EP3507298 - DETECTING HEPATOCELLULAR CARCINOMA [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 05.07.2024 Database last updated on 19.10.2024 | |
Former | The patent has been granted Status updated on 28.07.2023 | ||
Former | Grant of patent is intended Status updated on 15.03.2023 | ||
Former | Examination is in progress Status updated on 24.12.2021 | ||
Former | Request for examination was made Status updated on 07.06.2019 | ||
Former | The international publication has been made Status updated on 10.03.2018 | Most recent event Tooltip | 02.08.2024 | Lapse of the patent in a contracting state New state(s): BE, SI | published on 04.09.2024 [2024/36] | Applicant(s) | For all designated states Mayo Foundation for Medical Education and Research 200 First Street S.W. Rochester, MN 55905 / US | For all designated states Exact Sciences Corporation 5505 Endeavor Lane Madison, Wisconsin 53719 / US | [2023/35] |
Former [2022/23] | For all designated states Mayo Foundation for Medical Education and Research 200 First Street S.W. Rochester, MN 55905 / US | ||
For all designated states Exact Sciences Corporation 5505 Endeavor Lane Madison, Wisconsin 53719 / US | |||
Former [2019/28] | For all designated states Mayo Foundation for Medical Education and Research 200 First Street S.W. Rochester, MN 55905 / US | ||
For all designated states Exact Sciences Development Company, LLC 441 Charmany Drive Madison, Wisconsin 53719 / US | Inventor(s) | 01 /
TAYLOR, William R. c/o Mayo Foundation for Medical Education and Research 200 First Street S.W. Rochester, Minnesota 55905 / US | 02 /
AHLQUIST, David A. c/o Mayo Foundation for Medical Education and Research 200 First Street S.W. Rochester, Minnesota 55905 / US | 03 /
MAHONEY, Douglas W. c/o Mayo Foundation for Medical Education and Research 200 First Street S.W. Rochester, Minnesota 55905 / US | 04 /
KISIEL, John B. c/o Mayo Foundation for Medical Education and Research 200 First Street S.W. Rochester, Minnesota 55905 / US | 05 /
YAB, Tracy C. c/o Mayo Foundation for Medical Education and Research 200 First Street S.W. Rochester, Minnesota 55905 / US | 06 /
ALLAWI, Hatim T. c/o Exact Sciences Corporation 441 Charmany Drive Madison, Wisconsin 53719 / US | 07 /
GIAKOUMOPOULOS, Maria c/o Exact Sciences Corporation 441 Charmany Drive Madison, Wisconsin 53719 / US | 08 /
LIDGARD, Graham P. c/o Exact Sciences Corporation 441 Charmany Drive Madison, Wisconsin 53719 / US | [2019/28] | Representative(s) | Forresters IP LLP Skygarden Erika-Mann-Straße 11 80636 München / DE | [2023/35] |
Former [2019/28] | Algemeen Octrooi- en Merkenbureau B.V. P.O. Box 645 5600 AP Eindhoven / NL | Application number, filing date | 17847642.0 | 01.09.2017 | [2019/28] | WO2017US49915 | Priority number, date | US201662383165P | 02.09.2016 Original published format: US 201662383165 P | [2019/28] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2018045322 | Date: | 08.03.2018 | Language: | EN | [2018/10] | Type: | A1 Application with search report | No.: | EP3507298 | Date: | 10.07.2019 | Language: | EN | The application published by WIPO in one of the EPO official languages on 08.03.2018 takes the place of the publication of the European patent application. | [2019/28] | Type: | B1 Patent specification | No.: | EP3507298 | Date: | 30.08.2023 | Language: | EN | [2023/35] | Search report(s) | International search report - published on: | US | 08.03.2018 | (Supplementary) European search report - dispatched on: | EP | 10.02.2021 | Classification | IPC: | C12Q1/6886 | [2020/47] | CPC: |
C12Q1/6886 (EP,CN,KR,US);
C12Q1/6827 (KR);
C12Q2521/331 (KR);
C12Q2565/627 (KR);
C12Q2600/154 (EP,CN,KR,US);
C12Q2600/16 (CN,KR,US);
C12Q2600/166 (CN,KR,US)
(-)
|
Former IPC [2019/28] | C07H21/04, C12Q1/68, G06F19/00, G06F19/22 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2019/28] | Extension states | BA | Not yet paid | ME | Not yet paid | Validation states | MA | Not yet paid | MD | Not yet paid | Title | German: | ERKENNUNG EINES LEBERZELLKARZINOMS | [2019/28] | English: | DETECTING HEPATOCELLULAR CARCINOMA | [2019/28] | French: | DÉTECTION D'UN CARCINOME HÉPATOCELLULAIRE | [2019/28] | Entry into regional phase | 01.03.2019 | National basic fee paid | 01.03.2019 | Search fee paid | 01.03.2019 | Designation fee(s) paid | 01.03.2019 | Examination fee paid | Examination procedure | 01.03.2019 | Examination requested [2019/28] | 09.08.2021 | Amendment by applicant (claims and/or description) | 23.12.2021 | Despatch of a communication from the examining division (Time limit: M04) | 25.04.2022 | Reply to a communication from the examining division | 16.03.2023 | Communication of intention to grant the patent | 21.07.2023 | Fee for grant paid | 21.07.2023 | Fee for publishing/printing paid | 21.07.2023 | Receipt of the translation of the claim(s) | Divisional application(s) | EP23191397.1 / EP4293128 | Opposition(s) | 03.06.2024 | No opposition filed within time limit [2024/32] | Fees paid | Renewal fee | 27.09.2019 | Renewal fee patent year 03 | 28.09.2020 | Renewal fee patent year 04 | 27.09.2021 | Renewal fee patent year 05 | 27.09.2022 | Renewal fee patent year 06 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | AT | 30.08.2023 | CZ | 30.08.2023 | DK | 30.08.2023 | EE | 30.08.2023 | FI | 30.08.2023 | HR | 30.08.2023 | LT | 30.08.2023 | LV | 30.08.2023 | MC | 30.08.2023 | NL | 30.08.2023 | PL | 30.08.2023 | RO | 30.08.2023 | RS | 30.08.2023 | SE | 30.08.2023 | SI | 30.08.2023 | SK | 30.08.2023 | SM | 30.08.2023 | LU | 01.09.2023 | BE | 30.09.2023 | CH | 30.09.2023 | NO | 30.11.2023 | GR | 01.12.2023 | IS | 30.12.2023 | PT | 02.01.2024 | [2024/36] |
Former [2024/34] | AT | 30.08.2023 | |
CZ | 30.08.2023 | ||
DK | 30.08.2023 | ||
EE | 30.08.2023 | ||
FI | 30.08.2023 | ||
HR | 30.08.2023 | ||
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LV | 30.08.2023 | ||
MC | 30.08.2023 | ||
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PL | 30.08.2023 | ||
RO | 30.08.2023 | ||
RS | 30.08.2023 | ||
SE | 30.08.2023 | ||
SK | 30.08.2023 | ||
SM | 30.08.2023 | ||
LU | 01.09.2023 | ||
CH | 30.09.2023 | ||
NO | 30.11.2023 | ||
GR | 01.12.2023 | ||
IS | 30.12.2023 | ||
PT | 02.01.2024 | ||
Former [2024/28] | AT | 30.08.2023 | |
CZ | 30.08.2023 | ||
DK | 30.08.2023 | ||
EE | 30.08.2023 | ||
FI | 30.08.2023 | ||
HR | 30.08.2023 | ||
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PL | 30.08.2023 | ||
RO | 30.08.2023 | ||
RS | 30.08.2023 | ||
SE | 30.08.2023 | ||
SK | 30.08.2023 | ||
SM | 30.08.2023 | ||
LU | 01.09.2023 | ||
NO | 30.11.2023 | ||
GR | 01.12.2023 | ||
IS | 30.12.2023 | ||
PT | 02.01.2024 | ||
Former [2024/25] | AT | 30.08.2023 | |
CZ | 30.08.2023 | ||
DK | 30.08.2023 | ||
EE | 30.08.2023 | ||
FI | 30.08.2023 | ||
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PL | 30.08.2023 | ||
RO | 30.08.2023 | ||
RS | 30.08.2023 | ||
SE | 30.08.2023 | ||
SK | 30.08.2023 | ||
SM | 30.08.2023 | ||
LU | 01.09.2023 | ||
NO | 30.11.2023 | ||
GR | 01.12.2023 | ||
IS | 30.12.2023 | ||
PT | 02.01.2024 | ||
Former [2024/23] | AT | 30.08.2023 | |
CZ | 30.08.2023 | ||
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EE | 30.08.2023 | ||
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HR | 30.08.2023 | ||
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PL | 30.08.2023 | ||
RO | 30.08.2023 | ||
RS | 30.08.2023 | ||
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SK | 30.08.2023 | ||
SM | 30.08.2023 | ||
NO | 30.11.2023 | ||
GR | 01.12.2023 | ||
IS | 30.12.2023 | ||
PT | 02.01.2024 | ||
Former [2024/22] | AT | 30.08.2023 | |
CZ | 30.08.2023 | ||
DK | 30.08.2023 | ||
FI | 30.08.2023 | ||
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RO | 30.08.2023 | ||
RS | 30.08.2023 | ||
SE | 30.08.2023 | ||
SM | 30.08.2023 | ||
NO | 30.11.2023 | ||
GR | 01.12.2023 | ||
IS | 30.12.2023 | ||
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SM | 30.08.2023 | ||
NO | 30.11.2023 | ||
GR | 01.12.2023 | ||
IS | 30.12.2023 | ||
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RS | 30.08.2023 | ||
SE | 30.08.2023 | ||
NO | 30.11.2023 | ||
GR | 01.12.2023 | ||
IS | 30.12.2023 | ||
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LT | 30.08.2023 | ||
LV | 30.08.2023 | ||
PL | 30.08.2023 | ||
RS | 30.08.2023 | ||
SE | 30.08.2023 | ||
NO | 30.11.2023 | ||
GR | 01.12.2023 | ||
IS | 30.12.2023 | ||
Former [2024/09] | AT | 30.08.2023 | |
FI | 30.08.2023 | ||
LT | 30.08.2023 | ||
SE | 30.08.2023 | ||
NO | 30.11.2023 | ||
GR | 01.12.2023 | ||
IS | 30.12.2023 | ||
Former [2024/08] | LT | 30.08.2023 | |
NO | 30.11.2023 | ||
GR | 01.12.2023 | Documents cited: | Search | [A]US2011256538 (SU YING-HSIU [US], et al) [A] 2,7-9 * claims 1-4, 9 *; | [I]CN104762301 (UNIV WUHAN) [I] 10 * claims 1-6 *; | [A]EP2899274 (SYSMEX CORP [JP], et al) [A] 1-10* the whole document *; | [XI]US2016090634 (KISIEL JOHN B [US], et al) [X] 1,4,5,10 * paragraph [0024]; example 2 * [I] 3,6; | [X] - BRADLEY W ANDERSON ET AL, "Aberrant Methylation During Gastric Carcinogenesis: Patterns of Acquisition Using Novel Methylated DNA Markers From Whole Methylome Discovery", GASTROENTEROLOGY, (20160401), vol. 150, no. 4, doi:https://doi.org/10.1016/S0016-5085(16)32909-2, pages S863 - S864, XP055737623 [X] 1,4,5 * the whole document * DOI: http://dx.doi.org/https://doi.org/10.1016/S0016-5085(16)32909-2 | [A] - SOHACHI NANJO ET AL, "Identification of gastric cancer risk markers that are informative in individuals with past.infection", GASTRIC CANCER, SPRINGER-VERLAG, TO, (20120112), vol. 15, no. 4, doi:10.1007/S10120-011-0126-1, ISSN 1436-3305, pages 382 - 388, XP035128377 [A] 2,7-9 * table 1 * DOI: http://dx.doi.org/10.1007/s10120-011-0126-1 | [XYI] - QIU XUEPING ET AL, "Hypermethylation ofACP1,BMP4, andTSPYL5in Hepatocellular Carcinoma and Their Potential Clinical Significance", DIGESTIVE DISEASES AND SCIENCES, SPRINGER NEW YORK LLC, US, vol. 61, no. 1, doi:10.1007/S10620-015-3878-3, ISSN 0163-2116, (20150919), pages 149 - 157, (20150919), XP035905801 [X] 1,4,5 * page 151, column r, paragraph l; figures 1, 3 * [Y] 7-9 [I] 2,3,6 DOI: http://dx.doi.org/10.1007/s10620-015-3878-3 | [Y] - WENQING HUANG ET AL, "Analysis of DNA Methylation in Plasma for Monitoring Hepatocarcinogenesis", GENETIC TESTING AND MOLECULAR BIOMARKERS, United States, (20150601), vol. 19, no. 6, doi:10.1089/gtmb.2014.0292, ISSN 1945-0265, pages 295 - 302, XP055737817 [Y] 7-9 * table 2 * DOI: http://dx.doi.org/10.1089/gtmb.2014.0292 | [I] - JING SHEN ET AL, "Integrative epigenomic and genomic filtering for methylation markers in hepatocellular carcinomas", BMC MEDICAL GENOMICS, (20150610), vol. 8, no. 1, doi:10.1186/s12920-015-0105-1, XP055770789 [I] 2,3,6 * figure 3 * DOI: http://dx.doi.org/10.1186/s12920-015-0105-1 | [A] - TIAN-ZHOU ZHA ET AL, "Overexpression of HOXA1 correlates with poor prognosis in patients with hepatocellular carcinoma", TUMOR BIOLOGY, CH, (20120804), vol. 33, no. 6, doi:10.1007/s13277-012-0472-6, ISSN 1010-4283, pages 2125 - 2134, XP055771443 [A] 1-9 * figure 1; table 1 * DOI: http://dx.doi.org/10.1007/s13277-012-0472-6 | [A] - TSOU JEFFREY A ET AL, "Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma", MOLECULAR CANCER, BIOMED CENTRAL, LONDON, GB, (20071029), vol. 6, no. 1, ISSN 1476-4598, page 70, XP021036914 [A] 1-9 * table 2 * | International search | [A]US2003143606 (OLEK ALEXANDER [DE], et al); | [A]US2008039413 (MORRIS DAVID W [US], et al); | [Y]US2011287968 (WEINHAUSEL ANDREAS [AT], et al); | [A]US2014162894 (HATCHWELL ELI [GB], et al); | [XY]US2014358448 (TAI KAYA [JP], et al); | [Y]WO2016097120 (HOSPITAL CLÍNIC DE BARCELONA [ES], et al); | by applicant | US4683195 | US4683202 | US4965188 | US5011769 | US5124246 | US5288609 | US5338671 | WO9500669 | US5403711 | US5409818 | WO9515373 | US5494810 | US5508169 | US5624802 | US5639611 | US5660988 | WO9746705 | US5710264 | US5773258 | US5786146 | US5792614 | US5846717 | US5849481 | US5851770 | US5882867 | WO9928498 | US5914230 | US5958692 | US5965408 | US5985557 | US5994069 | US6001567 | US6013170 | WO0026401 | US6063573 | US6090543 | US6110684 | US6110677 | US6121001 | US6150097 | US6183960 | US6210884 | US6221583 | US6235502 | US6248229 | US6251594 | US6265171 | WO2005023091 | US6872816 | US2007202525 | US2009253142 | US7662594 | US2011256538 | US8361720 | US2016090634 | US20100946737 | US20100946745 | US20100946752 | US19390615486 | US19860614853 | US19970622490 | WO2004EP11715 |