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Extract from the Register of European Patents

EP About this file: EP3573632

EP3573632 - TUMOR SELECTIVE TATA-BOX AND CAAT-BOX MUTANT ONCOLYTIC VIRUSES [Right-click to bookmark this link]
Former [2019/49]TUMOR SELECTIVE TATA-BOX AND CAAT-BOX MUTANTS
[2024/12]
StatusThe patent has been granted
Status updated on  05.07.2024
Database last updated on 20.07.2024
FormerGrant of patent is intended
Status updated on  28.02.2024
FormerExamination is in progress
Status updated on  15.10.2021
FormerRequest for examination was made
Status updated on  01.11.2019
FormerThe international publication has been made
Status updated on  04.08.2018
Most recent event   Tooltip05.07.2024(Expected) grantpublished on 07.08.2024 [2024/32]
Applicant(s)For all designated states
EpicentRx, Inc.
11099 North Torrey Pines Road
Suite 160
La Jolla, California 92037 / US
[2019/49]
Inventor(s)01 / REID, Tony, R.
5517 Carriage Court
San Diego CA 92130 / US
02 / ORONSKY, Bryan, T.
28540 Matadero Creek Lane
Los Altos Hills CA 94022 / US
03 / HEDJRAN, Farah
4445 Eastgate Mall
Suite 200
San Diego CA 92121 / US
04 / LARSON, Christopher
3815 Lebon Dr. Apt. 335
San Diego CA 92122 / US
 [2019/49]
Representative(s)Graham Watt & Co LLP
St. Botolph's House
7-9 St. Botolph's Road
Sevenoaks TN13 3AJ / GB
[2019/49]
Application number, filing date18744813.930.01.2018
[2019/49]
WO2018US16025
Priority number, dateUS201762452075P30.01.2017         Original published format: US 201762452075 P
[2019/49]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018140970
Date:02.08.2018
Language:EN
[2018/31]
Type: A1 Application with search report 
No.:EP3573632
Date:04.12.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 02.08.2018 takes the place of the publication of the European patent application.
[2019/49]
Type: B1 Patent specification
No.:EP3573632
Date:07.08.2024
Language:EN
[2024/32]
Search report(s)International search report - published on:AU02.08.2018
(Supplementary) European search report - dispatched on:EP26.08.2020
ClassificationIPC:C07K14/535, C12N15/86, A61K35/76, A61P35/00, C12N7/00, A61K35/761
[2024/12]
CPC:
A61K35/76 (EP,EA,KR); C12N7/00 (EP,EA,KR); C12N15/86 (EP,EA,KR,US);
A61K35/761 (EP,EA,US); A61K48/00 (KR); A61P1/04 (EP);
A61P1/16 (EP); A61P1/18 (EP); A61P11/00 (EP);
A61P11/06 (EP); A61P13/08 (EP); A61P13/10 (EP);
A61P13/12 (EP); A61P15/00 (EP); A61P17/00 (EP);
A61P17/06 (EP); A61P19/02 (EP); A61P19/08 (EP);
A61P25/00 (EP); A61P27/02 (EP); A61P29/00 (EP);
A61P35/00 (EP,KR); A61P35/02 (EP); A61P37/06 (EP);
A61P43/00 (EP); A61P7/02 (EP); A61P9/10 (EP);
A61P9/12 (EP); C07K14/535 (EP); C12N2710/10321 (EP,EA,KR,US);
C12N2710/10332 (EP,EA,KR,US); Y02A50/30 (EP,EA) (-)
Former IPC [2020/39]A61K35/76, C12N15/86, A61K35/761, A61P35/00, C12N7/00
Former IPC [2019/49]A61K35/76, C12N15/86
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/49]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TNNot yet paid
TitleGerman:TUMORSELEKTIV ONKOLYTISCHES VIRUS MIT TATA-BOX- UND CAAT-BOX-MUTATIONEN[2024/12]
English:TUMOR SELECTIVE TATA-BOX AND CAAT-BOX MUTANT ONCOLYTIC VIRUSES[2024/12]
French:VIRUS ONCOLYTIQUES MUTANTS DE BOÎTE TATA ET DE BOÎTE CAAT SÉLECTIFS DE TUMEURS[2024/12]
Former [2019/49]TUMORSELEKTIVE TATA-BOX- UND CAAT-BOX-MUTANTEN
Former [2019/49]TUMOR SELECTIVE TATA-BOX AND CAAT-BOX MUTANTS
Former [2019/49]MUTANTS DE BOÎTE TATA ET DE BOÎTE CAAT SÉLECTIFS DE TUMEURS
Entry into regional phase28.08.2019National basic fee paid 
28.08.2019Search fee paid 
28.08.2019Designation fee(s) paid 
28.08.2019Examination fee paid 
Examination procedure28.08.2019Examination requested  [2019/49]
25.03.2021Amendment by applicant (claims and/or description)
14.10.2021Despatch of a communication from the examining division (Time limit: M04)
21.02.2022Reply to a communication from the examining division
16.11.2022Despatch of a communication from the examining division (Time limit: M04)
08.03.2023Reply to a communication from the examining division
08.02.2024Cancellation of oral proceeding that was planned for 15.03.2024
29.02.2024Communication of intention to grant the patent
15.03.2024Date of oral proceedings (cancelled)
01.07.2024Fee for grant paid
01.07.2024Fee for publishing/printing paid
01.07.2024Receipt of the translation of the claim(s)
Fees paidRenewal fee
27.02.2020Renewal fee patent year 03
12.02.2021Renewal fee patent year 04
16.12.2021Renewal fee patent year 05
14.12.2022Renewal fee patent year 06
14.12.2023Renewal fee patent year 07
Penalty fee
Additional fee for renewal fee
31.01.202003   M06   Fee paid on   27.02.2020
31.01.202104   M06   Fee paid on   12.02.2021
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Documents cited:Search[E]WO2018218240  (EPICENTRX INC [US])
International search[X]WO2010086838  (ONCOS THERAPEUTICS [FI], et al) [X] 1-19, 21-28, 31-36, 38-39, 41-42, 44-77, 79 & 85-87 * Abstract, Figure 3, pages 6, 14, 19-21 & 24 *;
 [XA]WO2010101921  (UNIV CALIFORNIA [US], et al) [X] 38-39, 41-50, 63-76 & 85-87 * Figure 4, pages 4, 13, 39 & 44 page 39 * [A] 50;
 [X]EP3006566  (ONCOS THERAPEUTICS LTD [FI]) [X] 21-28, 35-36, 38-39, 41-42, 44-76 & 85-87 * Figure 1, pages 4, 11 & 19 *;
 [X]  - HEDJRAN F et al., "Deletion analysis of Ad5 Ela transcriptional control region: impact on tumor-selective expression of Ela and Elb", Cancer Gene Therapy, (20110000), vol. 18, pages 717 - 723, XP002679460 [X] 38-39, 41-50, 63-76 & 85-87 * Abstract, Figure 2 & page 719 *

DOI:   http://dx.doi.org/10.1038/CGT.2011.41
 [A]  - HANAKA S et al., "Regulation of In Vitro and In Vivo Transcription of Early-Region IV of Adenovirus Type 5 by Multiple cis-Acting Elements", Molecular and Cellular Biology, (19870000), vol. 7, pages 2578 - 2587, XP055522845 [A] 0 * Abstract, page 2580 *

DOI:   http://dx.doi.org/10.1128/MCB.7.7.2578
 [A]  - NISHIGAKI T et al., "A Specific Domain of the Adenovirus EIV Promoter is Necessary To Maintain Susceptibility of the Integrated Promoter to EIA Transactivation", Molecular and Cellular Biology, (19880000), vol. 8, pages 353 - 360, XP055522849 [A] 0 * Abstract *

DOI:   http://dx.doi.org/10.1128/MCB.8.1.353
by applicantWO2010101921
    - KUMAR, S et al., CURRENT OPINION IN MOLECULAR THERAPEUTICS, (20080000), vol. 10, no. 4, pages 371 - 379
    - KIM, D, EXPERT OPINION ON BIOLOGICAL THERAPY, (20010000), vol. 1, no. 3, pages 525 - 538
    - KIM D, ONCOGENE, (20000000), vol. 19, no. 56, pages 6660 - 6669
    - HEDJRAN F et al., "Deletion analysis of Ad5 Ela transcriptional control region: impact on tumor-selective expression of Ela and Elb", Cancer Gene Therapy, vol. 18, pages 717 - 723
    - WU et al., NATURE, (19870000), vol. 326, no. 6112, pages 512 - 5
    - ALTSCHUL et al., NUCLEIC ACIDS RES., (19970000), vol. 25, pages 3389 - 3402
    - ALTSCHUL et al., NATURE GENETICS, (19940000), vol. 6, pages 119 - 129
    - HENIKOFF et al., PROC. NATL. ACAD. SCI. USA, (19920000), vol. 89, pages 10915 - 10919
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.