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Extract from the Register of European Patents

EP About this file: EP3245299

EP3245299 - USING SIZE AND NUMBER ABERRATIONS IN PLASMA DNA FOR DETECTING CANCER [Right-click to bookmark this link]
Status	Grant of patent is intended Status updated on 18.02.2024 Database last updated on 14.06.2024
Former	Examination is in progress Status updated on 24.04.2019
Former	Request for examination was made Status updated on 20.10.2017
Former	The international publication has been made Status updated on 12.07.2017
Most recent event Tooltip	18.02.2024	New entry: Communication of intention to grant a patent
Applicant(s)	For all designated states The Chinese University of Hong Kong Office of Research and Knowledge Transfer Services Room 301, Pi Ch'iu Building Shatin, New Territories Hong Kong 999077 / HK
	[2024/11]
Former [2017/47]	For all designated states The Chinese University Of Hong Kong Office of Research and Knowledge Transfer Services (ORKTS) Room 301Pi Ch'iu Building Shatin, New Territories Hong Kong 999077 / CN
Inventor(s)	01 / LO, Yuk-Ming Dennis 4th Floor 7 King Tak Street Homantim Kowloon Hong Kong 999077 / HK
	02 / CHIU, Rossa Wai Kwun House 31 Double Haven 52 Ma Lok Path Shatin New Territories Hong Kong 999077 / HK
	03 / CHAN, Kwan Chee Flat C 15th Floor Block 5 Peak One Mei Tin Road, Shatin, New Territories Hong Kong 999077 / HK
	04 / JIANG, Peiyong Flat 7 on 1st Floor of Block B of Kwong Lam Court Nos. 62-66 (No.62) Siu Lek Yuen Road Shatin New Territories Hong Kong 999077 / HK
	[2024/10]
Former [2017/47]	01 / LO, Yuk-Ming Dennis 4th Floor 7 King Tak Street Homantim Kowloon Hong Kong 999077 / CN
	02 / CHIU, Rossa Wai Kwun House 31 Double Haven 52 Ma Lok Path Shatin New Territories Hong Kong 999077 / CN
	03 / CHAN, Kwan Chee Flat C 15th Floor Block 5 Peak One Mei Tin Road, Shatin, New Territories Hong Kong 999077 / CN
	04 / JIANG, Peiyong Flat 7 on 1st Floor of Block B of Kwong Lam Court Nos. 62-66 (No.62) Siu Lek Yuen Road Shatin New Territories Hong Kong 999077 / CN
Representative(s)	J A Kemp LLP 80 Turnmill Street London EC1M 5QU / GB
	[N/P]
Former [2017/47]	J A Kemp 14 South Square Gray's Inn London WC1R 5JJ / GB
Application number, filing date	16737075.8	13.01.2016
	[2017/47]
	WO2016CN70785
Priority number, date	US201562102867P	13.01.2015 Original published format: US 201562102867 P
	US201562111534P	03.02.2015 Original published format: US 201562111534 P
	[2017/47]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO2016112850
	Date:	21.07.2016
	Language:	EN
	[2016/29]
	Type:	A1 Application with search report
	No.:	EP3245299
	Date:	22.11.2017
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 21.07.2016 takes the place of the publication of the European patent application.
	[2017/47]
Search report(s)	International search report - published on:	CN	21.07.2016
	(Supplementary) European search report - dispatched on:	EP	04.06.2018
Classification	IPC:	C12Q1/6886, C12Q1/6869, G16B20/10, G16B40/30	[2024/10]
	CPC:	C12Q1/6886 (EP,CN,KR,US); G16B40/00 (EP,CN,KR,US); C12Q1/6869 (EP,CN,KR,US); G16B20/00 (EP,CN,KR,US); G16B20/10 (EP,US); G16B20/20 (EP,US); (+) G16B40/30 (EP,US); C12Q2535/122 (KR); C12Q2600/112 (EP,CN,KR,US); C12Q2600/156 (EP,CN,KR,US) (-)
	C-Set:	C12Q1/6869, C12Q2535/122, C12Q2537/16 (EP,US); C12Q1/6869, C12Q2537/16, C12Q2535/122, C12Q2545/113 (CN)
	Former IPC [2018/27]	C12Q1/6886, C12Q1/6869, G06F19/24
	Former IPC [2017/47]	C12Q1/68
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2017/47]
Title	German:	VERWENDUNG VON GRÖSSEN- UND ZAHLABERRATIONEN IN PLASMA-DNA ZUM NACHWEIS VON KREBS	[2017/47]
	English:	USING SIZE AND NUMBER ABERRATIONS IN PLASMA DNA FOR DETECTING CANCER	[2017/47]
	French:	UTILISATION DES ABERRATIONS EN TAILLE ET NOMBRE DANS L'ADN PLASMATIQUE POUR DÉPISTER LE CANCER	[2017/47]
Entry into regional phase	11.07.2017	National basic fee paid
	11.07.2017	Search fee paid
	11.07.2017	Designation fee(s) paid
	11.07.2017	Examination fee paid
Examination procedure	11.07.2017	Examination requested [2017/47]
	11.07.2017	Date on which the examining division has become responsible
	18.12.2018	Amendment by applicant (claims and/or description)
	29.04.2019	Despatch of a communication from the examining division (Time limit: M06)
	22.10.2019	Reply to a communication from the examining division
	24.04.2020	Despatch of a communication from the examining division (Time limit: M06)
	26.10.2020	Reply to a communication from the examining division
	23.09.2021	Despatch of a communication from the examining division (Time limit: M04)
	25.01.2022	Reply to a communication from the examining division
	18.01.2024	Cancellation of oral proceeding that was planned for 26.01.2024
	26.01.2024	Date of oral proceedings (cancelled)
	19.02.2024	Communication of intention to grant the patent
Fees paid	Renewal fee
	15.01.2018	Renewal fee patent year 03
	15.01.2019	Renewal fee patent year 04
	14.01.2020	Renewal fee patent year 05
	13.01.2021	Renewal fee patent year 06
	16.12.2021	Renewal fee patent year 07
	14.12.2022	Renewal fee patent year 08
	14.12.2023	Renewal fee patent year 09
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[A]JP2002272497 (VENTURE LINK CO LTD, et al) [A] 1-15* the whole document *;
		[XYI]WO2009051842 (UNIV JOHNS HOPKINS [US], et al) [X] 1,3,15 * p. 1, l. 27-30; p. 2, l. 7-16; p. 2, l. 25 - p. 3, l. 7; p. 6, l. 17-32 * [Y] 4,5 [I] 2,6-14;
		[A]US2013040824 (LO YUK MING DENNIS [HK], et al) [A] 1-15 * the whole document *;
		[Y]US2013237431 (LO YUK MING DENNIS [CN], et al) [Y] 4,5 * para. 155-159 *;
		[E]WO2016116033 (UNIV HONG KONG CHINESE [CN]) [E] 1-15 * para. 4; claim 1 *;
		[XYI] - S. C. Y. YU ET AL, "Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, US, (20140519), vol. 111, no. 23, doi:10.1073/pnas.1406103111, ISSN 0027-8424, pages 8583 - 8588, XP055297276 [X] 1-3,8-10,12,13,15 * abstract; p. 8584, left-hand col., 5th para.; p. 8585, left-hand col., last para. - p. 8586, left-hand col., 4th para.; p. 8587, left-hand col., last para. - right-hand col., 1st para.; p. 8587, right-hand col., last para.; p. 8588, left-hand col., 1st-2nd para.; p. 8588, right-hand col., last para.; Supplementary information: table S1 * [Y] 4,5 [I] 6,7,11,14 DOI: http://dx.doi.org/10.1073/pnas.1406103111
		[IP] - PEIYONG JIANG ET AL, "Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, US, (20150202), vol. 112, no. 11, doi:10.1073/pnas.1500076112, ISSN 0027-8424, pages E1317 - E1325, XP055223840 [IP] 1-15 * abstract; fig. 1; p. e1319; p. e1324, left-hand col., 3d para. * DOI: http://dx.doi.org/10.1073/pnas.1500076112
	International search	[A]WO2014039556 (GUARDANT HEALTH INC [US], et al) [A] 1-39* See the whole document, especially the abstract *;
		[A]US2014080715 (LO YUK-MING DENNIS [CN], et al) [A] 1-39 * See the whole document, especially the abstract *
	by applicant	WO2019051842

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