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Extract from the Register of European Patents

EP About this file: EP3655434

EP3655434 - MONO AND BISPECIFIC ANTIBODY BINDING TO HERG1 AND HERG1/INTEGRIN BETA 1 [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  15.03.2024
Database last updated on 10.07.2024
FormerRequest for examination was made
Status updated on  24.04.2020
FormerThe international publication has been made
Status updated on  26.01.2019
Formerunknown
Status updated on  01.08.2018
Most recent event   Tooltip12.06.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Universita' Degli Studi di Firenze
Piazza San Marco, 4
50121 Firenze / IT
For all designated states
DI.V.A.L. Toscana S.R.L.
Via Madonna del Piano 6
50019 Sesto Fiorentino / IT
[2020/22]
Inventor(s)01 / ARCANGELI, Annarosa
Via G. del Pian dei Carpini 96/1
50127 Firenze / IT
02 / DURANTI, Claudia
Via Ghiberti 120
50065 Pontassieve / IT
03 / CARRARESI, Laura
Via G. Cavalcanti 32
50133 Firenze / IT
04 / CRESCIOLI, Silvia
Via delle Panche 40
50141 Firenze / IT
 [2020/22]
Representative(s)Valenza, Silvia, et al
Notarbartolo & Gervasi S.p.A.
Viale Achille Papa, 30
20149 Milano / IT
[N/P]
Former [2020/22]Valenza, Silvia, et al
Notarbartolo & Gervasi S.p.A. Corso di Porta Vittoria 9
20122 Milano / IT
Application number, filing date18742941.029.06.2018
[2020/22]
WO2018EP67641
Priority number, dateIT2017008363721.07.2017         Original published format: IT201700083637
[2020/22]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019015936
Date:24.01.2019
Language:EN
[2019/04]
Type: A1 Application with search report 
No.:EP3655434
Date:27.05.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 24.01.2019 takes the place of the publication of the European patent application.
[2020/22]
Search report(s)International search report - published on:EP24.01.2019
ClassificationIPC:C07K16/28, C07K16/30, A61P35/00
[2020/22]
CPC:
C07K16/28 (EP,EA,KR,US); A61P35/00 (EP,EA,KR,US); C07K16/2842 (EP,EA,KR,US);
C07K16/30 (EP,EA,KR); A61K2039/505 (EP,EA,KR,US); C07K2317/31 (EP,EA,KR,US);
C07K2317/56 (US); C07K2317/622 (US); C07K2317/626 (EP,EA,KR,US);
C07K2317/73 (EP,EA,KR); C07K2317/90 (EP,EA,KR); C07K2319/00 (EP,EA,KR) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/22]
TitleGerman:AN HERG1 UND HERG1/INTEGRIN BETA 1 BINDENDE MONO- UND BISPEZIFISCHE ANTIKÖRPER[2020/22]
English:MONO AND BISPECIFIC ANTIBODY BINDING TO HERG1 AND HERG1/INTEGRIN BETA 1[2020/22]
French:ANTICORPS MONO ET BISPÉCIFIQUE SE LIANT À HERG1 ET HERG1/INTÉGRINE BÊTA 1[2020/22]
Entry into regional phase21.02.2020National basic fee paid 
21.02.2020Designation fee(s) paid 
21.02.2020Examination fee paid 
Examination procedure21.02.2020Examination requested  [2020/22]
21.02.2020Date on which the examining division has become responsible
03.09.2020Amendment by applicant (claims and/or description)
15.03.2024Despatch of a communication from the examining division (Time limit: M04)
Fees paidRenewal fee
29.06.2020Renewal fee patent year 03
30.11.2021Renewal fee patent year 04
13.05.2022Renewal fee patent year 05
12.05.2023Renewal fee patent year 06
12.06.2024Renewal fee patent year 07
Penalty fee
Additional fee for renewal fee
30.06.202104   M06   Fee paid on   30.11.2021
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Cited inInternational search[AD]WO2016020483  (UNIV FIRENZE [IT], et al) [AD] 5-10,14-17 * the whole document *;
 [I]  - ZANIERI ET AL., "beta1integrin/hERG1 complex as a novel molecular target for antineoplastic therapy", ABCD CONGRESS 2011 RAVENNA, (20110908), page 58, XP002779496 [I] 1-4,11-17 * the whole document *
 [I]  - EPIGENTEK, "HERG1 Monoclonal Antibody [A12]", INTERNET CITATION, page 1, URL: http://www.epigentek.com/catalog/herg1-monoclonal-antibody-a12-p-3957.html?currency=gb&height=190&width=500&border=1&modal=true&random=1431503689546, (20150415), XP002739553 [I] 5-10,14-17 * the whole document *
 [IA]  - ANDREA BECCHETTI ET AL, "The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression", SCIENCE SIGNALING, US, (20170404), vol. 10, no. 473, doi:10.1126/scisignal.aaf3236, ISSN 1945-0877, page eaaf3236, XP055461474 [I] 5-10,14-17 * the whole document * [A] 1-4,11,12

DOI:   http://dx.doi.org/10.1126/scisignal.aaf3236
 [T]  - C DURANTI ET AL, "Po-317 a novel bispecific antibody to harness the herg1-[beta]1 macromolecular complex for cancer therapy.", TUMOUR ANGIOGENESIS, doi:10.1136/esmoopen-2018-EACR25.830, (20180629), pages A352.2 - A352, URL: https://esmoopen.bmj.com/content/3/Suppl_2/A352.2, XP055505546 [T] * the whole document *

DOI:   http://dx.doi.org/10.1136/esmoopen-2018-EACR25.830
by applicantIT1367861
 WO2016020483
    - BECCHETTI A. et al., Sci.Signaling, vol. 10, no. 473, page eaaf3236
    - ARROYO et al., J. Cell Biol., (19920000), vol. 117, no. 3, pages 659 - 670
    - MARTIN-PADURA et al., J. Biol. Chem., (19940000), vol. 269, no. 8, pages 6124 - 6132
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.