blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
FAQ - Register Alert
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP3608330

EP3608330 - SYNTHETIC INTERMEDIATES FOR PREPARING OLIGOSACCHARIDE-PROTEIN CONJUGATES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  15.09.2023
Database last updated on 15.06.2024
FormerThe patent has been granted
Status updated on  07.10.2022
FormerGrant of patent is intended
Status updated on  18.05.2022
FormerExamination is in progress
Status updated on  04.06.2021
FormerRequest for examination was made
Status updated on  13.11.2020
FormerThe application has been published
Status updated on  10.01.2020
Most recent event   Tooltip14.06.2024Lapse of the patent in a contracting state
New state(s): TR		published on 17.07.2024 [2024/29]
Applicant(s)For all designated states
Genzyme Corporation
50 Binney Street
Cambridge, MA 02142 / US
[2020/07]
Inventor(s)01 / PAN, Clark Q.
353 Dutton Road
Sudbury, MA 01766 / US
02 / ZHENG, Xiaoyang
18 Murray Terrace
Newton, MA 02465 / US
03 / MILLER, Robert J.
120 Northridge Drive
East Bridgewater, MA 02333 / US
04 / KUTZKO, Joseph P.
15 Newton Street
Southborough, MA 01772 / US
05 / ZHU, Yunxiang
10 Caulfield Road
Wayland, MA 01778 / US
06 / PATTERSON, Duncan E.
Ruedi-Walter-Strasse 2A
8050 Zurich / CH
07 / PEER, Andreas
Anergis A
Biopole III
Route de la Corniche 9B
1066 Epalinges / CH
08 / KONOWICZ, Paul A.
35 Thoreau Circle
Beverly, MA 01915 / US
09 / AVILA, Luis Z.
11 Sleepy Hollow Lane
Arlington, MA 02474 / US
10 / STEFANO, James E.
199 Saddlehill Road
Hopkinton, MA 01701 / US
11 / REARDON, Michael R.
77 Arnold Road
North Attleboro, MA 02760 / US
12 / HARRAHY, John
8 Autumn Road
Medway, MA 02053 / US
13 / ZHOU, Qun
15 Harris Lane
Ashland, MA 01721 / US
14 / YOUNG, Lauren
210 Landing Road
Hampton, NH 03842 / US
15 / FINN, Patrick
909 Pleasant Street Unit 16
Weymouth, MA 02183 / US
 [2020/07]
Representative(s)Mathys & Squire
The Shard
32 London Bridge Street
London SE1 9SG / GB
[2022/45]
Former [2020/07]Rai, Monika, et al
Mathys & Squire LLP The Shard
32 London Bridge Street
London SE1 9SG / GB
Application number, filing date19167964.611.12.2009
[2020/07]
Priority number, dateUS200812285108P16.12.2008         Original published format: US 12285108 P
[2020/07]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP3608330
Date:12.02.2020
Language:EN
[2020/07]
Type: A3 Search report 
No.:EP3608330
Date:13.05.2020
Language:EN
[2020/20]
Type: B1 Patent specification 
No.:EP3608330
Date:09.11.2022
Language:EN
[2022/45]
Search report(s)(Supplementary) European search report - dispatched on:EP14.04.2020
ClassificationIPC:C07H15/04, A61P3/00, A61K47/61
[2020/07]
CPC:
C07H15/04 (EP,BR,IL,US); A61K38/46 (CN,IL,US); A61K47/61 (EP,BR,IL,US);
A61P3/00 (EP,IL); A61P43/00 (EP,IL)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2020/51]
Former [2020/07]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  SM,  TR 
TitleGerman:SYNTHETISCHE ZWISCHENPRODUKTE ZUR VERWENDUNG ZUR HERSTELLUNG VON OLIGOSACCHARID-PROTEIN-KONJUGATE[2020/07]
English:SYNTHETIC INTERMEDIATES FOR PREPARING OLIGOSACCHARIDE-PROTEIN CONJUGATES[2020/07]
French:INTERMÉDIAIRES SYNTHÉTIQUES UTILES DANS LA PRÉPARATION DES CONJUGUÉS OLIOGOSACCHARIDE-PROTÉINE[2020/07]
Examination procedure11.11.2020Examination requested  [2020/51]
11.11.2020Date on which the examining division has become responsible
03.12.2020Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
11.02.2021Amendment by applicant (claims and/or description)
04.06.2021Despatch of a communication from the examining division (Time limit: M06)
14.12.2021Reply to a communication from the examining division
19.05.2022Communication of intention to grant the patent
27.09.2022Fee for grant paid
27.09.2022Fee for publishing/printing paid
27.09.2022Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP09771640.1  / EP2376123
EP12160009.2  / EP2465542
EP14194176.5  / EP2889043
Divisional application(s)EP22205652.5  / EP4212541
Opposition(s)10.08.2023No opposition filed within time limit [2023/42]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
11.02.2021Request for further processing filed
11.02.2021Full payment received (date of receipt of payment)
Request granted
18.02.2021Decision despatched
Fees paidRenewal fee
05.08.2019Renewal fee patent year 03
05.08.2019Renewal fee patent year 04
05.08.2019Renewal fee patent year 05
05.08.2019Renewal fee patent year 06
05.08.2019Renewal fee patent year 07
05.08.2019Renewal fee patent year 08
05.08.2019Renewal fee patent year 09
05.08.2019Renewal fee patent year 10
13.12.2019Renewal fee patent year 11
14.12.2020Renewal fee patent year 12
30.11.2021Renewal fee patent year 13
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipEE09.11.2022
FI09.11.2022
HR09.11.2022
LT09.11.2022
LV09.11.2022
MK09.11.2022
PL09.11.2022
RO09.11.2022
SI09.11.2022
SK09.11.2022
SM09.11.2022
TR09.11.2022
LU11.12.2022
GR10.02.2023
IS09.03.2023
PT09.03.2023
[2024/29]
Former [2024/27]EE09.11.2022
FI09.11.2022
HR09.11.2022
LT09.11.2022
LV09.11.2022
MK09.11.2022
PL09.11.2022
RO09.11.2022
SI09.11.2022
SK09.11.2022
SM09.11.2022
LU11.12.2022
GR10.02.2023
IS09.03.2023
PT09.03.2023
Former [2023/51]EE09.11.2022
FI09.11.2022
HR09.11.2022
LT09.11.2022
LV09.11.2022
PL09.11.2022
RO09.11.2022
SI09.11.2022
SK09.11.2022
SM09.11.2022
LU11.12.2022
GR10.02.2023
IS09.03.2023
PT09.03.2023
Former [2023/38]EE09.11.2022
FI09.11.2022
HR09.11.2022
LT09.11.2022
LV09.11.2022
PL09.11.2022
RO09.11.2022
SK09.11.2022
SM09.11.2022
LU11.12.2022
GR10.02.2023
IS09.03.2023
PT09.03.2023
Former [2023/35]EE09.11.2022
FI09.11.2022
HR09.11.2022
LT09.11.2022
LV09.11.2022
PL09.11.2022
RO09.11.2022
SM09.11.2022
GR10.02.2023
IS09.03.2023
PT09.03.2023
Former [2023/34]EE09.11.2022
FI09.11.2022
HR09.11.2022
LT09.11.2022
LV09.11.2022
PL09.11.2022
SM09.11.2022
GR10.02.2023
IS09.03.2023
PT09.03.2023
Former [2023/33]FI09.11.2022
HR09.11.2022
LT09.11.2022
LV09.11.2022
PL09.11.2022
SM09.11.2022
GR10.02.2023
IS09.03.2023
PT09.03.2023
Former [2023/25]FI09.11.2022
HR09.11.2022
LT09.11.2022
LV09.11.2022
PL09.11.2022
GR10.02.2023
IS09.03.2023
PT09.03.2023
Former [2023/23]FI09.11.2022
LT09.11.2022
LV09.11.2022
GR10.02.2023
PT09.03.2023
Former [2023/22]FI09.11.2022
LT09.11.2022
PT09.03.2023
Former [2023/20]LT09.11.2022
Documents cited:Search[A]US2005058634  (ZHU YUNXIANG [US]) [A] 1-8 * paragraph [0086] *;
 [A]WO2008089403  (GENZYME CORP [US], et al) [A] 1-8 * paragraph [0106]; figure 1; claim 2; compounds 1-3 *;
 [A]  - SUGAWARA T ET AL, "SYNTHESIS OF OMEGA-(METHOXYCARBONYL)ALKYL AND 9-(METHOXYCARBONYL)-3,6-DIOXANONYL GLYCOPYRANOSIDES FOR THE PREPARATION OF CARBOHYDRATE-PROTEIN CONJUGATES", CARBOHYDRATE RESEARCH, PERGAMON, GB, (19920101), vol. 230, no. 1, doi:10.1016/S0008-6215(00)90517-2, ISSN 0008-6215, pages 117 - 150, XP001018683 [A] 1-8 * page 123, last paragraph; page 118, paragraph 3; compound 15 *

DOI:   http://dx.doi.org/10.1016/S0008-6215(00)90517-2
 [A]  - SLODKI ET AL, "Phosphate linkages in phosphomannans from yeast", BIOCHIMICA ET BIOPHYSICA ACTA, ELSEVIER, NL, vol. 57, no. 1, ISSN 0006-3002, (19620101), pages 525 - 533, (19620101), XP027177746 [A] 1-8 * page 526, paragraph 1 *
by applicantUS4671958
 US4867973
 US5153312
 US5212298
 US5280113
 US5306492
 US5324663
 US5521290
 US5691154
 US5846728
 US5952516
 US6066626
 US6071890
 US6156547
 US6287857
 US6472506
 US2003050299
 US6534300
 US6541669
 US2003087868
 US6573337
 US2003153768
 US6670165
 US6723843
 US6861242
 US6905856
 US2005222244
 US2005267094
 US7001994
 US7019131
 US2006228348
 US7141676
 US7160517
 US7176185
 US7232805
 WO2008089403
    - GAA. ZHU et al., Biochem. J., (20050000), vol. 389, pages 619 - 628
    - J. Biol. Chem., (19910000), vol. 266, pages 21687 - 21692
    - BALAJI et al., Glycobiology, (19940000), vol. 4, pages 497 - 515
    - OLSON et al., J. Biol. Chem., (20040000), vol. 279, pages 34000 - 34009
    - OLSON et al., EMBO J., (20040000), vol. 23, pages 2019 - 2028
    - OLSON et al., J. Biol. Chem., (19990000), vol. 274, pages 29889 - 29886
    - OLSON et al., J. Biol. Chem., (20020000), vol. 277, pages 10156 - 10161
    - DUFFELS et al., Chem, Eur. J., (20000000), vol. 6, pages 1416 - 1430
    - HOJO et al., Current Prot. Peptide Sci., (20000000), vol. 1, pages 23 - 48
    - SEEBERGER, Nature, (20070000), vol. 446, pages 1046 - 1051
    - SEEBERGER et al., Nature Rev. Drug Discov., (20050000), vol. 4, pages 751 - 763
    - SRIVASTANA et al., Carbohydrate Res., (19870000), vol. 161, pages 195 - 210
    - HAGIHARA et al., Chem. Rec., (20060000), vol. 6, pages 290 - 302
    - BERKOWITZ et al., Org. Lett., (20040000), vol. 6, pages 4921 - 4924
    - CRICH et al., Tetrahedron, (19980000), vol. 54, pages 8321 - 8348
    - KIM et al., J. Am. Chem. Soc., (20080000), vol. 130, pages 8537 - 8547
    - SRIVASTA et al., Tetrahedron Letters, (19790000), vol. 35, pages 3269 - 3272
    - HODOSI et al., J. Am. Chem. Soc., (19970000), vol. 119, pages 2335 - 2336
    - NICOLAOU et al., J. Am. Chem. Soc., (19970000), vol. 119, pages 9057 - 9058
    - GARMAN et al., J. Mol. Biol., (20040000), vol. 337, pages 319 - 335
    - GARMAN et al., Mol. Genet. Metabol., (20020000), vol. 77, pages 3 - 11
    - MATSUZAWA et al., Hum. Genet., (20050000), vol. 117, pages 317 - 328
    - MARTINIUK et al., Proc. Natl. Acad. Sci. USA, (19860000), vol. 83, pages 9641 - 9644
    - HOEFSLOOT et al., Biochem. J., (19900000), vol. 272, pages 493 - 497
    - MORELAND et al., J. Biol. Chem., (20050000), vol. 280, pages 6780 - 6791
    - "GenBank", Database accession no. NM_000152
    - LOVERING et al., J. Biol. Chem., (20050000), vol. 280, pages 2105 - 2115
    - LANSMANN et al., Eur. J. Biochem., (20030000), vol. 270, pages 1076 - 1088
    - SETO et al., Protein Sci., (20040000), vol. 13, pages 3172 - 3186
    - QIU et al., J. Biol. Chem., (20030000), vol. 278, pages 32744 - 32752
    - TAKAHASHI et al., Tokohu J. Exp. Med., (20050000), vol. 206, pages 333 - 340
    - "GenBank", Database accession no. AI587087
    - SCOTT et al., Proc. Natl. Acad. Sci USA, (19910000), vol. 88, pages 9695 - 9699
    - SCOTT et al., Genomics, (19920000), vol. 13, pages 1311 - 1313
    - SCOTT et al., Hum. Mutat., (19950000), vol. 6, pages 288 - 302
    - REMPEL et al., Mol. Genet. Metab., (20050000), vol. 85, pages 28 - 37
    - DURAND et al., Glycobiology, (19970000), vol. 7, pages 277 - 284
    - BEESLEY et al., Hum. Genet., (20010000), vol. 109, pages 503 - 511
    - BROOKS et al., Glycobiology, (20010000), vol. 11, pages 741 - 750
    - NIEMAN et al., Biochemistry, (20030000), vol. 42, pages 8054 - 8065
    - FLOMEN et al., Hum. Mol. Genet., (19930000), vol. 2, pages 5 - 10
    - ROBERTS et al., J. Med. Genet., (19890000), vol. 26, pages 309 - 313
    - WILSON et al., Proc. Natl. Acad. Sci. USA, (19900000), vol. 87, pages 8531 - 8535
    - WILSON et al., Genomics, (19930000), vol. 17, pages 773 - 775
    - SUKEGWA-HAYASAKA et al., J. Inherit. Metab. Dis, (20060000), vol. 29, pages 755 - 761
    - KIM et al., Hum. Mutat., (20030000), vol. 21, pages 193 - 201
    - LITJENS et al., Hum. Mut., (19920000), vol. 1, pages 397 - 402
    - PETERS et al., J. Biol. Chem., (19900000), vol. 265, pages 3374 - 3381
    - SCHUCHMAN et al., Genomics, (19900000), vol. 6, pages 149 - 158
    - BOND et al., Structure, (19970000), vol. 15, pages 277 - 289
    - ZHU et al., Biochem. J., (20050000), vol. 389, pages 619 - 628
    - ZHU et al., J. Biol. Chem., (20040000), vol. 279, pages 50336 - 50341
    - WANG et al., Proc. Natl. Acad. Sci. USA, (20030000), vol. 100, pages 56 - 61
    - LI et al., Clin. Chem., (20040000), vol. 50, pages 1785 - 1796
    - CIVALLERO et al., Clin. Chim. Acta, (20060000), vol. 372, pages 98 - 102
    - VAN DIGGELEN et al., J. Inherit. Metab. Dis., (20050000), vol. 28, pages 733 - 741
    - DOWNING et al., Plant Biotechnol., (20060000), vol. 4, pages 169 - 181
    - VOZNYI et al., J. Inherit. Metab. Dis., (20010000), vol. 24, pages 675 - 80
    - MURRAY et al., Mol. Genet. Metab., (20070000), vol. 90, pages 307 - 312
    - BROOKS et al., J. Inher. Metab. Dis., (19910000), vol. 14, pages 5 - 12
    - KIKUCHI et al., J. Clin. Invest., (19980000), vol. 101, pages 827 - 33
    - KAKKIS et al., Mol. Genet. Metab., (20010000), vol. 72, pages 199 - 208
    - LOANNOU et al., Am. J. Hum. Genet., (20010000), vol. 68, pages 14 - 25
    - HORINOUCHI et al., Nat. Genet., (19950000), vol. 10, pages 288 - 293
    - BERGE et al., J. Pharm. Sci., (19770000), vol. 66, pages 1 - 19
    - KAKKIS et al., Proc. Natl. Acad. Sci. U.S.A., (20040000), vol. 101, pages 829 - 834
    - UMPATHYSIVAM et al., Clin. Chem., (20010000), vol. 47, pages 1378 - 1383
    - MACDERMOTT et al., J. Med. Genet., (20010000), vol. 38, pages 750 - 760
    - PEKARI et al., J. Org. Chem., (20010000), vol. 66, page 7432
    - YAMAZAKI et al., Carb. Res., (19900000), vol. 201, page 31
    - HENG et al., J. Carb. Chem., (20010000), vol. 20, page 285
    - MAYER et al., EurJ. Org. Chem., (19990000), vol. 10, page 2563
    - ZHU et al., Biochem J, (20050000), vol. 389, pages 619 - 628
    - RABEN et al., J. Biol. Chem., (19980000), vol. 273, no. 30, pages 19086 - 92
    - LEE et al., Pharm. Res., (20030000), vol. 20, pages 818 - 825
 US20070885457
 US20070885471
 US20080122851
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.