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Extract from the Register of European Patents

EP About this file: EP3206683

EP3206683 - NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR ANESTHESIA [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  10.07.2020
Database last updated on 28.09.2024
FormerGrant of patent is intended
Status updated on  21.07.2019
FormerRequest for examination was made
Status updated on  21.07.2017
FormerThe international publication has been made
Status updated on  15.05.2017
Most recent event   Tooltip10.07.2020Application deemed to be withdrawnpublished on 12.08.2020  [2020/33]
Applicant(s)For all designated states
The Board of Trustees of the Leland Stanford Junior University
Office of the General Counsel
Building 170, Third Floor, Main Quad
P.O. Box 20386
Stanford, CA 94305-2038 / US
For all designated states
The United States Government as represented by The Department of Veterans Affairs
810 Vermont Avenue NW
Washington, DC 20420 / US
[2019/38]
Former [2019/33]For all designated states
The Board of Trustees of the Leland Stanford Junior University
Office of Technology Licensing
3000 El Camino Real
Building Five, Suite 300
Palo Alto, CA 94306-2100 / US
For all designated states
The United States Government as represented by The Department of Veterans Affairs
810 Vermont Avenue NV
Washington, DC 20420 / US
Former [2017/34]For all designated states
The Board of Trustees of the Leland Stanford Junior University
Office of Technology Licensing
3000 El Camino Real
Building Five, Third Floor
Palo Alto, CA 94306-1106 / US
For all designated states
The United States Government as represented by The Department of Veterans Affairs
810 Vermont Avenue, N.W.
Office of the General Counsel
Washington, DC 20420 / US
Inventor(s)01 / BERTACCINI, Edward John
1502 Chaumont Dr.
San Jose, California 95118 / US
02 / DAVIES, Margaret Frances
780 E Meadow Dr.
Palo Alto, California 94303 / US
 [2017/34]
Representative(s)Comoglio, Elena, et al
Jacobacci & Partners S.p.A.
Corso Emilia 8
10152 Torino / IT
[2017/34]
Application number, filing date15850730.116.10.2015
[2017/34]
WO2015US56067
Priority number, dateUS201462064670P16.10.2014         Original published format: US 201462064670 P
[2017/34]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016061538
Date:21.04.2016
Language:EN
[2016/16]
Type: A1 Application with search report 
No.:EP3206683
Date:23.08.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 21.04.2016 takes the place of the publication of the European patent application.
[2017/34]
Search report(s)International search report - published on:US21.04.2016
(Supplementary) European search report - dispatched on:EP14.05.2018
ClassificationIPC:A61K31/402, A61K31/40, A61P23/00, C07D207/34
[2018/24]
CPC:
C07D207/34 (EP,US); A61K31/40 (EP,US); A61K31/402 (EP,US);
A61P23/00 (EP); A61P25/20 (EP); A61P25/22 (EP)
Former IPC [2017/34]A61K31/40
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/34]
TitleGerman:NEUARTIGE VERFAHREN, VERBINDUNGEN UND ZUSAMMENSETZUNGEN ZUR ANÄSTHESIE[2017/34]
English:NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR ANESTHESIA[2017/34]
French:NOUVEAUX PROCÉDÉS, COMPOSÉS ET COMPOSITIONS D'ANESTHÉSIE[2017/34]
Entry into regional phase15.05.2017National basic fee paid 
15.05.2017Search fee paid 
15.05.2017Designation fee(s) paid 
15.05.2017Examination fee paid 
Examination procedure15.05.2017Examination requested  [2017/34]
15.05.2017Date on which the examining division has become responsible
04.12.2018Amendment by applicant (claims and/or description)
22.07.2019Communication of intention to grant the patent
03.12.2019Application deemed to be withdrawn, date of legal effect  [2020/33]
15.01.2020Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2020/33]
Fees paidRenewal fee
30.10.2017Renewal fee patent year 03
30.10.2018Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
31.10.201905   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]WO2008002974  (ABBOTT LAB [US], et al) [X] 10,11,16,17 * compounds of cl. 6 *;
 [X]WO2005080328  (ASTRAZENECA AB [SE], et al) [X] 12,13,16,17 * p. 28/29; p. 32 *;
 [X]  - Ende Li ET AL, "Copper-catalyzed synthesis of 1,2,4-trisubstituted pyrroles via cascade reactions of aryloxy-enynes with amines", RSC Advances, doi:10.1039/c3ra44595j, (20130101), page 22872, URL: http://www.rsc.org/suppdata/ra/c3/c3ra44595j/c3ra44595j.pdf, XP055470166 [X] 12,13,16,17 * p. 5 of supplementary information, compound 3g and further compounds on p. 4-8 *

DOI:   http://dx.doi.org/10.1039/c3ra44595j
 [X]  - Ke ET AL, "Supporting Information Oxidative Cross-Coupling/Cyclization to Build Polysubstituted Pyrroles from Terminal Alkynes and ?-Enamino Esters", Chemical Communications (Cambridge, United Kingdom) ( 2013 ), 49(68), 7549-7551, (20130101), URL: http://www.rsc.org/suppdata/cc/c3/c3cc43682a/c3cc43682a.pdf, (20180424), XP055470175 [X] 12,13,16,17 * see compounds on p. 14/15 *
 [X]  - DEMIRAYAK SEREF ET AL, "Synthesis and cytotoxic and analgesic activities of some 1,5-diaryl-3-ethoxycarbonylpyrrole derivatives", JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMI, INFORMA HEALTHCARE, GB, (20060201), vol. 21, no. 1, doi:10.1080/14756360500472845, ISSN 1475-6366, pages 113 - 118, XP008084523 [X] 12,16,17 * see scheme 1, table I, compounds 2a-2c, 2f-2h *

DOI:   http://dx.doi.org/10.1080/14756360500472845
 [X]  - DA EN ET AL, "Nucleophilic Phosphine-Catalyzed Intramolecular Michael Reactions of N -Allylic Substituted [alpha]-Amino Nitriles: Construction of Functionalized Pyrrolidine Rings via 5- endo -trig Cyclizations", JOURNAL OF ORGANIC CHEMISTRY, (20140505), vol. 79, no. 10, doi:10.1021/jo500418s, ISSN 0022-3263, pages 4456 - 4462, XP055470492 [X] 14-17 * p. 4458, scheme 3, compound 10; p. 4461, col. 1, last § *

DOI:   http://dx.doi.org/10.1021/jo500418s
 [A]  - ERVIN PEJO ET AL, "Differential effects of etomidate and its pyrrole analogue carboetomidate on the adrenocortical and cytokine responses to endotoxemia* :", CRITICAL CARE MEDICINE., US, (20120101), vol. 40, no. 1, doi:10.1097/CCM.0b013e31822d7924, ISSN 0090-3493, pages 187 - 192, XP055431528 [A] 1-17 * title, abstract; Fig. 1 *

DOI:   http://dx.doi.org/10.1097/CCM.0b013e31822d7924
International search[X]US2003013754  (MARTINS TIMOTHY J [US], et al) [X] 45-50 * , entire document, especially: para [0110]; para [0120]. *;
 [Y]US2006122230  (BERGGREN ANNA I K [SE], et al) [Y] 1-30, 58-59 * , entire document, especially: para [0001]; para [0093]; para [0162] *;
 [Y]US2986564  (RICHARD RIPS, et al) [Y] 5, 15, 23 * , entire document, especially:col 2, Example I; col 3, Example II *;
 [X]  - PubChem, (20080922), Database accession no. 24894335, URL: NCBI [X] 31-37 * , Fig. *
 [XY]  - PubChem, (20070618), Database accession no. 16111410, URL: NCBI [X] 38-44, 51-57 * , Fig. * [Y] 58-59
 [Y]  - PEJO et al., "Differential Effects of Etomidate and its Pyrrole Analogue Carboetomidate on the Adrenocortical and Cytokine Responses to Endotoxemia", Crit Care Med., (20120000), vol. 40, no. 1, pages 187 - 192, XP 055431528 [Y] 1-30 * , entire document, especially: *
 [A]  - "Anesthesia", WIKIPEDIA, (20140900), pages 1 - 2, XP009502132 [A] 24-27
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.