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Extract from the Register of European Patents

EP About this file: EP3319970

EP3319970 - PYRIDO-OXAZINONE DERIVATIVES AS TNAP INHIBITORS [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 10.07.2020 Database last updated on 03.09.2024
Former	The patent has been granted Status updated on 26.07.2019
Former	Grant of patent is intended Status updated on 12.03.2019
Former	Request for examination was made Status updated on 13.04.2018
Former	The international publication has been made Status updated on 13.01.2017
Former	unknown Status updated on 11.11.2016
Most recent event Tooltip	14.08.2020	Change - lapse in a contracting state State(s) deleted from list of lapses: IS	published on 16.09.2020 [2020/38]
Applicant(s)	For all designated states Daiichi Sankyo Company, Limited 3-5-1, Nihonbashi Honcho Chuo-ku Tokyo 103-8426 / JP
	For all designated states Sanford Burnham Prebys Medical Discovery Institute 10901 N. Torrey Pines Rd. La Jolla, CA 92037 / US
	[2019/15]
Former [2018/20]	For all designated states Daiichi Sankyo Company, Limited 3-5-1 Nihonbashi-honcho Chuo-ku Tokyo 103-8426 / JP
	For all designated states Sanford Burnham Prebys Medical Discovery Institute 10901 N. Torrey Pines Rd. La Jolla, CA 92037 / US
Inventor(s)	01 / MIYAZAKI, Shojiro c/o Daiichi Sankyo Company Limited 1-2-58 Hiromachi Shinagawa-ku Tokyo 140-8710 / JP
	02 / YAMAMOTO, Yuko c/o Daiichi Sankyo Company Limited 1-2-58 Hiromachi Shinagawa-ku Tokyo 140-8710 / JP
	03 / SUZUKI, Keisuke c/o Daiichi Sankyo Company Limited 1-2-58 Hiromachi Shinagawa-ku Tokyo 140-8710 / JP
	04 / INUI, Masaharu c/o Daiichi Sankyo Company Limited 1-2-58 Hiromachi Shinagawa-ku Tokyo 140-8710 / JP
	05 / IZUMI, Masanori c/o Daiichi Sankyo Company Limited 1-2-58 Hiromachi Shinagawa-ku Tokyo 140-8710 / JP
	06 / SOMA, Kaori c/o Daiichi Sankyo Company Limited 1-2-58 Hiromachi Shinagawa-ku Tokyo 140-8710 / JP
	07 / PINKERTON, Anthony c/o Sanford Burnham Prebys Medical Discovery Institute 10901 North Torrey Pines Road La Jolla, CA 92037 / US
	08 / SHINOZAKI, Taeko c/o Daiichi Sankyo Company Limited 1-2-58 Hiromachi Shinagawa-ku Tokyo 140-8710 / JP
	[2018/20]
Representative(s)	Wallace, Sheila Jane Marks & Clerk LLP 15 Fetter Lane London EC4A 1BW / GB
	[2019/35]
Former [2018/20]	Wallace, Sheila Jane Marks & Clerk LLP 90 Long Acre London WC2E 9RA / GB
Application number, filing date	16775006.6	07.07.2016
	[2018/20]
	WO2016US41345
Priority number, date	US201562190145P	08.07.2015 Original published format: US 201562190145 P
	[2018/20]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO2017007943
	Date:	12.01.2017
	Language:	EN
	[2017/02]
	Type:	A1 Application with search report
	No.:	EP3319970
	Date:	16.05.2018
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 12.01.2017 takes the place of the publication of the European patent application.
	[2018/20]
	Type:	B1 Patent specification
	No.:	EP3319970
	Date:	28.08.2019
	Language:	EN
	[2019/35]
Search report(s)	International search report - published on:	EP	12.01.2017
Classification	IPC:	C07D498/04, A61K31/4353, A61P19/00	[2018/20]
	CPC:	C07D498/10 (EP,KR,RU,US); C07D498/04 (EP,IL,KR,RU,US); A61K31/553 (EP,KR,RU,US); A61K9/20 (KR,US); A61K9/48 (KR,US); A61P19/00 (EP,KR,RU); (+) A61P19/02 (EP); A61P19/04 (EP); A61P35/00 (EP); A61P43/00 (EP); A61P9/00 (EP); A61P9/14 (EP) (-)
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2018/20]
Extension states	BA	Not yet paid
	ME	Not yet paid
Validation states	MA	Not yet paid
	MD	Not yet paid
Title	German:	PYRIDO-OXAZINONDERIVATE ALS TNAP-INHIBITOREN	[2018/20]
	English:	PYRIDO-OXAZINONE DERIVATIVES AS TNAP INHIBITORS	[2018/20]
	French:	DÉRIVÉS DE PYRIDO-OXAZINONE UTILISÉ COMME INHIBITEURS DE TNAP	[2018/20]
Entry into regional phase	18.12.2017	National basic fee paid
	18.12.2017	Designation fee(s) paid
	18.12.2017	Examination fee paid
Examination procedure	18.12.2017	Examination requested [2018/20]
	18.12.2017	Date on which the examining division has become responsible
	01.10.2018	Amendment by applicant (claims and/or description)
	13.03.2019	Communication of intention to grant the patent
	18.07.2019	Fee for grant paid
	18.07.2019	Fee for publishing/printing paid
	18.07.2019	Receipt of the translation of the claim(s)
Opposition(s)	03.06.2020	No opposition filed within time limit [2020/33]
Fees paid	Renewal fee
	11.07.2018	Renewal fee patent year 03
	15.07.2019	Renewal fee patent year 04
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	deleted
	[2020/38]
Former [2020/14]	IS	28.12.2019
Cited in	International search	[AD]WO2013126608 (SANFORD BURNHAM MED RES INST [US]) [AD] 1-22 * pages 1-2; example - *;
		[AD] - DEBRAY JULIEN ET AL, "Inhibitors of tissue-nonspecific alkaline phosphatase: Design, synthesis, kinetics, biomineralization and cellular tests", BIOORGANIC & MEDICINAL CHEMISTRY, (2013), vol. 21, no. 24, doi:10.1016/J.BMC.2013.09.053, ISSN 0968-0896, pages 7981 - 7987, XP028796465 [AD] 1-22 * the whole document * DOI: http://dx.doi.org/10.1016/j.bmc.2013.09.053
	by applicant	WO2009017863
		WO2013126608
		US2015011551
		- J. BONE MINER RES, (2006), vol. 24, pages 176 - 181
		- CLIN. KIDERY. J., (2014), vol. 7, pages 167 - 173
		- EUR. HEART. J., (2014), vol. 35, pages 1515 - 1525
		- INT. J. NEPHROL. RENOVASC. DIS., (2014), vol. 7, pages 161 - 168
		- J. HISTOCHEM. CYTOCHEM., (2002), vol. 50, pages 333 - 340
		- J. AM. SOC. NEPHROL., (2004), vol. 15, pages 1392 - 1401
		- J. BONE MINER RES, (2013), vol. 7, pages 1587 - 1598
		- J. BONE MINER RES, (2007), vol. 22, pages 1700 - 1710
		- BIOORG. MED. CHEM. LETT., (2009), vol. 19, pages 222 - 225
		- J. MED. CHEM., (2009), vol. 52, pages 6919 - 6925
		- BIOORG. MED. CHEM., (2013), vol. 21, pages 7981 - 7897
		- J.BONE MINER RES, (2015), vol. 30, pages 824 - 836
		- Comprehensive Organic Transformations, Second Edition,, JOHN WILEY SONS, INC., (1999), pages 1978 - 1982
		- Comprehensive Organic Transformations, Fourth Edition,, JOHN WILEY SONS, INC., (1999), pages 821 - 828
		- A. P. DISHINGTON; P. D. JOHNSON; J. G. KETTLE, Tetrahedron Letters, (2004), vol. 45, page 3733
		- S. BHAGWANTH; A. G. WATERSON; G. M. ADJABENG; K. R. HORNBERGER, JOURNAL OF ORGANIC CHEMISTRY, (2009), vol. 74, page 4634
		- P. G. M. WUTS, Protective Groups in Organic Synthesis, Fourth Edition, JOHN WILEY SONS, INC., (2007), pages 725 - 735
		- X. WANG; A. GURAM; M. RONK; J. E. MILNE; J. S. TEDROW; M. M. FAUL, Tetrahedron Letters, (2012), vol. 53, page 7
		- W. DENG; L. LIU; C. ZHANG; M. LIU; Q.-X. GUO, TETRAHEDRON LETTERS, (2005), vol. 46, page 7295
		- D. K. LUCI; J. B. JAMESON; A. YASGAR; G. DIAZ; N. JOSHI; A. KANTZ; K. MARKHAM; S. PERRY; N. KUHN; J. YEUNG, JOURNAL OF MEDICINAL CHEMISTRY, (2014), vol. 57, page 495

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