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Extract from the Register of European Patents

EP About this file: EP3227330

EP3227330 - TDP-43-BINDING POLYPEPTIDES USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES [Right-click to bookmark this link]
StatusThe patent has been granted
Status updated on  15.12.2023
Database last updated on 22.05.2024
FormerGrant of patent is intended
Status updated on  11.08.2023
FormerExamination is in progress
Status updated on  01.08.2023
FormerGrant of patent is intended
Status updated on  30.03.2023
FormerExamination is in progress
Status updated on  29.06.2019
FormerRequest for examination was made
Status updated on  08.09.2017
FormerThe international publication has been made
Status updated on  22.06.2017
Most recent event   Tooltip15.12.2023(Expected) grantpublished on 17.01.2024  [2024/03]
Applicant(s)For all designated states
Université Laval
2325 rue de l'Université
Québec, Québec G1V 0A6 / CA
[2017/41]
Inventor(s)01 / JULIEN, Jean-Pierre
985 Grande-Allée Ouest
Québec, Québec G1S 1E1 / CA
02 / GRAVEL, Claude
3520 Pincourt
Québec, Québec G2B 2E3 / CA
03 / POZZI, Silvia
90 rue de Maisonneuve
Québec, Québec G1R 2C3 / CA
 [2017/41]
Representative(s)Cabinet Becker et Associés
25, rue Louis le Grand
75002 Paris / FR
[2017/41]
Application number, filing date15864525.907.12.2015
[2017/41]
WO2015CA51280
Priority number, dateCA2014287408305.12.2014         Original published format: CA 2874083
US201462088012P05.12.2014         Original published format: US 201462088012 P
[2017/41]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016086320
Date:09.06.2016
Language:EN
[2016/23]
Type: A1 Application with search report 
No.:EP3227330
Date:11.10.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 09.06.2016 takes the place of the publication of the European patent application.
[2017/41]
Type: B1 Patent specification 
No.:EP3227330
Date:17.01.2024
Language:EN
[2024/03]
Search report(s)International search report - published on:CA09.06.2016
(Supplementary) European search report - dispatched on:EP27.09.2018
ClassificationIPC:C07K16/18, A61K39/395, A61P25/16, A61P25/28, C07K16/46, C12N15/13, C12N15/864, C12N5/10
[2017/41]
CPC:
C07K16/18 (EP,US); A61P21/02 (EP); A61P25/00 (EP);
A61P25/16 (EP); A61P25/28 (EP); A61P9/10 (EP);
C12N15/86 (US); A61K48/00 (US); C07K2317/24 (US);
C07K2317/35 (US); C07K2317/52 (US); C07K2317/54 (US);
C07K2317/55 (US); C07K2317/569 (US); C07K2317/622 (EP,US);
C07K2317/76 (EP,US); C07K2317/82 (EP,US); C12N2750/14143 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/41]  
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:TDP-43-BINDENDE POLYPEPTIDE ZUR BEHANDLUNG NEURODEGENERATIVER ERKRANKUNGEN[2017/41]
English:TDP-43-BINDING POLYPEPTIDES USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES[2017/41]
French:POLYPEPTIDES DE LIAISON À TDP-43 UTILES POUR LE TRAITEMENT DE MALADIES NEURODÉGÉNÉRATIVES[2017/41]
Entry into regional phase21.06.2017National basic fee paid 
21.06.2017Search fee paid 
21.06.2017Designation fee(s) paid 
21.06.2017Examination fee paid 
Examination procedure21.06.2017Examination requested  [2017/41]
21.06.2017Date on which the examining division has become responsible
16.04.2019Amendment by applicant (claims and/or description)
03.07.2019Despatch of a communication from the examining division (Time limit: M04)
04.11.2019Reply to a communication from the examining division
21.02.2020Despatch of a communication from the examining division (Time limit: M04)
24.06.2020Reply to a communication from the examining division
23.09.2020Despatch of a communication from the examining division (Time limit: M06)
31.03.2021Reply to a communication from the examining division
17.06.2021Despatch of a communication from the examining division (Time limit: M04)
14.10.2021Reply to a communication from the examining division
28.02.2022Despatch of a communication from the examining division (Time limit: M04)
24.06.2022Reply to a communication from the examining division
31.03.2023Communication of intention to grant the patent
01.08.2023Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
01.08.2023Fee for grant paid
01.08.2023Fee for publishing/printing paid
21.08.2023Communication of intention to grant the patent
11.12.2023Receipt of the translation of the claim(s)
Fees paidRenewal fee
18.12.2017Renewal fee patent year 03
10.12.2018Renewal fee patent year 04
10.12.2019Renewal fee patent year 05
10.12.2020Renewal fee patent year 06
06.12.2021Renewal fee patent year 07
23.12.2022Renewal fee patent year 08
09.10.2023Renewal fee patent year 09
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Documents cited:Search[X]  - LINDA K KWONG ET AL, "Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteins", ACTA NEUROPATHOLOGICA COMMUNICATIONS, BIOMED CENTRAL LTD, LONDON, UK, (20140331), vol. 2, no. 1, doi:10.1186/2051-5960-2-33, ISSN 2051-5960, page 33, XP021182567 [X] 1-10,12-15 * abstract *

DOI:   http://dx.doi.org/10.1186/2051-5960-2-33
 [A]  - GENDRON T F ET AL, "Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration", NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, WILEY-BLACKWELL PUBLISHING LTD, GB, vol. 36, no. 2, doi:10.1111/J.1365-2990.2010.01060.X, ISSN 1365-2990, (20100401), pages 97 - 112, (20100323), XP002658541 [A] 1-10,12-15 * the whole document *

DOI:   http://dx.doi.org/10.1111/J.1365-2990.2010.01060.X
International search[X]WO2012174666  (UNIV LAVAL [CA], et al) [X] 24, 27-36, 39-43 *see the entire document*;
 [A]  - SWARUP, V. et al., "Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor KB-mediated pathogenic pathways.", J. Exp. Med., (20111121), vol. 208, no. 12, ISSN 0022-1007, pages 2429 - 2447, XP055124401 [A] 1-43 * . *see the entire document*

DOI:   http://dx.doi.org/10.1073/pnas.0900688106
Examination   - MATHIEU DONDELINGER ET AL, "Understanding the Significance and Implications of Antibody Numbering and Antigen-Binding Surface/Residue Definition", FRONTIERS IN IMMUNOLOGY, (20181016), vol. 9, doi:10.3389/fimmu.2018.02278, pages 1 - 15, XP055572450

DOI:   http://dx.doi.org/10.3389/fimmu.2018.02278
    - SILVIA POZZI ET AL, "Virus-mediated delivery of antibody targeting TAR DNA-binding protein-43 mitigates associated neuropathology", THE JOURNAL OF CLINICAL INVESTIGATION, GB, (20190225), vol. 129, no. 4, doi:10.1172/JCI123931, ISSN 0021-9738, pages 1581 - 1595, XP055657665

DOI:   http://dx.doi.org/10.1172/JCI123931
by applicantWO8605807
 JPS6296086
 US4683195
 WO8704462
 EP0251744
 EP0258067
 US4857467
 WO8910036
 WO8910404
 WO9001063
 EP0361991
 EP0387319
 US4980286
 WO9106657
 WO9412650
 WO9629411
 US5576195
 US5641670
 WO9852976
 US5846818
 WO2012174666
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.