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Extract from the Register of European Patents

EP About this file: EP3746478

EP3746478 - THERAPIES AND METHODS TO TREAT TLR2-MEDIATED DISEASES AND DISORDERS [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  07.06.2024
Database last updated on 15.06.2024
FormerRequest for examination was made
Status updated on  06.11.2020
FormerThe international publication has been made
Status updated on  03.08.2019
Most recent event   Tooltip11.06.2024New entry: Despatch of examination report + time limit 
Applicant(s)For all designated states
The Regents of The University of California
1111 Franklin Street, 5th Floor
Oakland, CA 94607 / US
[2020/50]
Inventor(s)01 / WITZTUM, Joseph, L.
6912 Ofria Court
San Diego, CA 92120 / US
02 / TSIMIKAS, Sotirios
2802 Arnoldson Avenue
San Diego, CA 92122 / US
03 / QUE, Xuchu
17033 Albert Ave
San Diego, CA 92127 / US
 [2020/50]
Representative(s)Gill Jennings & Every LLP
The Broadgate Tower
20 Primrose Street
London EC2A 2ES / GB
[2020/50]
Application number, filing date19744139.729.01.2019
[2020/50]
WO2019US15723
Priority number, dateUS201862623276P29.01.2018         Original published format: US 201862623276 P
[2020/50]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019148204
Date:01.08.2019
Language:EN
[2019/31]
Type: A1 Application with search report 
No.:EP3746478
Date:09.12.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 01.08.2019 takes the place of the publication of the European patent application.
[2020/50]
Search report(s)International search report - published on:US01.08.2019
(Supplementary) European search report - dispatched on:EP22.12.2021
ClassificationIPC:C07K16/18, C07K16/44, A61P9/10, A61P17/00, A61P21/00, A61P25/00, A61P37/00, A61K39/00, C07K16/28
[2022/03]
CPC:
C07K16/2896 (EP); C07K16/18 (KR,US); A61K31/60 (US);
A61K39/39516 (US); A61K39/39533 (US); A61K9/0019 (US);
A61P17/00 (EP); A61P21/00 (EP); A61P25/00 (EP);
A61P37/00 (EP,KR); A61P37/06 (US); A61P9/10 (EP,KR);
A61K2039/505 (EP,KR); C07K2317/51 (US); C07K2317/515 (US);
C07K2317/52 (US); C07K2317/524 (US); C07K2317/565 (KR,US);
C07K2317/622 (EP,KR,US); C07K2317/76 (EP,US) (-)
Former IPC [2020/50]C07K16/18, C07K16/44
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/50]
TitleGerman:THERAPIEN UND VERFAHREN ZUR BEHANDLUNG VON TLR2-VERMITTELTEN KRANKHEITEN UND STÖRUNGEN[2020/50]
English:THERAPIES AND METHODS TO TREAT TLR2-MEDIATED DISEASES AND DISORDERS[2020/50]
French:THÉRAPIES ET MÉTHODES POUR TRAITER DES MALADIES ET DES TROUBLES MÉDIÉS PAR TLR2[2020/50]
Entry into regional phase10.07.2020National basic fee paid 
10.07.2020Search fee paid 
10.07.2020Designation fee(s) paid 
10.07.2020Examination fee paid 
Examination procedure10.07.2020Examination requested  [2020/50]
13.04.2021Despatch of communication of loss of particular rights: Claims {1}
18.08.2022Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
27.10.2022Amendment by applicant (claims and/or description)
10.06.2024Despatch of a communication from the examining division (Time limit: M04)
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
27.10.2022Request for further processing filed
27.10.2022Full payment received (date of receipt of payment)
Request granted
04.11.2022Decision despatched
08.06.2021Request for further processing filed
08.06.2021Full payment received (date of receipt of payment)
Request granted
17.06.2021Decision despatched
Fees paidRenewal fee
27.01.2021Renewal fee patent year 03
27.01.2022Renewal fee patent year 04
27.01.2023Renewal fee patent year 05
29.01.2024Renewal fee patent year 06
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Documents cited:Search[A]WO2011160845  (MEDIRISTA BIOTECHNOLOGIES AB [SE], et al);
 [X]US2015376268  (WITZTUM JOSEPH L [US], et al);
International search[Y]WO2011031460  (UNIV CALIFORNIA [US], et al) [Y] 10* para [0008 - 0009], [0012] *;
 [Y]WO2014131034  (UNIV CALIFORNIA [US]) [Y] 1-5, 7, 10 * para [0006], [0008], [0013], [0017], [0022], [0062], [00178] *;
 [Y]  - KADL, Alexandra et al., "Oxidized phospholipid-induced inflammation is mediated by Toll-like receptor 2", Free Radic Biol Med, (20110823), vol. 51, no. 1 0, pages 1903 - 1909, XP028319281 [Y] 1-5, 7, 10 * . Especially Abstract, pg 5, para 4; pg 2, para 2; pg 7, para 1 *

DOI:   http://dx.doi.org/10.1016/j.freeradbiomed.2011.08.026
 [Y]  - MORTAZAVI et al., "Down-regulation of TLR2, 3, 9 and Signaling Mediators, MyD88 and TRIF, Gene Transcript Levels in Patients with Kawasaki Disease Treated with IVIG", Iran J Allergy Asthma Immunol, (20150400), vol. 14, no. 2, pages 188 - 197, XP055628928 [Y] 2-5 * . Especially Abstract *
 [Y]  - SEIMON et al., "Atherogenic Lipids and Lipoproteins Trigger CD 36-TLR2-Dependent Apoptosis in Macrophages Undergoing Endoplasmic Reticulum Stress", Cell Metabolism, (20101103), vol. 12, no. 5, pages 467 - 482, XP055628932 [Y] 7 * . Especially Abstract, pg 469, para 1, col 2; pg 470, col 1, para 3; pg 479, col 1, para 1-2; pg 479, col 2, para 2 *

DOI:   http://dx.doi.org/10.1016/j.cmet.2010.09.010
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.