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Extract from the Register of European Patents

EP About this file: EP3630125

EP3630125 - SENOLYTIC COMPOUNDS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  23.06.2023
Database last updated on 03.09.2024
FormerExamination is in progress
Status updated on  14.05.2021
FormerRequest for examination was made
Status updated on  06.03.2020
FormerThe international publication has been made
Status updated on  01.12.2018
Formerunknown
Status updated on  23.06.2018
Most recent event   Tooltip23.06.2023Application deemed to be withdrawnpublished on 26.07.2023  [2023/30]
Applicant(s)For all designated states
United Kingdom Research and Innovation
Polaris House
North Star Avenue
Swindon SN2 1FL / GB
[2020/15]
Inventor(s)01 / GIL, Jesus
MRC London Institute of Medical Sciences
Hammersmith Hospital Campus
Du Cane Road
London W12 0NN / GB
02 / GUERRERO, Ana
MRC London Institute of Medical Sciences
Hammersmith Hospital Campus
Du Cane Road
London W12 0NN / GB
03 / HARRANZ, Nicolas
MRC London Institute of Medical Sciences
Hammersmith Hospital Campus
Du Cane Road
London W12 0NN / GB
 [2020/15]
Representative(s)D Young & Co LLP
3 Noble Street
London EC2V 7BQ / GB
[N/P]
Former [2020/15]D Young & Co LLP
120 Holborn
London EC1N 2DY / GB
Application number, filing date18730422.525.05.2018
[2020/15]
WO2018GB51437
Priority number, dateGB2017000845626.05.2017         Original published format: GB 201708456
[2020/15]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2018215795
Date:29.11.2018
Language:EN
[2018/48]
Type: A2 Application without search report 
No.:EP3630125
Date:08.04.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 29.11.2018 takes the place of the publication of the European patent application.
[2020/15]
Search report(s)International search report - published on:EP03.01.2019
ClassificationIPC:A61K31/704, A61K31/585, A61P43/00
[2020/15]
CPC:
A61K31/704 (EP,US); A61K31/137 (US); A61K31/03 (US);
A61K31/122 (US); A61K31/18 (US); A61K31/34 (US);
A61K31/352 (US); A61K31/426 (US); A61K31/4709 (US);
A61K31/4745 (US); A61K31/475 (US); A61K31/585 (EP);
A61K38/13 (US); A61P43/00 (EP); A61K45/06 (US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/15]
TitleGerman:SENOLYTISCHE VERBINDUNGEN[2020/15]
English:SENOLYTIC COMPOUNDS[2020/15]
French:COMPOSÉS SÉNOLYTIQUES[2020/15]
Entry into regional phase12.12.2019National basic fee paid 
12.12.2019Designation fee(s) paid 
12.12.2019Examination fee paid 
Examination procedure12.12.2019Examination requested  [2020/15]
12.12.2019Date on which the examining division has become responsible
08.06.2020Amendment by applicant (claims and/or description)
14.05.2021Despatch of a communication from the examining division (Time limit: M04)
17.09.2021Reply to a communication from the examining division
18.10.2022Despatch of a communication from the examining division (Time limit: M04)
01.03.2023Application deemed to be withdrawn, date of legal effect  [2023/30]
22.03.2023Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2023/30]
Fees paidRenewal fee
19.03.2020Renewal fee patent year 03
14.05.2021Renewal fee patent year 04
20.05.2022Renewal fee patent year 05
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Cited inInternational search[X]WO2015116735  (MAYO FOUNDATION [US]) [X] 1-4,10,23-25,28,29,32-34 * claims 1,5-9,14 * * examples 1-17 *;
 [X]WO2015116740  (BUCK INST FOR RES ON AGING [US], et al) [X] 1-4,10,23-25,28,29,32-34 * claims 1,14-22,96-109 * * examples 1-32 *;
 [X]  - SCHMITT ROLAND ED - PETERSEN OLE ET AL, "Senotherapy: growing old and staying young?", PFLUEGERS ARCHIV: EUROPEAN JOURNAL OF PHYSIOLOGY, SPRINGER VERLAG, BERLIN, DE, vol. 469, no. 9, doi:10.1007/S00424-017-1972-4, ISSN 0031-6768, (20170407), pages 1051 - 1059, (20170407), XP036295313 [X] 1-4,10,23-25,28,29,32-34 * table 2 *

DOI:   http://dx.doi.org/10.1007/s00424-017-1972-4
 [X]  - SAMARAWEERA LELEESHA ET AL, "A Novel Indication for Panobinostat as a Senolytic Drug in NSCLC and HNSCC", SCIENTIFIC REPORTS, (20170515), vol. 7, XP002783686 [X] 1-4,10,23-25,28,29,32-34 * page 1, abstract *
 [X]  - WANG YINGYING ET AL, "Discovery of piperlongumine as a potential novel lead for the development of senolytic agents", AGING-US, (201611), vol. 8, no. 11, ISSN 1945-4589, pages 2915 - 2926, XP002783687 [X] 1-4,10,23-25,28,29,32-34 * page 2915, abstract *

DOI:   http://dx.doi.org/10.18632/aging.101100
 [X]  - ZHOU-JI ZHANG ET AL, "Bufalin attenuates the stage and metastatic potential of hepatocellular carcinoma in nude mice", JOURNAL OF TRANSLATIONAL MEDICINE, BIOMED CENTRAL, (20140228), vol. 12, no. 1, doi:10.1186/1479-5876-12-57, ISSN 1479-5876, page 57, XP021180945 [X] 1,2,4,10,23,28,29,32,34 * page 57, abstract *

DOI:   http://dx.doi.org/10.1186/1479-5876-12-57
 [X]  - WU SHIN-HWAR ET AL, "Bufalin Induces Cell Death in Human Lung Cancer Cells through Disruption of DNA Damage Response Pathways", AMERICAN JOURNAL OF CHINESE MEDICINE, (2014), vol. 42, no. 3, pages 729 - 742, XP009507297 [X] 1,2,4,10,23,28,29,32,34 * page 729, abstract *

DOI:   http://dx.doi.org/10.1142/S0192415X14500475
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.