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Extract from the Register of European Patents

EP About this file: EP3765476

EP3765476 - MODIFIED OLIGONUCLEOTIDES FOR USE IN TREATMENT OF TAUOPATHIES [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  18.12.2020
Database last updated on 19.10.2024
FormerThe international publication has been made
Status updated on  21.09.2019
Formerunknown
Status updated on  03.04.2019
Most recent event   Tooltip16.02.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Janssen Pharmaceutica NV
Turnhoutseweg 30
2340 Beerse / BE
[2021/03]
Inventor(s)01 / EBNETH, Andreas
Turnhoutseweg 30
2340 Beerse / BE
02 / VAN OUTRYVE D'YDEWALLE, Constantin
Turnhoutseweg 30
2340 Beerse / BE
03 / GRYAZNOV, Sergei
260E.Grand Ave.,2nd Floor South
San Francisco, CA 94080 / US
04 / MARTINEZ MONTERO, Saúl
260 E.Grand Ave., 2nd Floor, South
San Francisco, CA 94080 / US
05 / RAJWANSHI, Vivek Kumar
260 E Grand Ave, 2nd Floor South
San Francisco, CA 94080 / US
06 / BEIGELMAN, Leonid
260 E Grand Ave, 2nd Floor South
San Francisco, CA 94080 / US
 [2021/03]
Representative(s)Snaith, James Michael
Kilburn & Strode LLP
Lacon London
84 Theobalds Road
London WC1X 8NL / GB
[N/P]
Former [2021/03]Quaghebeur, Luc
Johnson & Johnson
Patent Law Department
Turnhoutseweg 30
2340 Beerse / BE
Application number, filing date19712535.413.03.2019
[2021/03]
WO2019EP56312
Priority number, dateUS201862642499P13.03.2018         Original published format: US 201862642499 P
[2021/03]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2019175260
Date:19.09.2019
Language:EN
[2019/38]
Type: A2 Application without search report 
No.:EP3765476
Date:20.01.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 19.09.2019 takes the place of the publication of the European patent application.
[2021/03]
Search report(s)International search report - published on:EP14.11.2019
ClassificationIPC:C07H21/00, C12N15/113, A61K31/7088, A61P25/28
[2021/03]
CPC:
C07H21/00 (EP,IL,KR); C12N15/113 (EP,IL,KR,US); A61K31/7125 (EP,IL,KR);
A61P25/28 (EP,IL,KR,US); C12N2310/11 (EP,IL,KR,US); C12N2310/315 (EP,IL,KR,US);
C12N2310/321 (EP,IL,KR,US); C12N2310/322 (EP,IL,KR); C12N2310/3341 (US);
C12N2310/335 (EP,IL,KR); C12N2310/341 (EP,IL,KR); C12N2310/345 (EP,IL,KR);
C12N2310/346 (US); C12N2310/3521 (IL); C12N2310/3525 (IL);
C12N2320/50 (US) (-)
C-Set:
C12N2310/321, C12N2310/3521 (EP);
C12N2310/322, C12N2310/3525 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/03]
Extension statesBA13.10.2020
ME13.10.2020
Validation statesKH13.10.2020
MA13.10.2020
MD13.10.2020
TN13.10.2020
TitleGerman:MODIFIZIERTE OLIGONUKLEOTIDE ZUR VERWENDUNG BEI DER BEHANDLUNG VON TAUOPATHIEN[2021/03]
English:MODIFIED OLIGONUCLEOTIDES FOR USE IN TREATMENT OF TAUOPATHIES[2021/03]
French:OLIGONUCLÉOTIDES MODIFIÉS ET MÉTHODES D'UTILISATION DANS LES TAUOPATHIES[2021/03]
Entry into regional phase13.10.2020National basic fee paid 
13.10.2020Designation fee(s) paid 
13.10.2020Examination fee paid 
Examination procedure13.10.2020Examination requested  [2021/03]
13.10.2020Date on which the examining division has become responsible
29.04.2021Amendment by applicant (claims and/or description)
Divisional application(s)EP21170299.8  / EP3922637
Fees paidRenewal fee
12.03.2021Renewal fee patent year 03
17.02.2022Renewal fee patent year 04
14.02.2023Renewal fee patent year 05
15.02.2024Renewal fee patent year 06
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Patent Court
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[YD]WO0118015  (GERON CORP [US], et al) [YD] 1-38,41,46-48,56,61-63,89-102 * abstract * * page 3, line 16 - page 5, line 14 *;
 [Y]WO2007107789  (SYLENTIS SA [ES], et al) [Y] 1-38,41,46-48,56,61-63,89-102 * abstract * * page 11, line 5 - page 14, line 25 *;
 [Y]US2014121261  (GRYAZNOV SERGEI M [US], et al) [Y] 1-38,41,46-48,56,61-63,89-102 * abstract * * [0106]-[0108] *;
 [Y]WO2014153236  (ISIS PHARMACEUTICALS INC [US]) [Y] 39-64 * abstract * * pages 73-76; table 9 *;
 [X]WO2015010135  (ISIS PHARMACEUTICALS INC [US]) [X] 39,40,42-45,49-55,57-60,64 * the whole document * * tables 9-66 * * pages 22-26; compounds Ia, IIa, IIIa, IVa, Va * * page 35, lines 5-20 *;
 [XY]WO2016126995  (BRISTOL MYERS SQUIBB CO [US], et al) [X] 39,40,42-45,49-55,57-60,64 * abstract * * [0166], [0246]-[0251], [0314]-[0347] * * figures 2, 3, 6, 7, 16 and 20 * [Y] 1-38,41,46-48,56,61-63,89-102;
 [XY]WO2017109679  (NOVARTIS AG [CH]) [X] 39,40,42-45,49-55,57-60,64 * abstract * * [0005]-[0011], [0027], [0030]-[0031], [0036], [0065]-[0078], [0083] * [Y] 1-38,41,46-48,56,61-63,89-102;
 [Y]  - KRISZTINA PONGRACZ ET AL, "Novel Short Oligonucleotide Conjugates as Inhibitors of Human Telomerase", NUCLEOSIDES, NUCLEOTIDES AND NUCLEIC ACIDS., US, (20031001), vol. 22, no. 5-8, doi:10.1081/NCN-120023085, ISSN 1525-7770, pages 1627 - 1629, XP055434021 [Y] 1-38,41,46-48,56,61-63,89-102 * the whole document *

DOI:   http://dx.doi.org/10.1081/NCN-120023085
 [Y]  - LOUIS P. CONWAY ET AL, "The synthesis, conformation and hydrolytic stability of an N,S-bridging thiophosphoramidate analogue of thymidylyl-3',5'-thymidine", ORGANIC & BIOMOLECULAR CHEMISTRY, (20160101), vol. 14, no. 30, doi:10.1039/C6OB01270A, ISSN 1477-0520, pages 7361 - 7367, XP055606690 [Y] 1-38,41,46-48,56,61-63,89-102 * the whole document * * compound 1 *

DOI:   http://dx.doi.org/10.1039/C6OB01270A
 [Y]  - R. SCHULTZ ET AL, "Oligo-2'-fluoro-2'-deoxynucleotide N3'-->P5' phosphoramidates: synthesis and properties", NUCLEIC ACIDS RESEARCH, (19960801), vol. 24, no. 15, doi:10.1093/nar/24.15.2966, pages 2966 - 2973, XP055626548 [Y] 39-64 * the whole document *

DOI:   http://dx.doi.org/10.1093/nar/24.15.2966
by applicantWO0118015
 US6268490
 US6525191
 US6770748
 US6794499
 US7034133
 US7053207
 US7084125
 US7217805
 US7314923
 US7569575
 US7696345
    - DEVOS et al., Sci Transl Med., (20170125), vol. 9, no. 374
    - HANGER et al., Trends Mol Med., (20090000), vol. 15, pages 112 - 9
    - WISCHIK et al., Proc Natl Acad Sci USA, (19880000), vol. 85, pages 4884 - 8
    - MORRIS et al., Neuron, (20110000), vol. 70, pages 410 - 26
    - Nucleic Acids Research, (19950000), vol. 23, no. 14, pages 2661 - 2668
    - Nucleic Acids Research, (19960000), vol. 24, no. 15, pages 2966 - 2973
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.