EP3668997 - MiRNA DETARGETING SYSTEM FOR TISSUE SPECIFIC INTERFERENCE [Right-click to bookmark this link] | Status | Examination is in progress Status updated on 03.11.2023 Database last updated on 03.09.2024 | |
Former | Request for examination was made Status updated on 22.05.2020 | ||
Former | The international publication has been made Status updated on 13.04.2019 | Most recent event Tooltip | 06.05.2024 | New entry: Reply to examination report | Applicant(s) | For all designated states Research Institute at Nationwide Children's Hospital 700 Children's Drive, Room W172 Columbus, Ohio 43205 / US | [2020/26] | Inventor(s) | 01 /
HARPER, Scott, Quenton 384 Briarbend Boulevard Powell, OH 43065 / US | [2020/26] | Representative(s) | Forresters IP LLP Skygarden Erika-Mann-Straße 11 80636 München / DE | [N/P] |
Former [2020/26] | Walker, Ross Thomson Forresters IP LLP Skygarden Erika-Mann-Strasse 11 80636 München / DE | Application number, filing date | 18863924.9 | 02.10.2018 | [2020/26] | WO2018US54005 | Priority number, date | US201762566966P | 02.10.2017 Original published format: US 201762566966 P | [2020/26] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2019070741 | Date: | 11.04.2019 | Language: | EN | [2019/15] | Type: | A1 Application with search report | No.: | EP3668997 | Date: | 24.06.2020 | Language: | EN | The application published by WIPO in one of the EPO official languages on 11.04.2019 takes the place of the publication of the European patent application. | [2020/26] | Search report(s) | International search report - published on: | US | 11.04.2019 | (Supplementary) European search report - dispatched on: | EP | 15.04.2021 | Classification | IPC: | C12N15/11, C12N15/113, A61K31/7088, A61P21/00 | [2021/20] | CPC: |
C12N15/63 (EP);
C12N15/113 (EP,US);
A61K35/76 (US);
C12N15/111 (EP);
C12N15/86 (US);
C12N7/00 (US);
A61K48/00 (US);
C12N2310/141 (EP);
C12N2330/51 (EP);
|
Former IPC [2020/26] | C12Q1/68, C07H21/02 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2020/26] | Extension states | BA | 20.03.2020 | ME | 20.03.2020 | Validation states | KH | 20.03.2020 | MA | 20.03.2020 | MD | 20.03.2020 | TN | 20.03.2020 | Title | German: | SYSTEM ZUM MIRNA-DETARGETING FÜR GEWEBESPEZIFISCHE INTERFERENZ | [2020/26] | English: | MiRNA DETARGETING SYSTEM FOR TISSUE SPECIFIC INTERFERENCE | [2020/26] | French: | SYSTÈME DE DÉCIBLAGE DE MIARN POUR INTERFÉRENCE SPÉCIFIQUE D'UN TISSU | [2020/26] | Entry into regional phase | 20.03.2020 | National basic fee paid | 20.03.2020 | Search fee paid | 20.03.2020 | Designation fee(s) paid | 20.03.2020 | Examination fee paid | Examination procedure | 20.03.2020 | Examination requested [2020/26] | 15.11.2021 | Amendment by applicant (claims and/or description) | 03.11.2023 | Despatch of a communication from the examining division (Time limit: M06) | 03.05.2024 | Reply to a communication from the examining division | Fees paid | Renewal fee | 14.10.2020 | Renewal fee patent year 03 | 29.09.2021 | Renewal fee patent year 04 | 15.09.2022 | Renewal fee patent year 05 | 13.09.2023 | Renewal fee patent year 06 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [X]US2010186103 (GAO GUANGPING [US], et al) [X] 1,3,7-11,14,15 * claims 1-6,18 *; | [XYI]WO2010138263 (UNIV MASSACHUSETTS [US], et al) [X] 1-3,7-11,14,15 * page 24; claims 29-39 * [Y] 4,12,13 [I] 5,6; | [XYI]WO2011133890 (UNIV MASSACHUSETTS [US], et al) [X] 1,3,7-11,14,15 * page 7; examples 1,3,8; claims 1,11,12,30; sequence 21 * [Y] 4,12,13 [I] 2,5,6; | [A]WO2013016352 (NATIONWIDE CHILDREN S HOSPITAL INC [US], et al) [A] 1-15* claims 1-10 *; | [XP]WO2017173411 (RES INST AT NATION WIDE CHILDREN'S HOSPITAL [US]) [XP] 1-15 * claims 1-16,21,22; sequence 3 *; | [Y] - A GEISLER ET AL, "microRNA122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors", GENE THERAPY, (20101104), vol. 18, no. 2, doi:10.1038/gt.2010.141, ISSN 0969-7128, pages 199 - 209, XP055078590 [Y] 1-15 * figures 2,6 * DOI: http://dx.doi.org/10.1038/gt.2010.141 | [Y] - ZHOU H ET AL, "A tightly regulated Pol III promoter for synthesis of miRNA genes in tandem", BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS, ELSEVIER, AMSTERDAM, NL, vol. 1779, no. 11, doi:10.1016/J.BBAGRM.2008.03.011, ISSN 1874-9399, (20080407), pages 773 - 779, (20080407), XP025678681 [Y] 1-15 * figures 2,3 * DOI: http://dx.doi.org/10.1016/j.bbagrm.2008.03.011 | [A] - RAVIKANTH DANDA ET AL, "Targeted Expression of Suicide Gene by Tissue-Specific Promoter and MicroRNA Regulation for Cancer Gene Therapy", PLOS ONE, (20131231), vol. 8, no. 12, doi:10.1371/journal.pone.0083398, page e83398, XP055320669 [A] 1-15 * figure 4 * DOI: http://dx.doi.org/10.1371/journal.pone.0083398 | [A] - WOLFF LISA J ET AL, "Effect of tissue-specific promoters and microRNA recognition elements on stability of transgene expression after hydrodynamic naked plasmid DNA delivery", HUMAN GENE THERAPY, GB, vol. 20, no. 4, doi:10.1089/hum.2008.088, ISSN 1043-0342, (20090312), pages 374 - 388, URL: https://www.liebertpub.com/doi/pdfplus/10.1089/hum.2008.088, XP055792052 [A] 1-15 * figure 1 * DOI: http://dx.doi.org/10.1089/hum.2008.088 | International search | [Y]US2013195801 (GAO GUANGPING [US], et al) [Y] 1-3 * Abstract; para [0007]; para [0012] *; | [Y]US2017166925 (GAO GUANGPING [US], et al) [Y] 1-3 * Claim 1; para [0029]; para [0030]; para [0040]; para [0099] *; | [Y] - MCMANUS et al., "Gene silencing using micro-RNA designed hairpins", RNA, (20020600), vol. 8, no. 6, doi:doi:10.1017/S1355838202024032, pages 842 - 850, XP008021481 [Y] 1-3 * . Especially Abstract, page 847, col 2, last para * DOI: http://dx.doi.org/10.1017/S1355838202024032 |