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Extract from the Register of European Patents

EP About this file: EP3352858

EP3352858 - ANTIBODY THAT BINDS TO HUMAN PROGRAMMED DEATH LIGAND 2 (PD-L2) AND USES THEREOF [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  02.09.2022
Database last updated on 03.06.2024
FormerRequest for examination was made
Status updated on  29.06.2018
FormerThe international publication has been made
Status updated on  01.04.2017
Most recent event   Tooltip12.09.2023New entry: Renewal fee paid 
Applicant(s)For all designated states
Merck Sharp & Dohme LLC
126 East Lincoln Avenue
Rahway, New Jersey 07065 / US
[2022/42]
Former [2018/31]For all designated states
Merck Sharp & Dohme Corp.
126 East Lincoln Avenue
Rahway, NJ 07065-0907 / US
Inventor(s)01 / YEARLEY, Jennifer, H.
901 South California Avenue
Palo Alto, California 94304 / US
02 / LIANG, Linda
128 Ada Avenue Apt. 8
Mountain View, California 94043 / US
03 / BIGLER, Michael Eric
901 South California Avenue
Palo Alto, California 94304 / US
04 / GIBSON, Christopher John
707 Haldane Drive
Kennett Square, Pennsylvania 19348 / US
 [2018/31]
Representative(s)Merck Sharp & Dohme LLC
120 Moorgate
London EC2M 6UR / GB
[N/P]
Former [2018/31]Böhles, Elena
Merck Sharp & Dohme Limited
Hertford Road
Hoddesdon, Herts EN11 9BU / GB
Application number, filing date16849405.220.09.2016
[2018/31]
WO2016US52569
Priority number, dateUS201562221472P21.09.2015         Original published format: US 201562221472 P
[2018/31]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017053250
Date:30.03.2017
Language:EN
[2017/13]
Type: A1 Application with search report 
No.:EP3352858
Date:01.08.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 30.03.2017 takes the place of the publication of the European patent application.
[2018/31]
Search report(s)International search report - published on:US30.03.2017
(Supplementary) European search report - dispatched on:EP20.03.2019
ClassificationIPC:A61P35/00, C07K16/28, C07K16/46, C12N15/13, G01N33/574
[2019/14]
CPC:
C07K16/2827 (EP,US); A61K39/395 (US); A61P35/00 (EP,US);
G01N33/57492 (US); C07K2317/20 (US); C07K2317/52 (US);
C07K2317/56 (US); C07K2317/565 (US); C07K2317/567 (US);
C07K2317/76 (US); G01N2333/4704 (US) (-)
Former IPC [2018/31]A61P35/00, C07K16/28, C07K16/46, C12N15/13
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/31]
TitleGerman:AN DEN MENSCHLICHEN PROGRAMMIERTEN TODESLIGANDEN 2 (PD-L2) BINDENDER ANTIKÖRPER UND DESSEN VERWENDUNG[2018/31]
English:ANTIBODY THAT BINDS TO HUMAN PROGRAMMED DEATH LIGAND 2 (PD-L2) AND USES THEREOF[2018/31]
French:ANTICORPS QUI SE LIE À LA FORME HUMAINE DU LIGAND-2 DE LA PROTÉINE 1 DE MORT CELLULAIRE PROGRAMMÉE (PD-L2), ET UTILISATION DE CE DERNIER[2018/31]
Entry into regional phase23.04.2018National basic fee paid 
23.04.2018Search fee paid 
23.04.2018Designation fee(s) paid 
23.04.2018Examination fee paid 
Examination procedure19.04.2018Date on which the examining division has become responsible
23.04.2018Examination requested  [2018/31]
29.11.2019Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
22.01.2020Amendment by applicant (claims and/or description)
01.09.2022Despatch of a communication from the examining division (Time limit: M06)
06.03.2023Reply to a communication from the examining division
Request for further processing for:The application is deemed to be withdrawn due to failure to indicate the wish to proceed further with the application
22.01.2020Request for further processing filed
22.01.2020Full payment received (date of receipt of payment)
Request granted
12.02.2020Decision despatched
The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
22.01.2020Request for further processing filed
22.01.2020Full payment received (date of receipt of payment)
Request granted
12.02.2020Decision despatched
Fees paidRenewal fee
11.09.2018Renewal fee patent year 03
11.09.2019Renewal fee patent year 04
11.09.2020Renewal fee patent year 05
09.09.2021Renewal fee patent year 06
09.09.2022Renewal fee patent year 07
12.09.2023Renewal fee patent year 08
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Documents cited:Search[A]WO2010036959  (DANA FARBER CANCER INST INC [US], et al) [A] 1-20 * example -; claim - *;
 [XYI]WO2014151006  (GENENTECH INC [US], et al) [X] 18 * claim - * [Y] 20 [I] 19;
 [XYI]US9073994  (HONJO TASUKU [JP], et al) [X] 18 * claim - * [Y] 20 [I] 19;
 [XPAI]WO2016144673  (DANA FARBER CANCER INST INC [US]) [XP] 18,19 * page 2, line 23 - page 3, line 2; example -; claim - * * page 121, line 15 - line 23 * [A] 2,4,13,17[I] 1,3,5-12,14-16,20;
 [IAY]  - J. M. TAUBE ET AL, "Association of PD-1, PD-1 Ligands, and Other Features of the Tumor Immune Microenvironment with Response to Anti-PD-1 Therapy", CLINICAL CANCER RESEARCH, US, (20140408), vol. 20, no. 19, doi:10.1158/1078-0432.CCR-13-3271, ISSN 1078-0432, pages 5064 - 5074, XP055291958 [I] 1,3,5-12,14-16 * page 5065, column r, paragraph l * [A] 2,4,13,17-19 [Y] 20

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-13-3271
 [IAY]  - SHI MIN ET AL, "Expression of programmed cell death 1 ligand 2 (PD-L2) is a distinguishing feature of primary mediastinal (thymic) large B-cell lymphoma and associated with PDCD1LG2 copy gain.", THE AMERICAN JOURNAL OF SURGICAL PATHOLOGY, (201412), vol. 38, no. 12, ISSN 1532-0979, pages 1715 - 1723, XP002789151 [I] 1,3,5-12,14-16 * page 1716, column l, paragraph 1 * * page 1716, column r, paragraph 2 * [A] 2,4,13,17-19 [Y] 20

DOI:   http://dx.doi.org/10.1097/PAS.0b013e31823651cb
 [A]  - ANNE M. SCHULTHEIS ET AL, "PD-L1 expression in small cell neuroendocrine carcinomas", EUROPEAN JOURNAL OF CANCER, AMSTERDAM, NL, (20150201), vol. 51, no. 3, doi:10.1016/j.ejca.2014.12.006, ISSN 0959-8049, pages 421 - 426, XP055431576 [A] 1-20 * abstract *

DOI:   http://dx.doi.org/10.1016/j.ejca.2014.12.006
International search[A]US2008118511  (FREEMAN GORDON [US], et al) [A] 1-5, 7-10, 18, 19 * entire document entire document *;
 [A]US2014234296  (SHARMA MANOJ K [US], et al) [A] 1-5, 7-10, 18, 19* entire document *;
 [A]WO2015088847  (GLAXOSMITHKLINE LLC [US], et al) [A] 1-5, 7-10, 18, 19 * entire document *;
 [A]US2015197571  (FREEMAN GORDON J [US], et al) [A] 1-5, 7-10, 18, 19 * ) entire document *;
 [X]WO2015119923  (PFIZER [US], et al) [X] 18, 19 * entire document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.