EP3356367 - FUSED PYRAZOLE DERIVATIVES AS KINASE INHIBITORS [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 26.06.2020 Database last updated on 03.08.2024 | |
Former | Examination is in progress Status updated on 19.07.2019 | ||
Former | Request for examination was made Status updated on 06.07.2018 | ||
Former | The international publication has been made Status updated on 08.04.2017 | Most recent event Tooltip | 26.06.2020 | Application deemed to be withdrawn | published on 29.07.2020 [2020/31] | Applicant(s) | For all designated states UCB Biopharma SRL Allée de la Recherche 60 1070 Brussels / BE | For all designated states Katholieke Universiteit Leuven K.U. Leuven R&D Waaistraat 6 3000 Leuven / BE | [N/P] |
Former [2020/02] | For all designated states UCB Biopharma SRL Allé de la Recherche 60 1070 Brussels / BE | ||
For all designated states Katholieke Universiteit Leuven K.U. Leuven R&D Waaistraat 6 3000 Leuven / BE | |||
Former [2018/32] | For all designated states UCB Biopharma SPRL 60, Allée de la Recherche 1070 Brussels / BE | ||
For all designated states Katholieke Universiteit Leuven K.U. Leuven R&D Waaistraat 6 3000 Leuven / BE | Inventor(s) | 01 /
FORD, Daniel James c/o IPD UCB Celltech 208 Bath Road Slough Berkshire SL1 3WE / GB | 02 /
HORSLEY, Helen Tracey c/o IPD UCB Celltech 208 Bath Road Slough Berkshire SL1 3WE / GB | 03 /
REUBERSON, James Thomas c/o IPD UCB Celltech 208 Bath Road Slough Berkshire SL1 3WE / GB | [2018/32] | Representative(s) | UCB Intellectual Property c/o UCB Celltech IP Department 208 Bath Road Slough, Berkshire SL1 3WE / GB | [2018/32] | Application number, filing date | 16770942.7 | 28.09.2016 | [2018/32] | WO2016EP73028 | Priority number, date | GB20150017263 | 30.09.2015 Original published format: GB 201517263 | [2018/32] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2017055305 | Date: | 06.04.2017 | Language: | EN | [2017/14] | Type: | A1 Application with search report | No.: | EP3356367 | Date: | 08.08.2018 | Language: | EN | The application published by WIPO in one of the EPO official languages on 06.04.2017 takes the place of the publication of the European patent application. | [2018/32] | Search report(s) | International search report - published on: | EP | 06.04.2017 | Classification | IPC: | C07D487/04, C07D491/107, C07D491/08, C07D498/04, C07D451/06, A61K31/519, A61K31/53, A61P29/00, A61P35/00, A61P31/00, A61P33/00, A61K31/5377, A61K31/5386 | [2018/32] | CPC: |
C07D487/04 (EP,US);
A61P29/00 (EP);
A61P31/00 (EP);
A61P31/12 (EP);
A61P33/00 (EP);
A61P33/06 (EP);
A61P35/00 (EP);
A61P37/06 (EP);
C07D451/06 (EP,US);
C07D491/08 (EP,US);
C07D491/107 (EP,US);
C07D498/04 (EP,US);
Y02A50/30 (EP)
(-)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2018/32] | Title | German: | KONDENSIERTE PYRAZOLDERIVATE ALS KINASEINHIBITOREN | [2018/32] | English: | FUSED PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | [2018/32] | French: | DÉRIVÉS DE PYRAZOLE CONDENSÉS EN TANT QU'INHIBITEURS DE KINASE | [2018/32] | Entry into regional phase | 30.04.2018 | National basic fee paid | 30.04.2018 | Designation fee(s) paid | 30.04.2018 | Examination fee paid | Examination procedure | 22.03.2018 | Date on which the examining division has become responsible | 30.04.2018 | Examination requested [2018/32] | 22.11.2018 | Amendment by applicant (claims and/or description) | 24.07.2019 | Despatch of a communication from the examining division (Time limit: M04) | 04.12.2019 | Application deemed to be withdrawn, date of legal effect [2020/31] | 13.01.2020 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2020/31] | Fees paid | Renewal fee | 01.10.2018 | Renewal fee patent year 03 | 30.09.2019 | Renewal fee patent year 04 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [X]WO2004022561 (SCHERING CORP [US], et al) [X] 1-4,7-11 * inter alia the compounds of examples 268-275, 342, 343, 350-354, 369, 378-384, 385-387, 398, 401, 402, 405 and 411;; claims 1, 36, 40 *; | [X]WO2004081013 (TEIJIN PHARMA LTD [JP], et al) [X] 1-5,7-11 * claims 1, 10; compounds 72, 81, 82, 95 *; | [X]US2007082900 (GUZI TIMOTHY J [US], et al) [X] 1-5,7-11 * paragraph [0002]; claim 1; compounds 130-C *; | [X]US2007225270 (GUZI TIMOTHY J [US], et al) [X] 1-5,7-11 * twenty-five compounds of claim 1, in particular on pages 426 (two compounds), 427 (two compounds), 428 (five compounds), 429 (eleven compounds), 430 (four compounds) and 431 (one compound);; claims 1, 3, 9 *; | [X]WO2012027234 (SCHERING CORP [US], et al) [X] 1-5 * the starting material of step 4 on page 58 *; | [AD]WO2014096423 (UCB PHARMA SA [BE], et al) [AD] 1-11 * claims 1, 15, 16 *; | [A]WO2015086512 (UCB BIOPHARMA SPRL [BE]) [A] 1-11 * claims 1, 13, 16 *; | [XDP]WO2015193169 (UCB BIOPHARMA SPRL [BE], et al) [XDP] 1,2,4,5,7-11* claims 1, 5, 6, 15-17 *; | [X] - HONGYI YU ET AL, "[3 a ,4]-Dihydropyrazolo[1,5 a ]pyrimidines: Novel, Potent, and Selective Phosphatidylinositol-3-kinase [beta] Inhibitors", ACS MEDICINAL CHEMISTRY LETTERS, United States, (20130214), vol. 4, no. 2, doi:10.1021/ml300330m, ISSN 1948-5875, pages 230 - 234, XP055315541 [X] 1-4,7-11 * compounds 4a, 4b, 5b-5d, 6c, 7a-7l * DOI: http://dx.doi.org/10.1021/ml300330m | [A] - IVANA MEJDROVÁ ET AL, "Highly Selective Phosphatidylinositol 4-Kinase III[beta] Inhibitors and Structural Insight into Their Mode of Action", JOURNAL OF MEDICINAL CHEMISTRY, (20150514), vol. 58, no. 9, doi:10.1021/acs.jmedchem.5b00499, ISSN 0022-2623, pages 3767 - 3793, XP055206384 [A] 1-11 * tables 1, 2; compounds 1, 2a-2l, 3-15 * DOI: http://dx.doi.org/10.1021/acs.jmedchem.5b00499 | [A] - M. ARITA ET AL, "Phosphatidylinositol 4-Kinase III Beta Is a Target of Enviroxime-Like Compounds for Antipoliovirus Activity", JOURNAL OF VIROLOGY, (20101222), vol. 85, no. 5, doi:10.1128/JVI.02249-10, ISSN 0022-538X, pages 2364 - 2372, XP055111280 [A] 1-11 * compound T-00127-HEV1;; figure 1; table 1 * DOI: http://dx.doi.org/10.1128/JVI.02249-10 | by applicant | WO2010103130 | WO2011147753 | WO2012035423 | WO2013024291 | WO2013034738 | WO2013068458 | WO2014053581 | WO2014096423 | WO2015193167 | WO2015193168 | WO2015193169 | - C.W. MCNAMARA ET AL., NATURE, (2013), vol. 504, pages 248 - 253 | - I. MEJDROVA ET AL., J. MED. CHEM., (2015), vol. 58, pages 3767 - 3793 | - A.M. MACLEOD ET AL., ACS MED. CHEM. LETT., (2013), vol. 4, pages 585 - 589 | - M. ARITA ET AL., J. VIRAL., (2011), vol. 85, pages 2364 - 2372 |