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Extract from the Register of European Patents

EP About this file: EP3170893

EP3170893 - METHOD FOR EXTRACTING DIFFERENTIATED CELLS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  14.01.2022
Database last updated on 30.10.2024
FormerThe patent has been granted
Status updated on  05.02.2021
FormerGrant of patent is intended
Status updated on  20.10.2020
FormerExamination is in progress
Status updated on  02.10.2020
FormerGrant of patent is intended
Status updated on  09.09.2020
FormerExamination is in progress
Status updated on  16.11.2018
FormerRequest for examination was made
Status updated on  21.04.2017
FormerThe international publication has been made
Status updated on  14.02.2017
Most recent event   Tooltip06.09.2024Lapse of the patent in a contracting state
New state(s): MT		published on 09.10.2024  [2024/41]
Applicant(s)For all designated states
Kyoto University
36-1, Yoshida-honmachi Sakyo-ku
Kyoto-shi, Kyoto 606-8501 / JP
[2017/21]
Inventor(s)01 / SAITO, Hirohide
c/o KYOTO UNIVERSITY
36-1 Yoshida-honmachi
Sakyo-ku
Kyoto-shi Kyoto 606-8501 / JP
02 / ENDO, Kei
c/o KYOTO UNIVERSITY
36-1 Yoshida-honmachi
Sakyo-ku
Kyoto-shi Kyoto 606-8501 / JP
03 / KATAYAMA, Shota
c/o KYOTO UNIVERSITY
36-1 Yoshida-honmachi
Sakyo-ku
Kyoto-shi Kyoto 606-8501 / JP
04 / PARR, Callum
c/o KYOTO UNIVERSITY
36-1 Yoshida-honmachi
Sakyo-ku
Kyoto-shi Kyoto 606-8501 / JP
 [2017/21]
Representative(s)HGF
HGF Limited
1 City Walk
Leeds LS11 9DX / GB
[N/P]
Former [2021/10]HGF
1 City Walk
Leeds LS11 9DX / GB
Former [2017/21]HGF Limited
4th Floor
Merchant Exchange
17-19 Whitworth Street West
Manchester M1 5WG / GB
Application number, filing date15822080.616.07.2015
[2017/21]
WO2015JP70425
Priority number, dateJP2014014607016.07.2014         Original published format: JP 2014146070
[2017/21]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016010119
Date:21.01.2016
Language:JA
[2016/03]
Type: A1 Application with search report 
No.:EP3170893
Date:24.05.2017
Language:EN
[2017/21]
Type: B1 Patent specification 
No.:EP3170893
Date:10.03.2021
Language:EN
[2021/10]
Search report(s)International search report - published on:JP21.01.2016
(Supplementary) European search report - dispatched on:EP11.12.2017
ClassificationIPC:C12N5/071, C12N5/00, C12N5/0793
[2018/02]
CPC:
C12N5/0619 (EP,US); C12N15/85 (US); C12N5/0696 (US);
C12N2501/385 (EP,US); C12N2501/65 (EP,US); C12N2506/45 (EP,US);
C12N2510/00 (EP,US); C12N2533/50 (EP,US) (-)
Former IPC [2017/21]C12N5/071, C12N5/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/21]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
TitleGerman:VERFAHREN ZUR EXTRAKTION DIFFERENZIERTER ZELLEN[2017/21]
English:METHOD FOR EXTRACTING DIFFERENTIATED CELLS[2017/21]
French:PROCÉDÉ D'EXTRACTION DE CELLULES DIFFÉRENCIÉES[2017/21]
Entry into regional phase14.02.2017Translation filed 
14.02.2017National basic fee paid 
14.02.2017Search fee paid 
14.02.2017Designation fee(s) paid 
14.02.2017Examination fee paid 
Examination procedure14.02.2017Examination requested  [2017/21]
14.02.2017Date on which the examining division has become responsible
11.07.2018Amendment by applicant (claims and/or description)
20.11.2018Despatch of a communication from the examining division (Time limit: M06)
22.05.2019Reply to a communication from the examining division
03.12.2019Despatch of a communication from the examining division (Time limit: M04)
31.03.2020Reply to a communication from the examining division
10.09.2020Communication of intention to grant the patent
02.10.2020Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
21.10.2020Communication of intention to grant the patent
02.02.2021Fee for grant paid
02.02.2021Fee for publishing/printing paid
02.02.2021Receipt of the translation of the claim(s)
Opposition(s)13.12.2021No opposition filed within time limit [2022/07]
Fees paidRenewal fee
09.06.2017Renewal fee patent year 03
22.05.2018Renewal fee patent year 04
31.05.2019Renewal fee patent year 05
06.07.2020Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU16.07.2015
AL10.03.2021
AT10.03.2021
CY10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
HR10.03.2021
IT10.03.2021
LT10.03.2021
LV10.03.2021
MC10.03.2021
MK10.03.2021
MT10.03.2021
NL10.03.2021
PL10.03.2021
RO10.03.2021
RS10.03.2021
SI10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
IE16.07.2021
LU16.07.2021
BE31.07.2021
[2024/41]
Former [2024/22]HU16.07.2015
AL10.03.2021
AT10.03.2021
CY10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
HR10.03.2021
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LT10.03.2021
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MC10.03.2021
MK10.03.2021
NL10.03.2021
PL10.03.2021
RO10.03.2021
RS10.03.2021
SI10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
IE16.07.2021
LU16.07.2021
BE31.07.2021
Former [2023/30]HU16.07.2015
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CZ10.03.2021
DK10.03.2021
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SI10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
IE16.07.2021
LU16.07.2021
BE31.07.2021
Former [2023/29]HU16.07.2015
AL10.03.2021
AT10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
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MC10.03.2021
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PL10.03.2021
RO10.03.2021
RS10.03.2021
SI10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
IE16.07.2021
LU16.07.2021
BE31.07.2021
Former [2022/35]AL10.03.2021
AT10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
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FI10.03.2021
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MC10.03.2021
NL10.03.2021
PL10.03.2021
RO10.03.2021
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SI10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
IE16.07.2021
LU16.07.2021
BE31.07.2021
Former [2022/34]AL10.03.2021
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SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
LU16.07.2021
BE31.07.2021
Former [2022/23]AL10.03.2021
AT10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
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SM10.03.2021
BG10.06.2021
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PT12.07.2021
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Documents cited:Search[A]EP2202309  (UNIV KYOTO [JP]) [A] 1-7 * the whole document *;
 [I]  - MASAKAZU KAMATA ET AL, "Live Cell Monitoring of hiPSC Generation and Differentiation Using Differential Expression of Endogenous microRNAs", PLOS ONE, (20100728), vol. 5, no. 7, doi:10.1371/journal.pone.0011834, page e11834, XP055430054 [I] 1-7 * figures 6, 7 *

DOI:   http://dx.doi.org/10.1371/journal.pone.0011834
 [Y]  - DEEPA SUBRAMANYAM ET AL, "Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells", NATURE BIOTECHNOLOGY (ADVANCE ONLINE PUBLICATION), (20110413), vol. 29, no. 5, doi:10.1038/nbt.1862, ISSN 1087-0156, pages 443 - 448, XP055429927 [Y] 1-7 * the whole document *

DOI:   http://dx.doi.org/10.1038/nbt.1862
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DOI:   http://dx.doi.org/10.1016/J.STEM.2010.08.012
 [T]  - PARR CALLUM J C ET AL, "MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells", SCIENTIFIC REPORTS, MACMILLAN PUBLISHERS LIMITED, PART OF SPRINGER NATURE, UK, (20160909), vol. 6, ISSN 2045-2322, page 32532, XP002772612 [T] * the whole document *

DOI:   http://dx.doi.org/10.1038/srep32532
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DOI:   http://dx.doi.org/10.1016/j.biomaterials.2017.02.033
 [T]  - KENJI MIKI ET AL, "Efficient Detection and Purification of Cell Populations Using Synthetic MicroRNA Switches", CELL STEM CELL, AMSTERDAM, NL, (20150601), vol. 16, no. 6, doi:10.1016/j.stem.2015.04.005, ISSN 1934-5909, pages 699 - 711, XP055225629 [T] * the whole document *

DOI:   http://dx.doi.org/10.1016/j.stem.2015.04.005
International search[A]JP2009171861  (JAPAN HEALTH SCIENCE FOUND) [A] 1-7 * , entire text (Family: none) *;
 [YA]JP2010158171  (UNIV KYOTO) [Y] 3, 7 * , entire text & US 2009/0246875 A1 & EP 2202309 A1 * [A] 1-2, 4-6;
 [A]US2013150256  (SYNNERGREN JANE [SE], et al) [A] 1-7 * , entire text & WO 2011/154553 A2 & EP 2580328 A2 *;
 [YA]WO2013188679  (STEMGENT INC [US], et al) [Y] 3, 7 * , entire text & EP 2861612 A1 & JP 2015-522257 A * [A] 1-2, 4-6;
 [T]WO2015105172  (UNIV KYOTO [JP]) [T] 1-7* , entire text (Family: none) *;
 [Y]  - DIEKMANN U. et al., "MicroRNA target sites as genetic tools to enhance promoter-reporter specificity for the purification of pancreatic progenitor cells from differentiated embryonic stem cells.", Stem Cell Rev., pages 555 - 68, XP055385673 [Y] 1-7

DOI:   http://dx.doi.org/10.1007/s12015-012-9416-1
 [Y]  - WARREN L. et al., "Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.", Cell Stem Cell, vol. 7, no. 5, doi:doi:10.1016/J.STEM.2010.08.012, pages 618 - 30, XP002640639 [Y] 1-7 * . *

DOI:   http://dx.doi.org/10.1016/J.STEM.2010.08.012
 [T]  - MIKI K. et al., "Efficient Detection and Purification of Cell Populations Using Synthetic MicroRNA Switches.", Cell Stem Cell ., vol. 16, no. 6, doi:doi:10.1016/j.stem.2015.04.005, pages 699 - 711, XP 055225629 [T] 1-7 * . *
 [T]  - KENJI MIKI et al., "Efficient detection and purification of cells by synthetic microRNA switches", Regenerative Medicine, vol. 14, pages 188 O - 04-5, XP 008185727 [T] 1-7
Examination   - R. Sachdeva ET AL, "Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, US, (20100607), vol. 107, no. 25, doi:10.1073/pnas.1006568107, ISSN 0027-8424, pages 11602 - 11607, XP055487790

DOI:   http://dx.doi.org/10.1073/pnas.1006568107
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