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Extract from the Register of European Patents

EP About this file: EP3721896

EP3721896 - EPIDERMAL GROWTH FACTOR (EGF) AND VARIANTS THEREOF FOR TREATING OR PREVENTING INFLAMMATORY DEMYELINATING DISORDERS [Right-click to bookmark this link]
Former [2020/42]EPIDERMAL GROWTH FACTOR (EGF) AND VARIANTS THEREOF FOR MEDICAL USES IN NEURO-DE/REGENERATION
[2023/27]
StatusThe patent has been granted
Status updated on  27.10.2023
Database last updated on 30.09.2024
FormerGrant of patent is intended
Status updated on  14.06.2023
FormerExamination is in progress
Status updated on  21.01.2022
FormerRequest for examination was made
Status updated on  09.04.2021
FormerThe application has been published
Status updated on  11.09.2020
Most recent event   Tooltip02.08.2024Lapse of the patent in a contracting state
New state(s): SK		published on 04.09.2024  [2024/36]
Applicant(s)For all designated states
Scalabrino, Giuseppe
Via della Braida 10
20122 Milano / IT
For all designated states
Nicoletti, Ferdinando
Via Luigi Sturzo nr. 3
95021 Aci Castello, Catania / IT
For all designated states
Lang, Alois Bernhard
Hauptstrasse 36a
3033 Wohlen b. Bern / CH
For all designated states
Curtin, Francois
Avenue de la Forteaille 20
1292 Chambesy / CH
[2020/42]
Inventor(s)01 / see applicant
...
 [2020/42]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[2020/42]
Application number, filing date19167967.908.04.2019
[2020/42]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3721896
Date:14.10.2020
Language:EN
[2020/42]
Type: B1 Patent specification 
No.:EP3721896
Date:29.11.2023
Language:EN
[2023/48]
Search report(s)(Supplementary) European search report - dispatched on:EP04.10.2019
ClassificationIPC:A61K38/18, A61P25/28, G01N33/68
[2020/42]
CPC:
A61K38/1808 (EP); A61P25/28 (EP); G01N33/68 (EP);
G01N33/6896 (EP); G01N2333/485 (EP); G01N2800/28 (EP);
G01N2800/285 (EP); G01N2800/50 (EP) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/19]  
Former [2020/42]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
TitleGerman:EPIDERMALER WACHSTUMSFAKTOR (EGF) UND VARIANTEN DAVON ZUR BEHANDLUNG ODER VORBEUGUNG VON INFLAMMATORISCHEN DEMYELINISIERENDEN ERKRANKUNGEN[2023/48]
English:EPIDERMAL GROWTH FACTOR (EGF) AND VARIANTS THEREOF FOR TREATING OR PREVENTING INFLAMMATORY DEMYELINATING DISORDERS[2023/27]
French:FACTEUR DE CROISSANCE ÉPIDERMIQUE (EGF) ET SES VARIANTES POUR LE TRAITEMENT OU LA PRÉVENTION DE TROUBLES INFLAMMATOIRES DE DEMYELINISATION[2023/27]
Former [2020/42]EPIDERMALER WACHSTUMSFAKTOR (EGF) UND VARIANTEN DAVON FÜR MEDIZINISCHE VERWENDUNGEN IN DER NEURO-DE/REGENERATION
Former [2020/42]EPIDERMAL GROWTH FACTOR (EGF) AND VARIANTS THEREOF FOR MEDICAL USES IN NEURO-DE/REGENERATION
Former [2020/42]FACTEUR DE CROISSANCE ÉPIDERMIQUE (EGF) ET SES VARIANTES POUR UTILISATIONS MÉDICALES EN NEURO-DÉ/RÉGÉNÉRATION
Examination procedure07.04.2021Amendment by applicant (claims and/or description)
07.04.2021Examination requested  [2021/19]
07.04.2021Date on which the examining division has become responsible
25.01.2022Despatch of a communication from the examining division (Time limit: M06)
15.07.2022Reply to a communication from the examining division
15.06.2023Communication of intention to grant the patent
25.10.2023Fee for grant paid
25.10.2023Fee for publishing/printing paid
25.10.2023Receipt of the translation of the claim(s)
Fees paidRenewal fee
26.04.2021Renewal fee patent year 03
29.03.2022Renewal fee patent year 04
29.03.2023Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCZ29.11.2023
HR29.11.2023
PL29.11.2023
RO29.11.2023
RS29.11.2023
SK29.11.2023
SM29.11.2023
NO29.02.2024
GR01.03.2024
IS29.03.2024
[2024/36]
Former [2024/35]CZ29.11.2023
HR29.11.2023
PL29.11.2023
RO29.11.2023
RS29.11.2023
SM29.11.2023
NO29.02.2024
GR01.03.2024
IS29.03.2024
Former [2024/33]HR29.11.2023
PL29.11.2023
RS29.11.2023
SM29.11.2023
NO29.02.2024
GR01.03.2024
IS29.03.2024
Former [2024/25]HR29.11.2023
PL29.11.2023
RS29.11.2023
NO29.02.2024
GR01.03.2024
IS29.03.2024
Former [2024/20]GR01.03.2024
IS29.03.2024
Documents cited:Search[X]US2002004039  (REID JAMES STEVEN [US], et al) [X] 1,2,8-13 * paragraphs [0074] , [0 78]; claims 1, 3 *;
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 [XY]EP1889852  (UNIV PAIS VASCO [ES]) [X] 1,2,8-13 * paragraphs [0010] - [0013] - [0 57] , [0058]; claims 23-26, 28 * [Y] 1-15;
 [XY]  - DEL BARCO DIANA GARCÍA ET AL, "Coadministration of epidermal growth factor and growth hormone releasing peptide-6 improves clinical recovery in experimental autoimmune encephalitis.", RESTORATIVE NEUROLOGY AND NEUROSCIENCE 2011, (2011), vol. 29, no. 4, ISSN 1878-3627, pages 243 - 252, XP055619892 [X] 1,2,7-13 * table 1 * [Y] 1-15

DOI:   http://dx.doi.org/10.3233/RNN-2011-0595
 [X]  - GOVINDAIAH VINUKONDA ET AL, "Epidermal growth factor preserves myelin and promotes astrogliosis after intraventricular hemorrhage : Epidermal Growth Factor and IVH", GLIA, (20160729), vol. 64, no. 11, doi:10.1002/glia.23037, ISSN 0894-1491, pages 1987 - 2004, XP055620010 [X] 1,2,8-10 * page 1988, column r, paragraph 3 *

DOI:   http://dx.doi.org/10.1002/glia.23037
 [Y]  - ALMAZAN G ET AL, "Epidermal growth factor and bovine growth hormone stimulate differentiation and myelination of brain cell aggregates in culture", DEVELOPMENTAL BRAIN RESEARCH, ELSEVIER SCIENCE BV, AMSTERDAM, NL, vol. 21, no. 2, doi:10.1016/0165-3806(85)90214-7, ISSN 0165-3806, (19850801), pages 257 - 264, (19850801), XP025413654 [Y] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1016/0165-3806(85)90214-7
 [Y]  - KNAPP P E ET AL, "Epidermal growth factor promotes oligodendrocyte process formation and regrowth after injury", EXPERIMENTAL CELL RESEARCH, ELSEVIER, AMSTERDAM, NL, (20040318), vol. 296, no. 2, doi:10.1016/J.YEXCR.2004.02.007, ISSN 0014-4827, pages 135 - 144, XP002395583 [Y] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.yexcr.2004.02.007
 [YD]  - MARTA TEJERA-ALHAMBRA ET AL, "Plasma Biomarkers Discriminate Clinical Forms of Multiple Sclerosis", PLOS ONE, (20150603), vol. 10, no. 6, doi:10.1371/journal.pone.0128952, page e0128952, XP055619754 [YD] 15 * the whole document *

DOI:   http://dx.doi.org/10.1371/journal.pone.0128952
 [A]  - SCALABRINO GIUSEPPE ET AL, "Relationships between cobalamin, epidermal growth factor, and normal prions in the myelin maintenance of central nervous system", INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND CELL BIOLOGY, PERGAMON, GB, (20140917), vol. 55, doi:10.1016/J.BIOCEL.2014.09.011, ISSN 1357-2725, pages 232 - 241, XP029020040 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.biocel.2014.09.011
 [XP]  - NICOLETTI FERDINANDO ET AL, "Prevention of clinical and histological signs of MOG-induced experimental allergic encephalomyelitis by prolonged treatment with recombinant human EGF", JOURNAL OF NEUROIMMUNOLOGY, (20190508), vol. 332, doi:10.1016/J.JNEUROIM.2019.05.006, ISSN 0165-5728, pages 224 - 232, XP085694222 [XP] 1-13 * paragraph [2.2.3; 3.2.3; 3.2.4]; table 1 *

DOI:   http://dx.doi.org/10.1016/j.jneuroim.2019.05.006
by applicantWO9203476
 US5268164
 WO9325234
 WO9406920
 US5506206
 US5527527
 US5686416
 US5833988
 US5977307
 US6015555
 US6329508
 EP1870106
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