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Extract from the Register of European Patents

EP About this file: EP3596082

EP3596082 - CDPK1 INHIBITORS, COMPOSITIONS AND METHODS RELATED THERETO [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  12.01.2024
Database last updated on 28.09.2024
FormerExamination is in progress
Status updated on  03.03.2023
FormerRequest for examination was made
Status updated on  20.12.2019
FormerThe international publication has been made
Status updated on  22.09.2018
Most recent event   Tooltip12.01.2024Application deemed to be withdrawnpublished on 14.02.2024  [2024/07]
Applicant(s)For all designated states
Vyera Pharmaceuticals, LLC
600 Third Avenue, 10th Floor
New York, NY 10016 / US
[2020/04]
Inventor(s)01 / HOPPER, Allen, T.
75 Adams St.
Lexington MA 02420 / US
 [2020/04]
Representative(s)HGF
HGF Limited
1 City Walk
Leeds LS11 9DX / GB
[N/P]
Former [2020/04]HGF Limited
4th Floor
Merchant Exchange
17-19 Whitworth Street West
Manchester M1 5WG / GB
Application number, filing date18767756.215.03.2018
[2020/04]
WO2018US22595
Priority number, dateUS201762471795P15.03.2017         Original published format: US 201762471795 P
[2020/04]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018170236
Date:20.09.2018
Language:EN
[2018/38]
Type: A1 Application with search report 
No.:EP3596082
Date:22.01.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 20.09.2018 takes the place of the publication of the European patent application.
[2020/04]
Search report(s)International search report - published on:IL20.09.2018
(Supplementary) European search report - dispatched on:EP18.11.2020
ClassificationIPC:C07D487/04, A61K31/519, A61P33/02, A61P31/06
[2020/04]
CPC:
A61P31/06 (EP); C07D487/04 (EP,US); A61P33/02 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/04]
TitleGerman:CDPK1-INHIBITOREN, ZUSAMMENSETZUNGEN UND VERFAHREN IM ZUSAMMENHANG DAMIT[2020/04]
English:CDPK1 INHIBITORS, COMPOSITIONS AND METHODS RELATED THERETO[2020/04]
French:INHIBITEURS DE CDPK1, COMPOSITIONS ET PROCÉDÉS ASSOCIÉS[2020/04]
Entry into regional phase20.09.2019National basic fee paid 
20.09.2019Search fee paid 
20.09.2019Designation fee(s) paid 
20.09.2019Examination fee paid 
Examination procedure20.09.2019Examination requested  [2020/04]
08.06.2021Amendment by applicant (claims and/or description)
07.03.2023Despatch of a communication from the examining division (Time limit: M06)
19.09.2023Application deemed to be withdrawn, date of legal effect  [2024/07]
11.10.2023Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2024/07]
Fees paidRenewal fee
12.03.2020Renewal fee patent year 03
12.03.2021Renewal fee patent year 04
18.02.2022Renewal fee patent year 05
14.02.2023Renewal fee patent year 06
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Documents cited:Search[X]  - THERESA B. KUHLENSCHMIDT ET AL, "ABSTRACT", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, US, (20151109), vol. 60, no. 1, doi:10.1128/AAC.01915-15, ISSN 0066-4804, pages 570 - 579, XP055695132 [X] 1,2,4,9-11,14,15 * page 572; compound 5 * * page 573; table 1 *

DOI:   http://dx.doi.org/10.1128/AAC.01915-15
International search[X]WO2009062118  (FOLDRX PHARMACEUTICALS INC [US], et al) [X] 1-8, 10, 11, 14-19, 27, 28, 33 * Compounds 73, 74, 77, 113, 221, 228, 253 and 314. *;
 [X]US2012077827  (IBRAHIM PRABHA N [US], et al) [X] 1-4, 6-8, 14-18, 27, 28, 33 * Compounds la-lc, 2a-2d, 3a-3d, 4a-4d and more. *;
 [X]WO2006068760  (UNIV CALIFORNIA [US], et al) [X] 1, 2, 4, 6, 14, 16, 18, 27 * Compound 63 *;
 [X]WO2010045542  (UNIV CALIFORNIA [US], et al) [X] 1, 2, 4, 6, 14, 16, 18, 27 * Intermediate compounds on page 59 lines 22-23 and 26-27, as well as final products BB9 and BB 10/cmpd3. *;
 [X]WO2011153553  (UNIV CALIFORNIA [US], et al) [X] 1, 2, 4, 6, 14, 16, 18, 27, 28, 33 * Example 28, compounds 38 and 17. *;
 [X]WO2013010136  (PHARMACYCLICS INC [US], et al) [X] 1-4, 10, 14, 16-18, 27 * Page 64 and more. *;
 [X]US2013018040  (VAN VOORHIS WESLEY C [US], et al) [X] 1-37 * See [0008], [0233], [0617]-[0619], formulae (lb), (IIc) and (He), compounds 5f (page 30) and 13 (page 38), *;
 [X]  - OKUZUMI T et al., "Synthesis and evaluation of indazole based analog sensitive Akt inhibitors", Molecular Biosystems, (20100628), vol. 6, no. 8, pages 1389 - 1402, XP055543009 [X] 1, 2, 4, 6-8, 14, 16, 18, 27 * Compound Xli. *

DOI:   http://dx.doi.org/10.1039/c003917a
 [Y]  - LOURIDO S et al., "Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii", Journal of medicinal chemistry, (20130326), vol. 56, no. 7, pages 3068 - 3077, XP055479238 [Y] 1-37 * Whole document. *

DOI:   http://dx.doi.org/10.1021/jm4001314
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