EP3150590 - S1P MODULATING AGENTS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 21.08.2020 Database last updated on 19.10.2024 | |
Former | The patent has been granted Status updated on 13.09.2019 | ||
Former | Grant of patent is intended Status updated on 09.04.2019 | ||
Former | Examination is in progress Status updated on 13.04.2018 | ||
Former | Request for examination was made Status updated on 06.10.2017 | ||
Former | The application has been published Status updated on 03.03.2017 | Most recent event Tooltip | 08.07.2022 | Lapse of the patent in a contracting state New state(s): MK | published on 10.08.2022 [2022/32] | Applicant(s) | For all designated states Biogen MA Inc. 225 Binney Street Cambridge, MA 02142 / US | [2019/42] |
Former [2017/14] | For all designated states Biogen MA Inc. 250 Binney Street Cambridge, MA 02142 / US | Inventor(s) | 01 /
THOMAS, Jermaine 130 Library Street Chelsea, MA Massachusetts 02150 / US | 02 /
MI, Sha 4 Vernon Road Belmont, MA Massachusetts 02478 / US | 03 /
LIN, Edward, Yin-shiang 73 Thornton Rd Chestnut Hill, MA Massachusetts 02467 / US | 04 /
ZHENG, Guo, Zhu 14 Meriam Street Lexington, MA Massachusetts 02420 / US | 05 /
MA, Bin 211 Wachusett Ave. Arlington, MA Massachusetts 02476 / US | 06 /
CALDWELL, Richard, D. 8 Alden Street Melrose, MA 02176 / US | 07 /
GUCKIAN, Kevin 44 Little Pond Road Northborough, MA Massachusetts 01532 / US | 08 /
KUMARAVEL, Gnanasambandam 21 Appletree Lane Lexington, MA Massachusetts 02420 / US | [2019/38] |
Former [2019/19] | 01 /
THOMAS, Jermaine 130 Library Street Chelsea, MA Massachusetts 02150 / US | ||
02 /
MI, Sha 4 Vernon Road Belmont, MA Massachusetts 02478 / US | |||
03 /
LIN, Edward, Yin-shiang 73 Thornton Rd Chestnut Hill, MA Massachusetts 02467 / US | |||
04 /
ZHENG, Guo, Zhu 14 Meriam Street Lexington, MA Massachusetts 02420 / US | |||
05 /
MA, Bin 211 Wachusett Ave. Arlington, MA Massachusetts 02476 / US | |||
06 /
CALDWELL, Richard, D. 8 Alden Street Melrose, MA 02176 / US | |||
07 /
GUCKIAN, Kevin 44 Little Pond Road Northborough, MA Massachusetts 01532 / US | |||
08 /
KUMARAVEL, Gnanasambandam 21 Appletree Lane Lexington, MA Massachusetts 02420 / US | |||
Former [2017/15] | 01 /
THOMAS, Jermaine 130 Library Street Chelsea, MA Massachusetts 02150 / US | ||
02 /
MI, Sha 4 Vernon Road Belmont, MA Massachusetts 02478 / US | |||
03 /
LIN, Edward, Yin-shiang 73 Thornton Rd Chestnut Hill, MA Massachusetts 02467 / US | |||
04 /
ZHENG, Guo, Zhu 14 Meriam Street Lexington, MA Massachusetts 02420 / US | |||
05 /
MA, Bin 211 Wachusett Ave. Arlington, MA Massachusetts 02476 / US | |||
06 /
CALDWELL, Richard, D. 8 Alden Street Melrose, MA 02176 / US | |||
07 /
GUCKIAN, Kevin 44 Little Pond Road Northborough, MA Massachusetts 01532 / US | |||
08 /
KUMARAVEL, Gnanasambandam 21 Appletree Lane Lexington, MA Massachusetts 02420 / US | |||
Former [2017/14] | 01 /
THOMAS, Jermaine 130 Library Street Chelsea, MA Massachusetts 02150 / US | ||
02 /
MI, Sha 4 Vernon Road Belmont, MA Massachusetts 02478 / US | |||
03 /
LIN, Edward, Yin-shiang 73 Thornton Rd Chestnut Hill, MA Massachusetts 02467 / US | |||
04 /
ZHENG, Guo, Zhu 14 Meriam Street Lexington, MA Massachusetts 02420 / US | |||
05 /
MA, Bin 211 Wachusett Ave. Arlington, MA Massachusetts 02476 / US | |||
06 /
CALDWELL, Richard, D. 77 Pond Avenue, Apt. 1106 Brookline, MA Massachusetts 02445 / US | |||
07 /
GUCKIAN, Kevin 44 Little Pond Road Northborough, MA Massachusetts 01532 / US | |||
08 /
KUMARAVEL, Gnanasambandam 21 Appletree Lane Lexington, MA Massachusetts 02420 / US | Representative(s) | Miller, David James, et al Mathys & Squire The Shard 32 London Bridge Street London SE1 9SG / GB | [N/P] |
Former [2017/14] | Miller, David James, et al Mathys & Squire LLP The Shard 32 London Bridge Street London SE1 9SG / GB | Application number, filing date | 16183267.0 | 03.02.2012 | [2017/14] | Priority number, date | US201161440254P | 07.02.2011 Original published format: US 201161440254 P | [2017/14] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP3150590 | Date: | 05.04.2017 | Language: | EN | [2017/14] | Type: | B1 Patent specification | No.: | EP3150590 | Date: | 16.10.2019 | Language: | EN | [2019/42] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 04.01.2017 | Classification | IPC: | C07D401/06, C07D405/12, C07D211/34, C07D211/60, C07D211/62, A61K31/55, A61P25/00 | [2017/14] | CPC: |
A61K31/445 (EP,IL,US);
C07D401/06 (EP,CN,IL,KR,US);
C07D211/62 (EP,CN,IL,US);
A61K31/225 (EP,IL,US);
A61K31/4465 (EA);
A61K31/4545 (EP,IL,US);
A61K31/4709 (EP,EA,IL,US);
A61K31/498 (EP,IL,US);
A61K31/517 (EP,IL,KR,US);
A61K31/55 (EP,IL,US);
A61K31/695 (EP,IL,US);
A61K38/21 (EP,IL,US);
A61K39/3955 (IL,US);
A61P1/00 (EP);
A61P1/04 (EP);
A61P11/06 (EP);
A61P17/06 (EP);
A61P19/02 (EP);
A61P21/00 (EP);
A61P21/02 (EP);
A61P25/00 (EP);
A61P25/02 (EP);
A61P25/04 (EP);
A61P25/14 (EP);
A61P25/16 (EP);
A61P25/28 (EP,EA);
A61P29/00 (EP);
A61P29/02 (EP);
A61P3/10 (EP);
A61P31/12 (EP);
A61P35/00 (EP);
A61P35/04 (EP);
A61P37/00 (EP);
A61P37/02 (EP);
A61P37/06 (EP);
A61P43/00 (EP);
A61P7/00 (EP);
A61P9/00 (EP);
A61P9/10 (EP);
C07D211/34 (EP,IL,US);
C07D211/60 (EP,CN,IL,US);
C07D215/20 (EP,IL,US);
C07D405/12 (EP,CN,IL,US);
C07D471/04 (CN);
C07F7/0812 (CN);
C07K16/2842 (IL,US)
(-)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2017/45] |
Former [2017/14] | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR | Extension states | BA | 03.10.2017 | ME | 03.10.2017 | Title | German: | S1P-MODULIERENDE MITTEL | [2017/14] | English: | S1P MODULATING AGENTS | [2017/14] | French: | AGENTS DE MODULATION S1P | [2017/14] | Examination procedure | 08.08.2016 | Date on which the examining division has become responsible | 03.10.2017 | Amendment by applicant (claims and/or description) | 03.10.2017 | Examination requested [2017/45] | 11.04.2018 | Despatch of a communication from the examining division (Time limit: M06) | 27.09.2018 | Reply to a communication from the examining division | 29.10.2018 | Despatch of a communication from the examining division (Time limit: M02) | 21.12.2018 | Reply to a communication from the examining division | 10.04.2019 | Communication of intention to grant the patent | 09.08.2019 | Fee for grant paid | 09.08.2019 | Fee for publishing/printing paid | 09.08.2019 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP12745253.0 / EP2672823 | Divisional application(s) | EP19203412.2 / EP3660010 | Opposition(s) | 17.07.2020 | No opposition filed within time limit [2020/39] | Fees paid | Renewal fee | 08.08.2016 | Renewal fee patent year 03 | 08.08.2016 | Renewal fee patent year 04 | 08.08.2016 | Renewal fee patent year 05 | 27.02.2017 | Renewal fee patent year 06 | 07.02.2018 | Renewal fee patent year 07 | 26.02.2019 | Renewal fee patent year 08 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 03.02.2012 | AL | 16.10.2019 | AT | 16.10.2019 | CY | 16.10.2019 | CZ | 16.10.2019 | DK | 16.10.2019 | EE | 16.10.2019 | FI | 16.10.2019 | HR | 16.10.2019 | LT | 16.10.2019 | LV | 16.10.2019 | MC | 16.10.2019 | MK | 16.10.2019 | MT | 16.10.2019 | NL | 16.10.2019 | PL | 16.10.2019 | RO | 16.10.2019 | RS | 16.10.2019 | SE | 16.10.2019 | SI | 16.10.2019 | SK | 16.10.2019 | SM | 16.10.2019 | TR | 16.10.2019 | BG | 16.01.2020 | NO | 16.01.2020 | GR | 17.01.2020 | IE | 03.02.2020 | LU | 03.02.2020 | IS | 16.02.2020 | PT | 17.02.2020 | BE | 29.02.2020 | CH | 29.02.2020 | LI | 29.02.2020 | [2022/32] |
Former [2022/27] | HU | 03.02.2012 | |
AL | 16.10.2019 | ||
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CY | 16.10.2019 | ||
CZ | 16.10.2019 | ||
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EE | 16.10.2019 | ||
FI | 16.10.2019 | ||
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LT | 16.10.2019 | ||
LV | 16.10.2019 | ||
MC | 16.10.2019 | ||
MT | 16.10.2019 | ||
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PL | 16.10.2019 | ||
RO | 16.10.2019 | ||
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SM | 16.10.2019 | ||
TR | 16.10.2019 | ||
BG | 16.01.2020 | ||
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GR | 17.01.2020 | ||
IE | 03.02.2020 | ||
LU | 03.02.2020 | ||
IS | 16.02.2020 | ||
PT | 17.02.2020 | ||
BE | 29.02.2020 | ||
CH | 29.02.2020 | ||
LI | 29.02.2020 | ||
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MC | 16.10.2019 | ||
NL | 16.10.2019 | ||
PL | 16.10.2019 | ||
RO | 16.10.2019 | ||
RS | 16.10.2019 | ||
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SI | 16.10.2019 | ||
SK | 16.10.2019 | ||
SM | 16.10.2019 | ||
BG | 16.01.2020 | ||
NO | 16.01.2020 | ||
GR | 17.01.2020 | ||
IE | 03.02.2020 | ||
LU | 03.02.2020 | ||
IS | 16.02.2020 | ||
PT | 17.02.2020 | ||
BE | 29.02.2020 | ||
CH | 29.02.2020 | ||
LI | 29.02.2020 | ||
Former [2021/08] | AL | 16.10.2019 | |
AT | 16.10.2019 | ||
CZ | 16.10.2019 | ||
DK | 16.10.2019 | ||
EE | 16.10.2019 | ||
FI | 16.10.2019 | ||
HR | 16.10.2019 | ||
LT | 16.10.2019 | ||
LV | 16.10.2019 | ||
MC | 16.10.2019 | ||
NL | 16.10.2019 | ||
PL | 16.10.2019 | ||
RO | 16.10.2019 | ||
RS | 16.10.2019 | ||
SE | 16.10.2019 | ||
SI | 16.10.2019 | ||
SK | 16.10.2019 | ||
SM | 16.10.2019 | ||
BG | 16.01.2020 | ||
NO | 16.01.2020 | ||
GR | 17.01.2020 | ||
IE | 03.02.2020 | ||
LU | 03.02.2020 | ||
IS | 16.02.2020 | ||
PT | 17.02.2020 | ||
CH | 29.02.2020 | ||
LI | 29.02.2020 | ||
Former [2020/51] | AL | 16.10.2019 | |
AT | 16.10.2019 | ||
CZ | 16.10.2019 | ||
DK | 16.10.2019 | ||
EE | 16.10.2019 | ||
FI | 16.10.2019 | ||
HR | 16.10.2019 | ||
LT | 16.10.2019 | ||
LV | 16.10.2019 | ||
MC | 16.10.2019 | ||
NL | 16.10.2019 | ||
PL | 16.10.2019 | ||
RO | 16.10.2019 | ||
RS | 16.10.2019 | ||
SE | 16.10.2019 | ||
SI | 16.10.2019 | ||
SK | 16.10.2019 | ||
SM | 16.10.2019 | ||
BG | 16.01.2020 | ||
NO | 16.01.2020 | ||
GR | 17.01.2020 | ||
LU | 03.02.2020 | ||
IS | 16.02.2020 | ||
PT | 17.02.2020 | ||
CH | 29.02.2020 | ||
LI | 29.02.2020 | ||
Former [2020/50] | AL | 16.10.2019 | |
AT | 16.10.2019 | ||
CZ | 16.10.2019 | ||
DK | 16.10.2019 | ||
EE | 16.10.2019 | ||
FI | 16.10.2019 | ||
HR | 16.10.2019 | ||
LT | 16.10.2019 | ||
LV | 16.10.2019 | ||
MC | 16.10.2019 | ||
NL | 16.10.2019 | ||
PL | 16.10.2019 | ||
RO | 16.10.2019 | ||
RS | 16.10.2019 | ||
SE | 16.10.2019 | ||
SI | 16.10.2019 | ||
SK | 16.10.2019 | ||
SM | 16.10.2019 | ||
BG | 16.01.2020 | ||
NO | 16.01.2020 | ||
GR | 17.01.2020 | ||
LU | 03.02.2020 | ||
IS | 16.02.2020 | ||
PT | 17.02.2020 | ||
Former [2020/48] | AL | 16.10.2019 | |
AT | 16.10.2019 | ||
CZ | 16.10.2019 | ||
DK | 16.10.2019 | ||
EE | 16.10.2019 | ||
FI | 16.10.2019 | ||
HR | 16.10.2019 | ||
LT | 16.10.2019 | ||
LV | 16.10.2019 | ||
NL | 16.10.2019 | ||
PL | 16.10.2019 | ||
RO | 16.10.2019 | ||
RS | 16.10.2019 | ||
SE | 16.10.2019 | ||
SK | 16.10.2019 | ||
SM | 16.10.2019 | ||
BG | 16.01.2020 | ||
NO | 16.01.2020 | ||
GR | 17.01.2020 | ||
LU | 03.02.2020 | ||
IS | 16.02.2020 | ||
PT | 17.02.2020 | ||
Former [2020/37] | AL | 16.10.2019 | |
AT | 16.10.2019 | ||
CZ | 16.10.2019 | ||
DK | 16.10.2019 | ||
EE | 16.10.2019 | ||
FI | 16.10.2019 | ||
HR | 16.10.2019 | ||
LT | 16.10.2019 | ||
LV | 16.10.2019 | ||
NL | 16.10.2019 | ||
PL | 16.10.2019 | ||
RO | 16.10.2019 | ||
RS | 16.10.2019 | ||
SE | 16.10.2019 | ||
SK | 16.10.2019 | ||
SM | 16.10.2019 | ||
BG | 16.01.2020 | ||
NO | 16.01.2020 | ||
GR | 17.01.2020 | ||
IS | 16.02.2020 | ||
PT | 17.02.2020 | ||
Former [2020/36] | AL | 16.10.2019 | |
AT | 16.10.2019 | ||
CZ | 16.10.2019 | ||
DK | 16.10.2019 | ||
EE | 16.10.2019 | ||
FI | 16.10.2019 | ||
HR | 16.10.2019 | ||
LT | 16.10.2019 | ||
LV | 16.10.2019 | ||
NL | 16.10.2019 | ||
PL | 16.10.2019 | ||
RO | 16.10.2019 | ||
RS | 16.10.2019 | ||
SE | 16.10.2019 | ||
BG | 16.01.2020 | ||
NO | 16.01.2020 | ||
GR | 17.01.2020 | ||
IS | 16.02.2020 | ||
PT | 17.02.2020 | ||
Former [2020/35] | AL | 16.10.2019 | |
AT | 16.10.2019 | ||
CZ | 16.10.2019 | ||
FI | 16.10.2019 | ||
HR | 16.10.2019 | ||
LT | 16.10.2019 | ||
LV | 16.10.2019 | ||
NL | 16.10.2019 | ||
PL | 16.10.2019 | ||
RO | 16.10.2019 | ||
RS | 16.10.2019 | ||
SE | 16.10.2019 | ||
BG | 16.01.2020 | ||
NO | 16.01.2020 | ||
GR | 17.01.2020 | ||
PT | 17.02.2020 | ||
IS | 24.02.2020 | ||
Former [2020/32] | AL | 16.10.2019 | |
AT | 16.10.2019 | ||
FI | 16.10.2019 | ||
HR | 16.10.2019 | ||
LT | 16.10.2019 | ||
LV | 16.10.2019 | ||
NL | 16.10.2019 | ||
PL | 16.10.2019 | ||
RS | 16.10.2019 | ||
SE | 16.10.2019 | ||
BG | 16.01.2020 | ||
NO | 16.01.2020 | ||
GR | 17.01.2020 | ||
PT | 17.02.2020 | ||
IS | 24.02.2020 | ||
Former [2020/25] | AT | 16.10.2019 | |
FI | 16.10.2019 | ||
HR | 16.10.2019 | ||
LT | 16.10.2019 | ||
LV | 16.10.2019 | ||
NL | 16.10.2019 | ||
PL | 16.10.2019 | ||
RS | 16.10.2019 | ||
SE | 16.10.2019 | ||
BG | 16.01.2020 | ||
NO | 16.01.2020 | ||
GR | 17.01.2020 | ||
PT | 17.02.2020 | ||
IS | 24.02.2020 | ||
Former [2020/24] | AT | 16.10.2019 | |
FI | 16.10.2019 | ||
LT | 16.10.2019 | ||
LV | 16.10.2019 | ||
NL | 16.10.2019 | ||
PL | 16.10.2019 | ||
SE | 16.10.2019 | ||
BG | 16.01.2020 | ||
NO | 16.01.2020 | ||
GR | 17.01.2020 | ||
PT | 17.02.2020 | ||
IS | 24.02.2020 | ||
Former [2020/23] | AT | 16.10.2019 | |
FI | 16.10.2019 | ||
LT | 16.10.2019 | ||
LV | 16.10.2019 | ||
NL | 16.10.2019 | ||
PL | 16.10.2019 | ||
SE | 16.10.2019 | ||
BG | 16.01.2020 | ||
NO | 16.01.2020 | ||
GR | 17.01.2020 | ||
PT | 17.02.2020 | ||
Former [2020/22] | FI | 16.10.2019 | |
LT | 16.10.2019 | ||
NL | 16.10.2019 | ||
SE | 16.10.2019 | ||
BG | 16.01.2020 | ||
NO | 16.01.2020 | ||
PT | 17.02.2020 | ||
Former [2020/21] | NL | 16.10.2019 | |
NO | 16.01.2020 | ||
Former [2020/20] | NL | 16.10.2019 | Documents cited: | Search | [A]US2008027036 (BURLI ROLAND [US], et al) [A] 1-18 * Abstract; claims; examples. *; | [Y]US2010160258 (CALDWELL RICHARD D [US], et al) [Y] 1-18 * Abstract; claims. *; | [Y]US2010160357 (CALDWELL RICHARD D [US], et al) [Y] 1-18* Abstract; claims. *; | [Y]US7750021 (MI YUAN [CN], et al) [Y] 1-18 * Column 1, lines 19-30; column 1, line 53 to column 2, line 37, in particular the definition of R1; column 4, lines 24-60; examples e.g. columns 59-60, compound 118. *; | [XPI]WO2011017561 (BIOGEN IDEC INC [US], et al) [XP] 1-11,13-18 * Abstract; claims; examples e.g. pages 35-36, examples 24-25, pages 42-44, examples 39-42. * [I] 12; | [A] - MARSOLAIS, ROSEN, "Chemical modulators of sphingosine-1-phosphate receptors as barrier-oriented therapeutic molecules", NATURE REVIEWS DRUG DISCOVERY, (20090320), vol. 8, no. 4, doi:10.1038/NRD2356, ISSN 1474-1784, pages 297 - 307, XP002617578 [A] 1-18 * the whole document * DOI: http://dx.doi.org/10.1038/NRD2356 | Examination | - ZHANG ET AL., FRONTIERS IN CELLULAR NEUROSCIENCE, (20131029), vol. 7, pages 1 - 7 | by applicant | WO2012109108 | - WANG, W., FASEB J., (2005), vol. 19, no. 12, pages 1731 - 1733 | - NOVGORODOV, A. ET AL., FASEB J, (2007), vol. 21, pages 1503 - 1514 | - RUTISHAUSER ET AL., PHYSIOL. REV., (1988), vol. 68, page 819 | - LEMKE, An Introduction to Molecular Neurobiology, SINAUER, (1992), page 281 | - BRITTIS ET AL., NEURON, (2001), vol. 30, pages 11 - 14 | - JONES ET AL., J. NEUROSCI., (2002), vol. 22, pages 2792 - 2803 | - GRIMPE ET AL., J. NEUROSCI., (2002), vol. 22, pages 3144 - 3160 | - CHEN ET AL., NATURE, (2000), vol. 403, pages 434 - 439 | - GRANDPRE ET AL., NATURE, (2000), vol. 403, pages 439 - 444 | - MCKERRACHER ET AL., NEURON, (1994), vol. 13, pages 805 - 811 | - MUKHOPADHYAY ET AL., NEURON, (1994), vol. 13, pages 757 - 767 | - MIKOL ET AL., J. CELL. BIOL., (1988), vol. 106, pages 1273 - 1279 | - WANG ET AL., NATURE, (2002), vol. 417, pages 941 - 944 | - FOUMIER ET AL., NATURE, (2001), vol. 409, pages 341 - 346 | - CHANG ET AL., N. ENGL. J. MED., (2002), vol. 346, pages 165 - 173 | - DAVIS ET AL., JOURNAL OF BIOLOGICAL CHEMISTRY, (2005), vol. 280, pages 9833 - 9841 | WO2012US23799 |