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Extract from the Register of European Patents

EP About this file: EP3551332

EP3551332 - INTEGRATED PURIFICATION AND MEASUREMENT OF DNA METHYLATION AND CO-MEASUREMENT OF MUTATIONS AND/OR MRNA EXPRESSION LEVELS IN AN AUTOMATED REACTION CARTRIDGE [Right-click to bookmark this link]
StatusThe patent has been granted
Status updated on  08.12.2023
Database last updated on 03.10.2024
FormerGrant of patent is intended
Status updated on  26.07.2023
FormerExamination is in progress
Status updated on  06.11.2020
FormerRequest for examination was made
Status updated on  13.09.2019
FormerThe international publication has been made
Status updated on  23.06.2018
Formerunknown
Status updated on  12.01.2018
Most recent event   Tooltip02.08.2024Lapse of the patent in a contracting state
New state(s): LV, PL, PT		published on 04.09.2024  [2024/36]
Applicant(s)For all designated states
Cepheid
904 Caribbean Drive
Sunnyvale, CA 94089 / US
[2019/42]
Inventor(s)01 / LAI, Edwin Wei-Lung
904 Caribbean Drive
Sunnyvale, California 94089 / US
02 / KOHLWAY, Andrew
904 Caribbean Drive
Sunnyvale, California 94089 / US
03 / VAN ATTA, Reuel
904 Caribbean Drive
Sunnyvale, California 94089 / US
04 / HIGUCHI, Russell
904 Caribbean Drive
Sunnyvale, California 94089 / US
05 / GALL, Alexander A.
904 Caribbean Drive
Sunnyvale, California 94089 / US
06 / KOCMOND, Kriszten
904 Caribbean Drive
Sunnyvale, California 94089 / US
 [2019/42]
Representative(s)Patent Boutique LLP
10A Printing House Yard
Hackney Road
London E2 7PR / GB
[2024/02]
Former [2019/42]Patent Boutique LLP
10A Printing House Yard
Hackney Road
London E2 7PR / GB
Application number, filing date17822953.012.12.2017
[2019/42]
WO2017US65905
Priority number, dateUS201662433165P12.12.2016         Original published format: US 201662433165 P
[2019/42]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018111935
Date:21.06.2018
Language:EN
[2018/25]
Type: A1 Application with search report 
No.:EP3551332
Date:16.10.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 21.06.2018 takes the place of the publication of the European patent application.
[2019/42]
Type: B1 Patent specification 
No.:EP3551332
Date:10.01.2024
Language:EN
[2024/02]
Search report(s)International search report - published on:EP21.06.2018
ClassificationIPC:B01L7/00, C12Q1/6827, C12N15/10, G01N35/00
[2019/42]
CPC:
B01L3/502 (EP,KR,US); G01N35/00 (KR); B01L7/52 (EP,KR,US);
C12N15/1006 (KR,US); C12Q1/6827 (EP,KR,US); C12Q1/6853 (KR,US);
C12Q1/686 (KR,US); B01L2200/0652 (KR); B01L2200/0663 (KR);
B01L2200/16 (EP,US); B01L2300/0816 (US); B01L2300/0861 (KR,US);
B01L2300/0864 (EP,KR,US); B01L2300/087 (EP,KR,US); B01L2300/1805 (EP,KR,US);
B01L2400/0478 (EP,KR,US); B01L2400/0644 (EP,KR,US); B01L3/5027 (EP,US);
C12Q2523/125 (KR); C12Q2531/113 (KR); C12Q2535/122 (KR);
C12Q2537/143 (KR,US); C12Q2537/149 (KR,US); C12Q2537/164 (KR,US) (-)
C-Set:
C12Q1/6827, C12Q2523/125, C12Q2531/113, C12Q2535/122 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/42]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TNNot yet paid
TitleGerman:INTEGRIERTE REINIGUNG UND MESSUNG DER DNA-METHYLIERUNG UND KO-MESSUNG VON MUTATIONEN UND/ODER MRNA-EXPRESSIONSNIVEAUS IN EINER AUTOMATISIERTEN REAKTIONSKARTUSCHE[2019/42]
English:INTEGRATED PURIFICATION AND MEASUREMENT OF DNA METHYLATION AND CO-MEASUREMENT OF MUTATIONS AND/OR MRNA EXPRESSION LEVELS IN AN AUTOMATED REACTION CARTRIDGE[2019/42]
French:PURIFICATION ET MESURE DE LA MÉTHYLATION DE L'ADN INTÉGRÉES ET CO-MESURE DES MUTATIONS ET/OU DES NIVEAUX D'EXPRESSION DE L'ARNM DANS UNE CARTOUCHE DE RÉACTION AUTOMATISÉE[2019/42]
Entry into regional phase09.07.2019National basic fee paid 
09.07.2019Designation fee(s) paid 
09.07.2019Examination fee paid 
Examination procedure09.07.2019Examination requested  [2019/42]
09.07.2019Date on which the examining division has become responsible
07.02.2020Amendment by applicant (claims and/or description)
05.11.2020Despatch of a communication from the examining division (Time limit: M06)
14.05.2021Reply to a communication from the examining division
23.03.2022Despatch of a communication from the examining division (Time limit: M06)
13.09.2022Reply to a communication from the examining division
27.07.2023Communication of intention to grant the patent
06.12.2023Fee for grant paid
06.12.2023Fee for publishing/printing paid
06.12.2023Receipt of the translation of the claim(s)
Fees paidRenewal fee
27.02.2020Renewal fee patent year 03
14.12.2020Renewal fee patent year 04
30.11.2021Renewal fee patent year 05
13.10.2022Renewal fee patent year 06
15.11.2023Renewal fee patent year 07
Penalty fee
Additional fee for renewal fee
31.12.201903   M06   Fee paid on   27.02.2020
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT10.01.2024
BG10.01.2024
ES10.01.2024
HR10.01.2024
LT10.01.2024
LV10.01.2024
NL10.01.2024
PL10.01.2024
NO10.04.2024
RS10.04.2024
GR11.04.2024
IS10.05.2024
PT10.05.2024
[2024/36]
Former [2024/35]AT10.01.2024
BG10.01.2024
ES10.01.2024
HR10.01.2024
LT10.01.2024
NL10.01.2024
NO10.04.2024
RS10.04.2024
GR11.04.2024
IS10.05.2024
Former [2024/34]BG10.01.2024
HR10.01.2024
LT10.01.2024
NL10.01.2024
NO10.04.2024
RS10.04.2024
GR11.04.2024
IS10.05.2024
Former [2024/33]LT10.01.2024
NL10.01.2024
NO10.04.2024
IS10.05.2024
Former [2024/32]NL10.01.2024
IS10.05.2024
Former [2024/31]NL10.01.2024
Cited inInternational search[Y]US2015119268  (BISHOP JOHN L [US]) [Y] 1-31 * paragraphs [0047] , [0055] , [0081] - [0083] * * figures 1-3 * * abstract * * the whole document *;
 [XP]WO2016205233  (CEPHEID [US]) [XP] 1-31 * figures 1-39 * * claims 1-128 * * abstract ** the whole document *;
 [Y]  - Ben Butkus, "Hopkins Lab, Cepheid Developing Methylated DNA Panel for Breast Cancer Dx, Monitoring | GenomeWeb", (20151106), URL: https://www.genomeweb.com/molecular-diagnostics/hopkins-lab-cepheid-developing-methylated-dna-panel-breast-cancer-dx#.Wq97n2fderg, (20180319), XP055460431 [Y] 1-31 * page 2, paragraphs 1-3 * * abstract * * the whole document *
Examination   - Emily Eva Holmes ET AL, "Performance Evaluation of Kits for Bisulfite-Conversion of DNA from Tissues, Cell Lines, FFPE Tissues, Aspirates, Lavages, Effusions, Plasma, Serum, and Urine", PLoS ONE, (20140403), vol. 9, no. 4, doi:10.1371/journal.pone.0093933, page e93933, XP055224494

DOI:   http://dx.doi.org/10.1371/journal.pone.0093933
by applicantEP0070685
 US5210015
 US5538848
 WO9731256
 US5686243
 WO9803673
 US5830711
 US5958349
 US6027998
 US6027889
 WO0056927
 US6150097
 WO0192579
 US6403037
 US6440725
 US6605451
 US6783736
 US6818185
 US2006068399
 WO2014052551
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.