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EP3632426
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EP About this file: EP3632426
| EP3632426 - AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY [Right-click to bookmark this link] | Status | Examination is in progress Status updated on 11.08.2023 Database last updated on 15.06.2024 | |
| Former | Request for examination was made Status updated on 09.10.2020 | ||
| Former | The application has been published Status updated on 06.03.2020 | Most recent event Tooltip | 08.05.2024 | New entry: Despatch of examination report + time limit | Applicant(s) | For all designated states Pharma Cinq, LLC 1601 Research Boulevard Rockville, MD 20850 / US | [2024/23] |
| Former [2020/15] | For all designated states Wellstat Therapeutics Corporation 14200 Shady Grove Road, Suite 600 Rockville, MD 20850 / US | Inventor(s) | 01 /
SIMPSON, David M. 6611 Sulky Lane North Bethesda, MD Maryland 20852 / US | 02 /
ZERBY, Dennis Bryan 11733 Crystal Falls Drive Smithsburg, MD 21783 / US | 03 /
LU, Ming 13518 Broadfield Drive Bethesda, MD Maryland 20854 / US | 04 /
VON BORSTEL, Reid W. 10017 Sorrel Avenue Potomac, MD Maryland 20854 / US | 05 /
LI, Rui 16179 Black Rock Road Darnestown, MD Maryland 20874 / US | 06 /
READING, Julian 1509 Scotts Chase Drive Frederick, MD Maryland 21702 / US | 07 /
WOLPE, Stephen 18301 Clear Smoke Road Boyds, MD Maryland 20841 / US | 08 /
AMAN, Nureddin 1478 Kingstream Drive Herndon, VA Virginia 20170 / US | [2020/16] |
| Former [2020/15] | 01 /
SIMPSON, David M. 6611 Sulky Lane North Bethesda, MD Maryland 20852 / US | ||
| 02 /
ZERBY, Dennis Bryan 8651 Fort Mccord Road Chambersburg, PA Pennsylvania 17202 / US | |||
| 03 /
LU, Ming 13518 Broadfield Drive Bethesda, MD Maryland 20854 / US | |||
| 04 /
VON BORSTEL, Reid W. 10017 Sorrel Avenue Potomac, MD Maryland 20854 / US | |||
| 05 /
LI, Rui 16179 Black Rock Road Darnestown, MD Maryland 20874 / US | |||
| 06 /
READING, Julian 1509 Scotts Chase Drive Frederick, MD Maryland 21702 / US | |||
| 07 /
WOLPE, Stephen 18301 Clear Smoke Road Boyds, MD Maryland 20841 / US | |||
| 08 /
AMAN, Nureddin 1478 Kingstream Drive Herndon, VA Virginia 20170 / US | Representative(s) | Mathys & Squire The Shard 32 London Bridge Street London SE1 9SG / GB | [N/P] |
| Former [2020/15] | Gregson, Anna Louise Mathys & Squire LLP The Shard 32 London Bridge Street London SE1 9SG / GB | Application number, filing date | 19201890.1 | 31.01.2014 | [2020/15] | Priority number, date | US201361759512P | 01.02.2013 Original published format: US 201361759512 P | [2020/15] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP3632426 | Date: | 08.04.2020 | Language: | EN | [2020/15] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 31.01.2020 | Classification | IPC: | A61K31/337 | [2020/15] | CPC: |
C07D471/04 (EP,IL,US);
A61P29/00 (EP,RU);
C07D215/40 (EP,IL,KR,US);
A01N43/42 (IL,US);
A01N43/50 (IL,US);
A01N43/54 (IL,US);
A01N43/60 (IL,US);
A01N43/90 (IL,US);
A61K31/337 (EP,IL,US);
A61K31/40 (EP,IL,US);
A61K31/4164 (EP,IL,US);
A61K31/4184 (EP,IL,US);
A61K31/437 (EP,IL,US);
A61K31/44 (EP,IL,US);
A61K31/4425 (EP,IL,US);
A61K31/4706 (EP,IL,KR,US);
A61K31/4709 (EP,IL,US);
A61K31/472 (EP,IL,US);
A61K31/4745 (EP,IL,US);
A61K31/475 (EP,IL,US);
A61K31/4965 (EP,IL,US);
A61K31/498 (EP,IL,US);
A61K31/505 (EP,IL,US);
A61K31/517 (EP,IL,RU,US);
A61K31/555 (EP,IL,US);
A61K31/704 (EP,IL,US);
A61P31/10 (EP,RU);
A61P33/02 (EP,IL,US);
A61P35/00 (EP,IL,RU,US);
C07D209/12 (EP,IL,US);
C07D213/73 (EP,IL,US);
C07D213/74 (EP,IL,US);
C07D215/38 (EP,IL,KR,US);
C07D215/42 (EP,IL,US);
C07D215/44 (EP,IL,US);
C07D215/46 (EP,IL,US);
C07D233/60 (EP,IL,US);
C07D235/08 (EP,IL,US);
C07D239/42 (EP,IL,US);
C07D239/94 (EP,IL,RU,US);
C07D241/20 (EP,IL,US);
C07D241/44 (EP,IL,US);
C07D401/12 (EP,IL,US);
A61K2300/00 (IL);
Y02A50/30 (EP,US);
Y02P20/582 (EP,US)
(-)
| C-Set: |
A61K31/337, A61K2300/00 (US,EP);
A61K31/40, A61K2300/00 (EP,US);
A61K31/4164, A61K2300/00 (US,EP);
A61K31/4184, A61K2300/00 (EP,US);
A61K31/437, A61K2300/00 (EP,US);
A61K31/4425, A61K2300/00 (US,EP);
A61K31/44, A61K2300/00 (EP,US);
A61K31/4706, A61K2300/00 (US,EP);
A61K31/4709, A61K2300/00 (US,EP);
A61K31/472, A61K2300/00 (US,EP);
A61K31/4745, A61K2300/00 (US,EP);
A61K31/475, A61K2300/00 (US,EP);
A61K31/4965, A61K2300/00 (EP,US);
A61K31/498, A61K2300/00 (US,EP);
A61K31/505, A61K2300/00 (EP,US);
A61K31/517, A61K2300/00 (US,EP); | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2020/46] |
| Former [2020/15] | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR | Title | German: | AMINVERBINDUNGEN MIT ENTZÜNDUNGSHEMMENDER, FUNGIZIDER, ANTIPARASITÄRER UND ANTIKREBSWIRKUNG | [2020/15] | English: | AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY | [2020/15] | French: | COMPOSÉS D'AMINE PRÉSENTANT UNE ACTIVITÉ ANTI-INFLAMMATOIRE, ANTIFONGIQUE, ANTIPARASITAIRE ET ANTICANCÉREUSE | [2020/15] | Examination procedure | 06.10.2020 | Amendment by applicant (claims and/or description) | 06.10.2020 | Examination requested [2020/46] | 06.10.2020 | Date on which the examining division has become responsible | 07.05.2024 | Despatch of a communication from the examining division (Time limit: M04) | Parent application(s) Tooltip | EP14746786.4 / EP2950649 | Fees paid | Renewal fee | 08.10.2019 | Renewal fee patent year 03 | 08.10.2019 | Renewal fee patent year 04 | 08.10.2019 | Renewal fee patent year 05 | 08.10.2019 | Renewal fee patent year 06 | 27.01.2020 | Renewal fee patent year 07 | 28.06.2021 | Renewal fee patent year 08 | 27.06.2022 | Renewal fee patent year 09 | 28.07.2023 | Renewal fee patent year 10 | 26.01.2024 | Renewal fee patent year 11 | Penalty fee | Additional fee for renewal fee | 31.01.2021 | 08 M06 Fee paid on 28.06.2021 | 31.01.2022 | 09 M06 Fee paid on 27.06.2022 | 31.01.2023 | 10 M06 Fee paid on 28.07.2023 |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Stay/Interruption | 31.03.2023 | Interruption of proceedings. Reason: legal prevention of applicant | [2024/11] | 02.05.2024 | Resumption of proceedings | [2024/11] | Documents cited: | Search | [X]US4213987 (FUJII KATSUTOSHI [JP], et al) [X] 1,5,6,9,12 * compound 1, 2, 34, 91, 92, 96, 167, 217, 259, 274 *; | [X]US4331667 (SCHNEIDER RUPERT) [X] 1-4 * column 1, line 56-66; table in column 2 *; | [X]EP0520722 (ICI PLC [GB]) [X] 1,2,9,11 * table I, compound 1 and 4 *; | [X]WO9609294 (WELLCOME FOUND [GB], et al) [X] 1,2,9-11 * page 1, 1st paragraph; example 22, 39, 41, 44, 46, 49, 51 *; | [X]US6046206 (PAMUKCU RIFAT [US], et al) [X] 1,2,9,11 * example 59; column 1, line 9-10 *; | [X]WO2012079079 (HARVARD COLLEGE [US], et al) [X] 1,2,7,9-11* paragraph bridging page 1 and 2; page 20-24 *; | [A] - FIRESTONE R A ET AL, "LYSOSOMOTROPIC AGENTS. 7.1 BROAD-SPECTRUM ANTIFUNGAL ACTIVITY OF LYSOSOMOTROPIC DETERGENTS", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, (19870101), vol. 30, no. 8, doi:10.1021/JM00391A043, ISSN 0022-2623, pages 1519 - 1521, XP002050360 [A] 1-14 * table I-III * DOI: http://dx.doi.org/10.1021/jm00391a043 | [A] - MAHADEO A. SUKHAI ET AL, "Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors", JOURNAL OF CLINICAL INVESTIGATION, US, (20121203), vol. 123, no. 1, doi:10.1172/JCI64180, ISSN 0021-9738, pages 315 - 328, XP055278810 [A] 1-14 * table 2; figure 4 * DOI: http://dx.doi.org/10.1172/JCI64180 | [A] - RAYMOND FIRESTONE, "Lysosomotropic Agents. 1. Synthesis and Cytotaxic Action of Lysosomotropic Detergents", JOURNAL OF MEDICINAL CHEMISTRY, (19790901), vol. 22, no. 9, pages 1130 - 1133, XP055279491 [A] 1-14 * paragraph bridging page 1130 and 1131 * | [A] - SASHI NADANACIVA ET AL, "A high content screening assay for identifying lysosomotropic compounds", TOXICOLOGY IN VITRO., GB, (20101222), vol. 25, no. 3, doi:10.1016/j.tiv.2010.12.010, ISSN 0887-2333, pages 715 - 723, XP055279409 [A] 1-14 * table 2; figure 4; page 722, left hand column, 1st full paragraph * DOI: http://dx.doi.org/10.1016/j.tiv.2010.12.010 | [X] - SERGIY I. KOVALENKO, "Synthesis and Anticancer Activity of 2-(Alkyl-, Alkaryl-, Aryl-, Hetaryl-)[1,2,4]triazolo[1,5-c]quinazolines", SCIENTIA PHARMACEUTICA, Austria, (20130101), vol. 81, no. 2, doi:10.3797/scipharm.1211-08, ISSN 0036-8709, pages 359 - 391, XP055658898 [X] 1,5,9,11 * compound 3.35, 3.40, 3.41 * DOI: http://dx.doi.org/10.3797/scipharm.1211-08 | by applicant | - ALFORD JGSTANLEY PLTODDERUD GTRAMPOSCH KM, "Temporal infiltration of leukocyte subsets into mouse skin inflamed with phorbol ester", Agents Actions, (19920000), vol. 37, no. 3-4, pages 260 - 7 | - SWINDELL WRJOHNSTON ACARBAJAL SHAN GWOHN CLU JXING XNAIR RPVOORHEES JJELDER JT, "Genome-wide expression profiling of five mouse models identifies similarities and differences with human psoriasis", PLoS One, (20110000), vol. 6, no. 4, page e18266 | - VAN DER FITS LMOURITS SVOERMAN JSKANT MBOON LLAMAN JDCORNELISSEN FMUS AMFLORENCIA EPRENS EP, "Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis", J Immunol., (20090000), vol. 182, no. 9, doi:doi:10.4049/jimmunol.0802999, pages 5836 - 45, XP055376245 DOI: http://dx.doi.org/10.4049/jimmunol.0802999 | - SRIKANTA, D et al., "Cryptococcus neoformans infection", PLoS ONE, (20110000), vol. 6, no. 7, page e22773 | - HARRISON, T. S et al., "Cryptococcus neoformans", J Infect Disease, (20000000), vol. 182, pages 283 - 289 | - CANTON EPEMAN JVIUDES AQUINDOS GGOBERNADO MESPINEL-INGROFF A, "Minimum fungicidal concentrations of amphotericin B for bloodstream Candida species", Diagn Microbiol Infect Dis., (20030000), vol. 45, pages 203 - 6 | - GHANNOUM MAISHAM N, "Voriconazole and Caspofungin Cidality Against Non-Albicans Candida Species", Infectious Diseases in Clinical Practice, (20070000), vol. 15, no. 4, pages 250 - 253 | - ISHIZU, K.SUNOSE, N.YAMAZAKI, K.TSURUO, T.SADAHIRO, S.MAKUUCHI, H.YAMORI, T., "Development and Characterization of a Model of Liver Metastasis Using Human Colon Cancer HCT-116", Biol. Pharm. Bull., (20070000), vol. 30, no. 9, pages 1779 - 1783 |