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EP3469083
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| EP3469083 - COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) [Right-click to bookmark this link] | Status | Examination is in progress Status updated on 31.07.2020 Database last updated on 14.06.2024 | |
| Former | Request for examination was made Status updated on 15.03.2019 | ||
| Former | The international publication has been made Status updated on 16.12.2017 | ||
| Former | unknown Status updated on 13.07.2017 | Most recent event Tooltip | 05.01.2024 | Change - applicant | published on 07.02.2024 [2024/06] | Applicant(s) | For all designated states Alnylam Pharmaceuticals, Inc. 675 West Kendall Street Henri A. Termeer Square Cambridge, MA 02142 / US | [2024/06] |
| Former [2019/16] | For all designated states Alnylam Pharmaceuticals, Inc. 300 Third Street, 3rd Floor Cambridge, MA 02142 / US | Inventor(s) | 01 /
NAJAFIAN, Nader 300 Third Street 3rd Floor Cambridge MA 02142 / US | 02 /
KIM, Jae 300 Third Street 3rd Floor Cambridge MA 02142 / US | 03 /
VAROGLU, Mustafa 300 Third Street 3rd Floor Cambridge MA 02142 / US | 04 /
ROBBIE, Gabriel 300 Third Street 3rd Floor Cambridge MA 02142 / US | [2019/16] | Representative(s) | Hoffmann Eitle Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München / DE | [2019/16] | Application number, filing date | 17734891.9 | 09.06.2017 | [2019/16] | WO2017US36775 | Priority number, date | US201662348564P | 10.06.2016 Original published format: US 201662348564 P | US201662429448P | 02.12.2016 Original published format: US 201662429448 P | [2019/16] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2017214518 | Date: | 14.12.2017 | Language: | EN | [2017/50] | Type: | A1 Application with search report | No.: | EP3469083 | Date: | 17.04.2019 | Language: | EN | The application published by WIPO in one of the EPO official languages on 14.12.2017 takes the place of the publication of the European patent application. | [2019/16] | Search report(s) | International search report - published on: | EP | 14.12.2017 | Classification | IPC: | C12N15/113, A61K31/713, A61K39/395, C07H21/00 | [2019/16] | CPC: |
C12N15/113 (EP,US);
A61K39/3955 (US);
A61P13/02 (EP,US);
A61P43/00 (EP);
C07K16/18 (US);
A61K2039/545 (US);
C12N2310/14 (EP,US);
C12N2310/315 (EP,US);
C12N2310/321 (US);
C12N2310/322 (US);
C12N2310/346 (EP,US);
C12N2310/351 (EP,US);
| C-Set: |
C12N2310/321, C12N2310/3521 (EP,US);
C12N2310/322, C12N2310/3533 (US,EP) | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2019/16] | Title | German: | GEGEN KOMPLEMENTKOMPONENTE C5 GERICHTETE IRNA-ZUSAMMENSETZUNGEN UND VERFAHREN ZUR VERWENDUNG DAVON ZUR BEHANDLUNG VON PAROXYSMALER NÄCHTLICHER HÄMOGLOBINURIE (PNH) | [2019/16] | English: | COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) | [2019/16] | French: | COMPOSITIONS D'ARNI DU COMPOSANT C5 DU COMPLÉMENT ET LEURS MÉTHODES D'UTILISATION POUR TRAITER L'HÉMOGLOBINURIE PAROXYSTIQUE NOCTURNE (HPN) | [2019/16] | Entry into regional phase | 09.01.2019 | National basic fee paid | 09.01.2019 | Designation fee(s) paid | 09.01.2019 | Examination fee paid | Examination procedure | 09.01.2019 | Amendment by applicant (claims and/or description) | 09.01.2019 | Examination requested [2019/16] | 09.01.2019 | Date on which the examining division has become responsible | 04.08.2020 | Despatch of a communication from the examining division (Time limit: M08) | 10.05.2021 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 16.07.2021 | Reply to a communication from the examining division | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the examination report | 16.07.2021 | Request for further processing filed | 16.07.2021 | Full payment received (date of receipt of payment) Request granted | 26.07.2021 | Decision despatched | Fees paid | Renewal fee | 27.06.2019 | Renewal fee patent year 03 | 29.06.2020 | Renewal fee patent year 04 | 28.06.2021 | Renewal fee patent year 05 | 27.06.2022 | Renewal fee patent year 06 | 27.06.2023 | Renewal fee patent year 07 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [AD]WO2009073809 (ALNYLAM PHARMACEUTICALS INC [US], et al) [AD] 42-46 * the whole document *; | [I]WO2014160129 (ALNYLAM PHARMACEUTICALS INC [US]) [I] 1-49 * the whole document *; | [I]WO2016040589 (ALNYLAM PHARMACEUTICALS INC [US]) [I] 1-49 * the whole document *; | [I]WO2016044419 (ALNYLAM PHARMACEUTICALS INC [US]) [I] 1-49 * the whole document *; | [XP]WO2016201301 (ALNYLAM PHARMACEUTICALS INC [US]) [XP] 1-49* the whole document *; | [A] - A. Hill ET AL, "ALN-CC5 PHASE 1 STUDY DESIGN Objectives Complement Assay Benchmarks from Select Published Literature ALN-CC5 PHASE 1 PRELIMINARY STUDY RESULTS* Demographics and Baseline Characteristics Safety and Tolerability* Part A: Single Ascending Dose (SAD) Part B: Multiple Ascending Dose (MAD)", (20151201), URL: https://s3.amazonaws.com/academia.edu.documents/44825766/ASH-2015_CC5_Hill_Poster_010615.pdf?AWSAccessKeyId=AKIAIWOWYYGZ2Y53UL3A&Expires=1503481629&Signature=behBRCmPpcO3Nbv7%2BZE0UHvjWIk%3D&response-content-disposition=inline%3B%20filename%3DA_Subcutaneously_Administered_Investigat.pdf, (20170823), XP055400561 [A] 1-49 * the whole document * | by applicant | US564562 | US3687808 | US4469863 | US4476301 | US4587044 | US4605735 | US4667025 | US4683202 | WO8804924 | US4762779 | US4789737 | US4824941 | US4828979 | US4835263 | US4837028 | US4845205 | US4876335 | US4897355 | US4904582 | US4948882 | US4958013 | US4981957 | US5023243 | US5032401 | US5034506 | WO9116024 | US5082830 | US5109124 | US5112963 | US5118800 | US5118802 | US5134066 | US5138045 | US5139941 | US5166315 | US5171678 | US5175273 | US5177195 | US5185444 | US5188897 | US5214134 | US5214136 | US5216141 | US5218105 | US5235033 | US5245022 | US5252479 | US5254469 | US5258506 | US5262536 | US5264423 | US5264564 | WO9324641 | WO9324640 | US5272250 | US5276019 | WO9400569 | US5278302 | US5283185 | WO9402595 | US5286717 | US5292873 | US5317098 | US5319080 | WO9412649 | US5321131 | WO9413788 | US5359044 | US5367066 | US5371241 | US5391723 | US5393878 | US5399676 | US5405939 | US5405938 | US5414077 | US5416203 | US5432272 | US5434257 | US5436146 | US5446137 | US5445934 | US5451463 | US5453496 | US5455233 | US5457187 | US5459255 | US5466677 | US5466786 | US5470967 | US5476925 | US5484908 | US5486603 | US5489677 | US5502177 | US5510475 | US5512439 | US5512667 | US5514785 | US5519126 | US5519134 | US5525711 | US5525465 | US5536821 | US5539082 | US5541316 | US5541307 | US5541313 | US5543152 | US5545730 | US5550111 | US5552540 | US5552538 | US5561225 | US5563253 | US5565552 | US5567811 | US5567810 | US5571799 | US5574142 | US5576427 | US5578717 | US5578718 | WO9637194 | US5580731 | US5585481 | WO9640964 | US5587361 | US5587469 | US5587371 | US5591722 | US5591584 | US5594121 | US5596086 | US5596091 | US5595726 | US5597909 | US5597696 | US5599923 | US5599928 | US5602240 | US5608046 | US5607677 | US5610289 | US5610300 | US5614617 | US5618704 | WO9713499 | US5623070 | US5625050 | US5627053 | US5633360 | US5639873 | US5646265 | US5658873 | WO9730731 | US5663312 | US5665557 | US5670633 | US5677437 | US5677439 | US5677195 | US5681941 | US5688941 | US5700920 | US5705188 | US5714331 | US5719262 | US5744305 | US5750692 | US5770722 | WO9839359 | US5854033 | US5874219 | WO9914226 | US5976567 | US5981276 | US5981501 | US6015886 | WO0003683 | US6028188 | WO0022113 | WO0022114 | US6054299 | US6124445 | US6143520 | US6147200 | US6160109 | US6166197 | US6169170 | US6172209 | US6191105 | US6222025 | US6235887 | US6239265 | US6268490 | US6277603 | US6294664 | US6320017 | US6326199 | US6346614 | US6355245 | US6380368 | US6444423 | US2003027780 | US6525191 | US6528640 | US6531590 | US6534639 | US6534484 | US6576752 | US6586410 | US2003144217 | US6608035 | US6617438 | US6639062 | US6670461 | US6683167 | US6747014 | US2004127488 | US6770748 | US2004167116 | US6783931 | US2004171570 | US6794499 | US6815432 | US6858225 | US6858715 | US6867294 | US6878805 | US6887906 | US6900297 | US2005148548 | US2005281781 | US6998484 | US7015315 | US7034133 | US7037646 | US7041816 | US7045610 | US7053207 | US7063860 | US7070802 | US7084125 | US7157099 | USRE39464E | US2007172483 | WO2007091269 | US7273933 | WO2007117686 | US7321029 | US2008039618 | WO2008042973 | US7399845 | US7427672 | US7427605 | US2009012281 | WO2009014887 | US7495088 | US7569686 | WO2009127060 | US7741457 | WO2010141511 | US2010324120 | US7858769 | WO2011005861 | WO2011031520 | US8022193 | US8030467 | US8058069 | US2011313020 | US8101348 | US8106022 | US8158601 | US2012225056 | US8278283 | US8278425 | US8278426 | US8314227 | US2013011922 | WO2013036868 | US2013096289 | US2013190383 | - WALPORT, M.J., N Engl J Med., (20010000), vol. 344, page 1058 | - DUNKELBERGER JR; 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