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Extract from the Register of European Patents

EP About this file: EP3574907

EP3574907 - A DUAL NK-1/NK-3 RECEPTOR ANTAGONIST FOR THE TREATMENT OF SEX-HORMONE-DEPENDENT DISEASES [Right-click to bookmark this link]
Former [2019/49]AN NK-1/NK-3 RECEPTOR ANTAGONIST FOR THE TREATMENT OF SEX-HORMONE-DEPENDENT DISEASES
[2023/10]
StatusThe patent has been granted
Status updated on  21.07.2023
Database last updated on 18.05.2024
FormerGrant of patent is intended
Status updated on  19.03.2023
FormerExamination is in progress
Status updated on  28.08.2020
FormerRequest for examination was made
Status updated on  05.06.2020
FormerThe application has been published
Status updated on  01.11.2019
Most recent event   Tooltip17.05.2024Lapse of the patent in a contracting state
New state(s): CZ, ES, RO, SK
published on 19.06.2024 [2024/25]
Applicant(s)For all designated states
KaNDy Therapeutics Limited
400 South Oak Way
Reading, Berkshire RG2 6AD / GB
[2021/24]
Former [2019/49]For all designated states
NeRRe Therapeutics Limited
Stevenage Bioscience Catalyst
Office F25 Incubator Building
Gunnels Wood Road
Stevenage Herts
SG1 2FX / GB
Inventor(s)01 / TROWER, Mike
P.O. Box
c/o NeRRe Therapeutics Limited
Stevenage Bioscience Catalyst
Incubator Building, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2FX / GB
 [2019/49]
Representative(s)Murgitroyd & Company
165-169 Scotland Street
Glasgow G5 8PL / GB
[N/P]
Former [2023/34]Murgitroyd & Company
Murgitroyd House
165-169 Scotland Street
Glasgow G5 8PL / GB
Former [2019/49]Murgitroyd & Company
Scotland House
165-169 Scotland Street
Glasgow G5 8PL / GB
Application number, filing date19186140.016.05.2016
[2019/49]
Priority number, dateUS201562162870P18.05.2015         Original published format: US 201562162870 P
[2019/49]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3574907
Date:04.12.2019
Language:EN
[2019/49]
Type: B1 Patent specification 
No.:EP3574907
Date:23.08.2023
Language:EN
[2023/34]
Search report(s)(Supplementary) European search report - dispatched on:EP02.10.2019
ClassificationIPC:A61K31/5383, A61K45/06, A61P5/24, A61P15/00, A61P15/02, A61P15/12, A61P43/00, A61K9/00
[2019/49]
CPC:
A61K31/5383 (EP,KR,US); A61K31/40 (US); A61K31/436 (KR,US);
A61K31/4436 (KR,US); A61K31/4439 (KR,US); A61K31/444 (KR,US);
A61K31/5365 (KR,RU,US); A61K45/06 (EP,US); A61K9/00 (US);
A61P15/00 (EP,RU,US); A61P15/02 (EP,US); A61P15/12 (EP,US);
A61P43/00 (EP,RU,US); A61P5/24 (EP,KR,RU,US); A61P5/26 (KR);
C07D498/04 (RU); A61K9/0095 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/28]  
Former [2019/49]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
TitleGerman:EIN NK1/NK3-REZEPTORANTAGONIST ZUR BEHANDLUNG VON GESCHLECHTSHORMONABHÄNGIGEN ERKRANKUNGEN[2023/13]
English:A DUAL NK-1/NK-3 RECEPTOR ANTAGONIST FOR THE TREATMENT OF SEX-HORMONE-DEPENDENT DISEASES[2023/10]
French:UN ANTAGONISTE DES RÉCEPTEURS NK1/NK3 DESTINÉ AU TRAITEMENT DE MALADIES DÉPENDANTES DES HORMONES SEXUELLES[2019/49]
Former [2019/49]EIN NK1/NK3-REZEPTORANTAGONIST ZUR BEHANDLUNG VON GESCHLECHTSHORMONABHÄNGIGEN ERKRANKUNGEN
Former [2019/49]AN NK-1/NK-3 RECEPTOR ANTAGONIST FOR THE TREATMENT OF SEX-HORMONE-DEPENDENT DISEASES
Examination procedure02.06.2020Amendment by applicant (claims and/or description)
02.06.2020Examination requested  [2020/28]
02.06.2020Date on which the examining division has become responsible
28.08.2020Despatch of a communication from the examining division (Time limit: M06)
22.02.2021Reply to a communication from the examining division
02.06.2022Despatch of a communication from the examining division (Time limit: M04)
02.09.2022Reply to a communication from the examining division
20.03.2023Communication of intention to grant the patent
12.07.2023Fee for grant paid
12.07.2023Fee for publishing/printing paid
12.07.2023Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP16723107.5  / EP3297631
Fees paidRenewal fee
12.07.2019Renewal fee patent year 03
12.07.2019Renewal fee patent year 04
30.03.2020Renewal fee patent year 05
13.05.2021Renewal fee patent year 06
26.04.2022Renewal fee patent year 07
14.03.2023Renewal fee patent year 08
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCZ23.08.2023
ES23.08.2023
HR23.08.2023
PL23.08.2023
RO23.08.2023
RS23.08.2023
SK23.08.2023
SM23.08.2023
NO23.11.2023
GR24.11.2023
IS23.12.2023
[2024/23]
Former [2024/20]HR23.08.2023
PL23.08.2023
RS23.08.2023
SM23.08.2023
NO23.11.2023
GR24.11.2023
IS23.12.2023
Former [2024/10]HR23.08.2023
PL23.08.2023
RS23.08.2023
NO23.11.2023
GR24.11.2023
IS23.12.2023
Former [2024/09]NO23.11.2023
GR24.11.2023
IS23.12.2023
Former [2024/08]NO23.11.2023
GR24.11.2023
Documents cited:Search[Y]WO02089802  (SCHERING CORP [US]) [Y] 1-15 * abstract * * page 1, line 20 - line 39 * * page 4, line 11 - page 6, line 27 * * page 9, line 25 - line 31 * * page 28, line 31 - page 31, line 36 * * claims 1-22 *;
 [AD]WO2005002577  (HOFFMANN LA ROCHE [CH], et al) [AD] 1-15 * abstract * * page 4, line 10 - line 13 * * page 105, Example 155 * * example 155 *;
 [A]WO2005097774  (JANSSEN PHARMACEUTICA NV [BE], et al) [A] 1-15 * abstract * * page 1, line 5 - line 15 * * page 28, line 31 - page 29, line 2 * * page 64, Table 8, compound 8 * * claim 14 *;
 [AD]WO2007028654  (SMITHKLINE BEECHAM CORP [US], et al) [AD] 1-15 * abstract * * example 102 * * page 184, line 42 - page 185, line 17 * * claims 1-36 *;
 [YD]WO2011023733  (GLAXOSMITHKLINE LLC [US], et al) [YD] 1-15 * abstract * * page 1, line 5 - line 19 * * page 2, line 205 - page 21 * * claims 1-13 *;
 [A]  - CATERINA BISSANTZ ET AL, "Identification of a Crucial Amino Acid in the Helix Position 6.51 of Human Tachykinin Neurokinin 1 and 3 Receptors Contributing to the Insurmountable Mode of Antagonism by Dual NK 1 /NK 3 Antagonists", JOURNAL OF MEDICINAL CHEMISTRY, US, (20120614), vol. 55, no. 11, doi:10.1021/jm2017072, ISSN 0022-2623, pages 5061 - 5076, XP055234123 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1021/jm2017072
Examination   - DOMINIQUE DE ZIEGLER ET AL, "Inflammation and uterine fibrosis: the possible role of chronic endometritis", FERTILITY AND STERILITY, AMSTERDAM, NL, (20190501), vol. 111, no. 5, doi:10.1016/j.fertnstert.2019.02.005, ISSN 0015-0282, pages 890 - 891, XP055724527

DOI:   http://dx.doi.org/10.1016/j.fertnstert.2019.02.005
    - Anon., "ICD-11 for Mortality and Morbidity Statistics : GA20.50 Heavy menstrual bleeding", (20190401), URL: https://icd.who.int/browse11/l-m/en#/http%3a%2f%2fid.who.int%2ficd%2fentity%2f609833590, (20230131), XP093019520
by applicantWO2004056799
 WO2004056805
 WO2005002577
 WO2005097794
 WO2006013050
 WO2007028654
 WO2008128891
 WO2011023733
 WO2011031571
 WO2011131571
    - BERTRANDGEPPETTI, Trends Pharmacol. Sci., (19960000), vol. 17, pages 255 - 259
    - Inactive Ingredient Guide, U.S. Food and Drug Administration (FDA) Center for Drug
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.