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Extract from the Register of European Patents

EP About this file: EP3464562

EP3464562 - PROCESS FOR GENERATION, IDENTIFICATION AND ISOLATION OF HUMAN PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES AND CARDIOMYOCYTE SUBPOPULATIONS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  22.07.2022
Database last updated on 03.10.2024
FormerThe patent has been granted
Status updated on  13.08.2021
FormerGrant of patent is intended
Status updated on  16.04.2021
FormerExamination is in progress
Status updated on  29.01.2020
FormerRequest for examination was made
Status updated on  08.03.2019
FormerThe international publication has been made
Status updated on  08.12.2017
Formerunknown
Status updated on  16.06.2017
Most recent event   Tooltip13.09.2024Lapse of the patent in a contracting state
New state(s): MT		published on 16.10.2024 [2024/42]
Applicant(s)For all designated states
Miltenyi Biotec B.V. & Co. KG
Friedrich-Ebert-Strasse 68
51429 Bergisch Gladbach / DE
[2019/46]
Former [2019/15]For all designated states
Miltenyi Biotec GmbH
Friedrich-Ebert-Strasse 68
51429 Bergisch Gladbach / DE
Inventor(s)01 / BECKER, Kristin
Moitzfeld 73
51429 Bergisch Gladbach / DE
02 / ECKARDT, Dominik
Diakonissenweg 29
51429 Bergisch Gladbach / DE
03 / BOSIO, Andreas
Hanfweg 17
50939 Köln / DE
 [2021/37]
Former [2020/29]01 / BECKER, Kristin
Moitzfeld 73
51429 Bergisch Gladbach / DE
02 / ECKARDT, Dominik
Diakonissenweg 29
51429 Bergisch Gadbach / DE
03 / BOSIO, Andreas
Hanfweg 17
50939 Köln / DE
Former [2019/15]01 / NOACK, Kristin
Moitzfeld 73
51429 Bergisch Gladbach / DE
02 / ECKARDT, Dominik
Diakonissenweg 29
51429 Bergisch Gadbach / DE
03 / BOSIO, Andreas
Hanfweg 17
50939 Köln / DE
Representative(s)Biervert, Christian
c/o Miltenyi Biotec B.V. & Co. KG
Corporate Legal Department
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach / DE
[2021/37]
Former [2019/15]Biervert, Christian
Miltenyi Biotec GmbH
Corporate Legal Department
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach / DE
Application number, filing date17728118.530.05.2017
[2019/15]
WO2017EP63047
Priority number, dateEP2016017252801.06.2016         Original published format: EP 16172528
[2019/15]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017207576
Date:07.12.2017
Language:EN
[2017/49]
Type: A1 Application with search report 
No.:EP3464562
Date:10.04.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 07.12.2017 takes the place of the publication of the European patent application.
[2019/15]
Type: B1 Patent specification 
No.:EP3464562
Date:15.09.2021
Language:EN
[2021/37]
Search report(s)International search report - published on:EP07.12.2017
ClassificationIPC:C12N5/077, C12N5/0735, C12N5/074, A61P9/00
[2021/17]
CPC:
C12N5/0657 (EP,US); A61K35/34 (US); A61P9/00 (EP);
G01N33/5005 (US); G01N33/582 (US); C12N2500/98 (EP);
C12N2501/115 (EP,US); C12N2501/155 (EP,US); C12N2501/16 (EP,US);
C12N2501/415 (EP); C12N2501/727 (EP); C12N2501/999 (US);
C12N2506/02 (EP,US); C12N2506/45 (EP,US) (-)
Former IPC [2019/15]C12N5/077, C12N5/0735, C12N5/074
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/15]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:VERFAHREN ZUR ERZEUGUNG, IDENTIFIZIERUNG UND ISOLIERUNG VON MENSCHLICHEN PLURIPOTENTEN STAMMZELLEN AUS KARDIOMYOZYTEN UND KARDIOMYOZYT-SUBPOPULATIONEN[2019/15]
English:PROCESS FOR GENERATION, IDENTIFICATION AND ISOLATION OF HUMAN PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES AND CARDIOMYOCYTE SUBPOPULATIONS[2019/15]
French:PROCÉDÉ POUR LA GÉNÉRATION, L'IDENTIFICATION ET L'ISOLEMENT DE CARDIOMYOCYTES ISSUS DE CELLULES SOUCHES PLURIPOTENTES HUMAINES ET DES SOUS-POPULATIONS DE CARDIOMYOCYTES[2021/17]
Former [2019/15]PROCÉDÉ DE PRODUCTION, D'IDENTIFICATION ET D'ISOLEMENT DE CARDIOMYOCYTES DÉRIVÉS DE CELLULES SOUCHES PLURIPOTENTES HUMAINES ET SOUS-POPULATIONS DE CARDIOMYOCYTES
Entry into regional phase17.12.2018National basic fee paid 
17.12.2018Designation fee(s) paid 
17.12.2018Examination fee paid 
Examination procedure17.12.2018Examination requested  [2019/15]
17.12.2018Date on which the examining division has become responsible
05.07.2019Amendment by applicant (claims and/or description)
03.02.2020Despatch of a communication from the examining division (Time limit: M04)
02.06.2020Reply to a communication from the examining division
23.04.2021Communication of intention to grant the patent
05.08.2021Fee for grant paid
05.08.2021Fee for publishing/printing paid
05.08.2021Receipt of the translation of the claim(s)
Opposition(s)16.06.2022No opposition filed within time limit [2022/34]
Fees paidRenewal fee
17.12.2018Renewal fee patent year 03
31.03.2020Renewal fee patent year 04
13.05.2021Renewal fee patent year 05
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU30.05.2017
AL15.09.2021
AT15.09.2021
CY15.09.2021
CZ15.09.2021
DK15.09.2021
EE15.09.2021
FI15.09.2021
HR15.09.2021
LT15.09.2021
LV15.09.2021
MC15.09.2021
MK15.09.2021
MT15.09.2021
PL15.09.2021
RO15.09.2021
RS15.09.2021
SE15.09.2021
SI15.09.2021
SK15.09.2021
SM15.09.2021
BG15.12.2021
NO15.12.2021
GR16.12.2021
IS15.01.2022
PT17.01.2022
IE30.05.2022
LU30.05.2022
[2024/42]
Former [2024/22]HU30.05.2017
AL15.09.2021
AT15.09.2021
CY15.09.2021
CZ15.09.2021
DK15.09.2021
EE15.09.2021
FI15.09.2021
HR15.09.2021
LT15.09.2021
LV15.09.2021
MC15.09.2021
MK15.09.2021
PL15.09.2021
RO15.09.2021
RS15.09.2021
SE15.09.2021
SI15.09.2021
SK15.09.2021
SM15.09.2021
BG15.12.2021
NO15.12.2021
GR16.12.2021
IS15.01.2022
PT17.01.2022
IE30.05.2022
LU30.05.2022
Former [2024/20]HU30.05.2017
AL15.09.2021
AT15.09.2021
CY15.09.2021
CZ15.09.2021
DK15.09.2021
EE15.09.2021
FI15.09.2021
HR15.09.2021
LT15.09.2021
LV15.09.2021
MC15.09.2021
PL15.09.2021
RO15.09.2021
RS15.09.2021
SE15.09.2021
SI15.09.2021
SK15.09.2021
SM15.09.2021
BG15.12.2021
NO15.12.2021
GR16.12.2021
IS15.01.2022
PT17.01.2022
IE30.05.2022
LU30.05.2022
Former [2024/18]HU30.05.2017
AL15.09.2021
AT15.09.2021
CZ15.09.2021
DK15.09.2021
EE15.09.2021
FI15.09.2021
HR15.09.2021
LT15.09.2021
LV15.09.2021
MC15.09.2021
PL15.09.2021
RO15.09.2021
RS15.09.2021
SE15.09.2021
SI15.09.2021
SK15.09.2021
SM15.09.2021
BG15.12.2021
NO15.12.2021
GR16.12.2021
IS15.01.2022
PT17.01.2022
IE30.05.2022
LU30.05.2022
Former [2023/20]AL15.09.2021
AT15.09.2021
CZ15.09.2021
DK15.09.2021
EE15.09.2021
FI15.09.2021
HR15.09.2021
LT15.09.2021
LV15.09.2021
MC15.09.2021
PL15.09.2021
RO15.09.2021
RS15.09.2021
SE15.09.2021
SI15.09.2021
SK15.09.2021
SM15.09.2021
BG15.12.2021
NO15.12.2021
GR16.12.2021
IS15.01.2022
PT17.01.2022
IE30.05.2022
LU30.05.2022
Former [2023/08]AL15.09.2021
AT15.09.2021
CZ15.09.2021
DK15.09.2021
EE15.09.2021
FI15.09.2021
HR15.09.2021
LT15.09.2021
LV15.09.2021
MC15.09.2021
PL15.09.2021
RO15.09.2021
RS15.09.2021
SE15.09.2021
SI15.09.2021
SK15.09.2021
SM15.09.2021
BG15.12.2021
NO15.12.2021
GR16.12.2021
IS15.01.2022
PT17.01.2022
LU30.05.2022
Former [2023/06]AL15.09.2021
AT15.09.2021
CZ15.09.2021
DK15.09.2021
EE15.09.2021
FI15.09.2021
HR15.09.2021
LT15.09.2021
LV15.09.2021
MC15.09.2021
PL15.09.2021
RO15.09.2021
RS15.09.2021
SE15.09.2021
SI15.09.2021
SK15.09.2021
SM15.09.2021
BG15.12.2021
NO15.12.2021
GR16.12.2021
IS15.01.2022
PT17.01.2022
Former [2022/36]AL15.09.2021
AT15.09.2021
CZ15.09.2021
DK15.09.2021
EE15.09.2021
FI15.09.2021
HR15.09.2021
LT15.09.2021
LV15.09.2021
PL15.09.2021
RO15.09.2021
RS15.09.2021
SE15.09.2021
SI15.09.2021
SK15.09.2021
SM15.09.2021
BG15.12.2021
NO15.12.2021
GR16.12.2021
IS15.01.2022
PT17.01.2022
Former [2022/29]AL15.09.2021
AT15.09.2021
CZ15.09.2021
EE15.09.2021
FI15.09.2021
HR15.09.2021
LT15.09.2021
LV15.09.2021
PL15.09.2021
RO15.09.2021
RS15.09.2021
SE15.09.2021
SK15.09.2021
SM15.09.2021
BG15.12.2021
NO15.12.2021
GR16.12.2021
IS15.01.2022
PT17.01.2022
Former [2022/25]AT15.09.2021
CZ15.09.2021
EE15.09.2021
FI15.09.2021
HR15.09.2021
LT15.09.2021
LV15.09.2021
PL15.09.2021
RO15.09.2021
RS15.09.2021
SE15.09.2021
SK15.09.2021
SM15.09.2021
BG15.12.2021
NO15.12.2021
GR16.12.2021
IS15.01.2022
PT17.01.2022
Former [2022/24]AT15.09.2021
CZ15.09.2021
EE15.09.2021
FI15.09.2021
HR15.09.2021
LT15.09.2021
LV15.09.2021
PL15.09.2021
RO15.09.2021
RS15.09.2021
SE15.09.2021
SK15.09.2021
BG15.12.2021
NO15.12.2021
GR16.12.2021
IS15.01.2022
PT17.01.2022
Former [2022/23]AT15.09.2021
CZ15.09.2021
EE15.09.2021
FI15.09.2021
HR15.09.2021
LT15.09.2021
LV15.09.2021
PL15.09.2021
RS15.09.2021
SE15.09.2021
SK15.09.2021
BG15.12.2021
NO15.12.2021
GR16.12.2021
PT17.01.2022
Former [2022/21]AT15.09.2021
FI15.09.2021
HR15.09.2021
LT15.09.2021
LV15.09.2021
RS15.09.2021
SE15.09.2021
BG15.12.2021
NO15.12.2021
GR16.12.2021
Former [2022/10]FI15.09.2021
HR15.09.2021
LT15.09.2021
LV15.09.2021
RS15.09.2021
SE15.09.2021
BG15.12.2021
NO15.12.2021
GR16.12.2021
Former [2022/09]FI15.09.2021
LT15.09.2021
RS15.09.2021
SE15.09.2021
BG15.12.2021
NO15.12.2021
Former [2022/08]FI15.09.2021
LT15.09.2021
SE15.09.2021
BG15.12.2021
NO15.12.2021
Former [2022/07]LT15.09.2021
NO15.12.2021
Cited inInternational search[XDYI]WO2012135253  (GERON CORP [US], et al) [XD] 14 * the whole document * * page 58 - page 61; examples VI-VII * * claim 50 * [Y] 2,6-13,15 [I] 1,3-5;
 [XY]WO2012133954  (UNIV KYOTO [JP], et al) [X] 14 * the whole document * * claims 1-12 * [Y] 6-12,15;
 [XY]WO2014014119  (UNIV KYOTO [JP]) [X] 14 * the whole document * * claims 1-15 * [Y] 6-12,15;
 [XY]  - DUBOIS NICOLE C ET AL, "SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells", NATURE BIOTECHNOLOGY, GALE GROUP INC, US, vol. 29, no. 11, doi:10.1038/NBT.2005, ISSN 1087-0156, (20111101), pages 1011 - 1019, (20111023), XP009167979 [X] 14 * the whole document * * page 1016, paragraph 2; figure 7 * [Y] 2

DOI:   http://dx.doi.org/10.1038/nbt.2005
 [XY]  - CHUNHUI XU, "Differentiation and enrichment of cardiomyocytes from human pluripotent stem cells", JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, ACADEMIC PRESS, GB, vol. 52, no. 6, doi:10.1016/J.YJMCC.2012.03.012, ISSN 0022-2828, (20120320), pages 1203 - 1212, (20120330), XP028482910 [X] 14 * the whole document * [Y] 2,6-13,15

DOI:   http://dx.doi.org/10.1016/j.yjmcc.2012.03.012
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 EP20140167201
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.