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Extract from the Register of European Patents

EP About this file: EP3507286

EP3507286 - CRYSTALLINE HYDRATE OF THE COMPOUND (2S,3R)-ISOPROPYL 2-(((2-(1,5-DIMETHYL-6-OXO-1,6-DIHYDROPYRIDIN-3-YL)-1-((TETRAHYDRO-2H-PYRAN-4-YL)METHYL)-1H-BENZO[D]IMIDAZOL-5-YL)METHYL)AMINO)-3-HYDROXYBUTANOATE EDISYLATE [Right-click to bookmark this link]
StatusGrant of patent is intended
Status updated on  04.01.2024
Database last updated on 24.08.2024
FormerExamination is in progress
Status updated on  20.11.2023
FormerGrant of patent is intended
Status updated on  30.03.2023
FormerExamination is in progress
Status updated on  16.12.2019
FormerRequest for examination was made
Status updated on  07.06.2019
FormerThe international publication has been made
Status updated on  10.03.2018
Formerunknown
Status updated on  08.09.2017
Most recent event   Tooltip18.06.2024New entry: Application deemed to be withdrawn: despatch of communication + time limit 
Applicant(s)For all designated states
GlaxoSmithKline Intellectual Property Development Limited
980 Great West Road
Brentford
Middlesex TW8 9GS / GB
[2019/28]
Inventor(s)01 / HENLEY, Nicholas Paul
GlaxoSmithKline
Gunnels Wood Road
Stevenage Hertfordshire SG1 2NY / GB
 [2019/28]
Representative(s)Ahern, Jenna Marie
GlaxoSmithKline
Global Patents, CN925.1
980 Great West Road
Brentford, Middlesex TW8 9GS / GB
[N/P]
Former [2019/28]Fowler, Gavin James
GlaxoSmithKline
Global Patents (CN925.1)
980 Great West Road
Brentford, Middlesex TW8 9GS / GB
Application number, filing date17758877.931.08.2017
[2019/28]
WO2017EP71867
Priority number, dateGB2016001493902.09.2016         Original published format: GB 201614939
[2019/28]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018041946
Date:08.03.2018
Language:EN
[2018/10]
Type: A1 Application with search report 
No.:EP3507286
Date:10.07.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 08.03.2018 takes the place of the publication of the European patent application.
[2019/28]
Search report(s)International search report - published on:EP08.03.2018
ClassificationIPC:C07D405/14, A61P19/02, A61K31/4427
[2019/28]
CPC:
C07D405/14 (EP,KR,US); A61K31/4427 (KR); A61P19/02 (EP,KR,US);
C07B2200/13 (KR,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/28]
Extension statesBA28.03.2019
ME28.03.2019
TitleGerman:KRISTALLINES HYDRAT DER VERBINDUNG (2S,3R)-ISOPROPYL-2-(((2-(1,5-DIMETHYL-6-OXO-1,6-DIHYDROPYRIDIN-3-YL)-1-((TETRAHYDRO-2H-PYRAN-4-YL)METHYL)-1H-BENZO[D]IMIDAZOL-5-YL)METHYL)AMINO)-3-HYDROXYBUTANOAT-EDISYLAT[2019/28]
English:CRYSTALLINE HYDRATE OF THE COMPOUND (2S,3R)-ISOPROPYL 2-(((2-(1,5-DIMETHYL-6-OXO-1,6-DIHYDROPYRIDIN-3-YL)-1-((TETRAHYDRO-2H-PYRAN-4-YL)METHYL)-1H-BENZO[D]IMIDAZOL-5-YL)METHYL)AMINO)-3-HYDROXYBUTANOATE EDISYLATE[2019/28]
French:HYDRATE CRISTALLIN DU COMPOSÉ (2S,3R)-ISOPROPYL 2-(((2-(1,5-DIMÉTHYL-6-OXO-1,6-DIHYDROPYRIDIN-3-YL)-1-((TÉTRAHYDRO-2H-PYRAN-4-YL)MÉTHYL)-1H-BENZO[D]IMIDAZOL-5-YL)MÉTHYL)AMINO)-3-HYDROXYBUTANOATE ÉDISYLATE[2019/28]
Entry into regional phase28.03.2019National basic fee paid 
28.03.2019Designation fee(s) paid 
28.03.2019Examination fee paid 
Examination procedure28.03.2019Amendment by applicant (claims and/or description)
28.03.2019Examination requested  [2019/28]
28.03.2019Date on which the examining division has become responsible
19.12.2019Despatch of a communication from the examining division (Time limit: M06)
18.09.2020Reply to a communication from the examining division
08.02.2021Despatch of a communication from the examining division (Time limit: M04)
12.05.2021Reply to a communication from the examining division
29.07.2021Despatch of a communication from the examining division (Time limit: M06)
31.01.2022Reply to a communication from the examining division
31.03.2023Communication of intention to grant the patent
10.08.2023Fee for grant paid
10.08.2023Fee for publishing/printing paid
17.11.2023Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
05.01.2024Communication of intention to grant the patent
17.06.2024Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time
Request for further processing for:The application is deemed to be withdrawn due to failure to fulfill actions required for granting the patent
17.11.2023Request for further processing filed
17.11.2023Full payment received (date of receipt of payment)
Request granted
01.12.2023Decision despatched
The application is deemed to be withdrawn due to failure to reply to the examination report
18.09.2020Request for further processing filed
18.09.2020Full payment received (date of receipt of payment)
Request granted
02.10.2020Decision despatched
Fees paidRenewal fee
08.08.2019Renewal fee patent year 03
17.08.2020Renewal fee patent year 04
18.08.2021Renewal fee patent year 05
19.08.2022Renewal fee patent year 06
22.08.2023Renewal fee patent year 07
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Cited inInternational search[A]US2015051208  (ENGELHARDT HARALD [AT], et al) [A] 1-18* Fromula (Ia1); paragraphs [0001] , [0 61]; claim -; compounds I-25 and I-27, IV-7 *;
 [XDP]WO2016146738  (GLAXOSMITHKLINE IP DEV LTD [GB]) [XDP] 1-18 * pages 23-27; example 303 *
by applicantGB2242134
 WO03061743
 WO2007012871
 WO2007068896
 WO2011054848
 WO2011054846
    - CHUNG et al., J Med. Chem, (20110000), vol. 54, pages 3827 - 3838
    - DAWSON M.A. et al., Nature, (20110000), vol. 478, no. 7370, pages 529 - 33
    - WYCE, A. et al., Oncotarget., (20130000), vol. 4, no. 12, pages 2419 - 29
    - NICODEME E. et al., Nature, (20100000), vol. 468, no. 7327, pages 1119 - 23
    - MELE D.A. et al., Journal of Experimental Medicine, (20130000), vol. 210, no. 11, pages 2181 - 90
    - ANAND P., Cell, (20130000), vol. 154, no. 3, pages 569 - 82
    - TANG X. et al., Molecular Pharmacology, (20130000), vol. 83, no. 1, pages 283 - 293
 WO2016EP55792
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.