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Extract from the Register of European Patents

EP About this file: EP3260127

EP3260127 - AROMATIC-CATIONIC PEPTIDE FOR USE IN A METHOD OF TREATING CEREBRAL ISCHEMIA [Right-click to bookmark this link]
Former [2017/52]AROMATIC-CATIONIC PEPTIDE FOR USE IN A METHOD FOR REDUCING CD36 EXPRESSION
[2018/47]
StatusNo opposition filed within time limit
Status updated on  06.03.2020
Database last updated on 15.06.2024
FormerThe patent has been granted
Status updated on  29.03.2019
FormerGrant of patent is intended
Status updated on  21.11.2018
FormerRequest for examination was made
Status updated on  22.06.2018
FormerThe application has been published
Status updated on  24.11.2017
Most recent event   Tooltip16.07.2021Lapse of the patent in a contracting state
New state(s): HU		published on 18.08.2021  [2021/33]
Applicant(s)For all designated states
Cornell Research Foundation, Inc.
395 Pine Tree Road, Suite 310
Ithaca, NY 14850 / US
[2017/52]
Inventor(s)01 / SZETO, Hazel H.
50 East 89th Street
Apartment 25A
New York, NY 10128 / US
02 / LIU, Shaoyi
209B E. Harriet Avenue
Palisades Park, NJ 07650 / US
03 / CHO, Sunghee
555 Central Park Avenue
Unit 125
Scaresdale, NY 10583 / US
 [2017/52]
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[N/P]
Former [2017/52]J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Application number, filing date17172250.718.09.2006
[2017/52]
Priority number, dateUS200571817005P16.09.2005         Original published format: US 71817005 P
[2019/16]
Former [2017/52]US20050718170P16.09.2005
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3260127
Date:27.12.2017
Language:EN
[2017/52]
Type: B1 Patent specification 
No.:EP3260127
Date:01.05.2019
Language:EN
[2019/18]
Search report(s)(Supplementary) European search report - dispatched on:EP30.10.2017
ClassificationIPC:A61K38/03, A61K38/07, A61P9/10
[2017/52]
CPC:
A61K38/08 (EP,CN,KR,US); A61K38/07 (CN,KR,US); C07K5/101 (KR,US);
A61K38/03 (EP,KR,US); A61K38/06 (EP,US); A61K38/10 (KR);
A61K48/00 (KR); A61P13/02 (EP); A61P13/12 (EP);
A61P15/00 (EP); A61P25/00 (EP); A61P25/28 (EP);
A61P27/02 (EP); A61P29/00 (EP); A61P3/04 (EP);
A61P3/06 (EP); A61P3/10 (EP,US); A61P43/00 (EP);
A61P9/00 (EP); A61P9/10 (EP); C07K14/705 (EP,KR,US);
C07K5/1008 (EP,KR,US); C07K5/1016 (EP,KR,US); C07K5/1019 (EP,KR,US);
C07K5/1024 (EP,KR,US); A61K38/00 (EP,US) (-)
C-Set:
A61K38/07, A61K2300/00 (CN)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2018/30]
Former [2017/52]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:AROMATISCH-KATIONISCHES PEPTID ZUR VERWENDUNG IN EINEM VERFAHREN ZUR BEHANDLUNG VON ZEREBRALER ISCHÄMIE[2018/47]
English:AROMATIC-CATIONIC PEPTIDE FOR USE IN A METHOD OF TREATING CEREBRAL ISCHEMIA[2018/47]
French:PEPTIDE AROMATIQUE-CATIONIQUE DESTINÉ À ÊTRE UTILISÉ DANS UN PROCÉDÉ DE TRAITEMENT DE L'ISCHÉMIE CÉRÉBRALE[2018/47]
Former [2017/52]AROMATISCH-KATIONISCHES PEPTID ZUR VERWENDUNG IN EINEM VERFAHREN ZUR REDUZIERUNG DER CD36-EXPRESSION
Former [2017/52]AROMATIC-CATIONIC PEPTIDE FOR USE IN A METHOD FOR REDUCING CD36 EXPRESSION
Former [2017/52]PEPTIDE AROMATIQUE-CATIONIQUE DESTINÉ À ÊTRE UTILISÉ DANS UN PROCÉDÉ DE RÉDUCTION DE L'EXPRESSION CD36
Examination procedure22.05.2017Date on which the examining division has become responsible
14.06.2018Amendment by applicant (claims and/or description)
14.06.2018Examination requested  [2018/30]
22.11.2018Communication of intention to grant the patent
19.03.2019Fee for grant paid
19.03.2019Fee for publishing/printing paid
19.03.2019Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP06814864.2  / EP1931369
EP16176957.5  / EP3095454
Divisional application(s)EP19160103.8  / EP3549594
EP20167024.7  / EP3725324
Opposition(s)04.02.2020No opposition filed within time limit [2020/15]
Fees paidRenewal fee
22.05.2017Renewal fee patent year 03
22.05.2017Renewal fee patent year 04
22.05.2017Renewal fee patent year 05
22.05.2017Renewal fee patent year 06
22.05.2017Renewal fee patent year 07
22.05.2017Renewal fee patent year 08
22.05.2017Renewal fee patent year 09
22.05.2017Renewal fee patent year 10
22.05.2017Renewal fee patent year 11
27.09.2017Renewal fee patent year 12
27.09.2018Renewal fee patent year 13
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU18.09.2006
AT01.05.2019
CY01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
TR01.05.2019
BG01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
GB18.09.2019
IE18.09.2019
LU18.09.2019
BE30.09.2019
CH30.09.2019
FR30.09.2019
LI30.09.2019
[2021/33]
Former [2021/26]AT01.05.2019
CY01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
TR01.05.2019
BG01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
GB18.09.2019
IE18.09.2019
LU18.09.2019
BE30.09.2019
CH30.09.2019
FR30.09.2019
LI30.09.2019
Former [2020/48]AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
TR01.05.2019
BG01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
GB18.09.2019
IE18.09.2019
LU18.09.2019
BE30.09.2019
CH30.09.2019
FR30.09.2019
LI30.09.2019
Former [2020/38]AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
TR01.05.2019
BG01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
IE18.09.2019
LU18.09.2019
BE30.09.2019
CH30.09.2019
LI30.09.2019
Former [2020/36]AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
TR01.05.2019
BG01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
IE18.09.2019
LU18.09.2019
CH30.09.2019
LI30.09.2019
Former [2020/35]AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
TR01.05.2019
BG01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
LU18.09.2019
CH30.09.2019
LI30.09.2019
Former [2020/34]AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
TR01.05.2019
BG01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
CH30.09.2019
LI30.09.2019
Former [2020/25]AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
TR01.05.2019
BG01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/17]AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RO01.05.2019
SE01.05.2019
SK01.05.2019
TR01.05.2019
BG01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/12]AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RO01.05.2019
SE01.05.2019
SK01.05.2019
BG01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/11]AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RO01.05.2019
SE01.05.2019
SK01.05.2019
BG01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/10]AT01.05.2019
CZ01.05.2019
DK01.05.2019
ES01.05.2019
FI01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RO01.05.2019
SE01.05.2019
BG01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/09]CZ01.05.2019
DK01.05.2019
ES01.05.2019
FI01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
SE01.05.2019
BG01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/04]ES01.05.2019
FI01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
SE01.05.2019
BG01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2019/51]ES01.05.2019
FI01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
SE01.05.2019
BG01.08.2019
GR02.08.2019
PT01.09.2019
Former [2019/49]ES01.05.2019
FI01.05.2019
LT01.05.2019
NL01.05.2019
SE01.05.2019
PT01.09.2019
Former [2019/48]ES01.05.2019
FI01.05.2019
LT01.05.2019
SE01.05.2019
PT01.09.2019
Former [2019/47]ES01.05.2019
FI01.05.2019
LT01.05.2019
Documents cited:Search[A]WO2004070054  (CORNELL RES FOUNDATION INC [US], et al) [A] 1-4 * claim 40 *;
 [A]WO2005044295  (SAHLTECH AB [SE], et al) [A] 1-4 * page 8, line 16 - page 12, line 3 *;
 [A]WO2005072295  (CORNELL RES FOUNDATION INC [US], et al) [A] 1-4 * claim 39 *;
 [A]  - ANNIE DEMERS ET AL, "Identification of the growth hormone-releasing peptide binding site in CD36: a photoaffinity cross-linking study", JOURNAL OF JAPANESE BIOCHEMICAL SOC, XX, XX, (20040101), vol. 382, doi:10.1042/BJ20040036, pages 417 - 424, XP007914579 [A] 1-4 * abstract *

DOI:   http://dx.doi.org/10.1042/BJ20040036
 [A]  - S. CHO, "The Class B Scavenger Receptor CD36 Mediates Free Radical Production and Tissue Injury in Cerebral Ischemia", JOURNAL OF NEUROSCIENCE, US, (20050309), vol. 25, no. 10, doi:10.1523/JNEUROSCI.0035-05.2005, ISSN 0270-6474, pages 2504 - 2512, XP055417299 [A] 1-4

DOI:   http://dx.doi.org/10.1523/JNEUROSCI.0035-05.2005
 [XP]  - S Cho ET AL, "A cell-permeable antioxidant peptide attenuates CD36-mediated ischemic injury via normalizing redox state.", Neuroscience meeting planner, Society for Neuroscience, (20051114), URL: http://www.sfn.org/absarchive/abstract.aspx, (20120320), XP055022440 [XP] 1-3 * abstract *
 [XP]  - H H SZETO, "Mitochondria-Targeted Peptide Antioxidants: Novel Neuroprotective Agents", THE AAPS JOURNAL, (20060818), vol. 8, no. 3, pages E521 - E531, XP055020617 [XP] 1-3 * page E527, column r, paragraph 3 *

DOI:   http://dx.doi.org/10.1208/aapsj080362
 [T]  - SUNGHEE CHO ET AL, "A novel cell-permeable antioxidant peptide, SS31, attenuates ischemic brain injury by down-regulating CD36", JOURNAL OF BIOLOGICAL CHEMISTRY, THE AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, INC, US, vol. 282, no. 7, doi:10.1074/JBC.M609388200, ISSN 0021-9258, (20070216), pages 4634 - 4642, (20061218), XP002638723

DOI:   http://dx.doi.org/10.1074/JBC.M609388200
 [T]  - SUNGHEE CHO ET AL, "CD36: A multi-modal target for acute stroke therapy", JOURNAL OF NEUROCHEMISTRY, (20090501), vol. 109, doi:10.1111/j.1471-4159.2009.05801.x, ISSN 0022-3042, pages 126 - 132, XP055020732

DOI:   http://dx.doi.org/10.1111/j.1471-4159.2009.05801.x
 [T]  - EUN-HEE KIM ET AL, "Targeting CD36-Mediated Inflammation Reduces Acute Brain Injury in Transient, but not Permanent, Ischemic Stroke", CNS NEUROSCIENCE & THERAPEUTICS, GB, (20140912), vol. 21, no. 4, doi:10.1111/cns.12326, ISSN 1755-5930, pages 385 - 391, XP055417439

DOI:   http://dx.doi.org/10.1111/cns.12326
by applicantWO02083106
    - FEBBRAIO M; PODREZ EA; SMITH JD; HAJJAR DP; HAZEN SL ET AL., "Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice", J CLINICAL INVESTIGATION, (2000), vol. 105, doi:doi:10.1172/JCI9259, pages 1049 - 1056, XP002487573

DOI:   http://dx.doi.org/10.1172/JCI9259
    - FEBBRAIO M.; HAJJAR DP; SILVERSTEIN RL, "CD36: a class B scavenger receptor involved in angiogenesis, atherosclerosis, inflammation, and lipid metabolism", JOURNAL OF CLINICAL INVESTIGATION, (2001), vol. 108, pages 785 - 791, XP002487577
    - "Solid Phase Peptide Synthesis", Methods Enzymol., ACADEMIC PRESS, INC, (1997), vol. 289
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.