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Extract from the Register of European Patents

EP About this file: EP3559218

EP3559218 - GLUCOSE DEHYDROGENASE VARIANTS WITH IMPROVED PROPERTIES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  29.04.2022
Database last updated on 15.06.2024
FormerGrant of patent is intended
Status updated on  15.07.2021
FormerExamination is in progress
Status updated on  11.09.2020
FormerRequest for examination was made
Status updated on  27.09.2019
FormerThe international publication has been made
Status updated on  30.06.2018
Formerunknown
Status updated on  29.01.2018
Most recent event   Tooltip29.04.2022Application deemed to be withdrawnpublished on 01.06.2022  [2022/22]
Applicant(s)For:DE 
Roche Diabetes Care GmbH
Sandhofer Straße 116
68305 Mannheim / DE
For:AL  AT  BE  BG  CH  CY  CZ  DK  EE  ES  FI  FR  GB  GR  HR  HU  IE  IS  IT  LI  LT  LU  LV  MC  MK  MT  NL  NO  PL  PT  RO  RS  SE  SI  SK  SM  TR 
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
[2019/44]
Inventor(s)01 / BOENITZ-DULAT, Mara
c/o Roche Diagnostics GmbH
Nonnenwald 2
82377 Penzberg / DE
02 / HORN, Carina
c/o Roche Diagnostics GmbH
Sandhofer Strasse 116
68305 Mannheim / DE
03 / KRATZSCH, Peter
c/o Roche Diagnostics GmbH
Nonnenwald 2
82377 Penzberg / DE
04 / MEIER, Thomas
c/o Roche Diagnostics GmbH
Nonnenwald 2
82377 Penzberg / DE
05 / RUDOLPH, Markus
c/o F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
06 / SCHNEIDINGER, Bernd
c/o Roche Diabetes Care GmbH
Sandhofer Strasse 116
68305 Mannheim / DE
 [2019/44]
Representative(s)Meinel, Anne Julia, et al
Roche Diabetes Care GmbH
Sandhofer Straße 116
68305 Mannheim / DE
[2019/44]
Application number, filing date17832074.322.12.2017
[2019/44]
WO2017EP84347
Priority number, dateEP2016020647922.12.2016         Original published format: EP 16206479
[2019/44]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018115422
Date:28.06.2018
Language:EN
[2018/26]
Type: A1 Application with search report 
No.:EP3559218
Date:30.10.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 28.06.2018 takes the place of the publication of the European patent application.
[2019/44]
Search report(s)International search report - published on:EP28.06.2018
ClassificationIPC:C12N9/04, C12N15/52
[2019/44]
CPC:
C12N9/0006 (EP,US); C12N15/52 (EP); C12Q1/32 (US);
C12Y101/01047 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/44]
TitleGerman:GLUCOSEDEHYDROGENASEVARIANTEN MIT VERBESSERTEN EIGENSCHAFTEN[2019/44]
English:GLUCOSE DEHYDROGENASE VARIANTS WITH IMPROVED PROPERTIES[2019/44]
French:VARIANTES DE GLUCOSE DÉSHYDROGÉNASE À PROPRIÉTÉS AMÉLIORÉES[2020/35]
Former [2019/44]VARIANTS DE GLUCOSE DÉSHYDROGÉNASE PRÉSENTANT DES PROPRIÉTÉS AMÉLIORÉES
Entry into regional phase22.07.2019National basic fee paid 
22.07.2019Designation fee(s) paid 
22.07.2019Examination fee paid 
Examination procedure22.07.2019Examination requested  [2019/44]
22.07.2019Date on which the examining division has become responsible
11.02.2020Amendment by applicant (claims and/or description)
15.09.2020Despatch of a communication from the examining division (Time limit: M06)
25.03.2021Reply to a communication from the examining division
16.07.2021Communication of intention to grant the patent
27.11.2021Application deemed to be withdrawn, date of legal effect  [2022/22]
12.01.2022Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2022/22]
Fees paidRenewal fee
10.12.2019Renewal fee patent year 03
09.12.2020Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
31.12.202105   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[A]WO2005045016  (CODEXIS INC [US]) [A] 1,5-15 * page 29, paragraph 89 * * table 1 ** page 32 - page 33; table 2 *;
 [A]WO2011020856  (HOFFMANN LA ROCHE [CH], et al) [A] 1,5-15 * page 7, line 3 - line 12 * * page 19, line 20 - line 24; figure 8 *;
 [A]  - BO LIANG ET AL, "Simultaneously improving stability and specificity of cell surface displayed glucose dehydrogenase mutants to construct whole-cell biocatalyst for glucose biosensor application", BIORESOURCE TECHNOLOGY., GB, (20131101), vol. 147, doi:10.1016/j.biortech.2013.08.088, ISSN 0960-8524, pages 492 - 498, XP055344979 [A] 1,5-15 * abstract * * page 495; figure 2 * * page 496, column r, paragraph l; figure 3 *

DOI:   http://dx.doi.org/10.1016/j.biortech.2013.08.088
 [A]  - BAIK SANG-HO ET AL, "Cooperative effect of two surface amino acid mutations (Q252L and E170K) in glucose dehydrogenase from Bacillus megaterium IWG3 on stabilization of its oligomeric state", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, (20050601), vol. 71, no. 6, doi:10.1128/AEM.71.6.3285-3293.2005, ISSN 0099-2240, pages 3285 - 3293, XP002580338 [A] 1,5-15 * abstract * * page 3286; table 1 *

DOI:   http://dx.doi.org/10.1128/AEM.71.6.3285-3293.2005
 [A]  - S.-H. BAIK ET AL, "Significantly enhanced stability of glucose dehydrogenase by directed evolution", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, DE, (20030305), vol. 61, no. 4, doi:10.1007/s00253-002-1215-1, ISSN 0175-7598, pages 329 - 335, XP055344908 [A] 1,5-15 * abstract * * page 332, column r, paragraph l - page 334, column l, paragraph f; figures 1,2 *

DOI:   http://dx.doi.org/10.1007/s00253-002-1215-1
by applicantEP0262445
 EP0302287
 US4816224
 EP0354441
 EP0431456
 US5413690
 US5762770
 US5997817
 US6541216
 US2005214891
 EP1593434
 WO2007001249
 WO2007012494
 WO2009103540
 WO2011012270
 WO2014195363
    - N. J. OPPENHEIMER, The Pyridine Nucleotide Coenzymes, Academic Press, (19820000), pages 56 - 65
    - HILT et al., Biochim Biophys Acta, (19910129), vol. 1076, no. 2, pages 298 - 304
    - S.-H. BAIK et al., Appl. Microbial Biotechnol., (20030000), vol. 61, pages 329 - 335
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.