Extract from the Register of European Patents

EP About this file: EP3539548

EP3539548 - COMPOSITION FOR INDUCING PROLIFERATION OR ACCUMULATION OF REGULATORY CELLS [Right-click to bookmark this link]
StatusThe patent has been granted
Status updated on  27.03.2020
Database last updated on 20.03.2026
FormerGrant of patent is intended
Status updated on  26.02.2020
FormerExamination is in progress
Status updated on  17.08.2019
FormerRequest for examination was made
Status updated on  16.08.2019
Most recent event   Tooltip12.03.2026Change: Decision (+date) in appeal procedure 
12.03.2026New entry: Decision (+date) in appeal procedure 
Applicant(s)For all designated states
The University of Tokyo
3-1, Hongo 7-chome
Bunkyo-ku
Tokyo 113-8654 / JP
[2019/38]
Inventor(s)01 / HONDA, Kenya
RIKEN Center for Integrative Medical Sciences (IMS
RCAI)
Laboratory for Gut Homeostasis
1-7-22 Suehiro-cho, Tsurumi-ku
Yokohama, 230-0045 / JP
02 / ATARASHI, Koji
RIKEN Center for Integrative Medical Sciences (IMS
RCAI)
Laboratory for Gut Homeostasis
1-7-22 Suehiro-cho, Tsurumi-ku
Yokohama, 230-0045 / JP
03 / ITOH, Kikuji
Laboratory for Gut Homeostasis
RIKEN Center for Integrative Medical Sciences
(IMS RCAI)
1-7-22 Suehiro-cho, Tsurumi-ku
Yokohama 230-0045 / JP
04 / TANOUE, Takeshi
RIKEN Center for Integrative Medical Sciences (IMS
RCAI)
Laboratory for Gut Homeostasis
1-7-22 Suehiro-cho, Tsurumi-ku
Yokohama, 230-0045 / JP
 [2019/45]
Former [2019/38]01 / Honda, Kenya
RIKEN Center for Integrative Medical Sciences (IMS
RCAI)
Laboratory for Gut Homeostasis
1-7-22 Suehiro-cho, Tsurumi-ku
Yokohama, 230-0045 / JP
02 / Atarashi, Koji
RIKEN Center for Integrative Medical Sciences (IMS
RCAI)
Laboratory for Gut Homeostasis
1-7-22 Suehiro-cho, Tsurumi-ku
Yokohama, 230-0045 / JP
03 / Itoh, Kikuji
c/o THE UNIVERSITY OF TOKYO
3-1, Hongo 7-chome
Bunkyo-ku
Tokyo, 113-8654 / JP
04 / Tanoue, Takeshi
RIKEN Center for Integrative Medical Sciences (IMS
RCAI)
Laboratory for Gut Homeostasis
1-7-22 Suehiro-cho, Tsurumi-ku
Yokohama, 230-0045 / JP
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
[2019/38]
Application number, filing date19168383.803.06.2011
[2019/38]
Priority number, dateJP2010012913404.06.2010         Original published format: JP 2010129134
WO2010JP7174603.12.2010         Original published format: PCT/JP2010/071746
[2019/38]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3539548
Date:18.09.2019
Language:EN
[2019/38]
Type: B1 Patent specification 
No.:EP3539548
Date:29.04.2020
Language:EN
[2020/18]
Search report(s)(Supplementary) European search report - dispatched on:EP26.07.2019
ClassificationIPC:A61K35/742
[2019/38]
CPC:
A61K39/39 (EP,US); A61K35/742 (US); A01K67/0275 (EP,US);
A61K35/74 (EP,US); A61K39/0008 (US); A61K39/08 (US);
A61K45/00 (US); A61K45/06 (EP,US); A61K9/0053 (US);
A61K9/48 (US); A61P1/00 (EP); A61P1/04 (EP);
A61P1/12 (EP); A61P19/02 (EP); A61P25/00 (EP);
A61P29/00 (EP); A61P3/10 (EP); A61P31/00 (EP);
A61P31/04 (EP); A61P37/00 (EP); A61P37/02 (EP);
A61P37/04 (EP); A61P37/06 (EP); A61P37/08 (EP);
A61P43/00 (EP); C12Q1/689 (US); G01N33/505 (EP,US);
A01K2217/072 (EP); A01K2217/203 (EP); A01K2227/105 (EP);
A01K2267/0325 (EP,US); A61K2039/52 (US); A61K2039/542 (US);
A61K2039/55594 (EP,US); A61K2039/57 (US); A61K2039/577 (EP);
A61K35/00 (EP,US); C12Q2600/158 (US); G01N2333/33 (EP,US);
G01N2500/10 (EP,US) (-)
C-Set:
A61K35/74, A61K2300/00 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/38]
TitleGerman:ZUSAMMENSETZUNG ZUR INDUZIERUNG DER PROLIFERATION ODER AKKUMULATION VON REGULATORISCHEN ZELLEN[2019/38]
English:COMPOSITION FOR INDUCING PROLIFERATION OR ACCUMULATION OF REGULATORY CELLS[2019/38]
French:COMPOSITION POUR INDUIRE LA PROLIFÉRATION OU L'ACCUMULATION DE CELLULES RÉGULATRICES[2019/38]
Examination procedure10.04.2019Examination requested  [2019/38]
26.07.2019Date on which the examining division has become responsible
21.08.2019Despatch of a communication from the examining division (Time limit: M04)
25.11.2019Reply to a communication from the examining division
27.02.2020Communication of intention to grant the patent
18.03.2020Fee for grant paid
18.03.2020Fee for publishing/printing paid
18.03.2020Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP11728077.6  / EP2575835
EP16188203.0  / EP3178483
Opposition(s)Opponent(s)01  29.01.2021  02.02.2021  ADMISSIBLE
Société des Produits Nestlé S.A.
Avenue Nestlé 55
1800 Vevey / CH
Opponent's representative
Elkington and Fife LLP
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
 02  29.01.2021  02.02.2021  ADMISSIBLE
Rieck, Markus
Die Rappenwiesen 25
61350 Bad Homburg / DE
Opponent's representative
Fuchs Patentanwälte Partnerschaft mbB
Tower 185
Friedrich-Ebert-Anlage 35-37
60327 Frankfurt am Main / DE
 03  29.01.2021  02.02.2021  ADMISSIBLE
Potter Clarkson LLP
The Belgrave Centre
Talbot Street
Nottingham NG1 5GG / GB
 04  29.01.2021  02.02.2021  WITHDRAWN
STRAWMAN LIMITED
Orchard Lea
Horns Lane
Combe
Witney, Oxfordshire OX29 8NH / GB
 [2024/19]
Former [2024/18]
Opponent(s)01  29.01.2021  02.02.2021  ADMISSIBLE
Société des Produits Nestlé S.A.
Avenue Nestlé 55
1800 Vevey / CH
Opponent's representative
Elkington and Fife LLP
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
 02  29.01.2021  02.02.2021  ADMISSIBLE
Rieck, Markus
Die Rappenwiesen 25
61350 Bad Homburg / DE
Opponent's representative
Fuchs Patentanwälte Partnerschaft mbB
Tower 185
Friedrich-Ebert-Anlage 35-37
60327 Frankfurt am Main / DE
 03  29.01.2021  02.02.2021  ADMISSIBLE
Potter Clarkson LLP
The Belgrave Centre
Talbot Street
Nottingham NG1 5GG / GB
 04  29.01.2021  02.02.2021  ADMISSIBLE
STRAWMAN LIMITED
Orchard Lea
Horns Lane
Combe
Witney, Oxfordshire OX29 8NH / GB
Former [2024/10]
Opponent(s)01  29.01.2021  02.02.2021  ADMISSIBLE
Société des Produits Nestlé S.A.
Avenue Nestlé 55
1800 Vevey / CH
Opponent's representative
Elkington and Fife LLP
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
 02  29.01.2021  02.02.2021  ADMISSIBLE
Rieck, Markus
Die Rappenwiesen 25
61350 Bad Homburg / DE
Opponent's representative
Fuchs Patentanwälte Partnerschaft mbB
Tower 185
Friedrich-Ebert-Anlage 35-37
60327 Frankfurt am Main / DE
 03  29.01.2021  02.02.2021  ADMISSIBLE
Potter Clarkson LLP
The Belgrave Centre
Talbot Street
Nottingham NG1 5GG / GB
 04  29.01.2021  02.02.2021  ADMISSIBLE
STRAWMAN LIMITED
Orchard Lea
Horns Lane
Combe
Witney, Oxfordshire OX29 8NH / GB
Former [2021/10]
Opponent(s)01  29.01.2021  02.02.2021  ADMISSIBLE
Société des Produits Nestlé S.A.
Avenue Nestlé 55
1800 Vevey / CH
Opponent's representative
Elkington and Fife LLP
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
 02  29.01.2021  02.02.2021  ADMISSIBLE
Rieck, Markus
Die Rappenwiesen 25
61350 Bad Homburg / DE
Opponent's representative
Fuchs Patentanwälte Partnerschaft mbB
Westhafenplatz 1
60327 Frankfurt am Main / DE
 03  29.01.2021  02.02.2021  ADMISSIBLE
Potter Clarkson LLP
The Belgrave Centre
Talbot Street
Nottingham NG1 5GG / GB
 04  29.01.2021  02.02.2021  ADMISSIBLE
STRAWMAN LIMITED
Orchard Lea
Horns Lane
Combe
Witney, Oxfordshire OX29 8NH / GB
Opponent's representative
Brand Murray Fuller LLP
50 Eastcastle Street
London W1W 8EA / GB
deletedDeletion: Legal effect of rejection of opposition [ N /P ]
10.02.2021Invitation to proprietor to file observations on the notice of opposition
20.07.2021Reply of patent proprietor to notice(s) of opposition
16.10.2023Date of oral proceedings
13.11.2023Despatch of minutes of oral proceedings
13.11.2023Date of despatch of rejection of opposition
Appeal following opposition15.01.2024Appeal received No.  T0100/24
15.01.2024Payment of appeal fee
13.03.2024Statement of grounds filed
10.03.2026Result of appeal procedure: REVOCATION OF PATENT AT PROPRIETOR'S REQUEST
18.03.2026Despatch of the decision of the Board of Appeal
12.01.2024Appeal received No.  T0100/24
12.01.2024Payment of appeal fee
12.03.2024Statement of grounds filed
10.03.2026Result of appeal procedure: REVOCATION OF PATENT AT PROPRIETOR'S REQUEST
18.03.2026Despatch of the decision of the Board of Appeal
10.03.2026Date of oral proceedings
Fees paidRenewal fee
10.04.2019Renewal fee patent year 03
10.04.2019Renewal fee patent year 04
10.04.2019Renewal fee patent year 05
10.04.2019Renewal fee patent year 06
10.04.2019Renewal fee patent year 07
10.04.2019Renewal fee patent year 08
10.04.2019Renewal fee patent year 09
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Lapses during opposition  TooltipHU03.06.2011
AL29.04.2020
AT29.04.2020
CY29.04.2020
CZ29.04.2020
DK29.04.2020
EE29.04.2020
FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
MC29.04.2020
MK29.04.2020
MT29.04.2020
RO29.04.2020
RS29.04.2020
SI29.04.2020
SK29.04.2020
SM29.04.2020
TR29.04.2020
IE03.06.2020
LU03.06.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
[2023/41]
Former [2022/33]HU03.06.2011
AL29.04.2020
AT29.04.2020
CY29.04.2020
CZ29.04.2020
DK29.04.2020
EE29.04.2020
FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
MC29.04.2020
MK29.04.2020
MT29.04.2020
RO29.04.2020
RS29.04.2020
SK29.04.2020
SM29.04.2020
TR29.04.2020
IE03.06.2020
LU03.06.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2022/27]HU03.06.2011
AL29.04.2020
AT29.04.2020
CY29.04.2020
CZ29.04.2020
DK29.04.2020
EE29.04.2020
FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
MC29.04.2020
MT29.04.2020
RO29.04.2020
RS29.04.2020
SK29.04.2020
SM29.04.2020
TR29.04.2020
IE03.06.2020
LU03.06.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/20]AL29.04.2020
AT29.04.2020
CZ29.04.2020
DK29.04.2020
EE29.04.2020
FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
MC29.04.2020
RO29.04.2020
RS29.04.2020
SK29.04.2020
SM29.04.2020
IE03.06.2020
LU03.06.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/15]AL29.04.2020
AT29.04.2020
CZ29.04.2020
DK29.04.2020
EE29.04.2020
FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
MC29.04.2020
RO29.04.2020
RS29.04.2020
SK29.04.2020
SM29.04.2020
LU03.06.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/10]AL29.04.2020
AT29.04.2020
CZ29.04.2020
DK29.04.2020
EE29.04.2020
FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
MC29.04.2020
RO29.04.2020
RS29.04.2020
SK29.04.2020
SM29.04.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/09]AL29.04.2020
AT29.04.2020
CZ29.04.2020
DK29.04.2020
EE29.04.2020
FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
MC29.04.2020
RO29.04.2020
RS29.04.2020
SM29.04.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/08]AL29.04.2020
DK29.04.2020
FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
RO29.04.2020
RS29.04.2020
SM29.04.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/04]AL29.04.2020
FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
RS29.04.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/01]FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
RS29.04.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2020/51]FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
RS29.04.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2020/50]FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2020/48]FI29.04.2020
LT29.04.2020
NO29.07.2020
IS29.08.2020
PT31.08.2020
Former [2020/47]LT29.04.2020
NO29.07.2020
IS29.08.2020
Former [2020/46]IS29.08.2020
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DOI:   http://dx.doi.org/10.1016/j.smim.2011.01.010
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OppositionUS5599795
 EP2575835
 EP3539548
 WO2004085628
 WO2013080561
 JP2009084215
 EP1955706
 EP1749538
 WO2009050486
 DE102006062250
 US5599795
   KROGIUS-KURIKKA LOTTA; KASSINEN ANNA; PAULIN LARS; CORANDER JUKKA; MKIVUOKKO HARRI; TUIMALA JARNO; PALVA AIRI: "Sequence analysis of percent G+C fraction libraries of human faecal bacterial DNA reveals a high number of Actinobacteria", B MC MICROBIOLOGY, vol. 9, no. 68, 2009, pages 1 - 13, XP021048239

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