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Extract from the Register of European Patents

EP About this file: EP3612828

EP3612828 - METHODS AND KITS FOR EVALUATING ZINC LEVELS IN MILK [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  29.10.2021
Database last updated on 07.10.2024
FormerRequest for examination was made
Status updated on  24.01.2020
FormerThe international publication has been made
Status updated on  20.10.2018
Most recent event   Tooltip29.10.2021Application deemed to be withdrawnpublished on 01.12.2021  [2021/48]
Applicant(s)For all designated states
Technion Research & Development Foundation Ltd.
Senate House
Technion City
3200004 Haifa / IL
[2020/09]
Inventor(s)01 / ASSARAF, Yehuda G.
D.N. Misgav
2017500 Rakefet / IL
02 / GOLAN MAOR, Yarden
Moshav Merchavia
1910500 Moshav Merchavia / IL
 [2020/09]
Representative(s)Boult Wade Tennant LLP
Salisbury Square House
8 Salisbury Square
London EC4Y 8AP / GB
[2020/09]
Application number, filing date18785030.011.04.2018
[2020/09]
WO2018IL50416
Priority number, dateUS201762484365P11.04.2017         Original published format: US 201762484365 P
[2020/09]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018189743
Date:18.10.2018
Language:EN
[2018/42]
Type: A1 Application with search report 
No.:EP3612828
Date:26.02.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 18.10.2018 takes the place of the publication of the European patent application.
[2020/09]
Search report(s)International search report - published on:IL18.10.2018
(Supplementary) European search report - dispatched on:EP26.11.2020
ClassificationIPC:G01N29/02, C12Q1/68, G01N33/48, C12Q1/6883
[2021/01]
CPC:
C12Q1/6883 (EP,US); G01N33/487 (US); C12Q2600/156 (EP,US)
Former IPC [2020/09]G01N29/02, C12Q1/68, G01N33/48
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/09]
TitleGerman:VERFAHREN UND KITS ZUR BEURTEILUNG DES ZINKGEHALTS IN MILCH[2020/09]
English:METHODS AND KITS FOR EVALUATING ZINC LEVELS IN MILK[2020/09]
French:PROCÉDÉS ET KITS DESTINÉS À ÉVALUER LES NIVEAUX DE ZINC DANS LE LAIT[2020/09]
Entry into regional phase11.11.2019National basic fee paid 
11.11.2019Search fee paid 
11.11.2019Designation fee(s) paid 
11.11.2019Examination fee paid 
Examination procedure11.11.2019Amendment by applicant (claims and/or description)
11.11.2019Examination requested  [2020/09]
26.06.2021Application deemed to be withdrawn, date of legal effect  [2021/48]
16.07.2021Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2021/48]
Fees paidRenewal fee
27.04.2020Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
30.04.202104   M06   Not yet paid
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Documents cited:Search[X]US2005106675  (WEI MING-HUI [US], et al) [X] 13* 0002], [0150] and [0153] *;
 [XI]  - LINXI QIAN ET AL, "Polymorphisms of SLC30A2 and selected perinatal factors associated with low milk zinc in Chinese breastfeeding women", EARLY HUMAN DEVELOPMENT, SHANNON, IR, vol. 88, no. 8, doi:10.1016/J.EARLHUMDEV.2012.01.011, ISSN 0378-3782, (20120127), pages 663 - 668, (20120204), XP028401252 [X] 1-6,9 * abstract, tab. 1 and p. 667 col. 2 * [I] 7,8,10-12,14,15

DOI:   http://dx.doi.org/10.1016/j.earlhumdev.2012.01.011
 [XI]  - NAOYA ITSUMURA ET AL, "Novel mutations in SLC30A2 involved in the pathogenesis of transient neonatal zinc deficiency", PEDIATRIC RESEARCH, US, (20160615), vol. 80, no. 4, doi:10.1038/pr.2016.108, ISSN 0031-3998, pages 586 - 594, XP055552981 [X] 1-6,9 * abstract, Fig. 1 and p. 587 col. 1-2 * [I] 7,8,10-12,14,15

DOI:   http://dx.doi.org/10.1038/pr.2016.108
 [XI]  - YARDEN GOLAN ET AL, "Molecular Basis of Transient Neonatal Zinc Deficiency : NOVEL ZnT2 MUTATIONS DISRUPTING ZINC BINDING AND PERMEATION", JOURNAL OF BIOLOGICAL CHEMISTRY, US, (20160502), vol. 291, no. 26, doi:10.1074/jbc.M116.732693, ISSN 0021-9258, pages 13546 - 13559, XP055552985 [X] 1-6,9 * abstract and Tab. 1 * [I] 7,8,10-12,14,15

DOI:   http://dx.doi.org/10.1074/jbc.M116.732693
International search[YA]  - ITSUMURA, NAOYA et al., "Novel mutations in SLC30A2 involved in the pathogenesis of transient neonatal zinc deficiency", Pediatric research, vol. 80, no. 4, (20160615), pages 586 - 594, URL: doi:10.1038/pr.2016.108, XP055552981 [Y] 1-7, 10-27 * the whole document the whole document * [A] 8, 9

DOI:   http://dx.doi.org/10.1038/pr.2016.108
 [YA]  - GOLAN, YARDEN et al., "Molecular basis of transient neonatal zinc deficiency novel ZnT2 mutations disrupting zinc binding and permeation", Journal of Biological Chemistry, vol. 291, no. 26, (20160502), pages 13546 - 13559, URL: doi: 10.1074/jbc.M116.732693, XP055552985 [Y] 1, 6 * the whole document the whole document * [A] 2-5, 7-27

DOI:   http://dx.doi.org/10.1074/jbc.M116.732693
 [Y]  - ITSUMURA, NAOYA et al., "Compound heterozygous mutations in SLC30A2/ZnT2 results in low milk zinc concentrations: a novel mechanism for zinc deficiency in a breast-fed infant", PloS one, vol. 8, no. 5, (20130531), page 1-11, URL: https://doi.org/10.1371/journal.pone.0064045, XP055552987 [Y] 1, 6, 7 * the whole document the whole document *

DOI:   http://dx.doi.org/10.1371/journal.pone.0064045
 [YA]  - LOVA NAVARRO, MIGUEL et al., "Transient neonatal zinc deficiency due to a New autosomal dominant mutation in gene SLC30A2 (ZnT?2)", Pediatric dermatology, vol. 31, no. 2, (20140123), pages 251 - 252, URL: doi:10.1111/pde.12257, XP055552988 [Y] 1, 7 * the whole document the whole document * [A] 2-6,8-27

DOI:   http://dx.doi.org/10.1111/pde.12257
 [YA]  - LEMAY, DANIELLE G. et al., "Sequencing the transcriptome of milk production: milk trumps mammary tissue", BMC genomics, vol. 14.1, (20131212), page 872, URL: DOI:10.1186/1471-2164-14-872, XP021170682 [Y] 1-7, 10-27 * the whole document the whole document * [A] 8, 9

DOI:   http://dx.doi.org/10.1186/1471-2164-14-872
 [YA]  - CHOWANADISAI, WINYOO et al., "Identification of a mutation in SLC30A2 (ZnT-2) in women with low milk zinc concentration that results in transient neonatal zinc deficiency", Journal of Biological Chemistry, vol. 281, no. 51, (20061025), pages 39699 - 39707, URL: DOI: 10.1074/jbc.M605821200, XP055552989 [Y] 1, 7 * the whole document the whole document * [A] 2-6, 8-27

DOI:   http://dx.doi.org/10.1074/jbc.M605821200
 [YA]  - LASRY, INBAL et al., "A dominant negative heterozygous G87R mutation in the zinc transporter, ZnT-2 (SLC30A2) results in transient neonatal zinc deficiency", Journal of Biological Chemistry, vol. 287, no. 35, (20120625), pages 29348 - 29361, URL: doi:10.1074/jbc.M112.368159, XP055552990 [Y] 1, 7 * the whole document the whole document * [A] 2-6, 8-27

DOI:   http://dx.doi.org/10.1074/jbc.M112.368159
 [PX]  - GOLAN, YARDEN et al., "Identification of Genetic Diseases Using Breast Milk Cell Analysis: The Case of Transient Neonatal Zinc Deficiency (TNZD", Cellular & Molecular Medicine: Open access, vol. 3, no. 2, (20170523), pages 1 - 12, URL: DOI:10.21767/2573-5365.100031, XP055552993 [PX] 1-27 * the whole document *

DOI:   http://dx.doi.org/10.21767/2573-5365.100031
 [A]  - "Homo sapiens solute carrier family 30 member 2 (SLC30A2), transcript variant 1 , mRNA", GeneBank, (19960415), Database accession no. NM_001004434.2 [A] 4-27
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.