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Extract from the Register of European Patents

EP About this file: EP3681532

EP3681532 - PROTEINS BINDING NKG2D, CD16, AND C-TYPE LECTIN-LIKE MOLECULE-1 (CLL-1) [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  19.06.2020
Database last updated on 14.06.2024
FormerThe international publication has been made
Status updated on  22.03.2019
Most recent event   Tooltip27.04.2024Change - applicantpublished on 29.05.2024  [2024/22]
Applicant(s)For all designated states
Dragonfly Therapeutics, Inc.
180 3rd Avenue, Sixth Floor
Waltham, MA 02451 / US
[2024/22]
Former [2020/30]For all designated states
Dragonfly Therapeutics, Inc.
35 Gatehouse Drive
Waltham, MA 02451 / US
Inventor(s)01 / CHANG, Gregory, P.
143 Saunders Street
Medford MA 02155 / US
02 / CHEUNG, Ann, F.
25 Morningside Lane
Lincoln MA 01773 / US
03 / HANEY, William
61 Lincoln Road
Wayland MA 01778 / US
04 / LUNDE, Bradley, M.
7 Lucent Drive
Lebanon NH 03766 / US
05 / PRINZ, Bianka
7 Lucent Drive
Lebanon NH 03766 / US
 [2020/30]
Representative(s)Redhouse, Juliet Lauren
Mathys & Squire The Shard
32 London Bridge Street
London SE1 9SG / GB
[N/P]
Former [2020/30]Haseltine Lake Kempner LLP
Lincoln House, 5th Floor
300 High Holborn
London WC1V 7JH / GB
Application number, filing date18856132.813.09.2018
[2020/30]
WO2018US50916
Priority number, dateUS201762558510P14.09.2017         Original published format: US 201762558510 P
[2020/30]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019055677
Date:21.03.2019
Language:EN
[2019/12]
Type: A1 Application with search report 
No.:EP3681532
Date:22.07.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 21.03.2019 takes the place of the publication of the European patent application.
[2020/30]
Search report(s)International search report - published on:US21.03.2019
(Supplementary) European search report - dispatched on:EP03.08.2021
ClassificationIPC:C07K16/28, C07K16/46
[2021/35]
CPC:
A61P35/00 (EP,EA,KR,US); C07K16/2851 (EP,EA,KR,US); A61K39/395 (EA);
C07K16/283 (EP,EA,KR,US); A61K2039/505 (EP,EA,KR,US); C07K2317/31 (US);
C07K2317/33 (EP,EA,KR,US); C07K2317/524 (US); C07K2317/565 (US);
C07K2317/569 (US); C07K2317/73 (US); C07K2317/75 (EP,EA,KR,US);
C07K2317/94 (EP,EA,KR,US) (-)
Former IPC [2020/30]A61K39/00, A61K39/395, A61P35/00, C07K16/28, C07K16/46
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/30]
Extension statesBA15.06.2020
ME15.06.2020
Validation statesKH15.06.2020
MA15.06.2020
MD15.06.2020
TN15.06.2020
TitleGerman:NKG2D, CD1 6 UND C-TYP-LECTIN-LIKE-MOLEKÜL 1 (CLL-1) BINDENDE PROTEINE[2020/30]
English:PROTEINS BINDING NKG2D, CD16, AND C-TYPE LECTIN-LIKE MOLECULE-1 (CLL-1)[2020/30]
French:PROTÉINES DE LIAISON À NKG2D, CD16, ET MOLÉCULE-1 SEMBLABLE À LA LECTINE DE TYPE C (CLL-1)[2020/30]
Entry into regional phase20.03.2020National basic fee paid 
20.03.2020Search fee paid 
20.03.2020Designation fee(s) paid 
20.03.2020Examination fee paid 
Examination procedure20.03.2020Examination requested  [2020/30]
28.02.2022Amendment by applicant (claims and/or description)
Fees paidRenewal fee
28.09.2020Renewal fee patent year 03
15.09.2021Renewal fee patent year 04
11.08.2022Renewal fee patent year 05
24.08.2023Renewal fee patent year 06
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Documents cited:Search[I]WO2007002905  (UNIV MIAMI [US], et al) [I] 1-16 * paragraphs [0012] , [0013] , [0060] , [0061] , [0065] , [0066] *;
 [A]WO2009007124  (FRIEDRICH ALEXANDER UNI [DE], et al) [A] 1-16;
 [A]  - MAELIG G. MORVAN ET AL, "NK cells and cancer: you can teach innate cells new tricks", NATURE REVIEWS CANCER, London, (20160101), vol. 16, no. 1, doi:10.1038/nrc.2015.5, ISSN 1474-175X, pages 7 - 19, XP055484885 [A] 1-16

DOI:   http://dx.doi.org/10.1038/nrc.2015.5
 [A]  - GERMAIN CLAIRE ET AL, "MHC Class I-Related Chain a Conjugated to Antitumor antibodies Can Sensitize Tumor Cells to Specific Lysis by Natural Killer Cell", CLINICAL CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, (20051015), vol. 11, no. 20, doi:10.1158/1078-0432.CCR-05-0872, ISSN 1078-0432, pages 7516 - 7522, XP008084621 [A] 1-16

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-05-0872
 [A]  - CHRISTIAN KELLNER ET AL, "Promoting natural killer cell functions by recombinant immunoligands mimicking an induced self phenotype", ONCOIMMUNOLOGY, US, (20130627), vol. 2, no. 6, doi:10.4161/onci.24481, ISSN 2162-4011, page e24481, XP055684159 [A] 1-16

DOI:   http://dx.doi.org/10.4161/onci.24481
 [A]  - HARUKO TASHIRO ET AL, "Treatment of Acute Myeloid Leukemia with T Cells Expressing Chimeric Antigen Receptors Directed to C-type Lectin-like Molecule 1", MOLECULAR THERAPY, US, (20170901), vol. 25, no. 9, doi:10.1016/j.ymthe.2017.05.024, ISSN 1525-0016, pages 2202 - 2213, XP055579188 [A] 1-16

DOI:   http://dx.doi.org/10.1016/j.ymthe.2017.05.024
 [A]  - X. ZHAO ET AL, "Targeting C-type lectin-like molecule-1 for antibody-mediated immunotherapy in acute myeloid leukemia", HAEMATOLOGICA, (20090731), vol. 95, no. 1, doi:10.3324/haematol.2009.009811, ISSN 0390-6078, pages 71 - 78, XP055094666 [A] 1-16

DOI:   http://dx.doi.org/10.3324/haematol.2009.009811
 [A]  - ANNA VAN RHENEN ET AL, "The novel AML stem cell associated antigen CLL-1 aids in discrimination between normal and leukemic stem cells", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 110, no. 7, doi:10.1182/BLOOD-2007-03-083048, ISSN 0006-4971, (20071001), pages 2659 - 2666, (20070703), XP002632479 [A] 1-16

DOI:   http://dx.doi.org/10.1182/BLOOD-2007-03-083048
 [AP]  - EDUARDO LABORDA ET AL, "Development of A Chimeric Antigen Receptor Targeting C-Type Lectin-Like Molecule-1 for Human Acute Myeloid Leukemia", INT. J. MOL. SCI., (20171101), vol. 18, no. 11, doi:10.3390/ijms18112259, ISSN 1661-6596, page 2259, XP055690425 [AP] 1-16

DOI:   http://dx.doi.org/10.3390/ijms18112259
International search[A]US2010056764  (URSOE BIRGITTE [DK], et al) [A] 1-4, 20, 21* entire document *;
 [A]US2011311535  (DRANOFF GLENN [US], et al) [A] 1-4, 20, 21 * entire document *;
 [X]WO2017125897  (NOVARTIS AG [CH]) [X] 1-4, 20, 21 * entire document *;
 [PX]WO2018157147  (DRAGONFLY THERAPEUTICS INC [US]) [PX] 1-4, 20, 21 * entire document *
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