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Extract from the Register of European Patents

EP About this file: EP3417877

EP3417877 - COMPLEX CAPABLE OF INHIBITING GENETIC FUNCTION IN EXOSOME, AND CANCER PROLIFERATION AND/OR METASTASIS SUPPRESSOR [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  12.08.2021
Database last updated on 12.06.2024
FormerRequest for examination was made
Status updated on  23.11.2018
FormerThe international publication has been made
Status updated on  01.09.2017
Most recent event   Tooltip05.04.2024New entry: Additional fee for renewal fee: despatch of communication + time limit 
Applicant(s)For all designated states
Kyoto University
36-1, Yoshida-honmachi Sakyo-ku
Kyoto-shi, Kyoto 606-8501 / JP
For all designated states
Kyoto Pharmaceutical University
5 Misasagi-Nakauchi-cho
Yamashina-ku
Kyoto-shi, Kyoto 607-8414 / JP
[2018/52]
Inventor(s)01 / YAMAYOSHI, Asako
c/o Kyoto University
36-1 Yoshida-honmachi
Sakyo-ku
Kyoto-shi Kyoto 606-8501 / JP
02 / MURAKAMI, Akira
c/o National University Corporation
Kyoto Institute of Technology
1 Matsugasaki Hashikami-cho
Sakyo-ku
Kyoto-shi Kyoto 606-8585 / JP
03 / ASHIHARA, Eishi
c/o Kyoto Pharmaceutical University
5 Misasagi-Nakauchi-cho
Yamashina-ku
Kyoto-shi Kyoto 607-8414 / JP
04 / KOBORI, Akio
c/o National University Corporation
Kyoto Institute of Technology
1 Matsugasaki Hashikami-cho
Sakyo-ku
Kyoto-shi Kyoto 606-8585 / JP
 [2018/52]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
[2018/52]
Application number, filing date17753337.917.02.2017
[2018/52]
WO2017JP05994
Priority number, dateJP2016002892418.02.2016         Original published format: JP 2016028924
[2018/52]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017142083
Date:24.08.2017
Language:JA
[2017/34]
Type: A1 Application with search report 
No.:EP3417877
Date:26.12.2018
Language:EN
[2018/52]
Search report(s)International search report - published on:JP24.08.2017
(Supplementary) European search report - dispatched on:EP30.08.2019
ClassificationIPC:A61K47/64, A61K47/68, A61K39/395, A61K31/7105, A61K48/00, A61P35/00, A61P35/04, C07K16/28, A61K39/00, C12N15/87, C12N15/11, C12N15/113
[2019/40]
CPC:
A61K31/7105 (EP,CN); A61K47/6849 (EP,CN,US); A61K31/713 (CN);
A61K47/549 (US); A61K47/6455 (EP,US); A61K47/6883 (EP,CN,US);
A61P35/00 (EP,CN,US); A61P35/04 (CN); C07K16/2803 (EP);
C07K16/2896 (EP,US); C12N15/111 (EP); C12N15/113 (EP,US);
C12N15/87 (EP); A61K2039/505 (EP,US); C07K2317/77 (EP,US);
C12N2310/113 (EP,US); C12N2320/31 (EP,US) (-)
C-Set:
A61K31/7105, A61K2300/00 (EP)
Former IPC [2018/52]A61K39/395, A61K31/7105, A61K48/00, A61P35/00, A61P35/04
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/52]
TitleGerman:ZUR HEMMUNG DER GENETISCHEN FUNKTION IN EXOSOM FÄHIGER KOMPLEX UND KREBSPROLIFERATIONS- UND/ODER METASTASESUPPRESSOR[2018/52]
English:COMPLEX CAPABLE OF INHIBITING GENETIC FUNCTION IN EXOSOME, AND CANCER PROLIFERATION AND/OR METASTASIS SUPPRESSOR[2018/52]
French:COMPLEXE CAPABLE D'INHIBER LA FONCTION GÉNÉTIQUE DANS UN EXOSOME, ET SUPPRESSEUR DE LA PROLIFÉRATION ET/OU DE LA MÉTASTASE CANCÉREUSES[2018/52]
Entry into regional phase14.09.2018Translation filed 
14.09.2018National basic fee paid 
14.09.2018Search fee paid 
14.09.2018Designation fee(s) paid 
14.09.2018Examination fee paid 
Examination proceduredeletedDate on which the examining division has become responsible
14.09.2018Examination requested  [2018/52]
17.03.2020Amendment by applicant (claims and/or description)
11.08.2021Despatch of a communication from the examining division (Time limit: M04)
20.12.2021Reply to a communication from the examining division
Fees paidRenewal fee
18.02.2019Renewal fee patent year 03
21.02.2020Renewal fee patent year 04
16.02.2021Renewal fee patent year 05
22.02.2022Renewal fee patent year 06
09.02.2023Renewal fee patent year 07
Penalty fee
Additional fee for renewal fee
29.02.202408   M06   Not yet paid
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Documents cited:Search[XI]WO2012178173  (CT SE LLC [US], et al) [X] 1,2,11,12 * examples 2,3,8 * [I] 1-6,8,11,12;
 [XI]  - SWEENY L ET AL, "A novel extracellular drug conjugate significantly inhibits head and neck squamous cell carcinoma", ORAL ONCOLOGY, (20131001), vol. 49, no. 10, doi:10.1016/j.oraloncology.2013.07.006, ISSN 1368-8375, pages 991 - 997, XP055152770 [X] 1,2,11,12 * abstract * * page 992, section "Reagents" * * figures 1-5 * [I] 1-6,8,11,12

DOI:   http://dx.doi.org/10.1016/j.oraloncology.2013.07.006
 [Y]  - KRICHEVSKY AM ET AL, "miR-21: a small multi-faceted RNA", JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, (20081016), vol. 13, no. 1, doi:10.1111/j.1582-4934.2008.00556.x, ISSN 1582-1838, pages 39 - 53, XP055045933 [Y] 7,9,10 * abstract * * page 49, section "Potential therapeutic target" *

DOI:   http://dx.doi.org/10.1111/j.1582-4934.2008.00556.x
 [YA]  - PEER D ET AL, "Special delivery: targeted therapy with small RNAs", GENE THERAPY, GB, (20110414), vol. 18, no. 12, doi:10.1038/gt.2011.56, ISSN 0969-7128, pages 1127 - 1133, XP055614129 [Y] 7,9,10 * figure 1 * [A] 1-6,8,11,12

DOI:   http://dx.doi.org/10.1038/gt.2011.56
International search[A]WO2013099925  (SHIONOGI & CO [JP]) [A] 1-12 * , paragraph [0001] & US 2015/0010913 A1 paragraph [0001] & EP 2803673 A1 & CA 2860163 A & KR 10-2014-0107615 A & CN 104302667 A *;
 [A]WO2014167969  (SHIONOGI & CO [JP], et al) [A] 1-12 * , paragraph [0001] & US 2016/0047812 A paragraph [0001] & EP 2985605 A1 & CA 2907606 A & CN 105074468 A *;
 [A]  - XIONG B et al., "MiR-21 regulates biological behavior through the PTEN/PI-3 K/Akt signaling pathway in human colorectal cancer cells", International Journal of Oncology, (20130000), vol. 42, no. 1, ISSN 1019-6439, pages 219 - 228, XP055410573 [A] 1-12 * , particularly, page 219, 'Abstract' *

DOI:   http://dx.doi.org/10.3892/ijo.2012.1707
 [A]  - FIORI ME et al., "Antitumor effect of miR-197 targeting in p53 wild-type lung cancer", Cell Death and Differentiation, (20140000), vol. 21, no. 5, ISSN 1350-9047, pages 774 - 782, XP055410574 [A] 1-12 * , particularly, page 774, summary *

DOI:   http://dx.doi.org/10.1038/cdd.2014.6
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