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EP About this file: EP3233900

EP3233900 - CHIMERIC ANTIGEN RECEPTORS AND METHODS OF USE THEREOF [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  03.04.2018
Database last updated on 03.09.2024
FormerRequest for examination was made
Status updated on  22.09.2017
FormerThe international publication has been made
Status updated on  21.07.2017
Most recent event   Tooltip27.12.2023New entry: Renewal fee paid 
Applicant(s)For all designated states
Dana-Farber Cancer Institute, Inc.
450 Brookline Avenue
Boston, MA 02215 / US
[2017/43]
Inventor(s)01 / MARASCO, Wayne, A.
43 Rice Street
Wellesley, MA 02481 / US
 [2017/43]
Representative(s)Barker Brettell LLP
100 Hagley Road
Edgbaston
Birmingham B16 8QQ / GB
[N/P]
Former [2017/43]Cooley (UK) LLP
Dashwood
69 Old Broad Street
London EC2M 1QS / GB
Application number, filing date15828615.321.12.2015
[2017/43]
WO2015US67225
Priority number, dateUS201462094625P19.12.2014         Original published format: US 201462094625 P
US201562252083P06.11.2015         Original published format: US 201562252083 P
[2017/43]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2016100985
Date:23.06.2016
Language:EN
[2016/25]
Type: A2 Application without search report 
No.:EP3233900
Date:25.10.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 23.06.2016 takes the place of the publication of the European patent application.
[2017/43]
Search report(s)International search report - published on:EP18.08.2016
ClassificationIPC:C07K14/705, C07K19/00, C07K14/735, C07K14/725
[2017/43]
CPC:
C07K14/7051 (EP,IL,KR,US); C07K14/705 (EP,IL,KR,US); C07K14/70521 (EP,IL,KR,US);
C07K14/70535 (EP,IL,KR,US); C07K14/70578 (EP,IL,KR,US); C07K16/2827 (IL,KR);
C07K19/00 (IL,US); C07K2317/622 (IL,KR); C07K2319/02 (EP,IL,KR,US);
C07K2319/03 (EP,IL,KR,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/43]
TitleGerman:CHIMÄRE ANTIGEN-REZEPTOREN UND VERFAHREN ZUR VERWENDUNG DAVON[2017/43]
English:CHIMERIC ANTIGEN RECEPTORS AND METHODS OF USE THEREOF[2017/43]
French:RÉCEPTEURS ANTIGÉNIQUES CHIMÉRIQUES ET LEURS PROCÉDÉS D'UTILISATION[2017/43]
Entry into regional phase19.07.2017National basic fee paid 
19.07.2017Designation fee(s) paid 
19.07.2017Examination fee paid 
Examination procedure19.07.2017Examination requested  [2017/43]
19.07.2017Date on which the examining division has become responsible
16.02.2018Amendment by applicant (claims and/or description)
06.04.2018Despatch of a communication from the examining division (Time limit: M06)
15.10.2018Reply to a communication from the examining division
07.12.2018Despatch of a communication from the examining division (Time limit: M06)
23.05.2019Reply to a communication from the examining division
19.09.2019Despatch of a communication from the examining division (Time limit: M04)
28.01.2020Reply to a communication from the examining division
12.03.2020Observations by third parties
19.05.2020Despatch of a communication from the examining division (Time limit: M04)
15.09.2020Reply to a communication from the examining division
12.01.2021Despatch of a communication from the examining division (Time limit: M06)
12.08.2021Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
21.10.2021Reply to a communication from the examining division
03.05.2023Despatch of a communication from the examining division (Time limit: M06)
13.11.2023Reply to a communication from the examining division
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
21.10.2021Request for further processing filed
21.10.2021Full payment received (date of receipt of payment)
Request granted
02.11.2021Decision despatched
Fees paidRenewal fee
27.12.2017Renewal fee patent year 03
31.12.2018Renewal fee patent year 04
27.12.2019Renewal fee patent year 05
29.03.2021Renewal fee patent year 06
27.12.2021Renewal fee patent year 07
27.12.2022Renewal fee patent year 08
27.12.2023Renewal fee patent year 09
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31.12.202006   M06   Fee paid on   29.03.2021
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Cited inInternational search[A]WO2005044996  (ST JUDE CHILDRENS RES HOSPITAL [US], et al) [A] 1-19 * the whole document *;
 [XI]WO2013154760  (US HEALTH [US]) [X] 1-18 * Whole document, especially the claims * [I] 19;
 [XAI]WO2014011988  (UNIV PENNSYLVANIA [US]) [X] 1-8,10-12,14-18 * Whole document, especially the claims 23-27, 29,31,33 * [A] 20,21 [I] 19;
 [XI]  - CARPENTER R O ET AL, "B-cell Maturation Antigen Is a Promising Target for Adoptive T-cell Therapy of Multiple Myeloma", CLINICAL CANCER RESEARCH, THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, vol. 19, no. 8, doi:10.1158/1078-0432.CCR-12-2422, ISSN 1078-0432, (20130415), pages 2048 - 2060, (20130123), XP002727959 [X] 1-18 * Whole document especially page 2050, left column §2 * [I] 19

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-12-2422
 [XI]  - XIAO-SONG ZHONG ET AL, "Chimeric Antigen Receptors Combining 4-1BB and CD28 Signaling Domains Augment PI3kinase/AKT/Bcl-XL Activation and CD8+ T Cell-mediated Tumor Eradication", MOLECULAR THERAPY, (20100201), vol. 18, no. 2, doi:10.1038/mt.2009.210, ISSN 1525-0016, pages 413 - 420, XP055023623 [X] 1-8,10-12,14-18,20 * Whole document, especially figure 1a * [I] 19

DOI:   http://dx.doi.org/10.1038/mt.2009.210
 [A]  - M. SADELAIN ET AL, "The Basic Principles of Chimeric Antigen Receptor Design", CANCER DISCOVERY, (20130401), vol. 3, no. 4, doi:10.1158/2159-8290.CD-12-0548, ISSN 2159-8274, pages 388 - 398, XP055133523 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1158/2159-8290.CD-12-0548
 [A]  - JULIE R BRAHMER ET AL, "Safety and activity of anti-PD-L1 antibody in patients with advanced cancer", NEW ENGLAND JOURNAL OF MEDICINE, THE - NEJM, MASSACHUSETTS MEDICAL SOCIETY, US, (20120628), vol. 366, no. 26, doi:10.1056/NEJMOA1200694, ISSN 1533-4406, pages 2455 - 2465, XP002685330 [A] 21 * abstract *

DOI:   http://dx.doi.org/10.1056/NEJMoa1200694
 [XP]  - Wayne A Marasco ET AL, "Carbonic Anhydrdase IX: Opportunities for Immune-Based Approaches", (20151107), URL: http://www.euikcs.com/kca/miami/docs/h6-marasco.pdf, (20160411), XP055264162 [XP] 1-21 * the whole document *
by applicantUS5994136
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