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Extract from the Register of European Patents

EP About this file: EP3333166

EP3333166 - PROCESS FOR THE PREPARATION OF N-[5-(3,5-DIFLUORO-BENZYL)-1H-INDAZOL-3-YL]-4-(4-METHYL-PIPERAZIN-1-YL)-2-(TETRAHYDRO-PYRAN-4-YLAMINO)-BENZAMIDE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  11.09.2020
Database last updated on 13.07.2024
FormerThe patent has been granted
Status updated on  04.10.2019
FormerGrant of patent is intended
Status updated on  30.09.2019
FormerExamination is in progress
Status updated on  05.08.2019
FormerGrant of patent is intended
Status updated on  24.04.2019
FormerExamination is in progress
Status updated on  30.11.2018
FormerRequest for examination was made
Status updated on  11.05.2018
Most recent event   Tooltip15.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 17.08.2022  [2022/33]
Applicant(s)For all designated states
NERVIANO MEDICAL SCIENCES S.R.L.
Viale Pasteur, 10
20014 Nerviano (MI) / IT
[2018/24]
Inventor(s)01 / BARBUGIAN, Natale Alvaro
Via Germana De Stael, 1
20158 Milan / IT
02 / FORINO, Romualdo
Via Del Caravaggio, 14
20144 Milan / IT
03 / FUMAGALLI, Tiziano
Via Dante 46
20069 Trezzano Rosa (MI) / IT
04 / ORSINI, Paolo
Via Padova, 5
20025 Legnano (MI) / IT
 [2018/24]
Application number, filing date17195806.922.05.2013
[2018/24]
Priority number, dateEP2012016913923.05.2012         Original published format: EP 12169139
[2018/24]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3333166
Date:13.06.2018
Language:EN
[2018/24]
Type: B1 Patent specification 
No.:EP3333166
Date:06.11.2019
Language:EN
[2019/45]
Search report(s)(Supplementary) European search report - dispatched on:EP26.03.2018
ClassificationIPC:C07D405/12, A61K31/496, A61P35/00
[2018/24]
CPC:
A61K31/496 (EP,US); C07D405/12 (EP,CN,RU,US); A61K31/497 (RU);
A61P35/00 (EP,US); C07D405/14 (US); C07B2200/13 (CN,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/24]
TitleGerman:VERFAHREN ZUR HERSTELLUNG VON N-[5-(3,5-DIFLUOR-BENZYL)-1H-INDAZOL-3-YL]-4-(4-METHYL-PIPERAZIN-1-YL)-2-(TETRAHYDRO-PYRAN-4-YLAMINO)-BENZAMID[2018/24]
English:PROCESS FOR THE PREPARATION OF N-[5-(3,5-DIFLUORO-BENZYL)-1H-INDAZOL-3-YL]-4-(4-METHYL-PIPERAZIN-1-YL)-2-(TETRAHYDRO-PYRAN-4-YLAMINO)-BENZAMIDE[2018/24]
French:PROCÉDÉ POUR LA PRÉPARATION DE N-[5-(3,5-DIFLUORO-BENZYL)-1H-INDAZOL-3-YL]-4-(4-MÉTHYL-PIPERAZIN-1-YL)-2-(TETRAHYDRO-PYRAN-4-YLAMINO)-BENZAMIDE[2018/24]
Examination procedure10.10.2017Examination requested  [2018/24]
10.10.2017Date on which the examining division has become responsible
25.07.2018Amendment by applicant (claims and/or description)
03.12.2018Despatch of a communication from the examining division (Time limit: M04)
07.12.2018Reply to a communication from the examining division
25.04.2019Communication of intention to grant the patent
30.07.2019Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
30.07.2019Fee for grant paid
30.07.2019Fee for publishing/printing paid
30.09.2019Information about intention to grant a patent
30.09.2019Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP13724270.7  / EP2855460
Divisional application(s)EP19188774.4  / EP3581571
Opposition(s)07.08.2020No opposition filed within time limit [2020/42]
Fees paidRenewal fee
10.10.2017Renewal fee patent year 03
10.10.2017Renewal fee patent year 04
10.10.2017Renewal fee patent year 05
29.05.2018Renewal fee patent year 06
28.05.2019Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU22.05.2013
AL06.11.2019
CY06.11.2019
CZ06.11.2019
DK06.11.2019
EE06.11.2019
FI06.11.2019
HR06.11.2019
LT06.11.2019
LV06.11.2019
MC06.11.2019
MK06.11.2019
MT06.11.2019
RS06.11.2019
SI06.11.2019
SK06.11.2019
SM06.11.2019
BG06.02.2020
NO06.02.2020
IS06.03.2020
PT06.03.2020
IE22.05.2020
LU22.05.2020
[2022/33]
Former [2022/28]HU22.05.2013
AL06.11.2019
CY06.11.2019
CZ06.11.2019
DK06.11.2019
EE06.11.2019
FI06.11.2019
HR06.11.2019
LT06.11.2019
LV06.11.2019
MC06.11.2019
MT06.11.2019
RS06.11.2019
SI06.11.2019
SK06.11.2019
SM06.11.2019
BG06.02.2020
NO06.02.2020
IS06.03.2020
PT06.03.2020
IE22.05.2020
LU22.05.2020
Former [2021/20]AL06.11.2019
CZ06.11.2019
DK06.11.2019
EE06.11.2019
FI06.11.2019
HR06.11.2019
LT06.11.2019
LV06.11.2019
MC06.11.2019
RS06.11.2019
SI06.11.2019
SK06.11.2019
SM06.11.2019
BG06.02.2020
NO06.02.2020
IS06.03.2020
PT06.03.2020
IE22.05.2020
LU22.05.2020
Former [2021/15]AL06.11.2019
CZ06.11.2019
DK06.11.2019
EE06.11.2019
FI06.11.2019
HR06.11.2019
LT06.11.2019
LV06.11.2019
MC06.11.2019
RS06.11.2019
SI06.11.2019
SK06.11.2019
SM06.11.2019
BG06.02.2020
NO06.02.2020
IS06.03.2020
PT06.03.2020
LU22.05.2020
Former [2021/12]AL06.11.2019
CZ06.11.2019
DK06.11.2019
EE06.11.2019
FI06.11.2019
HR06.11.2019
LT06.11.2019
LV06.11.2019
MC06.11.2019
RS06.11.2019
SI06.11.2019
SK06.11.2019
SM06.11.2019
BG06.02.2020
NO06.02.2020
IS06.03.2020
PT06.03.2020
Former [2020/51]AL06.11.2019
CZ06.11.2019
DK06.11.2019
EE06.11.2019
FI06.11.2019
HR06.11.2019
LT06.11.2019
LV06.11.2019
RS06.11.2019
SI06.11.2019
SK06.11.2019
SM06.11.2019
BG06.02.2020
NO06.02.2020
IS06.03.2020
PT06.03.2020
Former [2020/37]AL06.11.2019
CZ06.11.2019
DK06.11.2019
EE06.11.2019
FI06.11.2019
HR06.11.2019
LT06.11.2019
LV06.11.2019
RS06.11.2019
SK06.11.2019
SM06.11.2019
BG06.02.2020
NO06.02.2020
IS06.03.2020
PT06.03.2020
Former [2020/36]AL06.11.2019
CZ06.11.2019
DK06.11.2019
EE06.11.2019
FI06.11.2019
HR06.11.2019
LT06.11.2019
LV06.11.2019
RS06.11.2019
BG06.02.2020
NO06.02.2020
IS06.03.2020
PT06.03.2020
Former [2020/35]AL06.11.2019
CZ06.11.2019
FI06.11.2019
HR06.11.2019
LT06.11.2019
LV06.11.2019
RS06.11.2019
BG06.02.2020
NO06.02.2020
IS06.03.2020
PT06.03.2020
Former [2020/32]AL06.11.2019
FI06.11.2019
HR06.11.2019
LT06.11.2019
LV06.11.2019
RS06.11.2019
BG06.02.2020
NO06.02.2020
IS06.03.2020
PT06.03.2020
Former [2020/26]FI06.11.2019
HR06.11.2019
LT06.11.2019
LV06.11.2019
RS06.11.2019
BG06.02.2020
NO06.02.2020
IS06.03.2020
PT06.03.2020
Former [2020/24]FI06.11.2019
LT06.11.2019
LV06.11.2019
BG06.02.2020
NO06.02.2020
IS06.03.2020
PT06.03.2020
Former [2020/23]FI06.11.2019
LT06.11.2019
LV06.11.2019
BG06.02.2020
NO06.02.2020
PT06.03.2020
Former [2020/22]FI06.11.2019
LT06.11.2019
BG06.02.2020
NO06.02.2020
PT06.03.2020
Former [2020/21]NO06.02.2020
Documents cited:Search[AD]WO2009013126  (NERVIANO MEDICAL SCIENCES SRL [IT], et al) [AD] 1-15 * examples 2, 7 ** claims 1, 22-24, 31 *
by applicantWO2009013126
    - Current Opinion in Chemical Biology, (19990000), vol. 3, pages 459 - 465
    - Carcinogenesis, (20080000), vol. 29, pages 1087 - 1091
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.