE FASEB JOURNAL, US, (20081224), vol. 23, no. 5, doi:10.1096/fj.08-122184, ISSN 0892-6638, pages 1541 - 1557, XP055416153 [Y] 1-7 * figure 3 *

DOI:   http://dx.doi.org/10.1096/fj.08-122184
 [XPY]  - MIN SHI ET AL, "Plasma exosomal [alpha]-synuclein is likely CNS-derived and increased in Parkinson's disease", ACTA NEUROPATHOLOGICA., BERLIN, DE, (20140706), vol. 128, no. 5, doi:10.1007/s00401-014-1314-y, ISSN 0001-6322, pages 639 - 650, XP055225837 [XP] 1-5 * page 641, section "Exosome isolation"; page 648, left-hand column, last 5 lines; * [Y] 6,7

DOI:   http://dx.doi.org/10.1007/s00401-014-1314-y
 [Y]  - S. SAMAN ET AL, "Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease", JOURNAL OF BIOLOGICAL CHEMISTRY, (20111104), vol. 287, no. 6, doi:10.1074/jbc.M111.277061, ISSN 0021-9258, pages 3842 - 3849, XP055089563 [Y] 6,7 * abstract *

DOI:   http://dx.doi.org/10.1074/jbc.M111.277061
 [A]  - KENNETH W WITWER ET AL, "Standardization of sample collection,isolation and analysis methods in extracellular vesicle research", JOURNAL OF EXTRACELLULAR VESI, COACTION PUBLISHING, SE, vol. 2, doi:10.3402/JEV.V2I0.20360, ISSN 2001-3078, (20130527), page 25pp, (20130527), XP007923200 [A] 1-7 * the whole document *

DOI:   http://dx.doi.org/10.3402/jev.v2i0.20360
International search[Y]US2008241924  (PRIMIANO THOMAS [US], et al) [Y] 1-11 * ; paragraphs [0008], [0018], [0026] *;
 [Y]US2010184046  (KLASS MICHAEL [US], et al) [Y] 1-11 * ; abstract; paragraphs [0010]-[0012], [0054], [0056], [0057], [0099], [0106], [0116], [0130], [0133], [0134], [0148], [0214], [0218], [0232], [0256], [0519], [0528], [0533], [0715], [0815]; Claim 227 *;
 [A]WO2014059052  (UAB RESEARCH FOUNDATION [US]) [A] 1-11 * ; abstract *;
 [PX]US2015119278  (GOETZL EDWARD J [US]) [PX] 1-11* ; abstract *
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