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EP3241843
European procedure
Extract from the Register of European Patents
EP About this file: EP3241843
| EP3241843 - SOLUBILITY OPTIMIZATION OF IMMUNOBINDERS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 03.06.2022 Database last updated on 03.06.2024 | |
| Former | The patent has been granted Status updated on 25.06.2021 | ||
| Former | Grant of patent is intended Status updated on 16.02.2021 | ||
| Former | Examination is in progress Status updated on 08.03.2019 | ||
| Former | Request for examination was made Status updated on 06.10.2017 | Most recent event Tooltip | 03.06.2022 | No opposition filed within time limit | published on 06.07.2022 [2022/27] | Applicant(s) | For all designated states Novartis AG Lichtstrasse 35 4056 Basel / CH | [2020/52] |
| Former [2017/45] | For all designated states ESBATech, an Alcon Biomedical Research Unit LLC Wagistrasse 21 8952 Schlieren / CH | Inventor(s) | 01 /
BORRAS, Leonardo c/o Novartis AG Lichtstrasse 35 4056 Basel / CH | 02 /
URECH, David c/o Novartis AG Lichtstrasse 35 4056 Basel / CH | [2021/07] |
| Former [2017/45] | 01 /
BORRAS, Leonardo c/o ESBATech, an Alcon Biomedical Research Unit LLC Wagistrasse 21 8952 Schlieren / CH | ||
| 02 /
URECH, David c/o ESBATech, an Alcon Biomedical Research Unit LLC Wagistrasse 21 8952 Schlieren / CH | Representative(s) | Grünecker Patent- und Rechtsanwälte PartG mbB Leopoldstraße 4 80802 München / DE | [2017/45] | Application number, filing date | 17161990.1 | 25.06.2009 | [2017/45] | Priority number, date | US20080075692P | 25.06.2008 Original published format: US 75692 P | [2017/45] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP3241843 | Date: | 08.11.2017 | Language: | EN | [2017/45] | Type: | B1 Patent specification | No.: | EP3241843 | Date: | 28.07.2021 | Language: | EN | [2021/30] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 28.07.2017 | Classification | IPC: | C07K16/22, C07K16/24 | [2017/45] | CPC: |
C07K16/241 (EP,CN,KR,US);
A61K39/395 (KR);
A61K47/10 (RU);
A61K47/12 (RU);
A61K47/44 (RU);
A61K9/0014 (RU);
A61P17/00 (EP);
A61P35/00 (EP);
A61P37/06 (EP);
A61P43/00 (EP);
C07K16/22 (EP,CN,KR,US);
C07K2317/56 (CN);
C07K2317/567 (EP,US);
C07K2317/569 (CN);
C07K2317/622 (EP,CN,US);
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR [2017/45] | Title | German: | LÖSLICHKEITSOPTIMIERUNG VON IMMUNBINDERN | [2017/45] | English: | SOLUBILITY OPTIMIZATION OF IMMUNOBINDERS | [2017/45] | French: | OPTIMISATION DE SOLUBILITÉ D'AGENTS DE LIAISON IMMUNOLOGIQUE | [2017/45] | Examination procedure | 21.03.2017 | Examination requested [2017/45] | 21.03.2017 | Date on which the examining division has become responsible | 08.05.2018 | Amendment by applicant (claims and/or description) | 13.03.2019 | Despatch of a communication from the examining division (Time limit: M04) | 23.07.2019 | Reply to a communication from the examining division | 11.12.2019 | Despatch of a communication from the examining division (Time limit: M02) | 14.02.2020 | Reply to a communication from the examining division | 17.02.2021 | Communication of intention to grant the patent | 17.06.2021 | Fee for grant paid | 17.06.2021 | Fee for publishing/printing paid | 17.06.2021 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP09768694.3 / EP2307455 | Divisional application(s) | EP21183919.6 Application withdrawn : 06.10.2021 | Opposition(s) | 29.04.2022 | No opposition filed within time limit [2022/27] | Fees paid | Renewal fee | 21.03.2017 | Renewal fee patent year 03 | 21.03.2017 | Renewal fee patent year 04 | 21.03.2017 | Renewal fee patent year 05 | 21.03.2017 | Renewal fee patent year 06 | 21.03.2017 | Renewal fee patent year 07 | 21.03.2017 | Renewal fee patent year 08 | 25.09.2017 | Renewal fee patent year 09 | 12.06.2018 | Renewal fee patent year 10 | 13.06.2019 | Renewal fee patent year 11 | 15.06.2020 | Renewal fee patent year 12 | 14.06.2021 | Renewal fee patent year 13 | Penalty fee | Additional fee for renewal fee | 30.06.2017 | 09 M06 Fee paid on 25.09.2017 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | CZ | 28.07.2021 | EE | 28.07.2021 | [2022/24] | Documents cited: | Search | [AD]US6815540 (PLUECKTHUN ANDREAS [CH], et al) [AD] 1-5 * abstract * * column 10 - column 13 * * table 1 *; | [XI] - JUNG S ET AL, "Selection for improved protein stability by phage display", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, (19991119), vol. 294, no. 1, ISSN 0022-2836, pages 163 - 180, XP004461860 [X] 1-4 * abstract * * last 5 lines; page 164 * * page 165, column l * * table 1 * [I] 5 DOI: http://dx.doi.org/10.1006/jmbi.1999.3196 | [A] - NIEBA L ET AL, "Disrupting the hydrophobic patches at the antibody variable/constant domain interface: Improved in vivo folding and physical characterization of an engineered scFv fragment", PROTEIN ENGINEERING, OXFORD UNIVERSITY PRESS, SURREY, GB, (19970101), vol. 10, no. 4, ISSN 0269-2139, pages 435 - 444, XP002249462 [A] 1-5 * the whole document * DOI: http://dx.doi.org/10.1093/protein/10.4.435 | [A] - DAVIES J ET AL, "'Camelising' human antibody fragments: NMR studies on VH domains", FEBS LETTERS, ELSEVIER, AMSTERDAM, NL, vol. 339, no. 3, ISSN 0014-5793, (19940221), pages 285 - 290, (19940221), XP025614903 [A] 1-5 * abstract * * discussion * DOI: http://dx.doi.org/10.1016/0014-5793(94)80432-X | [A] - DAVIES J ET AL, "SINGLE ANTIBODY DOMAINS AS SMALL RECOGNITION UNITS: DESIGN AND IN VITRO ANTIGEN SELECTION OF CAMELIZED, HUMAN VH DOMAINS WITH IMPROVED PROTEIN STABILITY", PROTEIN ENGINEERING, OXFORD UNIVERSITY PRESS, SURREY, GB, (19960101), vol. 9, no. 6, ISSN 0269-2139, pages 531 - 537, XP000971767 [A] 1-5 * abstract * | by applicant | US5714350 | US5736137 | US5824307 | WO9916873 | WO0063243 | WO0148017 | US6258562 | WO0164942 | US6350861 | WO0220565 | US6455043 | WO02088171 | US6602977 | WO03097697 | US6673901 | US6682734 | US6703199 | US6740734 | WO2004044011 | EP1242457 | US6815540 | EP1479694 | EP1506236 | WO2005019254 | US6884879 | US7078490 | WO2006083275 | US7119171 | WO2006131013 | WO2008006235 | WO2008110348 | WO2009000098 | - NIEBA, L ET AL., PROT. ENG., (1997), vol. 10, pages 435 - 444 | - TAN, P.H. ET AL., BIOPHYS. J., (1988), vol. 75, pages 1473 - 1482 | - PLUCKTHUN, A, BIOCHEM., (1998), vol. 37, pages 13120 - 13127 | - WORN, A; PLUCKTHUN, A., BIOCHEM., (1999), vol. 38, pages 8739 - 8750 | - JUNG, S; PLUCKTHUN, A., PROT. ENG., (1997), vol. 10, pages 959 - 966 | - WORN, A.; PLUCKTHUN, A., J. MOL. BIOL., (2001), vol. 305, pages 989 - 1010 | - JUNG, S.; HONEGGER, A.; PLUCKTHUN, A, PROT. ENG., (1997), vol. 10, pages 959 - 966 | - SKERRA A.; PLUCKTHUN, A, SCIENCE, (1988), vol. 240, pages 1038 - 41 | - BIRD, R.E. ET AL., SCIENCE, (1988), vol. 242, pages 423 - 26 | - HUSTON, J.S. ET AL., PROC. NATL. ACAD. SCI. USA, (1988), vol. 85, pages 5879 - 83 | - NEEDLEMAN ET AL., J. MOL. BIOL., (1970), vol. 48, pages 443 - 453 | - ROSE ET AL., SCIENCE, (1985), vol. 229, pages 834 - 838 | - CORNETTE ET AL., J. MOL. BIOL., (1987), vol. 195, pages 659 - 685 | - WARD ET AL., NATURE, (1989), vol. 341, pages 544 - 546 | - HAMERS-CASTERMAN ET AL., NATURE, (1993), vol. 363, pages 446 - 448 | - DUMOULIN ET AL., PROTEIN SCIENCE, (2002), vol. 11, pages 500 - 515 | - ATHA ET AL., "Mechanism of Precipitation of Proteins by Polyethylene Glycols", JBC, (1981), vol. 256, pages 12108 - 12117 | - ARAKAWA ET AL., J. BIOCHEM, (1996), vol. 120, pages 657 - 662 | - KUNG; GOLDSTEIN ET AL., SCIENCE, (1979), vol. 206, pages 347 - 349 | - BERGE, S. M. ET AL., J. PHARM. SCI., (1977), vol. 66, pages 1 - 19 | - HONEGGER, A.; PLUCKTHUN, A., J. MOL. BIOL., (2001), vol. 309, pages 657 - 670 | - HONEGGER ET AL., J. MOL. BIOL., (2001), vol. 309, pages 657 - 670 | US20060819378 | US20070899907 | US20080069056 | WO2008CH00285 |