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Extract from the Register of European Patents

EP About this file: EP3668599

EP3668599 - SULFONYLUREAS AND SULFONYLTHIOUREAS AS NLRP3 INHIBITORS [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  18.03.2022
Database last updated on 24.09.2024
FormerRequest for examination was made
Status updated on  22.05.2020
FormerThe international publication has been made
Status updated on  22.02.2019
Formerunknown
Status updated on  07.09.2018
Most recent event   Tooltip20.08.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Inflazome Limited
88 Harcourt Street
Dublin 2 / IE
[2020/26]
Inventor(s)01 / COOPER, Matthew
c/o Inflazome UK Limited
D6 Grain House
Mill Court
Great Shelford Cambridge CB22 5LD / GB
02 / MILLER, David
c/o Inflazome UK Limited
D6 Grain House
Mill Court
Great Shelford Cambridge CB22 5LD / GB
03 / MACLEOD, Angus
c/o Inflazome UK Limited
D6 Grain House
Mill Court
Great Shelford Cambridge CB22 5LD / GB
04 / THOM, Stephen
c/o Sygnature Discovery Limited The Discovery Building BioCity
Pennyfoot Street
Nottingham NG1 1GR / GB
05 / ST-GALLAY, Stephen
c/o Sygnature Discovery Limited The Discovery Building BioCity
Pennyfoot Street
Nottingham NG1 1GR / GB
06 / SHANNON, Jonathan
c/o Sygnature Discovery Limited The Discovery Building BioCity
Pennyfoot Street
Nottingham NG1 1GR / GB
07 / ALANINE, Thomas
c/o Sygnature Discovery Limited The Discovery Building BioCity
Pennyfoot Street
Nottingham NG1 1GR / GB
08 / ONIONS, Stuart
c/o Sygnature Discovery Limited The Discovery Building BioCity
Pennyfoot Street
Nottingham NG1 1GR / GB
09 / STRUTT, Ian
c/o Sygnature Discovery Limited The Discovery Building BioCity
Pennyfoot Street
Nottingham NG1 1GR / GB
10 / CARRILLO ARREGUI, Jokin
c/o Sygnature Discovery Limited The Discovery Building BioCity
Pennyfoot Street
Nottingham NG1 1GR / GB
 [2020/26]
Representative(s)Bernard, Guillaume
F. Hoffmann-La Roche AG
Patent Department
Grenzacherstrasse 124
4070 Basel / CH
[N/P]
Former [2020/26]Johnson, Stephen William, et al
Venner Shipley LLP Byron House Cambridge Business Park Cowley Road
Cambridge CB4 0WZ / GB
Application number, filing date18759274.615.08.2018
[2020/26]
WO2018EP72119
Priority number, dateGB2017001308215.08.2017         Original published format: GB 201713082
GB2017001856309.11.2017         Original published format: GB 201718563
GB2017002173122.12.2017         Original published format: GB 201721731
GB2017002172622.12.2017         Original published format: GB 201721726
GB2018001098304.07.2018         Original published format: GB 201810983
[2020/26]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019034690
Date:21.02.2019
Language:EN
[2019/08]
Type: A1 Application with search report 
No.:EP3668599
Date:24.06.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 21.02.2019 takes the place of the publication of the European patent application.
[2020/26]
Search report(s)International search report - published on:EP21.02.2019
ClassificationIPC:A61P31/00, A61P25/28, A61P29/00, A61P35/00, A61P3/10, C07D231/18, C07D233/84, C07D401/04, C07D401/12, C07D403/04, C07D403/06, C07D403/12, C07D405/04, C07D405/12, C07D413/06, C07D417/04, C07D249/04, C07D249/12, C07D471/04, C07D487/04
[2020/26]
CPC:
C07D231/18 (EP,KR,US); C07D487/04 (EP,KR,US); A61K31/415 (KR);
A61K31/4155 (KR); A61K31/4418 (EP); A61K31/4427 (EP);
A61K31/4433 (EP); A61K31/4439 (EP,KR); A61K31/444 (EP);
A61K31/445 (EP); A61K31/4985 (KR); A61K31/506 (KR);
A61K31/5377 (EP,KR); A61K45/06 (EP,KR,US); A61P25/00 (EP,KR);
A61P25/28 (EP,KR); A61P29/00 (EP,KR); A61P3/10 (EP,KR);
A61P31/00 (EP,KR); A61P35/00 (EP,KR); A61P37/00 (EP,KR);
C07D213/36 (EP,KR); C07D213/44 (EP,KR); C07D213/64 (EP,KR,US);
C07D233/84 (EP,KR); C07D249/04 (EP,KR,US); C07D249/12 (EP,KR,US);
C07D401/04 (EP,US); C07D401/12 (EP,KR,US); C07D401/14 (EP,KR);
C07D403/04 (EP,KR); C07D403/06 (EP,KR,US); C07D403/12 (EP,KR);
C07D405/04 (EP,KR); C07D405/12 (EP,KR,US); C07D405/14 (EP,KR,US);
C07D413/06 (EP,KR,US); C07D417/04 (EP,KR,US); C07D471/04 (EP,KR) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/26]
Extension statesBA27.02.2020
ME27.02.2020
Validation statesKH27.02.2020
MA27.02.2020
MD27.02.2020
TN27.02.2020
TitleGerman:SULFONYLHARNSTOFFE UND SULFONYLTHIOHARNSTOFFE ALS NLRP3-INHIBITOREN[2020/26]
English:SULFONYLUREAS AND SULFONYLTHIOUREAS AS NLRP3 INHIBITORS[2020/26]
French:SULFONYLUREÉS ET SULFONYLTHIOUREÉS EN TANT QU'INHIBITEURS DE NLRP3[2020/26]
Entry into regional phase27.02.2020National basic fee paid 
27.02.2020Designation fee(s) paid 
27.02.2020Examination fee paid 
Examination procedure27.02.2020Examination requested  [2020/26]
27.02.2020Date on which the examining division has become responsible
26.10.2020Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
04.01.2021Amendment by applicant (claims and/or description)
23.03.2022Despatch of a communication from the examining division (Time limit: M08)
28.11.2022Reply to a communication from the examining division
Request for further processing for:04.01.2021Request for further processing filed
04.01.2021Full payment received (date of receipt of payment)
Request granted
20.01.2021Decision despatched
Fees paidRenewal fee
24.08.2020Renewal fee patent year 03
17.08.2021Renewal fee patent year 04
09.08.2022Renewal fee patent year 05
22.08.2023Renewal fee patent year 06
20.08.2024Renewal fee patent year 07
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Cited inInternational search[XA]US4802908  (HILLEMANN CRIAG L [US]) [X] 1,2,6-8,12-14,20 * column 149 - column 150; compounds 10,11 * [A] 3-5,9-11,15-19,21-29;
 [XI]WO0119390  (PFIZER PROD INC [US], et al) [X] 1,2,6,7,12-16,18-20,22-24,26,27 * the whole document * * in particular abstract and compounds with the Registry Number 210826-34-9 and 210826-45-2 * [I] 3-5,8-11,17,21,25,28,29;
 [XI]WO2006085815  (ASTRAZENECA AB [SE], et al) [X] 1-8,10-14,17,20,22-24,26,27 * the whole document * * in particular examples 11, 12, 16, 19, 24, 37 and 38 * [I] 9,15,16,18,19,21,25,28,29;
 [XA]EP2781216  (KYOWA HAKKO KIRIN CO LTD [JP]) [X] 1,3-5,10,12,13,22-24,26,27 * the whole document * * in particular paragraph [0001] and compounds with the Registry Number 1333213-87-8 and 1333214-09-7 * [A] 2,6-9,11,14-21,25,28,29;
 [XDI]WO2016131098  (UNIV QUEENSLAND [AU], et al) [XD] 1-8,11-16,18-20,22-29 * the whole document * * in particular abstract, claims (see claim 36) and pages 42, 46, 173, 213, 255, 280 * [I] 9,10,17,21;
 [IDP]WO2017140778  (UNIV QUEENSLAND [AU], et al) [IDP] 1-29 * the whole document * * in particular the abstract, the examples, the claims, and on page 69 the 6th, 8th and 10th compound *;
 [XDPI]WO2017184604  (IFM THERAPEUTICS INC [US], et al) [XDP] 1,2,7,8,11-15,18-20,22-29 * the whole document * * in particular abstract, and compound 213 on page 256 and claim 122 * [I] 3-6,9,10,16,17,21;
 [XDPI]WO2018136890  (JECURE THERAPEUTICS INC [US]) [XDP] 1,3-5,10-16,18-29 * the whole document * * in particular abstract, specific compounds on pages 148, 151, 152, 154, 159, 189, 190, 191, 193, 347, 350, examples 60-66 and claims 65 and 66 * [I] 2,6-9;
 [XA]  - "Acetamide, N-[5-[[[[(2,5-dioxo-4-imidazolidinyl)amino]carbonyl]amino]sulfonyl]-4-methyl-2-thiazolyl-", REGISTRY, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, (20060920), XP002785020 [X] 1,2,6,7,12,13,20 * Compound with the Registry Number 907958-32-1 * [A] 3-5,8-11,14-19,21-29
 [XA]  - "1H-1,2,4-Triazole-1-carboxamide, N-(2-chlorophenyl)-5-[[[[(2-chlorophenyl)amino]carbonyl]amino]sulfonyl]-", REGISTRY, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, (20040315), XP002785021 [X] 1-8,12-14,20 * Compound with the Registry Number 663215-37-0 * [A] 9-11,15-19,21-29
 [XA]  - YOUSSEF, KHAIRIA M.; AL-ABDULLAH, EBTIHAL; EL-KHAMEES, HAMAD, "Synthesis of sulofenur analogs as antitumour agents: Part II", MEDICINAL CHEMISTRY RESEARCH, (2003), vol. 11, no. 9, ISSN 1054-2523, pages 481 - 503, XP009509405 [X] 1,2,6,7,12,13,20,24,26,27 * abstract * * page 491; table 2; compound 28 * [A] 3-5,8-11,14-19,21-23,25,28,29
 [XA]  - Youssef, Khairia M.; Shouman, Samia, "N1,N3-Diaryl sulfonylureas as possible anticancer agents", CAPLUS, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, (1995), Database accession no. 123:339790, XP002786579 [X] 1,2,6,7,12,13,20,24,26,27 * abstract * * Compound with the Registry Number 170648-58-5 * [A] 3-5,8-11,14-19,21-23,25,28,29
 [XA]  - Zimmerman, William T., "Preparation of herbicidal sulfonylureas.", CAPLUS, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, (1995), Database accession no. 122:49104, XP002786580 [X] 1,3,5,10,12-14,20 * abstract * * Compound with the Registry Number 1238307-74-8 * [A] 2,4,6-9,11,15-19,21-29
 [XA]  - Yamamoto, Susumu; Kakuta, Takuya; Sato, Toshiaki; Morimoto, Katsushi; Oya, Eiichi; Ikai, Takashi; Nawamaki, Tsutomu, "Pyrazolesulfonamides and herbicides containing them", CAPLUS, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, (1986), Database accession no. 105:191075, XP002786581 [X] 1-7,11-14,20 * abstract * * Compound with the Registry Number 104843-72-3 * [A] 8-10,15-19,21-29
 [XA]  - Ouf, A. A. Abou; El-Kerdawy, M. M.; Farghaly, A. M.; Gad, L. M., "Sulfonyl ureas and thioureas of 1,3,4-thiadiazole to be tested as hypoglycemic agents", CAPLUS, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, (1983), Database accession no. 98:107226, XP002786582 [X] 1,2,4,6,7,12-14,20,24,26 * abstract * * Compounds with the Registry Number 884884-72-0, 84884-75-3, 84884-76-4, 84884-82-2 and 84884-90-2 * [A] 3,5,8-11,15-19,21-23,25,27-29
 [XA]  - "Hypoglycemic acylaminoalkylthiophenesulfonylureas", CAPLUS, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, (1972), Database accession no. 77:5318, XP002786583 [X] 1,2,12,13,20,22-24,26 * abstract * * Compound with the Registry Number 36628-63-4 * [A] 3-11,14-19,21,25,27-29
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.