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Extract from the Register of European Patents

EP About this file: EP3654979

EP3654979 - USE OF WX-UK1 AND ITS PRODRUG, WX-671, FOR THE TREATMENT OF NON-CANCEROUS MEDICAL CONDITIONS [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  30.09.2022
Database last updated on 19.07.2024
FormerRequest for examination was made
Status updated on  24.04.2020
FormerThe international publication has been made
Status updated on  26.01.2019
Most recent event   Tooltip30.09.2022Withdrawal of applicationpublished on 02.11.2022  [2022/44]
Applicant(s)For all designated states
Redhill Biopharma Ltd.
21 Ha'arba's Street
Tel-Aviv / IL
[2020/22]
Inventor(s)01 / FATHI, Reza
260 Forest Avenue
Oradell NJ 07649 / US
02 / LEVITT, Mark
18/1 Hatavor Street
73127 Haashmonaim / IL
03 / PLASSE, Terry
1725 York Avenue
New York NY 10128 / US
04 / ABRAMSON, Danielle
18a Forest Place
Towaco NJ 07082 / US
 [2020/22]
Representative(s)CMS Cameron McKenna Nabarro Olswang LLP
Cannon Place
78 Cannon Street
London EC4N 6AF / GB
[2020/22]
Application number, filing date18835233.013.07.2018
[2020/22]
WO2018IB00881
Priority number, dateUS201762535376P21.07.2017         Original published format: US 201762535376 P
US201762574449P19.10.2017         Original published format: US 201762574449 P
US201762589734P22.11.2017         Original published format: US 201762589734 P
[2020/22]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019016595
Date:24.01.2019
Language:EN
[2019/04]
Type: A1 Application with search report 
No.:EP3654979
Date:27.05.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 24.01.2019 takes the place of the publication of the European patent application.
[2020/22]
Search report(s)International search report - published on:US24.01.2019
(Supplementary) European search report - dispatched on:EP15.03.2021
ClassificationIPC:A61K31/495, C07D295/00, G01N33/68, A61P1/04, A61P1/18, G01N33/573
[2021/15]
CPC:
A61K31/495 (EP,KR,US); A61K9/0053 (KR); A61P1/04 (EP,KR);
A61P1/18 (EP,KR); A61P29/00 (KR); G01N33/573 (EP,US);
G01N33/6893 (KR); G01N2333/96433 (EP,US); G01N2333/976 (KR);
G01N2800/52 (EP,KR,US) (-)
Former IPC [2020/22]A61K31/4965, C07D295/00, G01N33/68
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/22]
TitleGerman:VERWENDUNG VON WX-UK1 UND SEINEM PRODRUG, WX-671, ZUR BEHANDLUNG VON NICHTKREBSARTIGEN ERKRANKUNGEN[2020/22]
English:USE OF WX-UK1 AND ITS PRODRUG, WX-671, FOR THE TREATMENT OF NON-CANCEROUS MEDICAL CONDITIONS[2020/22]
French:UTILISATION DE WX-UK1 ET DE SON PROMÉDICAMENT, WX-671, POUR LE TRAITEMENT D'AFFECTIONS MÉDICALES NON CANCÉREUSES[2020/22]
Entry into regional phase10.02.2020National basic fee paid 
10.02.2020Search fee paid 
10.02.2020Designation fee(s) paid 
10.02.2020Examination fee paid 
Examination procedure10.02.2020Examination requested  [2020/22]
01.10.2021Amendment by applicant (claims and/or description)
26.09.2022Application withdrawn by applicant  [2022/44]
Fees paidRenewal fee
14.07.2020Renewal fee patent year 03
15.07.2021Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
31.07.202205   M06   Not yet paid
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Documents cited:Search[Y]US5534498  (BRUNCK TERENCE K [US], et al) [Y] 1-15 * col. 10, l. 7-11 *;
 [Y]US2004138233  (WILHELM OLAF [DE], et al) [Y] 1-15 * paragraph [0119] *;
 [XP]  - Oldenberg Emil ET AL, "New potential therapeutic applications of WX-UK1 as a specific and potent inhibitor of human trypsin-2 and human trypsin-3", New Molecular Targets, doi:10.1158/1535-7163.TARG-17-B055Published, (20180101), URL: https://mct.aacrjournals.org/content/17/1_Supplement/B055, (20210302), XP055781163 [XP] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1158/1535-7163.TARG-17-B055Published
International search[Y]US7608623  (SPERL STEFAN [DE], et al) [Y] 1-20 * Col. 5, In 1-4; Col 5, In 35-40; Col 5, In 51-57;Col 6, In 1-6;Col 12, In 47-52; Col 16, In 21 *;
 [Y]US2014199709  (GONG HUA [US], et al) [Y] 1-20 * (para [0010]; [0042]; [0068][0252];[0385];[0389] *;
 [Y]  - FOURCADE et al., "Epithelial Expression and Function of Trypsin-3 in Irritable Bowel Syndrome", Gut, vol. 66, (20170000), pages 1767 - 1778, (20170117), XP055573669 [Y] 17, 18, 20 * abstract; pg. 1768, Col 1, para 1; pg. 1773, Figure 2 *

DOI:   http://dx.doi.org/10.1136/gutjnl-2016-312094
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.