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Extract from the Register of European Patents

EP About this file: EP3422005

EP3422005 - DETERMINING ENRICHMENTS OF TRACERS OF GLUCOSE BY MASS SPECTROMETRY [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  19.03.2021
Database last updated on 11.09.2024
FormerThe patent has been granted
Status updated on  10.04.2020
FormerGrant of patent is intended
Status updated on  01.12.2019
FormerRequest for examination was made
Status updated on  05.07.2019
FormerThe application has been published
Status updated on  30.11.2018
Most recent event   Tooltip15.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 17.08.2022  [2022/33]
Applicant(s)For all designated states
Medizinische Universität Graz
Auenbruggerplatz 2
8036 Graz / AT
[2019/01]
Inventor(s)01 / Regittnig, Werner
Liebiggasse 14
8010 Graz / AT
02 / Köfeler, Harald
Sonnenhang 1
8046 Stattegg / AT
03 / Trötzmüller, Martin
Edelsgrub 218
8302 Nestelbach / AT
04 / Triebl, Alexander
Flugplatzstraße 24
7061 Trausdorf / AT
 [2019/01]
Representative(s)Dilg, Haeusler, Schindelmann Patentanwaltsgesellschaft mbH
Leonrodstraße 58
80636 München / DE
[2020/20]
Former [2019/01]Dilg, Haeusler, Schindelmann Patentanwaltsgesellschaft mbH
Leonrodstrasse 58
80636 München / DE
Application number, filing date17178182.627.06.2017
[2019/01]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3422005
Date:02.01.2019
Language:EN
[2019/01]
Type: B1 Patent specification 
No.:EP3422005
Date:13.05.2020
Language:EN
[2020/20]
Search report(s)(Supplementary) European search report - dispatched on:EP15.12.2017
ClassificationIPC:G01N33/58, H01J49/00, G01N30/72
[2019/01]
CPC:
G01N33/66 (EP,US); G01N30/72 (EP,US); G01N33/583 (EP,US);
G01N2030/8813 (EP); G01N2030/8836 (EP,US); H01J49/0027 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/32]
Former [2019/01]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
TitleGerman:BESTIMMUNG DER ANREICHERUNGEN VON TRACERN VON GLUCOSE MITTELS MASSENSPEKTROMETRIE[2019/01]
English:DETERMINING ENRICHMENTS OF TRACERS OF GLUCOSE BY MASS SPECTROMETRY[2019/01]
French:DÉTERMINATION D'ENRICHISSEMENTS DE TRACEURS DE GLUCOSE PAR SPECTROMÉTRIE DE MASSE[2019/01]
Examination procedure28.06.2019Amendment by applicant (claims and/or description)
28.06.2019Examination requested  [2019/32]
28.06.2019Date on which the examining division has become responsible
02.12.2019Communication of intention to grant the patent
06.04.2020Fee for grant paid
06.04.2020Fee for publishing/printing paid
06.04.2020Receipt of the translation of the claim(s)
Opposition(s)16.02.2021No opposition filed within time limit [2021/16]
Fees paidRenewal fee
14.06.2019Renewal fee patent year 03
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU27.06.2017
AL13.05.2020
CY13.05.2020
CZ13.05.2020
EE13.05.2020
FI13.05.2020
HR13.05.2020
LT13.05.2020
LV13.05.2020
MC13.05.2020
MK13.05.2020
MT13.05.2020
PL13.05.2020
RO13.05.2020
RS13.05.2020
SI13.05.2020
SK13.05.2020
SM13.05.2020
TR13.05.2020
IE27.06.2020
LU27.06.2020
BE30.06.2020
BG13.08.2020
NO13.08.2020
GR14.08.2020
IS13.09.2020
PT14.09.2020
[2022/33]
Former [2022/27]HU27.06.2017
AL13.05.2020
CY13.05.2020
CZ13.05.2020
EE13.05.2020
FI13.05.2020
HR13.05.2020
LT13.05.2020
LV13.05.2020
MC13.05.2020
MT13.05.2020
PL13.05.2020
RO13.05.2020
RS13.05.2020
SI13.05.2020
SK13.05.2020
SM13.05.2020
TR13.05.2020
IE27.06.2020
LU27.06.2020
BE30.06.2020
BG13.08.2020
NO13.08.2020
GR14.08.2020
IS13.09.2020
PT14.09.2020
Former [2021/24]AL13.05.2020
CZ13.05.2020
EE13.05.2020
FI13.05.2020
HR13.05.2020
LT13.05.2020
LV13.05.2020
MC13.05.2020
PL13.05.2020
RO13.05.2020
RS13.05.2020
SI13.05.2020
SK13.05.2020
SM13.05.2020
IE27.06.2020
LU27.06.2020
BE30.06.2020
BG13.08.2020
NO13.08.2020
GR14.08.2020
IS13.09.2020
PT14.09.2020
Former [2021/20]AL13.05.2020
CZ13.05.2020
EE13.05.2020
FI13.05.2020
HR13.05.2020
LT13.05.2020
LV13.05.2020
MC13.05.2020
PL13.05.2020
RO13.05.2020
RS13.05.2020
SK13.05.2020
SM13.05.2020
IE27.06.2020
LU27.06.2020
BG13.08.2020
NO13.08.2020
GR14.08.2020
IS13.09.2020
PT14.09.2020
Former [2021/15]AL13.05.2020
CZ13.05.2020
EE13.05.2020
FI13.05.2020
HR13.05.2020
LT13.05.2020
LV13.05.2020
MC13.05.2020
PL13.05.2020
RO13.05.2020
RS13.05.2020
SK13.05.2020
SM13.05.2020
LU27.06.2020
BG13.08.2020
NO13.08.2020
GR14.08.2020
IS13.09.2020
PT14.09.2020
Former [2021/14]AL13.05.2020
CZ13.05.2020
EE13.05.2020
FI13.05.2020
HR13.05.2020
LT13.05.2020
LV13.05.2020
MC13.05.2020
PL13.05.2020
RO13.05.2020
RS13.05.2020
SK13.05.2020
SM13.05.2020
BG13.08.2020
NO13.08.2020
GR14.08.2020
IS13.09.2020
PT14.09.2020
Former [2021/10]AL13.05.2020
CZ13.05.2020
EE13.05.2020
FI13.05.2020
HR13.05.2020
LT13.05.2020
LV13.05.2020
PL13.05.2020
RO13.05.2020
RS13.05.2020
SK13.05.2020
SM13.05.2020
BG13.08.2020
NO13.08.2020
GR14.08.2020
IS13.09.2020
PT14.09.2020
Former [2021/09]AL13.05.2020
CZ13.05.2020
EE13.05.2020
FI13.05.2020
HR13.05.2020
LT13.05.2020
LV13.05.2020
RO13.05.2020
RS13.05.2020
SM13.05.2020
BG13.08.2020
NO13.08.2020
GR14.08.2020
IS13.09.2020
PT14.09.2020
Former [2021/04]AL13.05.2020
FI13.05.2020
HR13.05.2020
LT13.05.2020
LV13.05.2020
RS13.05.2020
BG13.08.2020
NO13.08.2020
GR14.08.2020
IS13.09.2020
PT14.09.2020
Former [2021/01]FI13.05.2020
HR13.05.2020
LT13.05.2020
LV13.05.2020
RS13.05.2020
BG13.08.2020
NO13.08.2020
GR14.08.2020
IS13.09.2020
PT14.09.2020
Former [2020/51]FI13.05.2020
HR13.05.2020
LT13.05.2020
LV13.05.2020
RS13.05.2020
NO13.08.2020
GR14.08.2020
IS13.09.2020
PT14.09.2020
Former [2020/50]FI13.05.2020
HR13.05.2020
LT13.05.2020
LV13.05.2020
NO13.08.2020
GR14.08.2020
IS13.09.2020
PT14.09.2020
Former [2020/48]FI13.05.2020
LT13.05.2020
NO13.08.2020
IS13.09.2020
PT14.09.2020
Former [2020/47]LT13.05.2020
NO13.08.2020
IS13.09.2020
Former [2020/46]IS13.09.2020
Documents cited:Search[Y]WO2011084751  (QUEST DIAGNOSTICS INVEST INC [US], et al) [Y] 17 * the whole document, in particular the claims *;
 [Y]WO2014105858  (QUEST DIAGNOSTICS INVEST INC [US]) [Y] 17 * the whole document, in particular the claims *;
 [Y]WO2016141204  (QUEST DIAGNOSTICS INVEST LLC [US]) [Y] 17 * the whole document, in particular the claims *;
 [XDY]  - G. TOFFOLO ET AL, "Glucose Fluxes During OGTT in Adolescents Assessed by a Stable Isotope Triple Tracer Method", JOURNAL OF PEDIATRIC ENDOCRINOLOGY AND METABOLISM., DE, (20080101), vol. 21, no. 1, doi:10.1515/JPEM.2008.21.1.31, ISSN 0334-018X, XP055431422 [XD] 16 * the whole document, in particular the abstract * [Y] 17

DOI:   http://dx.doi.org/10.1515/JPEM.2008.21.1.31
 [XDY]  - RITA BASU ET AL, "Use of a novel triple-tracer approach to assess postprandial glucose metabolism", AMERICAN JOURNAL OF PHYSIOLOGY: ENDOCRINOLOGY AND METABOLISM., US, (20030101), vol. 284, no. 1, doi:10.1152/ajpendo.00190.2001, ISSN 0193-1849, pages E55 - E69, XP055431434 [XD] 16 * the whole document, in particular the abstract * [Y] 17

DOI:   http://dx.doi.org/10.1152/ajpendo.00190.2001
 [XDY]  - A. HAIDAR ET AL, "Validity of triple- and dual-tracer techniques to estimate glucose appearance", AMERICAN JOURNAL OF PHYSIOLOGY: ENDOCRINOLOGY AND METABOLISM., US, (20120327), vol. 302, no. 12, doi:10.1152/ajpendo.00581.2011, ISSN 0193-1849, pages E1493 - E1501, XP055431777 [XD] 16 * the whole document, in particular the abstract * [Y] 17

DOI:   http://dx.doi.org/10.1152/ajpendo.00581.2011
 [XY]  - ANDREAS BORNØ ET AL, "Glucose and glycerol concentrations and their tracer enrichment measurements using liquid chromatography tandem mass spectrometry : LC-MS/MS measurements of glucose and glycerol", JOURNAL OF MASS SPECTROMETRY., GB, (20140929), vol. 49, no. 10, doi:10.1002/jms.3407, ISSN 1076-5174, pages 980 - 988, XP055431378 [X] 16 * the whole document, in particular the abstract * [Y] 17

DOI:   http://dx.doi.org/10.1002/jms.3407
 [Y]  - FREY ALEXANDER J ET AL, "LC-quadrupole/Orbitrap high-resolution mass spectrometry enables stable isotope-resolved simultaneous quantification and13C-isotopic labeling of acyl-coenzyme A thioesters", ANALYTICAL AND BIOANALYTICAL CHEMISTRY, SPRINGER, DE, vol. 408, no. 13, doi:10.1007/S00216-016-9448-5, ISSN 1618-2642, (20160311), pages 3651 - 3658, (20160311), XP035867745 [Y] 17 * the whole document, in particular the abstract *

DOI:   http://dx.doi.org/10.1007/s00216-016-9448-5
 [A]  - SUN D ET AL, "Quantification of the concentration and ^1^3C tracer enrichment of long-chain fatty acyl-coenzyme A in muscle by liquid chromatography/mass spectrometry", ANALYTICAL BIOCHEMISTRY, ELSEVIER, AMSTERDAM, NL, vol. 349, no. 1, doi:10.1016/J.AB.2005.10.006, ISSN 0003-2697, (20060201), pages 87 - 95, (20060201), XP024941974 [A] 1-17

DOI:   http://dx.doi.org/10.1016/j.ab.2005.10.006
 [A]  - ALAN G. MARSHALL ET AL, "High-Resolution Mass Spectrometers", ANNUAL REVIEW OF ANALYTICAL CHEMISTRY, US, (20080701), vol. 1, no. 1, doi:10.1146/annurev.anchem.1.031207.112945, ISSN 1936-1327, pages 579 - 599, XP055431756 [A] 1-17

DOI:   http://dx.doi.org/10.1146/annurev.anchem.1.031207.112945
 [T]  - MARTIN TRÖTZMÜLLER ET AL, "Determination of the Isotopic Enrichment of 13 C- and 2 H-Labeled Tracers of Glucose Using High-Resolution Mass Spectrometry: Application to Dual- and Triple-Tracer Studies", ANALYTICAL CHEMISTRY, US, (20171121), vol. 89, no. 22, doi:10.1021/acs.analchem.7b03134, ISSN 0003-2700, pages 12252 - 12260, XP055431788

DOI:   http://dx.doi.org/10.1021/acs.analchem.7b03134
by applicantWO2007031717
 WO2007106816
 US2013103337
    - TOFFOLO et al., Journal of Pediatric Endocrinology and Metabolism, (20080000), vol. 21, pages 31 - 45
    - BASU et al., American Journal of Physiology Endocrinology Metabolism, (20030000), vol. 248, pages E55 - E69
    - HAIDAR et al., American Journal of Physiology Endocrinology Metabolism, (20120000), vol. 302, pages E1493 - E1501
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