EP3337908 - METHODS AND COMPOSITIONS FOR ALTERING FUNCTION AND STRUCTURE OF CHROMATIN LOOPS AND/OR DOMAINS [Right-click to bookmark this link] | Status | Examination is in progress Status updated on 28.09.2019 Database last updated on 11.05.2024 | |
Former | Request for examination was made Status updated on 25.05.2018 | ||
Former | The international publication has been made Status updated on 25.02.2017 | Most recent event Tooltip | 11.04.2024 | New entry: Despatch of examination report + time limit | Applicant(s) | For all designated states The Broad Institute, Inc. 415 Main Street Cambridge, MA 02142 / US | For all designated states Baylor College of Medicine One Baylor Plaza Houston, TX 77030 / US | [2023/23] |
Former [2018/26] | For all designated states The Broad Institute, Inc. 415 Main Street Cambridge, MA 02142 / US | ||
For all designated states Baylor College of Medicine One Baylor Plaza Houston, TX 77030 / US | |||
For all designated states Lieberman Aiden, Erez 2205 Maroneal Street Houston, TX 77030 / US | |||
For all designated states Rao, Suhas 216 Rosse Lane Apt 201 Stanford, CA 94305 / US | |||
For all designated states Huang, Su-chen 5730 Reamer Street Houston, TX 77096 / US | |||
For all designated states Sanborn, Adrian L. One Baylor Plaza Houston, TX 77030 / US | |||
For all designated states Durand, Neva C. One Baylor Plaza Houston, TX 77030 / US | |||
For all designated states Huntley, Miriam One Baylor Plaza Houston, TX 77030 / US | |||
For all designated states Jewett, Andrew One Baylor Plaza Houston, TX 77030 / US | Inventor(s) | 01 /
LIEBERMAN AIDEN, Erez 2205 Maroneal Street Houston, TX 77030 / US | 02 /
LANDER, Eric, S. 74R Fayerweather Street Cambridge, MA 02138 / US | 03 /
RAO, Suhas 216 Rosse Lane Apt 201 Stanford, CA 94305 / US | 04 /
HUANG, Su-Chen 5730 Reamer Street Houston, TX 77096 / US | 05 /
SANBORN, Adrian, L. One Baylor Plaza Houston, TX 77030 / US | 06 /
DURAND, Neva, C. One Baylor Plaza Houston, TX 77030 / US | 07 /
HUNTLEY, Miriam One Baylor Plaza Houston, TX 77030 / US | 08 /
JEWETT, Andrew One Baylor Plaza Houston, TX 77030 / US | [2018/26] | Representative(s) | Impact Intellectual Property LLP 1 Sans Walk London EC1R 0LT / GB | [N/P] |
Former [2018/26] | Icely, Dominic Michael The IP Asset Partnership Limited Prama House 267 Banbury Road Oxford OX2 7HT / GB | Application number, filing date | 16837870.1 | 18.08.2016 | [2018/26] | WO2016US47644 | Priority number, date | US201562206606P | 18.08.2015 Original published format: US 201562206606 P | US201562239135P | 08.10.2015 Original published format: US 201562239135 P | US201662347585P | 08.06.2016 Original published format: US 201662347585 P | [2018/26] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2017031370 | Date: | 23.02.2017 | Language: | EN | [2017/08] | Type: | A1 Application with search report | No.: | EP3337908 | Date: | 27.06.2018 | Language: | EN | The application published by WIPO in one of the EPO official languages on 23.02.2017 takes the place of the publication of the European patent application. | [2018/26] | Search report(s) | International search report - published on: | US | 23.02.2017 | (Supplementary) European search report - dispatched on: | EP | 02.01.2019 | Classification | IPC: | C12Q1/68, C12N15/63, C12N15/87, C12N9/22 | [2018/26] | CPC: |
C07K14/47 (EP,US);
C12N15/113 (US);
C07K14/4702 (EP,US);
C12N15/11 (US);
C12N2310/14 (US);
C12N2310/20 (US)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2018/26] | Title | German: | VERFAHREN UND ZUSAMMENSETZUNGEN ZUR VERÄNDERUNG DER FUNKTION UND STRUKTUR VON CHROMATINSCHLEIFEN UND/ODER -DOMÄNEN | [2018/26] | English: | METHODS AND COMPOSITIONS FOR ALTERING FUNCTION AND STRUCTURE OF CHROMATIN LOOPS AND/OR DOMAINS | [2018/26] | French: | PROCÉDÉS ET COMPOSITIONS PERMETTANT DE CHANGER LA FONCTION ET LA STRUCTURE DE BOUCLES ET/OU DE DOMAINES DE CHROMATINE | [2018/26] | Entry into regional phase | 14.03.2018 | National basic fee paid | 14.03.2018 | Search fee paid | 14.03.2018 | Designation fee(s) paid | 14.03.2018 | Examination fee paid | Examination procedure | 14.03.2018 | Examination requested [2018/26] | 14.03.2018 | Date on which the examining division has become responsible | 19.07.2019 | Amendment by applicant (claims and/or description) | 02.10.2019 | Despatch of a communication from the examining division (Time limit: M04) | 11.02.2020 | Reply to a communication from the examining division | 25.05.2020 | Despatch of a communication from the examining division (Time limit: M04) | 25.09.2020 | Reply to a communication from the examining division | 29.10.2020 | Despatch of a communication from the examining division (Time limit: M04) | 26.02.2021 | Reply to a communication from the examining division | 31.05.2021 | Despatch of a communication from the examining division (Time limit: M06) | 29.11.2021 | Reply to a communication from the examining division | 30.01.2023 | Despatch of a communication from the examining division (Time limit: M06) | 28.07.2023 | Reply to a communication from the examining division | 10.04.2024 | Despatch of a communication from the examining division (Time limit: M04) | Fees paid | Renewal fee | 27.08.2018 | Renewal fee patent year 03 | 27.08.2019 | Renewal fee patent year 04 | 27.08.2020 | Renewal fee patent year 05 | 27.08.2021 | Renewal fee patent year 06 | 29.08.2022 | Renewal fee patent year 07 | 28.08.2023 | Renewal fee patent year 08 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [XI] - LUPIÁÑEZ DARÍO G ET AL, "Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions", CELL, CELL PRESS, AMSTERDAM, NL, (20150507), vol. 161, no. 5, doi:10.1016/J.CELL.2015.04.004, ISSN 0092-8674, pages 1012 - 1025, XP029129100 [X] 1-12,19,22-25 * abstract * [I] 13-18,20,21 DOI: http://dx.doi.org/10.1016/j.cell.2015.04.004 | [ ] - REN BING ET AL, "A CRISPR Connection between Chromatin Topology and Genetic Disorders", CELL, CELL PRESS, AMSTERDAM, NL, (20150521), vol. 161, no. 5, doi:10.1016/J.CELL.2015.04.047, ISSN 0092-8674, pages 955 - 957, XP029129141 DOI: http://dx.doi.org/10.1016/j.cell.2015.04.047 | [XI] - VARUN NARENDRA ET AL, "CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation", SCIENCE, US, (20150226), vol. 347, no. 6225, doi:10.1126/science.1259145, ISSN 0036-8075, pages 1017 - 1021, XP055534368 [X] 1-12,19,22-25 * abstract * [I] 13-18,20,21 DOI: http://dx.doi.org/10.1126/science.1259145 | [A] - SUHAS S.P. RAO ET AL, "A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping", CELL, AMSTERDAM, NL, (20141201), vol. 159, no. 7, doi:10.1016/j.cell.2014.11.021, ISSN 0092-8674, pages 1665 - 1680, XP055534145 [A] 1-25 * abstract * DOI: http://dx.doi.org/10.1016/j.cell.2014.11.021 | [A] - AMY D MARSHALL ET AL, "CTCF and BORIS in genome regulation and cancer", CURRENT OPINION IN GENETICS & DEVELOPMENT., XX, (20140201), vol. 24, doi:10.1016/j.gde.2013.10.011, ISSN 0959-437X, pages 8 - 15, XP055534160 [A] 1-25 * the whole document * DOI: http://dx.doi.org/10.1016/j.gde.2013.10.011 | International search | [Y]US2012115227 (COHEN-HAGUENAUER ODILE [FR], et al) [Y] 4, 5, 8, 10 * . Especially para [0010], [0011], [0016]. *; | [Y]WO2014172470 (WHITEHEAD BIOMEDICAL INST [US]) [Y] 6 * . Especially para [00107], [00108], [00406]. *; | [Y]WO2015033293 (CSIR [ZA]) [Y] 6 * . Especially pg 7 para 1-2. *; | [Y] - GUO et al., "CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function.", CELL, (20150813), vol. 162, no. 4, pages 900 - 910, XP055365405 [Y] 1-10 * . Especially abstract, pg 901 col 1 para 1, pg 901 col1 para 4, pg 901 col 2 para 2, pg 903 col 1 para 2, pg 905 col 2 para 4. * DOI: http://dx.doi.org/10.1016/j.cell.2015.07.038 | [Y] - ALIPOUR et al., "Self-organization of domain structures by DNA-loop-extruding enzymes.", Nucl Acids Res, (20121200), vol. 40, no. 22, pages 11202 - 11212, XP055365406 [Y] 1-10 * . Especially abstract, pg 11203 para 2. * DOI: http://dx.doi.org/10.1093/nar/gks925 | [XP] - SANBORN et al., "Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes.", PNAS, vol. 112, no. 47, pages E6456 - E6465, XP055365407 [XP] 1-5, 7-10 * . Entire article, especially abstract, pg E6461 fig 5A, pg E6463 fig 7. * DOI: http://dx.doi.org/10.1073/pnas.1518552112 |