EP3230744 - COMPOSITIONS AND METHODS FOR PERFORMING METHYLATION DETECTION ASSAYS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 18.03.2022 Database last updated on 09.09.2024 | |
Former | The patent has been granted Status updated on 09.04.2021 | ||
Former | Grant of patent is intended Status updated on 19.01.2021 | ||
Former | Request for examination was made Status updated on 30.11.2020 | ||
Former | Grant of patent is intended Status updated on 13.08.2020 | ||
Former | Request for examination was made Status updated on 15.09.2017 | ||
Former | The international publication has been made Status updated on 16.06.2017 | Most recent event Tooltip | 06.09.2024 | Lapse of the patent in a contracting state New state(s): MT | published on 09.10.2024 [2024/41] | Applicant(s) | For all designated states Exact Sciences Development Company, LLC 5505 Endeavor Lane Madison, Wisconsin 53719 / US | [2021/18] |
Former [2018/02] | For all designated states Exact Sciences Development Company, LLC 441 Charmany Drive Madison, Wisconsin 53719 / US | ||
Former [2017/42] | For all designated states Exact Sciences Corporation 441 Charmany Drive Madison, Wisconsin 53719 / US | Inventor(s) | 01 /
ALLAWI, Hatim T. 901 Winding Way Middleton, Wisconsin 53562 / US | 02 /
LIDGARD, Graham P. 652 Bear Claw Way Apt. 313 Middleton, Wisconsin 53562 / US | [2017/42] | Representative(s) | Glawe, Delfs, Moll Partnerschaft mbB von Patent- und Rechtsanwälten Postfach 13 03 91 20103 Hamburg / DE | [2021/19] |
Former [2017/42] | Glawe, Delfs, Moll Partnerschaft mbB von Patent- und Rechtsanwälten Postfach 13 03 91 20103 Hamburg / DE | Application number, filing date | 15868202.1 | 11.12.2015 | [2017/42] | WO2015US65272 | Priority number, date | US201462091069P | 12.12.2014 Original published format: US 201462091069 P | [2017/42] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2016094813 | Date: | 16.06.2016 | Language: | EN | [2016/24] | Type: | A1 Application with search report | No.: | EP3230744 | Date: | 18.10.2017 | Language: | EN | The application published by WIPO in one of the EPO official languages on 16.06.2016 takes the place of the publication of the European patent application. | [2017/42] | Type: | B1 Patent specification | No.: | EP3230744 | Date: | 12.05.2021 | Language: | EN | [2021/19] | Search report(s) | International search report - published on: | US | 16.06.2016 | (Supplementary) European search report - dispatched on: | EP | 13.06.2018 | Classification | IPC: | G01N33/574, C12Q1/6881, C12Q1/6886 | [2018/28] | CPC: |
C12Q1/6886 (EP,US);
C12Q1/6881 (EP,US);
C12Q2600/112 (US);
C12Q2600/118 (EP,US);
C12Q2600/154 (EP,US);
C12Q2600/158 (EP,US);
C12Q2600/166 (EP)
(-)
|
Former IPC [2017/42] | G01N33/574 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2017/42] | Extension states | BA | Not yet paid | ME | Not yet paid | Validation states | MA | Not yet paid | MD | Not yet paid | Title | German: | VORRICHTUNGEN UND VERFAHREN ZUR DURCHFÜHRUNG VON METHYLIERUNGSERKENNUNGSTESTS | [2017/42] | English: | COMPOSITIONS AND METHODS FOR PERFORMING METHYLATION DETECTION ASSAYS | [2017/42] | French: | COMPOSITIONS ET PROCÉDÉS POUR EFFECTUER DES ESSAIS DE DÉTECTION DE MÉTHYLATION | [2017/42] | Entry into regional phase | 15.06.2017 | National basic fee paid | 15.06.2017 | Search fee paid | 15.06.2017 | Designation fee(s) paid | 15.06.2017 | Examination fee paid | Examination procedure | 15.06.2017 | Examination requested [2017/42] | 15.06.2017 | Date on which the examining division has become responsible | 21.12.2018 | Amendment by applicant (claims and/or description) | 14.08.2020 | Communication of intention to grant the patent | 30.11.2020 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 30.11.2020 | Fee for grant paid | 30.11.2020 | Fee for publishing/printing paid | 27.01.2021 | Communication of intention to grant the patent | 31.03.2021 | Receipt of the translation of the claim(s) | Divisional application(s) | EP21166494.1 / EP3889611 | Opposition(s) | 15.02.2022 | No opposition filed within time limit [2022/16] | Fees paid | Renewal fee | 27.12.2017 | Renewal fee patent year 03 | 31.12.2018 | Renewal fee patent year 04 | 27.12.2019 | Renewal fee patent year 05 | 28.12.2020 | Renewal fee patent year 06 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 11.12.2015 | AL | 12.05.2021 | AT | 12.05.2021 | CY | 12.05.2021 | CZ | 12.05.2021 | DK | 12.05.2021 | EE | 12.05.2021 | FI | 12.05.2021 | HR | 12.05.2021 | LT | 12.05.2021 | LV | 12.05.2021 | MC | 12.05.2021 | MK | 12.05.2021 | MT | 12.05.2021 | NL | 12.05.2021 | PL | 12.05.2021 | RO | 12.05.2021 | RS | 12.05.2021 | SE | 12.05.2021 | SI | 12.05.2021 | SK | 12.05.2021 | SM | 12.05.2021 | TR | 12.05.2021 | BG | 12.08.2021 | NO | 12.08.2021 | GR | 13.08.2021 | IS | 12.09.2021 | PT | 13.09.2021 | LU | 11.12.2021 | BE | 31.12.2021 | CH | 31.12.2021 | LI | 31.12.2021 | [2024/41] |
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LT | 12.05.2021 | Documents cited: | Search | [XI] - Hongchuan Jin ET AL, "Circulating Methylated DNA as Biomarkers for Cancer Detection", Methylation - From DNA, RNA and Histones to Diseases and Treatment, InTech, (20121128), doi:10.5772/51419, ISBN 978-953-51-0881-8, XP055479454 [X] 1-3 * page 139 * * page 143 - page 144 * [I] 4-7 DOI: http://dx.doi.org/10.5772/51419 | [XI] - MOHAMED I. HUSSEINY ET AL, "Tissue-Specific Methylation of Human Insulin Gene and PCR Assay for Monitoring Beta Cell Death", PLOS ONE, (20140410), vol. 9, no. 4, doi:10.1371/journal.pone.0094591, page e94591, XP055197433 [X] 4-7 * page 8; figure 6 * [I] 1-3 DOI: http://dx.doi.org/10.1371/journal.pone.0094591 | [I] - SIRI STRAND ET AL, "Prognostic DNA Methylation Markers for Prostate Cancer", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, (20140918), vol. 15, no. 9, doi:10.3390/ijms150916544, pages 16544 - 16576, XP055479116 [I] 1-15 * page 16562 * DOI: http://dx.doi.org/10.3390/ijms150916544 | [A] - D. A. HABER ET AL, "Blood-Based Analyses of Cancer: Circulating Tumor Cells and Circulating Tumor DNA", CANCER DISCOVERY, (20140506), vol. 4, no. 6, doi:10.1158/2159-8290.CD-13-1014, ISSN 2159-8274, pages 650 - 661, XP055479355 [A] 1-15 * page 4 * DOI: http://dx.doi.org/10.1158/2159-8290.CD-13-1014 | [A] - A. T. J. I. GO ET AL, "Non-invasive aneuploidy detection using free fetal DNA and RNA in maternal plasma: recent progress and future possibilities", HUMAN REPRODUCTION UPDATE, (20101112), vol. 17, no. 3, doi:10.1093/humupd/dmq054, ISSN 1355-4786, pages 372 - 382, XP055052831 [A] 1-15 * page 376; table 1 * DOI: http://dx.doi.org/10.1093/humupd/dmq054 | [A] - BASANT KUMAR THAKUR ET AL, "Double-stranded DNA in exosomes: a novel biomarker in cancer detection", CELL RESEARCH - XIBAO YANJIU, GB, CN, (20140408), vol. 24, no. 6, doi:10.1038/cr.2014.44, ISSN 1001-0602, pages 766 - 769, XP055240739 [A] 1-15 * the whole document * DOI: http://dx.doi.org/10.1038/cr.2014.44 | International search | [XY]US2004234960 (OLEK ALEXANDER [DE], et al) [X] 58-63, 67-69, 109 * entire document * [Y] 64-66; | [XY]US2009191548 (BERLIN KURT [DE], et al) [X] 1-4, 6, 7, 9-16, 18, 19, 21-23, 25-27, 29-41, 43, 44, 46, 70, 96 * entire document * [Y] 5, 8, 17, 20, 24, 28, 42, 45, 82; | [Y]US2009253142 (ALLAWI HATIM T [US], et al) [Y] 8, 20, 28, 45, 64-66* entire document *; | [XY]US2013022974 (CHINNAIYAN ARUL M [US], et al) [X] 47-57, 102, 107 * entire document * [Y] 5, 17, 24, 42, 82 |