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Extract from the Register of European Patents

EP About this file: EP3383899

EP3383899 - MULTISPECIFIC ANTIBODIES [Right-click to bookmark this link]
StatusThe application has been refused
Status updated on  07.04.2023
Database last updated on 28.09.2024
FormerExamination is in progress
Status updated on  29.07.2019
FormerRequest for examination was made
Status updated on  07.09.2018
FormerThe international publication has been made
Status updated on  15.06.2017
Formerunknown
Status updated on  13.12.2016
Most recent event   Tooltip07.04.2023Refusal of applicationpublished on 10.05.2023  [2023/19]
Applicant(s)For all designated states
UCB Biopharma SRL
Allée de la Recherche 60
1070 Brussels / BE
[N/P]
Former [2020/02]For all designated states
UCB Biopharma SRL
Allé de la Recherche 60
1070 Brussels / BE
Former [2018/41]For all designated states
UCB Biopharma SPRL
60, Allée de la Recherche
1070 Brussels / BE
Inventor(s)01 / WRIGHT, Michael John
c/o IPD
UCB Celltech
208 Bath Road
Slough Berkshire SL1 3WE / GB
 [2018/41]
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[N/P]
Former [2018/41]UCB Intellectual Property
c/o UCB Celltech
IP Department
208 Bath Road
Slough, Berkshire SL1 3WE / GB
Application number, filing date16805400.501.12.2016
[2018/41]
WO2016EP79435
Priority number, dateGB2015002139303.12.2015         Original published format: GB 201521393
[2018/41]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017093406
Date:08.06.2017
Language:EN
[2017/23]
Type: A1 Application with search report 
No.:EP3383899
Date:10.10.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 08.06.2017 takes the place of the publication of the European patent application.
[2018/41]
Search report(s)International search report - published on:EP08.06.2017
ClassificationIPC:C07K16/00, C07K16/14, C07K16/46, C07K14/39
[2018/41]
CPC:
C07K16/468 (EP,US); A61P43/00 (EP); C07K14/39 (EP,US);
C07K16/00 (EP,US); C07K16/14 (EP,US); C07K2317/31 (US);
C07K2317/34 (US); C07K2317/55 (US); C07K2317/622 (US);
C07K2319/00 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/41]
TitleGerman:MULTISPEZIFISCHE ANTIKÖRPER[2018/41]
English:MULTISPECIFIC ANTIBODIES[2018/41]
French:ANTICORPS MULTISPÉCIFIQUES[2018/41]
Entry into regional phase03.07.2018National basic fee paid 
03.07.2018Designation fee(s) paid 
03.07.2018Examination fee paid 
Examination procedure19.06.2018Date on which the examining division has become responsible
03.07.2018Examination requested  [2018/41]
10.01.2019Amendment by applicant (claims and/or description)
01.08.2019Despatch of a communication from the examining division (Time limit: M06)
27.01.2020Reply to a communication from the examining division
06.12.2022Cancellation of oral proceeding that was planned for 09.12.2022
09.12.2022Date of oral proceedings (cancelled)
20.12.2022Despatch of communication that the application is refused, reason: substantive examination [2023/19]
30.12.2022Application refused, date of legal effect [2023/19]
Fees paidRenewal fee
02.01.2019Renewal fee patent year 03
02.01.2020Renewal fee patent year 04
11.01.2021Renewal fee patent year 05
03.01.2022Renewal fee patent year 06
02.01.2023Renewal fee patent year 07
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Cited inInternational search[Y]WO9311162  (PROTEIN DESIGN LABS INC [US]) [Y] 1-43 * page 3, lines 3-5 * * page 3, lines 21-23 * * figure 5 *;
 [Y]WO03012069  (ABMAXIS INC [US], et al) [Y] 1-43 * claims 1,4,5,10,11,17 * * figures 12-18 *;
 [Y]WO2012116453  (ZYMEWORKS INC [CA], et al) [Y] 1-43 * paragraph [0012] * * paragraph [0013] * * examples 3,6,7 *;
 [Y]WO2014001326  (HOFFMANN LA ROCHE [CH], et al) [Y] 1-43 * page 6, line 25 - page 7, line 7 * * claims 1,16 * * example 13 * * figure 1 *;
 [XP]WO2015181282  (UCB BIOPHARMA SPRL [BE]) [XP] 1-43* the whole document *;
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DOI:   http://dx.doi.org/10.1038/leu.2013.243
 [Y]  - D. M. GOLDENBERG ET AL, "Multifunctional Antibodies by the Dock-and-Lock Method for Improved Cancer Imaging and Therapy by Pretargeting", THE JOURNAL OF NUCLEAR MEDICINE, (20080101), vol. 49, no. 1, doi:10.2967/jnumed.107.046185, ISSN 0161-5505, pages 158 - 163, XP055028152 [Y] 1-43 * abstract * * figure 1 * * figure 2 *

DOI:   http://dx.doi.org/10.2967/jnumed.107.046185
 [Y]  - HAIMING LUO ET AL, "Design and Applications of Bispecific Heterodimers: Molecular Imaging and beyond", MOLECULAR PHARMACEUTICS, (20140602), vol. 11, no. 6, doi:10.1021/mp500115x, ISSN 1543-8384, pages 1750 - 1761, XP055204892 [Y] 1-43 * page 1753, column l, paragraph 4 - page 1754, column r, paragraph 2 *

DOI:   http://dx.doi.org/10.1021/mp500115x
 [Y]  - ZAHND CHRISTIAN ET AL, "Directed in vitro evolution and crystallographic analysis of a peptide-binding single chain antibody fragment (scFv) with low picomolar affinity", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, (20040430), vol. 279, no. 18, doi:10.1074/JBC.M309169200, ISSN 0021-9258, pages 18870 - 18877, XP002406477 [Y] 1-43 * the whole document *

DOI:   http://dx.doi.org/10.1074/jbc.M309169200
 [Y]  - HANES JOZEF ET AL, "Ribosome display efficiently selects and evolves high-affinity antibodies in vitro from immune libraries", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, US, (19981124), vol. 95, no. 24, doi:10.1073/PNAS.95.24.14130, ISSN 0027-8424, pages 14130 - 14135, XP002165663 [Y] 1-43 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.95.24.14130
 [A]  - ROLAND KONTERMANN, "Dual targeting strategies with bispecific antibodies", MABS, LANDES BIOSCIENCE, US, (20120301), vol. 4, no. 2, doi:10.4161/MABS.4.2.19000, ISSN 1942-0870, pages 182 - 197, XP009160769 [A] 1-43 * the whole document * * figure 2 *

DOI:   http://dx.doi.org/10.4161/mabs.4.2.19000
 [A]  - KO SANGHWAN ET AL, "Engineering antibodies for dual specificity and enhanced potency", BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, KOREAN SOCIETY FOR BIOTECHNOLOGY AND BIOENGINEERING, SEOUL, KR, vol. 20, no. 2, doi:10.1007/S12257-014-0575-6, ISSN 1226-8372, (20150519), pages 201 - 210, (20150519), XP035504851 [A] 1-43 * the whole document * * figure 3 *

DOI:   http://dx.doi.org/10.1007/s12257-014-0575-6
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.