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Extract from the Register of European Patents

EP About this file: EP3693466

EP3693466 - METHOD AND SYSTEM FOR PREPARING RECOMBINANT ADENO-ASSOCIATED VIRUS, AND RECOMBINANT BACMID [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  25.08.2023
Database last updated on 14.06.2024
FormerThe patent has been granted
Status updated on  16.09.2022
FormerGrant of patent is intended
Status updated on  17.05.2022
FormerExamination is in progress
Status updated on  02.10.2020
FormerRequest for examination was made
Status updated on  10.07.2020
FormerThe international publication has been made
Status updated on  04.07.2020
Formerunknown
Status updated on  29.06.2019
Most recent event   Tooltip24.05.2024Lapse of the patent in a contracting state
New state(s): IT		published on 26.06.2024 [2024/26]
Applicant(s)For all designated states
Innovation Academy For Precision Measurement Science And Technology, Chinese Academy Of Sciences
West No. 30 Xiaohongshan
Wuchang District
Wuhan, Hubei 430071 / CN
[2021/30]
Former [2020/33]For all designated states
Wuhan Institute Of Physics And Mathematics, Chinese Academy of Sciences
West No.30 Xiao Hong Shan
Wuchang
Wuhan, Hubei 430071 / CN
Inventor(s)01 / WU, Yang
West No. 30
Xiaohongshan
Wuhang District
Wuhan
Hubei, China 430071 / CN
02 / XU, Fuqiang
West No. 30
Xiaohongshan
Wuhang District
Wuhan
Hubei, China 430071 / CN
03 / MEI, Ting
West No. 30
Xiaohongshan
Wuhang District
Wuhan
Hubei, China 430071 / CN
04 / JIANG, Liangyu
West No. 30
Xiaohongshan
Wuhang District
Wuhan
Hubei, China 430071 / CN
05 / HAN, Zengpeng
West No. 30
Xiaohongshan
Wuhang District
Wuhan
Hubei, China 430071 / CN
 [2020/33]
Representative(s)Niburska, Danuta
Kancelaria Patentowa
Al. 3 Maja 68 B
76-200 Slupsk / PL
[2022/42]
Former [2020/33]Hryszkiewicz, Danuta
Matthias Scholl, Inc.
Friedrichstrasse 123
10117 Berlin / DE
Application number, filing date19731865.229.03.2019
[2020/33]
WO2019CN80295
Priority number, dateCN20181161854228.12.2018         Original published format: CN201811618542
[2020/33]
Filing languageZH
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020133772
Date:02.07.2020
Language:ZH
[2020/27]
Type: A1 Application with search report 
No.:EP3693466
Date:12.08.2020
Language:EN
[2020/33]
Type: B1 Patent specification 
No.:EP3693466
Date:19.10.2022
Language:EN
[2022/42]
Search report(s)International search report - published on:CN02.07.2020
(Supplementary) European search report - dispatched on:EP08.04.2020
ClassificationIPC:C12N15/866, C12N7/00, C07K14/005, C12N15/86
[2020/33]
CPC:
C12N15/86 (EP,CN,KR); C07K14/005 (EP); C12N7/00 (CN);
C12N2710/14043 (CN); C12N2710/14122 (EP,KR); C12N2710/14144 (EP,KR);
C12N2710/14151 (EP); C12N2750/14143 (KR); C12N2750/14151 (EP,KR) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/33]
Extension statesBANot yet paid
MENot yet paid
Validation statesKHNot yet paid
MANot yet paid
MDNot yet paid
TNNot yet paid
TitleGerman:VERFAHREN, SYSTEM UND REKOMBINANTES BACMID ZUR HERSTELLUNG VON REKOMBINANTEM ADENO-ASSOZIIERTEM VIRUS[2020/33]
English:METHOD AND SYSTEM FOR PREPARING RECOMBINANT ADENO-ASSOCIATED VIRUS, AND RECOMBINANT BACMID[2020/33]
French:PROCÉDÉ ET SYSTÈME DE PRÉPARATION DE VIRUS ADÉNO-ASSOCIÉ RECOMBINÉ, ET BACMIDE RECOMBINÉ[2020/33]
Entry into regional phase28.06.2019Translation filed 
26.07.2019National basic fee paid 
26.07.2019Search fee paid 
26.07.2019Designation fee(s) paid 
26.07.2019Examination fee paid 
Examination procedure26.07.2019Examination requested  [2020/33]
08.04.2020Date on which the examining division has become responsible
09.04.2021Despatch of a communication from the examining division (Time limit: M04)
13.05.2021Reply to a communication from the examining division
18.06.2021Despatch of a communication from the examining division (Time limit: M04)
15.09.2021Reply to a communication from the examining division
17.12.2021Despatch of a communication from the examining division (Time limit: M02)
17.02.2022Reply to a communication from the examining division
01.03.2022Despatch of a communication from the examining division (Time limit: M02)
28.04.2022Reply to a communication from the examining division
18.05.2022Communication of intention to grant the patent
09.09.2022Fee for grant paid
09.09.2022Fee for publishing/printing paid
13.09.2022Receipt of the translation of the claim(s)
Opposition(s)20.07.2023No opposition filed within time limit [2023/39]
Fees paidRenewal fee
19.03.2021Renewal fee patent year 03
24.03.2022Renewal fee patent year 04
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Stay/Interruption28.06.2019Interruption of proceedings. Reason: representative has died[2021/02]
06.04.2021Resumption of proceedings[2021/16]
28.06.2019Interruption of proceedings. Reason: representative has died[2021/16]
Lapses during opposition  TooltipAL19.10.2022
AT19.10.2022
CZ19.10.2022
DK19.10.2022
EE19.10.2022
ES19.10.2022
FI19.10.2022
HR19.10.2022
IT19.10.2022
LT19.10.2022
LV19.10.2022
MC19.10.2022
NL19.10.2022
PL19.10.2022
RO19.10.2022
RS19.10.2022
SE19.10.2022
SI19.10.2022
SK19.10.2022
SM19.10.2022
NO19.01.2023
GR20.01.2023
IS19.02.2023
PT20.02.2023
IE29.03.2023
LU29.03.2023
BE31.03.2023
CH31.03.2023
LI31.03.2023
[2024/26]
Former [2024/12]AL19.10.2022
AT19.10.2022
CZ19.10.2022
DK19.10.2022
EE19.10.2022
ES19.10.2022
FI19.10.2022
HR19.10.2022
LT19.10.2022
LV19.10.2022
MC19.10.2022
NL19.10.2022
PL19.10.2022
RO19.10.2022
RS19.10.2022
SE19.10.2022
SI19.10.2022
SK19.10.2022
SM19.10.2022
NO19.01.2023
GR20.01.2023
IS19.02.2023
PT20.02.2023
IE29.03.2023
LU29.03.2023
BE31.03.2023
CH31.03.2023
LI31.03.2023
Former [2024/09]AL19.10.2022
AT19.10.2022
CZ19.10.2022
DK19.10.2022
EE19.10.2022
ES19.10.2022
FI19.10.2022
HR19.10.2022
LT19.10.2022
LV19.10.2022
MC19.10.2022
NL19.10.2022
PL19.10.2022
RO19.10.2022
RS19.10.2022
SE19.10.2022
SI19.10.2022
SK19.10.2022
SM19.10.2022
NO19.01.2023
GR20.01.2023
IS19.02.2023
PT20.02.2023
IE29.03.2023
LU29.03.2023
CH31.03.2023
LI31.03.2023
Former [2024/08]AL19.10.2022
AT19.10.2022
CZ19.10.2022
DK19.10.2022
EE19.10.2022
ES19.10.2022
FI19.10.2022
HR19.10.2022
LT19.10.2022
LV19.10.2022
MC19.10.2022
NL19.10.2022
PL19.10.2022
RO19.10.2022
RS19.10.2022
SE19.10.2022
SI19.10.2022
SK19.10.2022
SM19.10.2022
NO19.01.2023
GR20.01.2023
IS19.02.2023
PT20.02.2023
IE29.03.2023
LU29.03.2023
Former [2024/02]AL19.10.2022
AT19.10.2022
CZ19.10.2022
DK19.10.2022
EE19.10.2022
ES19.10.2022
FI19.10.2022
HR19.10.2022
LT19.10.2022
LV19.10.2022
MC19.10.2022
NL19.10.2022
PL19.10.2022
RO19.10.2022
RS19.10.2022
SE19.10.2022
SI19.10.2022
SK19.10.2022
SM19.10.2022
NO19.01.2023
GR20.01.2023
IS19.02.2023
PT20.02.2023
LU29.03.2023
Former [2023/51]AL19.10.2022
AT19.10.2022
CZ19.10.2022
DK19.10.2022
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FI19.10.2022
HR19.10.2022
LT19.10.2022
LV19.10.2022
MC19.10.2022
NL19.10.2022
PL19.10.2022
RO19.10.2022
RS19.10.2022
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SK19.10.2022
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GR20.01.2023
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LV19.10.2022
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Former [2023/22]AT19.10.2022
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FI19.10.2022
LT19.10.2022
NL19.10.2022
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PT20.02.2023
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NO19.01.2023
Former [2023/17]NL19.10.2022
Documents cited:Search[Y]WO2010055292  (LONDON SCHOOL OF HYGIENE & TRO [GB], et al) [Y] 1-10 * claims, examples, figures, in particlular figure 3 *;
 [XY]WO2013014294  (GENETHON [FR], et al) [X] 1,2,6-9 * figure 1; example -; claim - * [Y] 1-10;
 [XY]US2014349374  (GALIBERT LIONEL [FR], et al) [X] 1-3,5-10 * claims, examples, in particular paragraphs [0099]-[0106]; * [Y] 1-10;
 [Y]US2018155740  (WU YANG [CN], et al) [Y] 1* example -; claim - *;
 [XY]  - MERTEN O W, "AAV vector production: state of the art developments and remaining challenges", CELL AND GENE THERAPY INSIGHTS, (20161201), vol. 2, no. 5, doi:10.18609/cgti.2016.067, ISSN 2059-7800, pages 521 - 551, XP055649764 [X] 1-3,5-10 * page 536, right-hand column, paragraph 1; page 537, left-hand column, paragraph 2, figure 4D; * [Y] 1-10

DOI:   http://dx.doi.org/10.18609/cgti.2016.067
 [Y]  - BERGER I ET AL, "Baculovirus expression: old dog, new tricks", BIOENGINEERED, US, (20151021), vol. 6, no. 6, doi:10.1080/21655979.2015.1104433, ISSN 2165-5979, pages 316 - 322, XP055324481 [Y] 1-10 * page 319, column l, paragraph 2 - page 320, column m, paragraph 1; figure 2 *

DOI:   http://dx.doi.org/10.1080/21655979.2015.1104433
 [Y]  - MABASHI-ASAZUMA H ET AL, "A novel baculovirus vector for the production of nonfucosylated recombinant glycoproteins in insect cells", GLYCOBIOLOGY, US, (20131220), vol. 24, no. 3, doi:10.1093/glycob/cwt161, ISSN 0959-6658, pages 325 - 340, XP055681512 [Y] 1-10 * materials and methods;; page 331, column l, paragraph 2 - page 332, column r, paragraph 1; figure 6 *

DOI:   http://dx.doi.org/10.1093/glycob/cwt161
 [Y]  - Mabashi-Asazuma H ET AL, "Supplementary data", Glycobiology, doi:10.1093/glycob/cwt161, (20140301), pages 325 - 340, URL: https://academic.oup.com/glycob/article/24/3/325/1990459, (20200331), XP055681529 [Y] 1-10 * figure S3 *

DOI:   http://dx.doi.org/10.1093/glycob/cwt161
 [Y]  - LIANG C ET AL, "The Ac124 protein is not essential for the propagation ofAutographa californicamultiple nucleopolyhedrovirus, but it is a viral pathogenicity factor", ARCHIVES OF VIROLOGY, SPRINGER WIEN, AT, vol. 160, no. 1, doi:10.1007/S00705-014-2277-Y, ISSN 0304-8608, (20141108), pages 275 - 284, (20141108), XP035419839 [Y] 1-10 * materials and methods, figure 2, results, discussion *

DOI:   http://dx.doi.org/10.1007/s00705-014-2277-y
International search[A]CN106544325  (WUHAN INST PHYS & MATH CAS) [A] 1-10 * see entire document *;
 [Y]CN106916793  (WUHAN INST PHYS & MATH CAS) [Y] 1-10 * see claims 1-10 *;
 [Y]CN106987603  (WUHAN INST PHYS & MATH CAS) [Y] 1-10 * see embodiment 1 *;
 [Y]  - Database, Basic Sciences, (20131215), ISSN 1674-0246 [Y] 1-10 * , see pp. 13, 14 and 33 *
 [Y]  - GALIBERT L., "Origins of Truncated Supplementary Capsid Proteins in rAAV8 Vectors Produced with the Baculovirus System", PLoS One, (20181115), vol. 13, no. 11, doi:10.1371/journal.pone.0207414, ISSN 1932-6203, XP055649739 [Y] 2-5, 9, 10 * , see the abstract *

DOI:   http://dx.doi.org/10.1371/journal.pone.0207414
by applicantCN106916793
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