-
EP3503722
European procedure
- EP About this file
- EP Legal status
- EP Federated register
- EP Event history
- EP Citations
- EP Patent family
- EP All documents
Extract from the Register of European Patents
EP About this file: EP3503722
| EP3503722 - TRANSGENIC NON-HUMAN ANIMALS PRODUCING MODIFIED HEAVY CHAIN-ONLY ANTIBODIES [Right-click to bookmark this link] | Status | Examination is in progress Status updated on 18.06.2021 Database last updated on 15.06.2024 | |
| Former | Request for examination was made Status updated on 31.05.2019 | ||
| Former | The international publication has been made Status updated on 03.03.2018 | ||
| Former | unknown Status updated on 13.09.2017 | Most recent event Tooltip | 22.08.2023 | New entry: Renewal fee paid | Applicant(s) | For all designated states TeneoBio, Inc. One Amgen Center Drive Thousand Oaks, CA 91320 / US | [2023/33] |
| Former [2020/19] | For all designated states Teneobio, Inc. 7999 Gateway Blvd, Suite 320 Newark, CA 94560 / US | ||
| Former [2019/27] | For all designated states Teneobio, Inc. 1490 O'Brien Drive Suite D Menlo Park, California 94025 / US | Inventor(s) | 01 /
VAN SCHOOTEN, Wim c/o Teneobio, Inc. 1490 O'Brien Drive, Suite D Menlo Park, California 94025 / US | 02 /
TRINKLEIN, Nathan c/o Teneobio, Inc. 1490 O'Brien Drive, Suite D Menlo Park, California 94025 / US | 03 /
FORCE-ALDRED, Shelley c/o Teneobio, Inc. 1490 O'Brien Drive, Suite D Menlo Park, California 94025 / US | 04 /
BRUGGEMANN, Marianne c/o Teneobio, Inc. 1490 O'Brien Drive, Suite D Menlo Park, California 94025 / US | 05 /
OSBORN, Michael c/o Teneobio, Inc. 1490 O'Brien Drive, Suite D Menlo Park, California 94025 / US | [2019/27] | Representative(s) | Mewburn Ellis LLP Aurora Building Counterslip Bristol BS1 6BX / GB | [N/P] |
| Former [2019/27] | Mewburn Ellis LLP City Tower 40 Basinghall Street London EC2V 5DE / GB | Application number, filing date | 17761656.2 | 22.08.2017 | [2019/27] | WO2017US47928 | Priority number, date | US201662379075P | 24.08.2016 Original published format: US 201662379075 P | [2019/27] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2018039180 | Date: | 01.03.2018 | Language: | EN | [2018/09] | Type: | A1 Application with search report | No.: | EP3503722 | Date: | 03.07.2019 | Language: | EN | The application published by WIPO in one of the EPO official languages on 01.03.2018 takes the place of the publication of the European patent application. | [2019/27] | Search report(s) | International search report - published on: | EP | 01.03.2018 | Classification | IPC: | A01K67/027, C07K16/00, C12N15/90 | [2019/27] | CPC: |
C07K16/00 (EP,KR,RU,US);
A01K67/027 (EP,KR,US);
A01K67/0275 (EP,KR,RU,US);
C12N15/902 (EP,KR,RU,US);
A01K2217/052 (EP,KR,US);
A01K2227/105 (KR,US);
A01K2267/01 (EP,US);
C07K2317/21 (EP,KR,US);
C07K2317/24 (US);
C07K2317/35 (US);
C07K2317/52 (US);
C07K2317/522 (EP,KR,US);
C07K2317/565 (US);
C07K2317/567 (EP,KR,US);
C07K2317/569 (EP,KR,US);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2019/27] | Title | German: | MODIFIZIERTE AUSSCHLIESSLICH SCHWERKETTIGE ANTIKÖRPER PRODUZIERENDE TRANSGENE NICHTMENSCHLICHE TIERE | [2019/27] | English: | TRANSGENIC NON-HUMAN ANIMALS PRODUCING MODIFIED HEAVY CHAIN-ONLY ANTIBODIES | [2019/27] | French: | ANIMAUX TRANSGÉNIQUES NON HUMAINS PRODUISANT DES ANTICORPS MODIFIÉS À CHAÎNES LOURDES UNIQUEMENT | [2019/27] | Entry into regional phase | 20.03.2019 | National basic fee paid | 20.03.2019 | Designation fee(s) paid | 20.03.2019 | Examination fee paid | Examination procedure | 20.03.2019 | Examination requested [2019/27] | 20.03.2019 | Date on which the examining division has become responsible | 11.10.2019 | Amendment by applicant (claims and/or description) | 22.06.2021 | Despatch of a communication from the examining division (Time limit: M06) | 24.01.2022 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 01.04.2022 | Reply to a communication from the examining division | 15.09.2022 | Observations by third parties | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the examination report | 01.04.2022 | Request for further processing filed | 01.04.2022 | Full payment received (date of receipt of payment) Request granted | 08.04.2022 | Decision despatched | Fees paid | Renewal fee | 20.03.2019 | Renewal fee patent year 03 | 13.08.2020 | Renewal fee patent year 04 | 13.08.2021 | Renewal fee patent year 05 | 18.07.2022 | Renewal fee patent year 06 | 22.08.2023 | Renewal fee patent year 07 |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [XY]WO03035694 (VLAAMS INTERUNIV INST BIOTECH [BE], et al) [X] 1-15,18-24 * page 2 - page 3; examples 1,5 * [Y] 16,17,25-61; | [XY]WO2008074839 (ABLYNX NV [BE], et al) [X] 1-15,18-24 * abstract * [Y] 16,17,25-61; | [Y]WO2010109165 (UNIV ERASMUS MEDICAL CT [NL], et al) [Y] 16,17,25-61 * the whole document *; | [XY] - DESMYTER ALINE ET AL, "Antigen specificity and high affinity binding provided by one single loop of a camel single-domain antibody", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, (20010713), vol. 276, no. 28, doi:10.1074/JBC.M102107200, ISSN 0021-9258, pages 26285 - 26290, XP002190005 [X] 1-7,9-13,15,18-24 * abstract * [Y] 16,17,25-61 DOI: http://dx.doi.org/10.1074/jbc.M102107200 | [Y] - JANSSENS RICK ET AL, "Generation of heavy-chain-only antibodies in mice", PROCEEDINGS NATIONAL ACADEMY OF SCIENCES PNAS, NATIONAL ACADEMY OF SCIENCES, US, (20061010), vol. 103, no. 41, doi:10.1073/PNAS.0601108103, ISSN 0027-8424, pages 15130 - 15135, XP002494537 [Y] 16,17,25-61 * the whole document * DOI: http://dx.doi.org/10.1073/pnas.0601108103 | [A] - Benny K. C. Lo ET AL, "The Kabat Database and a Bioinformatics Example", Antibody Engineering, New Jersey, Humana Press, (20031205), vol. 248, pages 11 - 26, doi:10.1385/1-59259-666-5:11, ISBN 978-1-59259-666-9, XP055418398 [A] 1-61 * table 1 * DOI: http://dx.doi.org/10.1385/1-59259-666-5:11 | [L] - E A Kabat ET AL, "Sequences and proteins of immunological interest , Fifth Edition", Bethesda, MD : U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, 1991., vol. 1, (19910101), page 310, URL: https://books.google.co.uk/books?id=3jMvZYW2ZtwC&lpg=PA1137-IA1&pg=PP1#v=onepage&q&f=false, (20171024), XP055418434 [L] 1-61 * Sequences numbering according of KABAT position 1 of FR4 of Heavy chain; page 310 * | by applicant | WO2004062551 | WO2006008548 | US7541513 | US2010122358 | US8367888 | US8410249 | US8883150 | - Basic and Clinical Immunology, Appleton & Lange, (19940000), page 71 | - MUYLDERMANS, JBiotechnol, (20010000), vol. 74, pages 277 - 302 | - REVETS et al., Expert Opin Biol Ther, (20050000), vol. 5, pages 111 - 124 | - JATON et al., Biochemistry, (19680000), vol. 7, pages 4185 - 4195 | - SITIA et al., Cell, (19900000), vol. 60, pages 781 - 790 | - BARTHELEMY et al., J. Biol. Chem., (20080000), vol. 283, pages 3639 - 3654 | - NGUYEN et al., Immunology, (20030000), vol. 109, no. 1, pages 93 - 101 | - BRIIGGEMANN et al., Crit. Rev. Immunol., (20060000), vol. 26, no. 5, pages 377 - 90 | - ZOU et al., J Exp A4ed, (20070000), vol. 204, no. 13, pages 3271 - 3283 | - GEURTS et al., Science, (20090000), vol. 325, no. 5939, page 433 | - MENORET et al., European Journal of Immunology, (20100000), vol. 40, pages 2932 - 2941 | - IRI-SOFLA et al., Experimental Cell Research, (20110000), vol. 317, pages 2630 - 2641 | - JAMNANI et al., Biochim Biophys Acta, (20140000), vol. 1840, pages 378 - 386 | - Methods in Enzymology, Academic Press, Inc. | - KABAT et al., NIH Publ., (19910000), vol. 1, no. 91-3242, pages 647 - 669 | - HOLT et al., Domain antibodies:proteins for therapy'' Trends in Biotechnology, (20030000), vol. 21, no. 11, pages 484 - 490 | - J Nat! Cancer Inst, (20150000), vol. 108, no. 7, page dvj439 | - JACKSON et al., Nature Reviews Clinical Oncology, (20160000), vol. 13, pages 370 - 383 | - CHEN et al., J. Mol. Biol., (19990000), vol. 293, pages 865 - 881 | - GEURTS et al., Science, (20090000), vol. 325, page 433 | - MENORET et al., Eur. J. Immunol., (20100000), vol. 40, pages 2932 - 2941 | - CUI et al., Nat Biotechnol, (20110000), vol. 29, pages 64 - 67 | - OSBORN et al., J. Immunol., (20130000), vol. 190, pages 1481 - 1490 | - MA et al., J. Immunol. Methods, (20130000), vol. 400-401, pages 78 - 86 | - MARCHUK; COLLINS, Nucleic Acids Res., (19880000), vol. 16, no. 15, page 7743 | - MA et al., Mol Microbiol., (20070000), vol. 66, no. 1, pages 14 - 25 | - GU et al., J. Biochem. Biophys Methods., (19920000), vol. 24, pages 45 - 50 | - "Human antibody repertoires in transgenic mice: manipulation of transfer of YACs", DAVIES et al., In Antibody Engineering: A Practical Approach, IRL, (19960000), pages 59 - 76 | - YANG et al., Nat. Biotechnol. 1997, (19970000), vol. 15, pages 859 - 865 | - BOGARD et al., Infection and Immunity, (19870000), vol. 55, no. 4, pages 899 - 908 | - DE KIEVIT; LAM, Journal of Bacteriology, (19941200), pages 7129 - 7139 | - A. BRUCKNER GUIQING WANG; JANET F. HINDLER; KEVIN W. WARD; DAVID, J. Clin. Microbiol., (20060000), vol. 44, no. 11, page 3883 | - TRANSY et al., Eur J Immunol, (19890000), vol. 19, no. 5, pages 947 - 50 | - BRIIGGEMANN et al., JI, (19890000), vol. 142, page 3145 | - REDDY et al., Nature Biotechnology, (20100000), vol. 28, pages 965 - 969 | - OUISSE et al., BMC Biotechnology, (20170000), vol. 17, no. 3, pages 1 - 17 | - KOHLER; MILSTEIN, Nature, (19750000), vol. 256, no. 495 | - KAY et al., Nature Biotechnology, (20100000), vol. 28, no. 12, pages 1287 - 1289 | - GAO, Nucleic Acids Research, (20030000), vol. 3 1, no. 22, page e143 | - ANDREASON; EVANS, Anal. Biochem., (19890000), vol. 180, no. 2, pages 269 - 75 | - BAKER; COTTEN, Nucleic Acid Res., (19970000), vol. 25, no. 10, pages 1950 - 6 | other | WO2006008548 | - P. A. Barthelemy, H. Raab, B. A. Appleton, C. J. Bond, P. Wu, C. Wiesmann, S. S. Sidhu, "Comprehensive Analysis of the Factors Contributing to the Stability and Solubility of Autonomous Human VH Domains", Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, (20080201), vol. 283, no. 6, doi:10.1074/jbc.M708536200, ISSN 00219258, pages 3639 - 3654, XP055040419 DOI: http://dx.doi.org/10.1074/jbc.M708536200 | - Clarke Starlynn C; Ma Biao; Trinklein Nathan D; Schellenberger Ute; Osborn Michael J; Ouisse Laure-Hélène; Boudreau Andrew; Davison Laura M; Harris Katherine E; Ugamraj Harshad S; Balasubramani Aarti; Dang Kevin H; Jorgensen Brett; Ogana Heather Anne N; Pham Duy T; Pratap Payal P; Sankaran Preethi; Anegon Ignacio; van Schooten Wim C; Brueggemann Marianne; Buelow Roland; Force Aldred Shelley, "Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies.", Frontiers in Immunology, Frontiers Media, Lausanne, CH, Lausanne, CH , (20180101), vol. 9, doi:10.3389/fimmu.2018.03037, ISSN 1664-3224, page 3037, XP009512208 DOI: http://dx.doi.org/10.3389/fimmu.2018.03037 |