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EP About this file: EP3327125

EP3327125 - RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (SINA) [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 11.06.2021 Database last updated on 23.04.2024
Former	The patent has been granted Status updated on 03.07.2020
Former	Grant of patent is intended Status updated on 03.02.2020
Former	Examination is in progress Status updated on 12.03.2019
Former	Request for examination was made Status updated on 07.12.2018
Former	The application has been published Status updated on 27.04.2018
Most recent event Tooltip	08.07.2022	Lapse of the patent in a contracting state New state(s): MK	published on 10.08.2022 [2022/32]
Applicant(s)	For all designated states Sirna Therapeutics, Inc. 300 Third Street Cambridge, MA 02142 / US
	[2018/22]
Inventor(s)	01 / Cancilla, Mark 1700 Owens Street San Francisco, California 94158 / US
	02 / Cunningham, James, J. 770 Sumneytown Pike West Point, Pennsylvania 19486 / US
	03 / Flanagan, W. Michael 1700 Owens Street San Francisco, California 94158 / US
	04 / Haringsma, Henry, J. 1700 Owens Street San Francisco, California 94158 / US
	05 / Kenski, Denise 1700 Owens Street San Francisco, California 94158 / US
	06 / Stanton, Matthew, G. 770 Sumneytown Pike West Point, Pennsylvania 19486 / US
	07 / Stirdivant, Steven, M. 17 Bittersweet Drive Doylestown, Pennsylvania 18901 / US
	08 / Willingham, Aarron 1700 Owens Street San Francisco, California 94158 / US
	[2018/22]
Representative(s)	Müller-Boré & Partner Patentanwälte PartG mbB Friedenheimer Brücke 21 80639 München / DE
	[2018/22]
Application number, filing date	17001756.0	25.10.2011
	[2018/22]
Priority number, date	US20100408303P	29.10.2010 Original published format: US 408303 P
	US20100408428P	29.10.2010 Original published format: US 408428 P
	[2018/22]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	EP3327125
	Date:	30.05.2018
	Language:	EN
	[2018/22]
	Type:	B1 Patent specification
	No.:	EP3327125
	Date:	05.08.2020
	Language:	EN
	[2020/32]
Search report(s)	(Supplementary) European search report - dispatched on:	EP	13.03.2018
Classification	IPC:	C12N15/113	[2018/22]
	CPC:	C12N15/113 (EP,US); A61K31/713 (US); C07H21/02 (EP,US); C12N15/111 (EP,US); C12N2310/14 (EP,US); C12N2310/315 (EP,US); (+) C12N2310/321 (US); C12N2310/3231 (EP,US); C12N2310/331 (EP,US); C12N2310/344 (US); C12N2310/346 (EP,US); C12N2310/351 (US); C12N2320/32 (EP,US); C12N2320/51 (EP,US) (-)
	C-Set:	C12N2310/321, C12N2310/3521 (US,EP); C12N2310/321, C12N2310/3527 (EP,US); C12N2310/322, C12N2310/3533 (US,EP)
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2019/02]
Former [2018/22]	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
Title	German:	RNA-INTERFERENZ-VERMITTELTE INHIBITION VON GENEXPRESSION UNTER VERWENDUNG KURZER INTERFERIERENDER NUKLEINSÄURE (SINA)	[2018/22]
	English:	RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (SINA)	[2018/22]
	French:	INHIBITION AU MOYEN D'INTERFÉRENCE ARN D'UNE EXPRESSION DE GÈNE UTILISANT DES ACIDES NUCLÉIQUES À PETIT INTERFÉRENT (SINA)	[2018/22]
Examination procedure	29.11.2018	Examination requested [2019/02]
	29.11.2018	Date on which the examining division has become responsible
	15.03.2019	Despatch of a communication from the examining division (Time limit: M04)
	10.07.2019	Reply to a communication from the examining division
	25.02.2020	Communication of intention to grant the patent
	23.06.2020	Receipt of the translation of the claim(s)
	25.06.2020	Fee for grant paid
	25.06.2020	Fee for publishing/printing paid
Parent application(s) Tooltip	EP11836946.1 / EP2632472
Divisional application(s)	EP20189118.1 / EP3766975
Opposition(s)	07.05.2021	No opposition filed within time limit [2021/28]
Fees paid	Renewal fee
	03.11.2017	Renewal fee patent year 03
	03.11.2017	Renewal fee patent year 04
	03.11.2017	Renewal fee patent year 05
	03.11.2017	Renewal fee patent year 06
	03.11.2017	Renewal fee patent year 07
	29.10.2018	Renewal fee patent year 08
	28.10.2019	Renewal fee patent year 09
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	HU	25.10.2011
	AL	05.08.2020
	AT	05.08.2020
	CY	05.08.2020
	CZ	05.08.2020
	DK	05.08.2020
	EE	05.08.2020
	ES	05.08.2020
	FI	05.08.2020
	HR	05.08.2020
	IT	05.08.2020
	LT	05.08.2020
	LV	05.08.2020
	MC	05.08.2020
	MK	05.08.2020
	MT	05.08.2020
	NL	05.08.2020
	PL	05.08.2020
	RO	05.08.2020
	RS	05.08.2020
	SE	05.08.2020
	SI	05.08.2020
	SK	05.08.2020
	SM	05.08.2020
	TR	05.08.2020
	LU	25.10.2020
	BE	31.10.2020
	BG	05.11.2020
	NO	05.11.2020
	GR	06.11.2020
	IS	05.12.2020
	PT	07.12.2020
	[2022/32]
Former [2022/27]	HU	25.10.2011
	AL	05.08.2020
	AT	05.08.2020
	CY	05.08.2020
	CZ	05.08.2020
	DK	05.08.2020
	EE	05.08.2020
	ES	05.08.2020
	FI	05.08.2020
	HR	05.08.2020
	IT	05.08.2020
	LT	05.08.2020
	LV	05.08.2020
	MC	05.08.2020
	MT	05.08.2020
	NL	05.08.2020
	PL	05.08.2020
	RO	05.08.2020
	RS	05.08.2020
	SE	05.08.2020
	SI	05.08.2020
	SK	05.08.2020
	SM	05.08.2020
	TR	05.08.2020
	LU	25.10.2020
	BE	31.10.2020
	BG	05.11.2020
	NO	05.11.2020
	GR	06.11.2020
	IS	05.12.2020
	PT	07.12.2020
Former [2021/36]	AL	05.08.2020
	AT	05.08.2020
	CZ	05.08.2020
	DK	05.08.2020
	EE	05.08.2020
	ES	05.08.2020
	FI	05.08.2020
	HR	05.08.2020
	IT	05.08.2020
	LT	05.08.2020
	LV	05.08.2020
	MC	05.08.2020
	NL	05.08.2020
	PL	05.08.2020
	RO	05.08.2020
	RS	05.08.2020
	SE	05.08.2020
	SI	05.08.2020
	SK	05.08.2020
	SM	05.08.2020
	LU	25.10.2020
	BE	31.10.2020
	BG	05.11.2020
	NO	05.11.2020
	GR	06.11.2020
	IS	05.12.2020
	PT	07.12.2020
Former [2021/34]	AL	05.08.2020
	AT	05.08.2020
	CZ	05.08.2020
	DK	05.08.2020
	EE	05.08.2020
	ES	05.08.2020
	FI	05.08.2020
	HR	05.08.2020
	IT	05.08.2020
	LT	05.08.2020
	LV	05.08.2020
	MC	05.08.2020
	NL	05.08.2020
	PL	05.08.2020
	RO	05.08.2020
	RS	05.08.2020
	SE	05.08.2020
	SK	05.08.2020
	SM	05.08.2020
	LU	25.10.2020
	BG	05.11.2020
	NO	05.11.2020
	GR	06.11.2020
	IS	05.12.2020
	PT	07.12.2020
Former [2021/31]	AL	05.08.2020
	AT	05.08.2020
	CZ	05.08.2020
	DK	05.08.2020
	EE	05.08.2020
	ES	05.08.2020
	FI	05.08.2020
	HR	05.08.2020
	LT	05.08.2020
	LV	05.08.2020
	MC	05.08.2020
	NL	05.08.2020
	PL	05.08.2020
	RO	05.08.2020
	RS	05.08.2020
	SE	05.08.2020
	SK	05.08.2020
	SM	05.08.2020
	LU	25.10.2020
	BG	05.11.2020
	NO	05.11.2020
	GR	06.11.2020
	IS	05.12.2020
	PT	07.12.2020
Former [2021/28]	AL	05.08.2020
	AT	05.08.2020
	CZ	05.08.2020
	DK	05.08.2020
	EE	05.08.2020
	ES	05.08.2020
	FI	05.08.2020
	HR	05.08.2020
	LT	05.08.2020
	LV	05.08.2020
	NL	05.08.2020
	PL	05.08.2020
	RO	05.08.2020
	RS	05.08.2020
	SE	05.08.2020
	SK	05.08.2020
	SM	05.08.2020
	BG	05.11.2020
	NO	05.11.2020
	GR	06.11.2020
	IS	05.12.2020
	PT	07.12.2020
Former [2021/25]	AL	05.08.2020
	AT	05.08.2020
	CZ	05.08.2020
	DK	05.08.2020
	EE	05.08.2020
	ES	05.08.2020
	FI	05.08.2020
	HR	05.08.2020
	LT	05.08.2020
	LV	05.08.2020
	NL	05.08.2020
	PL	05.08.2020
	RO	05.08.2020
	RS	05.08.2020
	SE	05.08.2020
	SM	05.08.2020
	BG	05.11.2020
	NO	05.11.2020
	GR	06.11.2020
	IS	05.12.2020
	PT	07.12.2020
Former [2021/22]	AT	05.08.2020
	CZ	05.08.2020
	DK	05.08.2020
	EE	05.08.2020
	ES	05.08.2020
	FI	05.08.2020
	HR	05.08.2020
	LT	05.08.2020
	LV	05.08.2020
	NL	05.08.2020
	PL	05.08.2020
	RO	05.08.2020
	RS	05.08.2020
	SE	05.08.2020
	SM	05.08.2020
	BG	05.11.2020
	NO	05.11.2020
	GR	06.11.2020
	IS	05.12.2020
	PT	07.12.2020
Former [2021/21]	AT	05.08.2020
	DK	05.08.2020
	ES	05.08.2020
	FI	05.08.2020
	HR	05.08.2020
	LT	05.08.2020
	LV	05.08.2020
	NL	05.08.2020
	PL	05.08.2020
	RS	05.08.2020
	SE	05.08.2020
	BG	05.11.2020
	NO	05.11.2020
	GR	06.11.2020
	IS	05.12.2020
	PT	07.12.2020
Former [2021/12]	AT	05.08.2020
	ES	05.08.2020
	FI	05.08.2020
	HR	05.08.2020
	LT	05.08.2020
	LV	05.08.2020
	NL	05.08.2020
	PL	05.08.2020
	RS	05.08.2020
	SE	05.08.2020
	BG	05.11.2020
	NO	05.11.2020
	GR	06.11.2020
	IS	05.12.2020
	PT	07.12.2020
Former [2021/10]	AT	05.08.2020
	ES	05.08.2020
	FI	05.08.2020
	HR	05.08.2020
	LT	05.08.2020
	LV	05.08.2020
	PL	05.08.2020
	RS	05.08.2020
	SE	05.08.2020
	BG	05.11.2020
	NO	05.11.2020
	GR	06.11.2020
	IS	05.12.2020
	PT	07.12.2020
Former [2021/09]	AT	05.08.2020
	ES	05.08.2020
	FI	05.08.2020
	LT	05.08.2020
	SE	05.08.2020
	BG	05.11.2020
	NO	05.11.2020
	GR	06.11.2020
	PT	07.12.2020
Former [2021/08]	ES	05.08.2020
	FI	05.08.2020
	LT	05.08.2020
	SE	05.08.2020
	BG	05.11.2020
	NO	05.11.2020
	PT	07.12.2020
Former [2021/07]	FI	05.08.2020
	LT	05.08.2020
	NO	05.11.2020
Documents cited:	Search	[A]US2004192626 (MCSWIGGEN JAMES [US], et al) [A] 1-15 * figures 1-77; tables IV,VI-VIII *;
		[A]US2009306184 (MCSWIGGEN JAMES [US], et al) [A] 1-15 * table IV *;
		[A]WO2010111471 (MERCK SHARP & DOHME [US], et al) [A] 1-15 * claims 10,11 *;
		[T] - H. J. HARINGSMA ET AL, "mRNA knockdown by single strand RNA is improved by chemical modifications", NUCLEIC ACIDS RESEARCH, (20120116), vol. 40, no. 9, doi:10.1093/nar/gkr1301, ISSN 0305-1048, pages 4125 - 4136, XP055108366 [T] * figure 2 * DOI: http://dx.doi.org/10.1093/nar/gkr1301
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