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Extract from the Register of European Patents

EP About this file: EP3334725

EP3334725 - MECHANISM OF RESISTANCE TO BET BROMODOMAIN INHIBITORS [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  22.07.2022
Database last updated on 05.10.2024
FormerRequest for examination was made
Status updated on  18.05.2018
FormerThe international publication has been made
Status updated on  18.02.2017
Most recent event   Tooltip27.08.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Dana-Farber Cancer Institute, Inc.
450 Brookline Avenue
Boston, MA 02215 / US
[2018/25]
Inventor(s)01 / POLYAK, Kornelia
11 Orchard Road
Brookline, MA 02445 / US
02 / SHU, Shaokun
183 High Street
Brookline, MA 02445 / US
03 / BRADNER, James E.
6 Buckskin Drive
Weston, MA 02493 / US
04 / LIN, Charles Yang
5520 La Branch Street
Houston, TX 77004 / US
 [2018/25]
Representative(s)Elkington and Fife LLP
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
[N/P]
Former [2018/25]HGF Limited
Saviour House
9 St. Saviourgate
York YO1 8NQ / GB
Application number, filing date16835823.210.08.2016
[2018/25]
WO2016US46318
Priority number, dateUS201562203128P10.08.2015         Original published format: US 201562203128 P
[2018/25]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017027571
Date:16.02.2017
Language:EN
[2017/07]
Type: A1 Application with search report 
No.:EP3334725
Date:20.06.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 16.02.2017 takes the place of the publication of the European patent application.
[2018/25]
Search report(s)International search report - published on:US16.02.2017
(Supplementary) European search report - dispatched on:EP03.07.2019
ClassificationIPC:C07D401/14, A61K31/517, C07D239/91, A61K45/06, A61K31/137, A61K31/5415, A61K31/551
[2019/17]
CPC:
A61K31/635 (EP,KR); A61K31/551 (EP,KR,US); A61K31/137 (EP,KR,US);
A61K31/4745 (KR); A61K31/496 (KR); A61K31/5415 (EP,KR,US);
A61K39/395 (KR); A61K45/06 (EP,US); A61P35/00 (EP,KR,US);
A61P43/00 (EP); C07D215/42 (EP); C07D255/04 (EP);
C07D471/04 (EP); C07D495/14 (EP); G01N33/57415 (US);
G01N33/6872 (EP,KR); A61K2300/00 (KR); G01N2800/52 (EP,KR) (-)
C-Set:
A61K31/137, A61K2300/00 (US,EP);
A61K31/5415, A61K2300/00 (US,EP);
A61K31/551, A61K2300/00 (EP,US);
A61K31/635, A61K2300/00 (US,EP)
Former IPC [2018/25]C07D401/14, A61K31/517, C07D239/91
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/25]
TitleGerman:RESISTENZMECHANISMUS GEGENÜBER BET-BROMDOMÄNEN-INHIBITOREN[2018/25]
English:MECHANISM OF RESISTANCE TO BET BROMODOMAIN INHIBITORS[2018/25]
French:MÉCANISME DE RÉSISTANCE AUX INHIBITEURS DE BROMODOMAINES DE BET[2018/25]
Entry into regional phase20.02.2018National basic fee paid 
20.02.2018Search fee paid 
20.02.2018Designation fee(s) paid 
20.02.2018Examination fee paid 
Examination procedure20.02.2018Examination requested  [2018/25]
20.02.2018Date on which the examining division has become responsible
29.01.2020Amendment by applicant (claims and/or description)
22.07.2022Despatch of a communication from the examining division (Time limit: M04)
22.11.2022Reply to a communication from the examining division
Fees paidRenewal fee
27.08.2018Renewal fee patent year 03
27.08.2019Renewal fee patent year 04
02.11.2020Renewal fee patent year 05
27.08.2021Renewal fee patent year 06
29.08.2022Renewal fee patent year 07
28.08.2023Renewal fee patent year 08
27.08.2024Renewal fee patent year 09
Penalty fee
Additional fee for renewal fee
31.08.202005   M06   Fee paid on   02.11.2020
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[Y]  - E BERNASCONI ET AL, "The BET bromodomain inhibitor OTX015 shows synergy with several anticancer agents in preclinical models of mantle cell lymphoma (MCL) and multiple myeloma (MM)", EUROPEAN JOURNAL OF CANCER, (20141121), vol. 50, no. S6, page 184, XP055551521 [Y] 1-7 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0959-8049(14)70694-X
 [Y]  - TEERU BIHANI ET AL, "Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers", ONCOTARGET, (20150210), vol. 6, no. 4, doi:10.18632/oncotarget.2964, XP055551925 [Y] 1-7 * figure 5 *

DOI:   http://dx.doi.org/10.18632/oncotarget.2964
 [Y]  - ALEJANDRO GUTIERREZ ET AL, "Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia", JOURNAL OF CLINICAL INVESTIGATION, GB, (20140203), vol. 124, no. 2, doi:10.1172/JCI65093, ISSN 0021-9738, pages 644 - 655, XP055551553 [Y] 1-7 * page 650, column 1 *

DOI:   http://dx.doi.org/10.1172/JCI65093
International search[XY]US2014005169  (ALBRECHT BRIAN K [US], et al);
 [A]US2014162971  (WANG LE [US], et al);
 [XY]US2014296218  (YOUNG RICHARD A [US], et al);
 [XY]WO2015070020  (DANA FARBER CANCER INST INC [US]);
 [XY]WO2015109286  (GILEAD SCIENCES INC [US]);
by applicantCA103867
 CA120184
 CA168504
 US6607916
 WO2006065724
 WO2007143081
 JP2008156311
 WO2008119109
 WO2009084693
 WO2009117769
 US2010256217
 US2010267673
 WO2011014366
 WO2011054843
 WO2011054851
 US2011143651
 US2011207789
 WO2011143669
 WO2011143660
 WO2012071374
 WO2012103059
 US8309582
 US8557812
 WO2013181488
 US8865901
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.