| EP3342425 - MODIFIED OLIGONUCLEOTIDES FOR TELOMERASE INHIBITION [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 23.10.2020 Database last updated on 24.03.2026 | |
| Former | The patent has been granted Status updated on 15.11.2019 | ||
| Former | Grant of patent is intended Status updated on 01.07.2019 | ||
| Former | Examination is in progress Status updated on 25.01.2019 | ||
| Former | Request for examination was made Status updated on 04.01.2019 | ||
| Former | The application has been published Status updated on 01.06.2018 | Most recent event Tooltip | 23.10.2020 | No opposition filed within time limit | published on 25.11.2020 [2020/48] | Applicant(s) | For all designated states GERON CORPORATION 149 Commonwealth Drive Menlo Park, CA 94025 / US | [2018/27] | Inventor(s) | 01 /
GRYAZNOV, Sergei 138 West Bellevue Avenue San Mateo, CA 94402 / US | 02 /
PONGRACZ, Krisztina 6253 Fairlane Drive Oakland, CA 94611 / US | [2019/51] |
| Former [2018/27] | 01 /
GRYAZNOV, Sergei 138 West Bellevue Avenue San Mateo, CA California 94402 / US | ||
| 02 /
PONGRACZ, Krisztina 6253 Fairlane Drive Oakland, CA California 94611 / US | Representative(s) | Mewburn Ellis LLP Aurora Building Counterslip Bristol BS1 6BX / GB | [N/P] |
| Former [2019/51] | Mewburn Ellis LLP City Tower 40 Basinghall Street London EC2V 5DE / GB | ||
| Former [2018/27] | Wytenburg, Wilhelmus Johannes Mewburn Ellis LLP City Tower 40 Basinghall Street London EC2V 5DE / GB | Application number, filing date | 17200625.6 | 09.09.2004 | [2018/27] | Priority number, date | US20030501509P | 09.09.2003 Original published format: US 501509 P | [2018/27] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP3342425 | Date: | 04.07.2018 | Language: | EN | [2018/27] | Type: | B1 Patent specification | No.: | EP3342425 | Date: | 18.12.2019 | Language: | EN | [2019/51] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 29.05.2018 | Classification | IPC: | A61K47/54, C07H21/04, C12N5/00, C12N15/113, A61P35/00 | [2019/29] | CPC: |
A61K47/542 (EP,US);
C12N15/52 (KR);
C12N15/115 (US);
A61K47/543 (EP,US);
A61K47/544 (EP,US);
A61K47/554 (EP,US);
A61P35/00 (EP);
A61P35/02 (EP);
A61P43/00 (EP);
C07C233/18 (US);
C07H21/02 (EP,US);
C07H21/04 (EP,US);
C12N15/09 (KR);
C12N15/113 (EP,US);
C12N15/1137 (EP,US);
C12Y207/07049 (EP,US);
C12N2310/11 (EP,US);
C12N2310/113 (EP,US);
C12N2310/14 (US);
C12N2310/31 (US);
C12N2310/314 (US);
|
| Former IPC [2018/27] | A61K47/54, C07H21/04, C12N5/00, A61P35/00 | Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR [2019/06] |
| Former [2018/27] | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR | Title | German: | MODIFIZIERTE OLIGONUKLEOTIDE ZUR TELOMERASEHEMMUNG | [2018/27] | English: | MODIFIED OLIGONUCLEOTIDES FOR TELOMERASE INHIBITION | [2018/27] | French: | OLIGONUCLÉOTIDES MODIFIÉS POUR L'INHIBITION DE LA TÉLOMÉRASE | [2018/27] | Examination procedure | 21.12.2018 | Examination requested [2019/06] | 21.12.2018 | Date on which the examining division has become responsible | 23.01.2019 | Despatch of a communication from the examining division (Time limit: M04) | 17.05.2019 | Reply to a communication from the examining division | 02.07.2019 | Communication of intention to grant the patent | 06.11.2019 | Fee for grant paid | 06.11.2019 | Fee for publishing/printing paid | 06.11.2019 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP04783801.6 / EP1667522 | Divisional application(s) | EP19209408.4 / EP3682903 | Opposition(s) | 21.09.2020 | No opposition filed within time limit [2020/48] | Fees paid | Renewal fee | 29.01.2018 | Renewal fee patent year 03 | 29.01.2018 | Renewal fee patent year 04 | 29.01.2018 | Renewal fee patent year 05 | 29.01.2018 | Renewal fee patent year 06 | 29.01.2018 | Renewal fee patent year 07 | 29.01.2018 | Renewal fee patent year 08 | 29.01.2018 | Renewal fee patent year 09 | 29.01.2018 | Renewal fee patent year 10 | 29.01.2018 | Renewal fee patent year 11 | 29.01.2018 | Renewal fee patent year 12 | 29.01.2018 | Renewal fee patent year 13 | 29.01.2018 | Renewal fee patent year 14 | 11.09.2018 | Renewal fee patent year 15 | 13.09.2019 | Renewal fee patent year 16 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [A] WO9114696 (GILEAD SCIENCES INC et al.) | [A] US2003096776 (HANECAK RONNIE C et al.) | [A] US6608036 (GRYAZNOV SERGEI et al.) | [A] US2003138814 (GRYAZNOV SERGEI et al.) | [A] RAKESH KUMAR MISHRA ET AL: "IMPROVED LEISHMANICIDAL EFFECT OF PHOSPHOROTIOATE ANTISENSE OLIGONUCLEOTIDES BY LDL-MEDIATED DELIVERY", BIOCHIMICA ET BIOPHYSICA ACTA, ELSEVIER, NL, vol. 1264, no. 2, 1 January 1995 (1995-01-01), pages 229 - 237, XP008034024, ISSN: 0006-3002 | by applicant | US5411947 | US6448392 | US5420330 | US5763208 | US5416203 | WO9010448 | US6261836 | US5583016 | US6444650 | US6548298 | US6331399 | WO0118015 | WO9828442 | US5629154 | US5837453 | US5863726 | US4897355 | US4394448 | MICKLEFIELD: "Backbone modification of nucleic acids: synthesis, structure and therapeutic applications", CURR. MED. CHEM., vol. 8, no. 10, 2001, pages 1157 - 79, XP002365763 | LYER ET AL.: "Modified oligonucleotides--synthesis, properties and applications", CURR. OPIN. MOL THER., vol. 1, no. 3, 1999, pages 344 - 358, XP009103623 | NIELSEN, METHODS MOL. BIOL., vol. 208, 2002, pages 3 - 26 | PETERSEN; WENGEL, TRENDS BIOTECHNOL., vol. 21, no. 2, 2003, pages 74 - 81 | ECKSTEIN, ANTISENSE NUCLEIC ACID DRUG DEV., vol. 10, no. 2, 2000, pages 117 - 21 | THIVIYANATHAN ET AL., BIOCHEMISTRY, vol. 41, no. 3, 2002, pages 827 - 38 | GRYAZNOV, BIOCHEM. BIOPHYS. ACTA, vol. 1489, no. 1, 1999, pages 131 - 40 | PRUZAN, NUCLEIC ACIDS RES., vol. 30, no. 2, 2002, pages 559 - 68 | GRYAZNOV ET AL., NUCLEOSIDES NUCLEOTIDES NUCLEIC ACIDS, vol. 20, no. 4-7, 2001, pages 401 - 10 | HERBERT ET AL., ONCOGENE, vol. 21, no. 4, 2002, pages 638 - 42 | GRYAZNOV; LETSINGER, NUCLEIC ACIDS RESEARCH, vol. 20, 1992, pages 3403 - 3409 | CHEN ET AL., NUCLEIC ACIDS RESEARCH, vol. 23, 1995, pages 2661 - 2668 | GRYAZNOV ET AL., PROC, NATL. ACAD. SCI., vol. 92, 1995, pages 5798 - 5802 | SKORSKI ET AL., PROC. NATL. ACAD. SCI., vol. 94, 1997, pages 3966 - 3971 | GRYAZNOV ET AL., NUCLEIC ACIDS RESEARCH, vol. 24, 1996, pages 1508 - 1514 | PEDROSO DE LIMA ET AL., CURR MED CHEM, vol. 10, no. 14, 2003, pages 1221 - 1231 | MILLER, CURR MED CHEM., vol. 10, no. 14, 2003, pages 1195 - 211 | GRYAZNOV; LLOYD, NUCLEIC ACIDS RESEARCH, vol. 21, 1993, pages 5909 - 5915 | GERSTER ET AL., ANALYTICAL BIOCHEMISTRY, vol. 262, 1998, pages 177 - 184 | BENNETT ET AL., MOL. PHARMACOL., vol. 41, 1992, pages 1023 - 1033 | MANOHARAN ET AL., ANTISENSE AND NUCLEIC ACID DRUG DEV., vol. 12, 2002, pages 103 - 128 | FIEDLER ET AL., LANGENBECK'S ARCH. SURG., vol. 383, 1998, pages 269 - 275 | BLACKBURN, ANN. REV. BIOCHEM., vol. 61, 1992, pages 113 - 129 | ONCOGENE, vol. 21, January 2002 (2002-01-01) | LICHSTEINER ET AL., ANNALS NEW YORK ACAD. SCI., vol. 886, 1999, pages 1 - 11 | VAN JANTA-LIPINSKI, NUCLEOSIDES NUCLEOTIDES, vol. 18, no. 6-7, 1999, pages 1719 - 20 | GRYAZNOV ET AL., NUCLEOSIDES NUCLEOTIDES NUCLEIC ACIDS, vol. 20, 2001, pages 401 - 410 | PRUZAN ET AL., NUCLEIC ACIDS RESEARCH, vol. 30, no. 2, 2002, pages 559 - 568 | ASAI ET AL., CANCER RESEARCH, vol. 63, 2003, pages 3931 - 3939 | FENG, SCIENCE, vol. 269, no. 5228, 1995, pages 1236 - 1241 | KOMBERG; BAKER: "DNA Replication", 1992, FREEMAN | SCHEIT: "Nucleotide Analogs", 1980, JOHN WILEY | UHLMANN; PEYMAN, CHEMICAL REVIEWS, vol. 90, 1990, pages 543 - 584 | TETRAHEDRON, vol. 48, 1992, pages 223 - 2311 | "Oligonucleotide Synthesis: A Practical Approach", 1984, IRL PRESS | AMARNATH; BROOM, CHEMICAL REVIEWS, vol. 77, 1977, pages 183 - 217 | PON ET AL., BIOTECHNIQUES, vol. 6, 1988, pages 768 - 775 | OHTSUKA ET AL., NUCLEIC ACIDS RESEARCH, vol. 10, 1982, pages 6553 - 6570 | "oligonucleotides and Analogues: A Practical Approach", 1991, IRL PRESS | GREENE; WUTS: "Protective Groups in Organic Synthesis", 1991, JOHN WILEY & SONS | "Synthesis and Applications of DNA and RNA", 1987, ACADEMIC PRESS | CHEN ET AL., CELL, vol. 100, 2000, pages 503 - 514 | KIM, PROC, NATT. ACAD. SCI., vol. 98, no. 14, 2001, pages 7982 - 7987 | PRUZAN, NUCL. ACIDS RESEARCH, vol. 30, 2002, pages 559 - 568 | MCCURDY ET AL., TETRAHEDRON LETTERS, vol. 38, 1997, pages 207 - 210 | PONGRACZ; GRYAZNOV, TETRAHEDRON LETTERS, vol. 49, 1999, pages 7661 - 7664 | MISHRA ET AL., BIOCHEMICA ET BIOPHYSICS ACTA, vol. 1264, 1995, pages 229 - 237 | SHEA, NUCLEIC ACIDS RES., vol. 18, 1990, pages 3777 - 3783 | RUMP ET AL., BIOCONJ. CHEM., vol. 9, 1998, pages 341 - 349 | KUPIHAR ET AL., BIOORGANIC AND MEDICINAL CHEMISTRY, vol. 9, 2001, pages 1241 - 1247 | KIM ET AL., SCIENCE, vol. 266, 1997, pages 2011 | WEINRICH ET AL., NATURE GENETICS, vol. 17, 1997, pages 498 | SCORSKI ET AL., PROC. NATL. ACAD. SCI. USA, vol. 94, 1997, pages 3966 - 3971 | DAMM ET AL., EMBO J., vol. 20, 2001, pages 6958 - 6968 | PONGRACZ; GRYAZNOV, TETRAHEDRON LETTERS, vol. 49, 1999, pages 7661 - 7664 |