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Extract from the Register of European Patents

EP About this file: EP3538654

EP3538654 - OLIGONUCLEOTIDE TARGETING STRATEGY FOR HBV CCCDNA [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  29.09.2023
Database last updated on 19.07.2024
FormerExamination is in progress
Status updated on  05.02.2021
FormerRequest for examination was made
Status updated on  16.08.2019
FormerThe international publication has been made
Status updated on  18.05.2018
Formerunknown
Status updated on  05.12.2017
Most recent event   Tooltip29.09.2023Application deemed to be withdrawnpublished on 01.11.2023  [2023/44]
Applicant(s)For all designated states
Janssen BioPharma, Inc.
260 E. Grand Avenue, 2nd Floor
South San Francisco, CA 94080 / US
[2019/38]
Inventor(s)01 / GRYAZNOV, Sergei
260 East Grand Avenue
2nd Floor
South San Francisco California 94080 / US
02 / FITZGERALD, Megan
260 E. Grand Ave.
2nd Floor
South San Francisco California 94080 / US
03 / STOYCHEVA, Antitsa Dimitrova
114 Carnoustie Drive
Half Moon Bay, CA 94019 / US
04 / HONG, Jin
6 Spruce Ct.
Pacifica, CA 94044 / US
 [2020/13]
Former [2019/38]01 / GRYAZNOV, Sergeiq
260 East Grand Avenue
2nd Floor
South San Francisco California 94080 / US
02 / FITZGERALD, Megan
260 E. Grand Ave.
2nd Floor
South San Francisco California 94080 / US
03 / STOYCHEVA, Antitsa Dimitrova
114 Carnoustie Drive
Half Moon Bay, CA 94019 / US
04 / HONG, Jin
6 Spruce Ct.
Pacifica, CA 94044 / US
Representative(s)Kilburn & Strode LLP
Lacon London
84 Theobalds Road
Holborn
London WC1X 8NL / GB
[N/P]
Former [2019/38]Cornish, Kristina Victoria Joy, et al
Kilburn & Strode LLP
Lacon London
84 Theobalds Road
London WC1X 8NL / GB
Application number, filing date17804414.513.11.2017
[2019/38]
WO2017US61348
Priority number, dateUS201662420801P11.11.2016         Original published format: US 201662420801 P
US201762558770P14.09.2017         Original published format: US 201762558770 P
[2019/38]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018089914
Date:17.05.2018
Language:EN
[2018/20]
Type: A1 Application with search report 
No.:EP3538654
Date:18.09.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 17.05.2018 takes the place of the publication of the European patent application.
[2019/38]
Search report(s)International search report - published on:EP17.05.2018
ClassificationIPC:C12N15/113
[2019/38]
CPC:
C12N15/1131 (EP,US); C12N15/113 (KR); A61K31/7125 (EP,KR,US);
A61K45/06 (KR,US); A61P31/20 (EP,KR,US); C12N2310/11 (EP,KR,US);
C12N2310/314 (KR,US); C12N2310/315 (KR,US); C12N2310/321 (KR,US);
C12N2310/3341 (KR,US); C12N2310/34 (KR,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/38]
Extension statesBA21.05.2019
ME21.05.2019
TitleGerman:OLIGONUKLEOTID-TARGETING-STRATEGIE FÜR HBV-CCCDNA[2019/38]
English:OLIGONUCLEOTIDE TARGETING STRATEGY FOR HBV CCCDNA[2019/38]
French:STRATÉGIE DE CIBLAGE D'OLIGONUCLÉOTIDE POUR L'ADNCCC DU VHB[2019/38]
Entry into regional phase21.05.2019National basic fee paid 
21.05.2019Designation fee(s) paid 
21.05.2019Examination fee paid 
Examination procedure21.05.2019Examination requested  [2019/38]
21.05.2019Date on which the examining division has become responsible
18.12.2019Amendment by applicant (claims and/or description)
04.02.2021Despatch of a communication from the examining division (Time limit: M06)
12.08.2021Reply to a communication from the examining division
01.06.2023Application deemed to be withdrawn, date of legal effect  [2023/44]
22.06.2023Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2023/44]
Fees paidRenewal fee
14.11.2019Renewal fee patent year 03
13.11.2020Renewal fee patent year 04
21.10.2021Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
30.11.202206   M06   Not yet paid
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Cited inInternational search[XI]WO2012145697  (ISIS PHARMACEUTICALS INC [US], et al) [X] 1-3,5,14,15,17,19,20 * page 111, line 9 - line 23 * * page 117 - page 118 * * page 156 * * claim - * * the whole document * [I] 4,8,11,12,16;
 [A]  - S.M. GRYAZNOV, "Oligonucleotide n3'-->p5' phosphoramidates and thio-phoshoramidates as potential therapeutic agents", Chemistry & biodiversity, Switzerland, (20100301), page 477, URL: http://onlinelibrary.wiley.com/store/10.1002/cbdv.200900187/asset/477_ftp.pdf?v=1&t=jcw5hrtu&s=1e98f50cf2b74417c6a924c09c65ac0f288965cc, (20180126), XP055445374 [A] 8 * the whole document *
 [A]  - BILLIOUD GAETAN ET AL., "In vivo reduction of hepatitis B virus antigenemia and viremia by antisense oligonucleotides", JOURNAL OF HEPATOLOGY, (20160401), vol. 64, no. 4, doi:10.1016/J.JHEP.2015.11.032, ISSN 0168-8278, pages 781 - 789, XP029448832 [A] 1-20 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.jhep.2015.11.032
 [A]  - GAETAN BILLIOUD ET AL., "Supplementary information - In vivo reduction of hepatitis B virus antigenemia and viremia by antisense oligonucleotides", JOURNAL OF HEPATOLOGY, AMSTERDAM, NL, (20160401), vol. 64, no. 4, doi:10.1016/j.jhep.2015.11.032, ISSN 0168-8278, pages 781 - 789, XP055445356 [A] 1-20 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.jhep.2015.11.032
 [A]  - MOHUBE MAEPA ET AL., "Progress and prospects of anti-HBV gene therapy development", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, (20150731), vol. 16, no. 8, doi:10.3390/ijms160817589, pages 17589 - 17610, XP055444220 [A] 1-20 * the whole document *

DOI:   http://dx.doi.org/10.3390/ijms160817589
 [A]  - KAZUTO TAJIRI ET AL., "New horizon for radical cure of chronic hepatitis B virus infection", WORLD JOURNAL OF HEPATOLOGY, (20160101), vol. 8, no. 21, doi:10.4254/wjh.v8.i21.863, ISSN 1948-5182, page 863, XP055444225 [A] 1-20 * the whole document *

DOI:   http://dx.doi.org/10.4254/wjh.v8.i21.863
by applicantUS6747014
    - KASAMATSU, H.; ROBBERSON, D. L.; VINOGRAD, J., Proc Natl Acad Sci., (19710000), vol. 68, no. 9, pages 2252 - 2257
    - SEBESTA, M. et al., DNA Repair, (20130000), vol. 12, no. 9, pages 691 - 698
    - "Amplification of Genomic DNA", SAIKI et al., PCR PROTOCOLS, Academic Press, (19900000), pages 13 - 20
    - WHARAM et al., Nucleic Acids Res., (20010601), vol. 29, no. 11, pages E54 - E54
    - HAFNER et al., Biotechniques, (20010400), vol. 30, no. 4, pages 852 - 6,858,860
    - ZIELINSKA, D.; PONGRACZ, K; GRYAZNOV, S. M., Tetrahedron Lett., (20060000), vol. 47, pages 4495 - 4499
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.