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Extract from the Register of European Patents

EP About this file: EP3559036

EP3559036 - ANTI-HUMAN CXCR3 ANTIBODIES FOR TREATMENT OF VITILIGO [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  11.05.2021
Database last updated on 14.09.2024
FormerExamination is in progress
Status updated on  07.08.2020
FormerRequest for examination was made
Status updated on  27.09.2019
FormerThe international publication has been made
Status updated on  30.06.2018
Formerunknown
Status updated on  29.01.2018
Most recent event   Tooltip11.05.2021Application deemed to be withdrawnpublished on 09.06.2021  [2021/23]
Applicant(s)For all designated states
Sanofi
54, rue La Boétie
75008 Paris / FR
For all designated states
The University of Massachusetts
One Beacon Street
31st Floor
Boston, MA 02108 / US
[2019/44]
Inventor(s)01 / BRONDYK, William, H.
c/o Sanofi
55 Corporate Drive
Mail Code: 55A-505A
Bridgewater, NJ 08807 / US
02 / CHU, Ruiyin
c/o Sanofi
55 Corporate Drive
Mail Code: 55A-505A
Bridgewater, NJ 08807 / US
03 / CONNORS, Timothy, D.
c/o Sanofi
55 Corporate Drive
Mail Code: 55A-505A
Bridgewater, NJ 08807 / US
04 / PARK, Sunghae
c/o Sanofi
55 Corporate Drive
Mail Code: 55A-505A
Bridgewater, NJ 08807 / US
05 / QIU, Huawei
c/o Sanofi
55 Corporate Drive
Mail Code: 55A-505A
Bridgewater, NJ 08807 / US
06 / YOUD, Michele
c/o Sanofi
55 Corporate Drive
Mail Code: 55A-505A
Bridgewater, NJ 08807 / US
07 / HARRIS, John
c/o University of Massachusetts
One Beacon Street 31st Floor
Boston, MA 02108 / US
08 / RICHMOND, Jillian
c/o University Of Massachusetts
One Beacon Street 31st Floor
Boston, MA 02108 / US
 [2019/44]
Representative(s)Zwicker, Jörk
ZSP Patentanwälte PartG mbB
Hansastraße 32
80686 München / DE
[2019/44]
Application number, filing date17832143.621.12.2017
[2019/44]
WO2017US67988
Priority number, dateUS201662437889P22.12.2016         Original published format: US 201662437889 P
EP2017030677014.12.2017         Original published format: EP 17306770
[2019/44]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018119288
Date:28.06.2018
Language:EN
[2018/26]
Type: A1 Application with search report 
No.:EP3559036
Date:30.10.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 28.06.2018 takes the place of the publication of the European patent application.
[2019/44]
Search report(s)International search report - published on:EP28.06.2018
ClassificationIPC:C07K16/28, A61P17/00, A61P37/00
[2019/44]
CPC:
C07K16/2866 (EP,KR); A61P17/00 (EP,KR); A61P37/00 (EP,KR);
A61K2039/505 (EP,KR); C07K2317/14 (KR); C07K2317/24 (EP,KR);
C07K2317/41 (EP,KR); C07K2317/52 (KR); C07K2317/56 (KR);
C07K2317/565 (KR); C07K2317/72 (EP,KR); C07K2317/732 (EP,KR);
C07K2317/734 (EP,KR); C07K2317/92 (KR); C07K2317/94 (KR) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/44]
TitleGerman:ANTI-HUMAN-CXCR3-ANTIKÖRPER ZUR BEHANDLUNG VON VITILIGO[2019/44]
English:ANTI-HUMAN CXCR3 ANTIBODIES FOR TREATMENT OF VITILIGO[2019/44]
French:ANTICORPS ANTI-CXCR3 HUMAINS POUR LE TRAITEMENT DU VITILIGO[2019/44]
Entry into regional phase28.06.2019National basic fee paid 
28.06.2019Designation fee(s) paid 
28.06.2019Examination fee paid 
Examination procedure28.06.2019Examination requested  [2019/44]
28.06.2019Date on which the examining division has become responsible
27.01.2020Amendment by applicant (claims and/or description)
11.08.2020Despatch of a communication from the examining division (Time limit: M04)
22.12.2020Application deemed to be withdrawn, date of legal effect  [2021/23]
01.02.2021Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2021/23]
Fees paidRenewal fee
13.12.2019Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
31.12.202004   M06   Not yet paid
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Cited inInternational search[A]WO2007048122  (GENZYME CORP [US], et al) [A] 13-15,28-30 * the whole document * * in particular pages 6 and 16 *;
 [A]WO2008094942  (COGENESYS INC [US], et al) [A] 1-32 * the whole document * * in particular pages 2-9 *;
 [A]WO2013109974  (GENZYME CORP [US]) [A] 1-32 * the whole document * * in particular, examples 8 and 13 and figure 22 *;
 [A]WO2014186842  (UNIV MONASH [AU]) [A] 1-32 * in particular, pages 21-29, §20 on page 8 and §86 on page 28 *;
 [A]US2016053013  (SWANSON BARBARA A [US], et al) [A] 1-32 * the whole document * * in particular, pages 1-10 *;
 [I]  - Mauro Picardo ET AL, "Vitiligo International Symposium Rome 2-3 December 2016", doi:10.1034/j.1600-0781.2003.00321.x, (20161203), URL: http://www.vis2016.org/pdf/Programma_VIS.pdf, (20180302), XP055456015 [I] 1-32 * page 3 *

DOI:   http://dx.doi.org/10.1034/j.1600-0781.2003.00321.x
    [ ] - ANONYMOUS, "Vitiligo International Symposium 2016", PIGMENT CELL & MELANOMA RESEARCH, (20170207), vol. 30, no. 5, page e1, XP055456011
 [A]  - John Harris, "Targeting IFN gamma and chemokines to treat vitiligo in a humanized mouse model", (2015), URL: http://grantome.com/grant/NIH/K08-AR061437-04, (20180302), XP055456002 [A] 1-32 * the whole document * * in particular page 2 *
 [A]  - X. X. WANG ET AL, "Increased expression of CXCR3 and its ligands in patients with vitiligo and CXCL10 as a potential clinical marker for vitiligo", BRITISH JOURNAL OF DERMATOLOGY, UK, (20160601), vol. 174, no. 6, doi:10.1111/bjd.14416, ISSN 0007-0963, pages 1318 - 1326, XP055455885 [A] 1-32 * the whole document * * in particular, apge 1323 *

DOI:   http://dx.doi.org/10.1111/bjd.14416
 [A]  - WANG XIUXIU ET AL, "Increased expression of CXCR3 and its ligands in vitiligo patients and its role as potential clinical markers for vitiligo", JOURNAL OF DERMATOLOGICAL SCIENCE, (20160604), vol. 84, no. 1, doi:10.1016/J.JDERMSCI.2016.08.306, ISSN 0923-1811, XP029754327 [A] 1-32 * abstract *

DOI:   http://dx.doi.org/10.1016/j.jdermsci.2016.08.306
 [A]  - M. RASHIGHI ET AL, "CXCL10 Is Critical for the Progression and Maintenance of Depigmentation in a Mouse Model of Vitiligo", SCIENCE TRANSLATIONAL MEDICINE, (20140212), vol. 6, no. 223, doi:10.1126/scitranslmed.3007811, ISSN 1946-6234, pages 223ra23 - 223ra23, XP055152548 [A] 1-32 * the whole document * * in particular, pages 7-8 *

DOI:   http://dx.doi.org/10.1126/scitranslmed.3007811
 [A]  - MOORE GREGORY L ET AL, "Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions", 20100301, (20100301), vol. 2, no. 2, doi:10.4161/MABS.2.2.11158, ISSN 1942-0862, pages 181 - 189, XP009143498 [A] 3-6,8-12,18-21,23-27 * the whole document * * in particular, pages 182-185 *

DOI:   http://dx.doi.org/10.4161/mabs.2.2.11158
 [A]  - LAZAR G A ET AL, "Engineered antibody Fc variants with enhanced effector function", PROCEEDINGS NATIONAL ACADEMY OF SCIENCES PNAS, NATIONAL ACADEMY OF SCIENCES, US, (20060301), vol. 103, no. 11, doi:10.1073/PNAS.0508123103, ISSN 0027-8424, pages 4005 - 4010, XP002403708 [A] 3-6,8-12,18-21,23-27 * the whole document * * in particular, page 4005 *

DOI:   http://dx.doi.org/10.1073/pnas.0508123103
 [T]  - RICHMOND JILLIAN M ET AL, "CXCR3 Depleting Antibodies Prevent and Reverse Vitiligo in Mice.", THE JOURNAL OF INVESTIGATIVE DERMATOLOGY APR 2017, (201704), vol. 137, no. 4, ISSN 1523-1747, pages 982 - 985, XP002778748 [T] * the whole document *
by applicantUS5565332
 US5589205
 US6180370
 US6193980
 US6632927
 US2004236078
 US7241877
 US7244615
 US7244832
 US7262050
 WO2009032661
 US2010061983
 US8071336
 WO2013109974
 US8865870
    - UNO et al., Endocr J, (20100000), vol. 57, pages 991 - 996
    - ROEP et al., Clin Exp Immunol, (20030000), vol. 159, pages 338 - 343
    - TANAKA et al., Diabetes, (20090000), vol. 58, pages 2285 - 2291
    - MORIMOTO et al., J Immunol, (20040000), vol. 173, pages 7017 - 7024
    - LI et al., World J Gastroenterol, (20050000), vol. 11, no. 30, pages 4750 - 4752
    - SARKAR et al., Diabetes, (20120000), vol. 61, no. 2, pages 436 - 446
    - ROTTMAN et al., Lab Invest, (20010000), vol. 81, no. 3, pages 335 - 347
    - CHEN et al., Arch Dermatol Res, (20100000), vol. 302, no. 2, pages 113 - 123
    - FRIGERIO, Nat Med, (20020000), vol. 8, pages 1414 - 1420
    - CHRISTEN et al., J Immunol, (20030000), vol. 171, pages 6838 - 6845
    - VAN HALTEREN, Diabetologia, (20050000), vol. 48, pages 75 - 82
    - ALTSCHUL, SF et al., J Mol Biol, (19900000), vol. 215, page 403
    - PEARSON et al., Proc Natl Acad Sci USA, (19880000), vol. 85, page 2444
    - JONES et al., Nature, (19860000), vol. 321, page 522
    - VERHOEYEN et al., Science, (19880000), vol. 239, page 1534
    - SIMS et al., J Immunol, (19930000), vol. 151, page 2296
    - CHOTHIA; LESK, J Mol Biol, (19870000), vol. 196, page 901
    - CARTER et al., Proc Natl Acad Sci USA, (19920000), vol. 89, page 4285
    - PRESTA et al., J Immunol, (19930000), vol. 151, page 2623
    - COLVIN et al., Mol Cell Biol, (20060000), vol. 26, pages 5838 - 5849
    - RIDGWAY, A. A. G., Mammalian Expression Vectors, Butterworths, (19880000), pages 470 - 472
    - STINCHCOMB et al., Nature, (19790000), vol. 282, page 39
    - KINGSMAN et al., Gene, (19790000), vol. 7, page 141
    - TSCHEMPER et al., Gene, (19800000), vol. 10, page 157
    - JONES, Genetics, (19770000), vol. 85, page 12
    - UPPALURI et al., Transplantation, (20080000), vol. 86, pages 137 - 147
    - "A Turbidimetric Method to Determine Visual Appearances of Protein Solutions", Brigitte Eckhardt, Technology Applications, (19940300), vol. 48, no. 2
    - HARRIS et al., J. Invest. Dermatol., (20120000), vol. 132, pages 1869 - 1876
    - AGARWAL et al., J. Invest. Dermatol., (20150000), vol. 135, pages 1080 - 1088
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.