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Extract from the Register of European Patents

EP About this file: EP3697414

EP3697414 - USE OF CLOXACILLIN TO INHIBIT/PREVENT BIOFILM FORMATION [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  26.05.2023
Database last updated on 19.10.2024
FormerRequest for examination was made
Status updated on  24.07.2020
FormerThe international publication has been made
Status updated on  26.04.2019
Formerunknown
Status updated on  12.09.2018
Most recent event   Tooltip26.05.2023Application deemed to be withdrawnpublished on 28.06.2023  [2023/26]
Applicant(s)For all designated states
Biofilm Control
Biopôle Clermont-Limagne
63360 Saint-Beauzire / FR
[2020/35]
Inventor(s)01 / PROVOT, Christian
25 rue du Grand Champ
63670 Le Cendre / FR
02 / BERNARDI, Thierry
26 rue de Sarliève
63170 Perignat les Sarlieve / FR
 [2020/35]
Representative(s)Novagraaf Technologies
Bâtiment O2
2, rue Sarah Bernhardt
CS90017
92665 Asnières-sur-Seine Cedex / FR
[2020/35]
Application number, filing date18762363.223.07.2018
[2020/35]
WO2018FR51880
Priority number, dateFR2017005978318.10.2017         Original published format: FR 1759783
[2020/35]
Filing languageFR
Procedural languageFR
PublicationType: A1 Application with search report
No.:WO2019077211
Date:25.04.2019
Language:FR
[2019/17]
Type: A1 Application with search report 
No.:EP3697414
Date:26.08.2020
Language:FR
The application published by WIPO in one of the EPO official languages on 25.04.2019 takes the place of the publication of the European patent application.
[2020/35]
Search report(s)International search report - published on:EP25.04.2019
ClassificationIPC:A61K31/431, A61P31/04
[2020/35]
CPC:
A61K31/431 (EP,US); A61P31/04 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/35]
TitleGerman:VERWENDUNG VON CLOXACILLIN ZUR VERHINDERUNG/HEMMUNG VON BIOFILMBILDUNG[2020/35]
English:USE OF CLOXACILLIN TO INHIBIT/PREVENT BIOFILM FORMATION[2020/35]
French:UTILISATION DE LA CLOXACILLINE POUR INHIBER/ EMPECHER LA FORMATION DE BIOFILM[2020/35]
Entry into regional phase03.04.2020National basic fee paid 
03.04.2020Designation fee(s) paid 
03.04.2020Examination fee paid 
Examination procedure03.04.2020Examination requested  [2020/35]
03.04.2020Date on which the examining division has become responsible
05.11.2020Amendment by applicant (claims and/or description)
01.02.2023Application deemed to be withdrawn, date of legal effect  [2023/26]
17.02.2023Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2023/26]
Fees paidRenewal fee
30.07.2020Renewal fee patent year 03
23.07.2021Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
31.07.202205   M06   Not yet paid
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[XY]WO2014155020  (BIOFILM CONTROL [FR]) [X] 1-11 * page 1, lines 5-15 * * pages 18-19, lines 21-14 * * page 20, line 12 - page 21, line 8 * * page 23, line 28 - page 24, line 2 * [Y] 1-11;
 [X]  - JASON TASSE ET AL, "Preliminary results of a new antibiotic susceptibility test against biofilm installation in device-associated infections: the Antibiofilmogram", PATHOGENS AND DISEASE, GB, (20160801), vol. 74, no. 6, doi:10.1093/femspd/ftw057, ISSN 2049-632X, page ftw057, XP055479076 [X] 1-11 * the whole document *

DOI:   http://dx.doi.org/10.1093/femspd/ftw057
 [X]  - Jason Tasse, "Apport de l'Antibiofilmogramme et de la mesure de la capacité de formation du biofilm dans la prise en charge des infections osteo-articulaires a staphylocoques", France, (20170706), URL: http://www.crioac-lyon.fr/Documents/Theses/Tasse_these.pdf, (20180529), XP055479094 [X] 1-11 * the whole document * * pages 90-92 * * pages 94-105 * * pages 135-147 *
 [Y]  - Merle E Olson ET AL, "Biofilm bacteria: formation and comparative susceptibility to antibiotics", Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire, Canada, (20020401), pages 86 - 92, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC226988/pdf/20020400s00004p86.pdf, (2002), XP055479203 [Y] 1-11 * the whole document *
by applicant   - COSTERTON et al., "Bacterial Biofilms : a common cause of persistent infections", Science, (19990000), vol. 284, doi:doi:10.1126/science.284.5418.1318, pages 1318 - 1322, XP002954870

DOI:   http://dx.doi.org/10.1126/science.284.5418.1318
    - HOIBY, N. et al., "Antibiotic résistance of bacterial biofilms", International Journal of Antimicrobial Agents, (20100000), vol. 35, doi:doi:10.1016/j.ijantimicag.2009.12.011, pages 322 - 332, XP026915279

DOI:   http://dx.doi.org/10.1016/j.ijantimicag.2009.12.011
    - MORGENSTERN et al., J Orthop Res, (20161100), vol. 34, no. 11, pages 1905 - 1913
    - TUNNEY et al., J Orthop Res, (20070100), vol. 25, no. 1, pages 2 - 10
    - TROUILLET-ASSANT et al., Cell Microbiol., (20161000), vol. 18, no. 10, pages 1405 - 14
    - VALOUR, BMC Infect Dis., (20140816), vol. 14, page 44
    - HOFFMAN et al., Nature, (20050000), vol. 436, pages 1171 - 1175
    - VUOTTO et al., Pathod Dis, (20160000), page 74
    - MLYNEK et al., Antimicrob Agents Chemother., (20160000), vol. 60, pages 2639 - 51
    - MIRANI et al., J Basic Microbiol., (20110000), vol. 51, pages 191 - 5
    - KAPLAN, Int J Artif Organs, (20110000), vol. 34, pages 737 - 751
    - VALOUR, BMC Infect Dis, (20140816), vol. 14, page 44
    - JONSSON et al., "Cloxacillin concentrations in serum, subcutaneous fat, and muscle in patients with chronic critical limb ischemia", Eur J Clin Pharmacol, (20140000), vol. 70, no. 8, pages 957 - 63
    - MORGENSTERN et al., "Biofilm formation increases treatment failure in Staphylococcus epidermidis device-related osteomyelitis of the lower extremity in human patients", J Orthop Res., (20161100), vol. 34, no. 11, pages 1905 - 1913
    - TUNNEY et al., "Biofilm Formation by Bacteria Isolated from Retrieved Failed Prosthetic Hip Implants in an In Vitro Model of Hip Arthroplasty Antibiotic Prophylaxis", J Orthop Res., (20070100), vol. 25, no. 1, pages 2 - 10
    - TROUILLET-ASSANT et al., "Adaptive processes of Staphylococcus aureus isolâtes during the progression from acute to chronic bone and joint infections in patients", Cell Microbiol., (20161000), vol. 18, no. 10, pages 1405 - 14
    - VALOUR et al., "Déterminants of methicillin-susceptible Staphylococcus aureus native bone and joint infection treatment failure: a rétrospective cohort study", BMC Infect Dis., (20140816), vol. 14, doi:doi:10.1186/1471-2334-14-443, page 44, XP021192911

DOI:   http://dx.doi.org/10.1186/1471-2334-14-443
    - SINGH; MISHRA, "Synergistic and antagonistic actions of antibiotics against biofilm forming Staphylococcus aureus", Asian Journal of Plant Science and Research, (20120000), vol. 2, no. 3, pages 350 - 354
    - HOFFMAN et al., "Aminoglycoside antibiotics induce bacterial biofilm formation", Nature, (20050000), vol. 436, pages 1171 - 1175
    - VUOTTO et al., "Sub-inhibitory concentrations of metronidazole increase biofilm formation in Clostridium difficile strains", Pathod Dis, (20160000), page 74
    - MLYNEK et al., "Effects of Low-Dose Amoxicillin on Staphylococcus aureus USA300 Biofilms", Antimicrob Agents Chemother., (20160000), vol. 60, pages 2639 - 51
    - MIRANI et al., "Effect of sub-lethal doses of vancomycin and oxacillin on biofilm formation by vancomycin intermediate résistant Staphylococcus aureus", J Basic Microbiol., (20110000), vol. 51, pages 191 - 5
    - KAPLAN, "Antibiotic-induced biofilm formation", Int J Artif Organs, (20110000), vol. 34, pages 737 - 751
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.