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EP About this file: EP3452985

EP3452985 - NUCLEOLAR STRUCTURE EVALUATION AND MANIPULATION [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  31.05.2024
Database last updated on 03.10.2024
FormerThe patent has been granted
Status updated on  23.06.2023
FormerGrant of patent is intended
Status updated on  08.02.2023
FormerExamination is in progress
Status updated on  05.12.2022
FormerGrant of patent is intended
Status updated on  01.05.2022
FormerExamination is in progress
Status updated on  30.04.2020
FormerRequest for examination was made
Status updated on  08.01.2020
FormerExamination is in progress
Status updated on  20.09.2019
FormerRequest for examination was made
Status updated on  08.02.2019
FormerThe international publication has been made
Status updated on  10.11.2017
Formerunknown
Status updated on  27.06.2017
Most recent event   Tooltip31.05.2024No opposition filed within time limitpublished on 03.07.2024  [2024/27]
Applicant(s)For all designated states
Université Libre de Bruxelles
Avenue Franklin Roosevelt 50
1050 Brussels / BE
[2019/11]
Inventor(s)01 / LAFONTAINE, Denis
Avenue Léon Fournet, 9-204
1342 Limelette / BE
02 / DE VLEESCHOUWER, Christophe
Esplanade du Bon Air, 10
5020 Vedrin / BE
03 / NICOLAS, Emilien
Rue du Moulin, 70B
boîte 3
6740 Etalle / BE
04 / PARISOT, Pascaline
Place Verte 60/201
1348 Louvain-la-Neuve / BE
 [2019/11]
Representative(s)De Clercq & Partners
Edgard Gevaertdreef 10a
9830 Sint-Martens-Latem / BE
[2019/11]
Application number, filing date17730378.103.05.2017
[2019/11]
WO2017EP60532
Priority number, dateEP2016016808703.05.2016         Original published format: EP 16168087
[2019/11]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2017191187
Date:09.11.2017
Language:EN
[2017/45]
Type: A2 Application without search report 
No.:EP3452985
Date:13.03.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 09.11.2017 takes the place of the publication of the European patent application.
[2019/11]
Type: B1 Patent specification 
No.:EP3452985
Date:26.07.2023
Language:EN
[2023/30]
Search report(s)International search report - published on:EP04.01.2018
(Supplementary) European search report - dispatched on:EP06.05.2020
ClassificationIPC:G06T7/00, G01N33/50
[2019/11]
CPC:
G06T7/0012 (EP); G01N33/5026 (EP); G01N33/6875 (EP);
G06T2207/10056 (EP); G06T2207/20036 (EP); G06T2207/20076 (EP);
G06T2207/30024 (EP) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/11]  
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:BEWERTUNG UND MANIPULATION VON NUKLEOLARER STRUKTUR[2019/11]
English:NUCLEOLAR STRUCTURE EVALUATION AND MANIPULATION[2019/11]
French:ÉVALUATION ET MANIPULATION DE STRUCTURE NUCLÉOLAIRE[2019/11]
Entry into regional phase28.11.2018National basic fee paid 
28.11.2018Designation fee(s) paid 
28.11.2018Examination fee paid 
Examination procedure28.11.2018Examination requested  [2019/11]
28.11.2018Date on which the examining division has become responsible
20.06.2019Amendment by applicant (claims and/or description)
06.05.2020Despatch of a communication from the examining division to which search results under Rule 164(2) EPC are annexed (Time limit: M04) [2020/23]
06.05.2020Despatch of a communication from the examining division (Time limit: M04)
14.09.2020Reply to a communication from the examining division
13.01.2021Despatch of a communication from the examining division (Time limit: M04)
25.05.2021Reply to a communication from the examining division
08.03.2022Cancellation of oral proceeding that was planned for 10.03.2022
10.03.2022Date of oral proceedings (cancelled)
02.05.2022Communication of intention to grant the patent
05.10.2022Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time
05.12.2022Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
09.02.2023Communication of intention to grant the patent
16.06.2023Fee for grant paid
16.06.2023Fee for publishing/printing paid
16.06.2023Receipt of the translation of the claim(s)
Opposition(s)29.04.2024No opposition filed within time limit [2024/27]
Request for further processing for:The application is deemed to be withdrawn due to failure to fulfill actions required for granting the patent
05.12.2022Request for further processing filed
05.12.2022Full payment received (date of receipt of payment)
Request granted
09.12.2022Decision despatched
Fees paidRenewal fee
23.05.2019Renewal fee patent year 03
22.05.2020Renewal fee patent year 04
18.05.2021Renewal fee patent year 05
25.05.2022Renewal fee patent year 06
26.05.2023Renewal fee patent year 07
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCZ26.07.2023
HR26.07.2023
PL26.07.2023
RO26.07.2023
RS26.07.2023
SK26.07.2023
SM26.07.2023
NO26.10.2023
GR27.10.2023
IS26.11.2023
[2024/23]
Former [2024/20]HR26.07.2023
PL26.07.2023
RS26.07.2023
SM26.07.2023
NO26.10.2023
GR27.10.2023
IS26.11.2023
Former [2024/10]HR26.07.2023
PL26.07.2023
RS26.07.2023
NO26.10.2023
GR27.10.2023
IS26.11.2023
Former [2024/09]NO26.10.2023
GR27.10.2023
IS26.11.2023
Former [2024/08]NO26.10.2023
GR27.10.2023
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DOI:   http://dx.doi.org/10.1083/jcb.201005117
 [X]  - T. TENG ET AL, "Loss of Tumor Suppressor RPL5/RPL11 Does Not Induce Cell Cycle Arrest but Impedes Proliferation Due to Reduced Ribosome Content and Translation Capacity", MOLECULAR AND CELLULAR BIOLOGY., US, (20130923), vol. 33, no. 23, doi:10.1128/MCB.01174-13, ISSN 0270-7306, pages 4660 - 4671, XP055402814 [X] 1,23 * abstract *

DOI:   http://dx.doi.org/10.1128/MCB.01174-13
 [X]  - GOLOMB LIOR ET AL, "p53 and ribosome biogenesis stress: The essentials", FEBS LETTERS, ELSEVIER, AMSTERDAM, NL, (20140418), vol. 588, no. 16, doi:10.1016/J.FEBSLET.2014.04.014, ISSN 0014-5793, pages 2571 - 2579, XP029008738 [X] 1,23 * see section 2;; table 1 *

DOI:   http://dx.doi.org/10.1016/j.febslet.2014.04.014
 [I]  - BURSAC SLADANA ET AL, "Activation of the tumor suppressor p53 upon impairment of ribosome biogenesis", BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE, (20131026), vol. 1842, no. 6, doi:10.1016/J.BBADIS.2013.08.014, ISSN 0925-4439, pages 817 - 830, XP028599496 [I] 1,23 * figure 2 *

DOI:   http://dx.doi.org/10.1016/j.bbadis.2013.08.014
 [X]  - TAKAO KURODA ET AL, "RNA content in the nucleolus alters p53 acetylation via MYBBP1A : MYBBP1A transduces nucleolar stress signal to p53", EMBO JOURNAL., GB, (20110316), vol. 30, no. 6, doi:10.1038/emboj.2011.23, ISSN 0261-4189, pages 1054 - 1066, XP055402775 [X] 1,23 * abstract *

DOI:   http://dx.doi.org/10.1038/emboj.2011.23
 [X]  - HANNA T. GAZDA ET AL, "Ribosomal Protein L5 and L11 Mutations Are Associated with Cleft Palate and Abnormal Thumbs in Diamond-Blackfan Anemia Patients", AMERICAN JOURNAL OF HUMAN GENETICS, US, (20081201), vol. 83, no. 6, doi:10.1016/j.ajhg.2008.11.004, ISSN 0002-9297, pages 769 - 780, XP055402659 [X] 1,23 * abstract *

DOI:   http://dx.doi.org/10.1016/j.ajhg.2008.11.004
 [A]  - HAITONG SU ET AL, "Identification of Novel Markers That Demarcate the Nucleolus during Severe Stress and Chemotherapeutic Treatment", PLOS ONE, (20131106), vol. 8, no. 11, doi:10.1371/journal.pone.0080237, page e80237, XP055402751 [A] 1,23 * abstract *

DOI:   http://dx.doi.org/10.1371/journal.pone.0080237
 [T]  - EMILIEN NICOLAS ET AL, "Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress", NATURE COMMUNICATIONS, (20160606), vol. 7, doi:10.1038/ncomms11390, page 11390, XP055402736

DOI:   http://dx.doi.org/10.1038/ncomms11390
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