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Extract from the Register of European Patents

EP About this file: EP3150590

EP3150590 - S1P MODULATING AGENTS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  21.08.2020
Database last updated on 19.10.2024
FormerThe patent has been granted
Status updated on  13.09.2019
FormerGrant of patent is intended
Status updated on  09.04.2019
FormerExamination is in progress
Status updated on  13.04.2018
FormerRequest for examination was made
Status updated on  06.10.2017
FormerThe application has been published
Status updated on  03.03.2017
Most recent event   Tooltip08.07.2022Lapse of the patent in a contracting state
New state(s): MK
published on 10.08.2022  [2022/32]
Applicant(s)For all designated states
Biogen MA Inc.
225 Binney Street
Cambridge, MA 02142 / US
[2019/42]
Former [2017/14]For all designated states
Biogen MA Inc.
250 Binney Street
Cambridge, MA 02142 / US
Inventor(s)01 / THOMAS, Jermaine
130 Library Street
Chelsea, MA Massachusetts 02150 / US
02 / MI, Sha
4 Vernon Road
Belmont, MA Massachusetts 02478 / US
03 / LIN, Edward, Yin-shiang
73 Thornton Rd
Chestnut Hill, MA Massachusetts 02467 / US
04 / ZHENG, Guo, Zhu
14 Meriam Street
Lexington, MA Massachusetts 02420 / US
05 / MA, Bin
211 Wachusett Ave.
Arlington, MA Massachusetts 02476 / US
06 / CALDWELL, Richard, D.
8 Alden Street
Melrose, MA 02176 / US
07 / GUCKIAN, Kevin
44 Little Pond Road
Northborough, MA Massachusetts 01532 / US
08 / KUMARAVEL, Gnanasambandam
21 Appletree Lane
Lexington, MA Massachusetts 02420 / US
 [2019/38]
Former [2019/19]01 / THOMAS, Jermaine
130 Library Street
Chelsea, MA Massachusetts 02150 / US
02 / MI, Sha
4 Vernon Road
Belmont, MA Massachusetts 02478 / US
03 / LIN, Edward, Yin-shiang
73 Thornton Rd
Chestnut Hill, MA Massachusetts 02467 / US
04 / ZHENG, Guo, Zhu
14 Meriam Street
Lexington, MA Massachusetts 02420 / US
05 / MA, Bin
211 Wachusett Ave.
Arlington, MA Massachusetts 02476 / US
06 / CALDWELL, Richard, D.
8 Alden Street
Melrose, MA 02176 / US
07 / GUCKIAN, Kevin
44 Little Pond Road
Northborough, MA Massachusetts 01532 / US
08 / KUMARAVEL, Gnanasambandam
21 Appletree Lane
Lexington, MA Massachusetts 02420 / US
Former [2017/15]01 / THOMAS, Jermaine
130 Library Street
Chelsea, MA Massachusetts 02150 / US
02 / MI, Sha
4 Vernon Road
Belmont, MA Massachusetts 02478 / US
03 / LIN, Edward, Yin-shiang
73 Thornton Rd
Chestnut Hill, MA Massachusetts 02467 / US
04 / ZHENG, Guo, Zhu
14 Meriam Street
Lexington, MA Massachusetts 02420 / US
05 / MA, Bin
211 Wachusett Ave.
Arlington, MA Massachusetts 02476 / US
06 / CALDWELL, Richard, D.
8 Alden Street
Melrose, MA 02176 / US
07 / GUCKIAN, Kevin
44 Little Pond Road
Northborough, MA Massachusetts 01532 / US
08 / KUMARAVEL, Gnanasambandam
21 Appletree Lane
Lexington, MA Massachusetts 02420 / US
Former [2017/14]01 / THOMAS, Jermaine
130 Library Street
Chelsea, MA Massachusetts 02150 / US
02 / MI, Sha
4 Vernon Road
Belmont, MA Massachusetts 02478 / US
03 / LIN, Edward, Yin-shiang
73 Thornton Rd
Chestnut Hill, MA Massachusetts 02467 / US
04 / ZHENG, Guo, Zhu
14 Meriam Street
Lexington, MA Massachusetts 02420 / US
05 / MA, Bin
211 Wachusett Ave.
Arlington, MA Massachusetts 02476 / US
06 / CALDWELL, Richard, D.
77 Pond Avenue, Apt. 1106
Brookline, MA Massachusetts 02445 / US
07 / GUCKIAN, Kevin
44 Little Pond Road
Northborough, MA Massachusetts 01532 / US
08 / KUMARAVEL, Gnanasambandam
21 Appletree Lane
Lexington, MA Massachusetts 02420 / US
Representative(s)Miller, David James, et al
Mathys & Squire The Shard
32 London Bridge Street
London SE1 9SG / GB
[N/P]
Former [2017/14]Miller, David James, et al
Mathys & Squire LLP The Shard
32 London Bridge Street
London SE1 9SG / GB
Application number, filing date16183267.003.02.2012
[2017/14]
Priority number, dateUS201161440254P07.02.2011         Original published format: US 201161440254 P
[2017/14]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3150590
Date:05.04.2017
Language:EN
[2017/14]
Type: B1 Patent specification 
No.:EP3150590
Date:16.10.2019
Language:EN
[2019/42]
Search report(s)(Supplementary) European search report - dispatched on:EP04.01.2017
ClassificationIPC:C07D401/06, C07D405/12, C07D211/34, C07D211/60, C07D211/62, A61K31/55, A61P25/00
[2017/14]
CPC:
A61K31/445 (EP,IL,US); C07D401/06 (EP,CN,IL,KR,US); C07D211/62 (EP,CN,IL,US);
A61K31/225 (EP,IL,US); A61K31/4465 (EA); A61K31/4545 (EP,IL,US);
A61K31/4709 (EP,EA,IL,US); A61K31/498 (EP,IL,US); A61K31/517 (EP,IL,KR,US);
A61K31/55 (EP,IL,US); A61K31/695 (EP,IL,US); A61K38/21 (EP,IL,US);
A61K39/3955 (IL,US); A61P1/00 (EP); A61P1/04 (EP);
A61P11/06 (EP); A61P17/06 (EP); A61P19/02 (EP);
A61P21/00 (EP); A61P21/02 (EP); A61P25/00 (EP);
A61P25/02 (EP); A61P25/04 (EP); A61P25/14 (EP);
A61P25/16 (EP); A61P25/28 (EP,EA); A61P29/00 (EP);
A61P29/02 (EP); A61P3/10 (EP); A61P31/12 (EP);
A61P35/00 (EP); A61P35/04 (EP); A61P37/00 (EP);
A61P37/02 (EP); A61P37/06 (EP); A61P43/00 (EP);
A61P7/00 (EP); A61P9/00 (EP); A61P9/10 (EP);
C07D211/34 (EP,IL,US); C07D211/60 (EP,CN,IL,US); C07D215/20 (EP,IL,US);
C07D405/12 (EP,CN,IL,US); C07D471/04 (CN); C07F7/0812 (CN);
C07K16/2842 (IL,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/45]
Former [2017/14]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
Extension statesBA03.10.2017
ME03.10.2017
TitleGerman:S1P-MODULIERENDE MITTEL[2017/14]
English:S1P MODULATING AGENTS[2017/14]
French:AGENTS DE MODULATION S1P[2017/14]
Examination procedure08.08.2016Date on which the examining division has become responsible
03.10.2017Amendment by applicant (claims and/or description)
03.10.2017Examination requested  [2017/45]
11.04.2018Despatch of a communication from the examining division (Time limit: M06)
27.09.2018Reply to a communication from the examining division
29.10.2018Despatch of a communication from the examining division (Time limit: M02)
21.12.2018Reply to a communication from the examining division
10.04.2019Communication of intention to grant the patent
09.08.2019Fee for grant paid
09.08.2019Fee for publishing/printing paid
09.08.2019Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP12745253.0  / EP2672823
Divisional application(s)EP19203412.2  / EP3660010
Opposition(s)17.07.2020No opposition filed within time limit [2020/39]
Fees paidRenewal fee
08.08.2016Renewal fee patent year 03
08.08.2016Renewal fee patent year 04
08.08.2016Renewal fee patent year 05
27.02.2017Renewal fee patent year 06
07.02.2018Renewal fee patent year 07
26.02.2019Renewal fee patent year 08
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU03.02.2012
AL16.10.2019
AT16.10.2019
CY16.10.2019
CZ16.10.2019
DK16.10.2019
EE16.10.2019
FI16.10.2019
HR16.10.2019
LT16.10.2019
LV16.10.2019
MC16.10.2019
MK16.10.2019
MT16.10.2019
NL16.10.2019
PL16.10.2019
RO16.10.2019
RS16.10.2019
SE16.10.2019
SI16.10.2019
SK16.10.2019
SM16.10.2019
TR16.10.2019
BG16.01.2020
NO16.01.2020
GR17.01.2020
IE03.02.2020
LU03.02.2020
IS16.02.2020
PT17.02.2020
BE29.02.2020
CH29.02.2020
LI29.02.2020
[2022/32]
Former [2022/27]HU03.02.2012
AL16.10.2019
AT16.10.2019
CY16.10.2019
CZ16.10.2019
DK16.10.2019
EE16.10.2019
FI16.10.2019
HR16.10.2019
LT16.10.2019
LV16.10.2019
MC16.10.2019
MT16.10.2019
NL16.10.2019
PL16.10.2019
RO16.10.2019
RS16.10.2019
SE16.10.2019
SI16.10.2019
SK16.10.2019
SM16.10.2019
TR16.10.2019
BG16.01.2020
NO16.01.2020
GR17.01.2020
IE03.02.2020
LU03.02.2020
IS16.02.2020
PT17.02.2020
BE29.02.2020
CH29.02.2020
LI29.02.2020
Former [2021/12]AL16.10.2019
AT16.10.2019
CZ16.10.2019
DK16.10.2019
EE16.10.2019
FI16.10.2019
HR16.10.2019
LT16.10.2019
LV16.10.2019
MC16.10.2019
NL16.10.2019
PL16.10.2019
RO16.10.2019
RS16.10.2019
SE16.10.2019
SI16.10.2019
SK16.10.2019
SM16.10.2019
BG16.01.2020
NO16.01.2020
GR17.01.2020
IE03.02.2020
LU03.02.2020
IS16.02.2020
PT17.02.2020
BE29.02.2020
CH29.02.2020
LI29.02.2020
Former [2021/08]AL16.10.2019
AT16.10.2019
CZ16.10.2019
DK16.10.2019
EE16.10.2019
FI16.10.2019
HR16.10.2019
LT16.10.2019
LV16.10.2019
MC16.10.2019
NL16.10.2019
PL16.10.2019
RO16.10.2019
RS16.10.2019
SE16.10.2019
SI16.10.2019
SK16.10.2019
SM16.10.2019
BG16.01.2020
NO16.01.2020
GR17.01.2020
IE03.02.2020
LU03.02.2020
IS16.02.2020
PT17.02.2020
CH29.02.2020
LI29.02.2020
Former [2020/51]AL16.10.2019
AT16.10.2019
CZ16.10.2019
DK16.10.2019
EE16.10.2019
FI16.10.2019
HR16.10.2019
LT16.10.2019
LV16.10.2019
MC16.10.2019
NL16.10.2019
PL16.10.2019
RO16.10.2019
RS16.10.2019
SE16.10.2019
SI16.10.2019
SK16.10.2019
SM16.10.2019
BG16.01.2020
NO16.01.2020
GR17.01.2020
LU03.02.2020
IS16.02.2020
PT17.02.2020
CH29.02.2020
LI29.02.2020
Former [2020/50]AL16.10.2019
AT16.10.2019
CZ16.10.2019
DK16.10.2019
EE16.10.2019
FI16.10.2019
HR16.10.2019
LT16.10.2019
LV16.10.2019
MC16.10.2019
NL16.10.2019
PL16.10.2019
RO16.10.2019
RS16.10.2019
SE16.10.2019
SI16.10.2019
SK16.10.2019
SM16.10.2019
BG16.01.2020
NO16.01.2020
GR17.01.2020
LU03.02.2020
IS16.02.2020
PT17.02.2020
Former [2020/48]AL16.10.2019
AT16.10.2019
CZ16.10.2019
DK16.10.2019
EE16.10.2019
FI16.10.2019
HR16.10.2019
LT16.10.2019
LV16.10.2019
NL16.10.2019
PL16.10.2019
RO16.10.2019
RS16.10.2019
SE16.10.2019
SK16.10.2019
SM16.10.2019
BG16.01.2020
NO16.01.2020
GR17.01.2020
LU03.02.2020
IS16.02.2020
PT17.02.2020
Former [2020/37]AL16.10.2019
AT16.10.2019
CZ16.10.2019
DK16.10.2019
EE16.10.2019
FI16.10.2019
HR16.10.2019
LT16.10.2019
LV16.10.2019
NL16.10.2019
PL16.10.2019
RO16.10.2019
RS16.10.2019
SE16.10.2019
SK16.10.2019
SM16.10.2019
BG16.01.2020
NO16.01.2020
GR17.01.2020
IS16.02.2020
PT17.02.2020
Former [2020/36]AL16.10.2019
AT16.10.2019
CZ16.10.2019
DK16.10.2019
EE16.10.2019
FI16.10.2019
HR16.10.2019
LT16.10.2019
LV16.10.2019
NL16.10.2019
PL16.10.2019
RO16.10.2019
RS16.10.2019
SE16.10.2019
BG16.01.2020
NO16.01.2020
GR17.01.2020
IS16.02.2020
PT17.02.2020
Former [2020/35]AL16.10.2019
AT16.10.2019
CZ16.10.2019
FI16.10.2019
HR16.10.2019
LT16.10.2019
LV16.10.2019
NL16.10.2019
PL16.10.2019
RO16.10.2019
RS16.10.2019
SE16.10.2019
BG16.01.2020
NO16.01.2020
GR17.01.2020
PT17.02.2020
IS24.02.2020
Former [2020/32]AL16.10.2019
AT16.10.2019
FI16.10.2019
HR16.10.2019
LT16.10.2019
LV16.10.2019
NL16.10.2019
PL16.10.2019
RS16.10.2019
SE16.10.2019
BG16.01.2020
NO16.01.2020
GR17.01.2020
PT17.02.2020
IS24.02.2020
Former [2020/25]AT16.10.2019
FI16.10.2019
HR16.10.2019
LT16.10.2019
LV16.10.2019
NL16.10.2019
PL16.10.2019
RS16.10.2019
SE16.10.2019
BG16.01.2020
NO16.01.2020
GR17.01.2020
PT17.02.2020
IS24.02.2020
Former [2020/24]AT16.10.2019
FI16.10.2019
LT16.10.2019
LV16.10.2019
NL16.10.2019
PL16.10.2019
SE16.10.2019
BG16.01.2020
NO16.01.2020
GR17.01.2020
PT17.02.2020
IS24.02.2020
Former [2020/23]AT16.10.2019
FI16.10.2019
LT16.10.2019
LV16.10.2019
NL16.10.2019
PL16.10.2019
SE16.10.2019
BG16.01.2020
NO16.01.2020
GR17.01.2020
PT17.02.2020
Former [2020/22]FI16.10.2019
LT16.10.2019
NL16.10.2019
SE16.10.2019
BG16.01.2020
NO16.01.2020
PT17.02.2020
Former [2020/21]NL16.10.2019
NO16.01.2020
Former [2020/20]NL16.10.2019
Documents cited:Search[A]US2008027036  (BURLI ROLAND [US], et al) [A] 1-18 * Abstract; claims; examples. *;
 [Y]US2010160258  (CALDWELL RICHARD D [US], et al) [Y] 1-18 * Abstract; claims. *;
 [Y]US2010160357  (CALDWELL RICHARD D [US], et al) [Y] 1-18* Abstract; claims. *;
 [Y]US7750021  (MI YUAN [CN], et al) [Y] 1-18 * Column 1, lines 19-30; column 1, line 53 to column 2, line 37, in particular the definition of R1; column 4, lines 24-60; examples e.g. columns 59-60, compound 118. *;
 [XPI]WO2011017561  (BIOGEN IDEC INC [US], et al) [XP] 1-11,13-18 * Abstract; claims; examples e.g. pages 35-36, examples 24-25, pages 42-44, examples 39-42. * [I] 12;
 [A]  - MARSOLAIS, ROSEN, "Chemical modulators of sphingosine-1-phosphate receptors as barrier-oriented therapeutic molecules", NATURE REVIEWS DRUG DISCOVERY, (20090320), vol. 8, no. 4, doi:10.1038/NRD2356, ISSN 1474-1784, pages 297 - 307, XP002617578 [A] 1-18 * the whole document *

DOI:   http://dx.doi.org/10.1038/NRD2356
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    - DAVIS ET AL., JOURNAL OF BIOLOGICAL CHEMISTRY, (2005), vol. 280, pages 9833 - 9841
 WO2012US23799
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